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Chemistry World January 6, 2010 Phillip Broadwith |
Enzymes do the twist The way enzyme catalysts bind molecules to speed up their reactions is not as simple as once thought, say chemists from the UK and Spain. |
Food Processing August 2007 Mark Anthony |
Nutrition Beyond the Trends: Connecting the Dots on Enzymes Lactase -- an enzyme that splits lactose into its constituent sugars, glucose and galactose -- can make short work of the lactose intolerance problem. |
Chemistry World January 17, 2010 Simon Hadlington |
Sugars synthesised with help of promiscuous enzyme European researchers have discovered a new way to make synthetically elusive sugar molecules that could lead to novel vaccine candidates and other medically important compounds. |
Chemistry World February 25, 2014 Simon Hadlington |
Synthetic 'textbook model' of a biological catalyst Scientists have developed a simple two-molecule chemical analogue of an enzyme and its substrate that neatly illustrates the fundamental principles of biological catalysis. |
Chemistry World May 29, 2015 Derek Lowe |
Magic molecule modifiers The synthesis of a new organic molecule can be approached in several ways. |
Chemistry World February 2011 |
Column: In the pipeline Enzymes have been giving chemists inferiority complexes since day one, says Derek Lowe. But there's no denying their potential |
Chemistry World September 24, 2012 Samantha Cheung |
Tumors reprogram nylon synthesis Cancer mutations have inspired a redesign of an enzyme to catalyze a key step in the bio-based production of adipic acid, a precursor to nylon. |
Chemistry World July 15, 2010 Simon Hadlington |
Synthetic enzyme catalyses Diels-Alder reaction The reaction is key to many organic syntheses and suggests that artificial enzymes could soon become part of the synthetic chemist's toolkit. |
Chemistry World June 17, 2010 Andrew Turley |
Biocatalyst improves diabetes drug production Researchers have developed an enzyme that can produce a difficult to form chiral amine in a best-selling diabetes therapy. |
Chemistry World March 6, 2008 Simon Hadlington |
Synthetic Enzymes Designed by Computer Scientists in the US have designed and built an artificial enzyme from scratch. |
Chemistry World February 21, 2007 Tom Westgate |
Complex Organic Molecules Teamed with Iodine Chemists have developed a method for constructing complex halogen-containing organic molecules from simple compounds in a single step. The discovery could pave the way for the synthesis of many potentially useful naturally occurring molecules. |
Chemistry World January 17, 2014 Phillip Broadwith |
Plug and play redox enzymes With the constant drive to make chemical synthesis ever cleaner, more energy-efficient and generate less waste -- both in research and industrial processes -- more and more chemists are looking to harness enzyme catalysis. |
Chemistry World March 8, 2007 Simon Hadlington |
Researchers Claim Antibiotic Holy Grail Researchers in Canada have revealed the structure of a key enzyme involved in the synthesis of bacterial cell walls. The finding opens up the possibility of developing new and improved antibiotics and overcoming the increasing problem of bacterial resistance to existing drugs. |
Chemistry World August 10, 2009 James Urquhart |
Stretching for reversible enzyme activation A new kind of biologically inspired nanomaterial that can be chemically turned on and off by mechanical stretching has been devised by French researchers. |
Wired July 20, 2009 Patrick di Justo |
What's Inside Enfamil Lipil Infant Formula? A detailed summary of the ingredients in this popular baby formula. |
Chemistry World November 26, 2012 Laura Howes |
Protein coat prepares catalyst for cascades By protecting a transition metal catalyst with a protein coat, scientists have managed to couple up biocatalysts and chemical catalysts to perform a cascade reaction. |
Chemistry World December 21, 2012 Laura Howes |
Engineered enzyme performs cyclopropanation by carbene transfer While biomimetic chemistry has been busy learning from nature, other chemists have been busy modifying enzymes to develop biocatalysts for other reactions. |
Chemistry World May 15, 2014 Jenifer Mizen |
Freeze-dried cells make better biocatalysts A biocatalytic cascade using mashed-up cells has overcome extraction and solubility problems associated with using enzymes in chemical syntheses. |
Chemistry World February 17, 2013 Simon Hadlington |
Enzyme nano-parcels sober up drunken mice Scientists in the US and China have invented a way to encapsulate teams of enzymes in a thin polymer shell. This enables the enzymes to carry out a series of sequential reactions within an enclosed space -- as happens in nature. |
Chemistry World November 14, 2013 James Urquhart |
Mysterious selectivity of nature's blowtorches solved US researchers have solved the long-standing mystery of how cytochrome P450 enzymes generate intermediates to perform demanding oxidations of inert C -- H bonds without damaging their fragile protein network in the process. |
Chemistry World April 14, 2006 Simon Hadlington |
Deciphering Hydrogen Tunnelling in Enzymes Researchers have thrown important new light on the phenomenon of hydrogen tunnelling in biological catalysts. The finding is likely to spark a debate among biochemists about the fundamental nature of enzymes. |
Chemistry World October 31, 2013 Derek Lowe |
Natural born chemists Organic chemists may not seem like a humble group. But we should be, because we are humiliated every hour of the day by what nature accomplishes through enzyme catalysis. |
Chemistry World January 8, 2014 Karl Collins |
Oxidation station Small molecules are making significant inroads -- with reactivity and selectivity approaching levels previously thought unachievable. |
Chemistry World March 25, 2011 Simon Hadlington |
New synthesis for chiral anticancer compound The promising anticancer compound nutlin-3 is likely to become more widely available to researchers thanks to a new synthetic protocol developed by US chemists. |
Chemistry World April 12, 2007 Simon Hadlington |
Fatty Acid Factory Revealed X-ray crystallographers have achieved the Herculean task of elucidating the architecture of one of biochemistry's most impressive molecular machines, the multi-enzyme fatty acid synthase. |
Chemistry World November 27, 2011 James Mitchell Crow |
Artificial enzymes close in on nature A synthetic metalloprotein that approaches the catalytic performance of a natural enzyme, despite its stripped-down structure, has been developed by a team of chemists in the US. |
Chemistry World January 30, 2015 Debbie Houghton |
Thin film approach to biocatalysis Taking an unconventional approach to biocatalysis has allowed scientists in Italy to improve enzyme recycling ability with a solvent-free reaction mixture |
Chemistry World September 24, 2007 Simon Hadlington |
Viral Nanoreactor Captures Single Molecules Researchers in the Netherlands have created a biochemical nanoreactor by cracking open a virus, removing its contents then reassembling the virus's protein coat around a single molecule of enzyme. |
Chemistry World November 26, 2010 Rebecca Brodie |
Printing on bioactive paper An enzyme printing process that prints the product of an enzyme-catalysed reaction, but not the enzyme molecule itself, has been designed by scientists in Australia to produce bioactive paper. |
Chemistry World November 25, 2014 James Urquhart |
Nanomolar chemistry enables 1500 experiments in a single day Chemists have conducted over 1500 chemistry experiments in under a day thanks to a miniaturized, high throughput automation platform they developed for identifying how synthetic molecules react under various conditions. |
Chemistry World September 21, 2009 Hayley Birch |
Enzymes inspire new catalyst design for hydrogen production A novel enzyme-based catalyst developed by UK and US researchers hints at new ways of designing catalysts for the water-gas shift reaction, an important industrial reaction in the production of high grade hydrogen. |
Chemistry World November 6, 2009 Phillip Broadwith |
Enzyme binds both sides of the mirror European chemists have discovered that both mirror-image forms of a particular compound can bind at the same time in the same site of an enzyme, a phenomenon that has never been seen before. |
Chemistry World January 24, 2013 Tamsin Cowley |
Environmentally friendly alternative to toxic heavy metals in paint Austrian scientists have shown that an environmentally friendly enzyme, laccase, can be used to replace toxic drying agents in paint. |
Chemistry World October 29, 2009 Lewis Brindley |
Cascading reactions in artificial cells Dutch researchers have started performing multi-step reactions inside artificial cells made from enzymes and polymers. |
AskMen.com October 14, 2001 Joshua Levine |
Lactose Intolerance Lactose intolerance, or the inability to digest milk and milk products, can be a burden, whether you are a bodybuilder (bodybuilders depend on milk as their primary source of protein) or a person just trying to live free of dietary hassles... |
Chemistry World March 4, 2013 Harriet Brewerton |
Co-factoring on a chip makes biocatalysis easy Stephan Mohr and colleagues have designed an efficient microfluidic biocatalysis device that uses and regenerates an artificial mediator, dimethyl viologen, which is cheaper than co-factors used currently. |
Chemistry World January 22, 2014 Eleanor Merritt |
Designer esters for complex carbohydrates Scientists based in the US have developed a new strategy to simplify the chemical synthesis of complex carbohydrates. |
Nutra Solutions October 10, 2007 Kerry Hughes |
Products: The "Spark of Life" The potential for enzyme use has not escaped scientists' imaginations, as enzymes are used in numerous industrial and medical applications. |
Chemistry World August 29, 2007 Ananyo Bhattacharya |
'Lost' Folate Enzyme Found After 30 Years US researchers have revealed the identity of an enzyme used by bacteria to make the essential B vitamin folate, 30 years after it was first isolated. |
Chemistry World August 30, 2009 Phillip Broadwith |
C-H oxidation proves its worth US researchers are going against the grain of total synthesis and developing new approaches to complex molecules. |
Chemistry World September 9, 2007 Simon Hadlington |
Sugaring the Pill Researchers in the US have made a key advance in efforts to bolt sugar molecules onto natural products in the search for new drugs. |
Chemistry World June 21, 2007 Simon Hadlington |
Boron is Key to Antifungal Agent Researchers have shown that the presence of a boron atom is key to an antifungal agent being developed to treat infections of fingernails and toenails. |
Chemistry World August 30, 2007 James Mitchell Crow |
Toxins' Synthesis Secret Cracked US chemists have discovered that using water instead of organic solvents is the key to understanding how algae make toxins called ladder polyethers. |
Chemistry World November 12, 2007 Simon Hadlington |
Coupled Enzymes May Spawn New Catalysts Chemists at the University of Oxford have created a new type of catalyst by attaching two enzymes to a microscopic flake of graphite. The system could be tailored to catalyze a range of reactions, the researchers say. |
Chemistry World October 25, 2010 |
Playing Games with Enzymes US researchers have shown that a solution of biological molecules can be taught to play any strategy of a simple board game against a human opponent and never lose. |
Chemistry World August 13, 2007 Simon Hadlington |
Nature Captured in a Test-Tube Two groups of researchers have demonstrated how a complex chain of reactions catalyzed by multiple enzymes can be reconstructed in the test tube to synthesize naturally occurring products that have potential therapeutic properties. |
Chemistry World April 21, 2010 Simon Hadlington |
Methane oxidising enzyme mystery solved The finding could lead to a cost-effective and environmentally clean method of methanol production for fuel and feedstock. |
Chemistry World August 28, 2014 Jennifer Newton |
Illuminating test measures fat in milk The first fluorescent probe for measuring fat levels in milk is poised to enhance milk quality control processes, particularly in resource-limited regions. |
Chemistry World June 9, 2013 James Urquhart |
Hairy proteins survive stomach trip Swiss researchers have discovered a way to stabilize enzymes in the digestive tract by linking polymers to the enzymes. |
Chemistry World August 13, 2009 Simon Hadlington |
Forcing enzyme activity New research has shown that physically stretching an enzyme can trigger its activity - even when the active site is not hidden in a 'cryptic' position. Mechanical force may play a more important role in biological molecular systems than previously realized. |