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Chemistry World January 6, 2010 Phillip Broadwith |
Enzymes do the twist The way enzyme catalysts bind molecules to speed up their reactions is not as simple as once thought, say chemists from the UK and Spain. |
Chemistry World July 15, 2010 Simon Hadlington |
Synthetic enzyme catalyses Diels-Alder reaction The reaction is key to many organic syntheses and suggests that artificial enzymes could soon become part of the synthetic chemist's toolkit. |
Chemistry World March 6, 2008 Simon Hadlington |
Synthetic Enzymes Designed by Computer Scientists in the US have designed and built an artificial enzyme from scratch. |
Chemistry World April 14, 2006 Simon Hadlington |
Deciphering Hydrogen Tunnelling in Enzymes Researchers have thrown important new light on the phenomenon of hydrogen tunnelling in biological catalysts. The finding is likely to spark a debate among biochemists about the fundamental nature of enzymes. |
Chemistry World November 26, 2012 Laura Howes |
Protein coat prepares catalyst for cascades By protecting a transition metal catalyst with a protein coat, scientists have managed to couple up biocatalysts and chemical catalysts to perform a cascade reaction. |
Chemistry World March 16, 2015 Elisabeth Ratcliffe |
Enzyme selectivity switch to benefit infant formula production Scientists in Austria who have redesigned the active site of an enzyme to switch its regioselectivity may have latched onto a new way to make molecules that are important for infant formula. |
Chemistry World June 17, 2010 Andrew Turley |
Biocatalyst improves diabetes drug production Researchers have developed an enzyme that can produce a difficult to form chiral amine in a best-selling diabetes therapy. |
Chemistry World May 21, 2009 Simon Hadlington |
Long-awaited structure of famous enzyme challenges the textbooks US researchers have uncovered a biochemical irony: a famous enzyme whose study led to some of the fundamental concepts of biological catalysis does not behave in the way that was previously thought. |
Chemistry World August 2, 2013 Amy Middleton-Gear |
Homogeneous catalyst made to act more like an enzyme Homogeneous catalytic systems which display selectivity in a mixture of similar substrates are rare. Now scientists have shown that encapsulating a homogeneous catalyst in a supramolecular host can give it a more discerning nature. |
Chemistry World August 10, 2009 James Urquhart |
Stretching for reversible enzyme activation A new kind of biologically inspired nanomaterial that can be chemically turned on and off by mechanical stretching has been devised by French researchers. |
Chemistry World September 24, 2012 Samantha Cheung |
Tumors reprogram nylon synthesis Cancer mutations have inspired a redesign of an enzyme to catalyze a key step in the bio-based production of adipic acid, a precursor to nylon. |
Chemistry World November 14, 2013 James Urquhart |
Mysterious selectivity of nature's blowtorches solved US researchers have solved the long-standing mystery of how cytochrome P450 enzymes generate intermediates to perform demanding oxidations of inert C -- H bonds without damaging their fragile protein network in the process. |
Chemistry World November 27, 2011 James Mitchell Crow |
Artificial enzymes close in on nature A synthetic metalloprotein that approaches the catalytic performance of a natural enzyme, despite its stripped-down structure, has been developed by a team of chemists in the US. |
Chemistry World April 12, 2007 Simon Hadlington |
Fatty Acid Factory Revealed X-ray crystallographers have achieved the Herculean task of elucidating the architecture of one of biochemistry's most impressive molecular machines, the multi-enzyme fatty acid synthase. |
Chemistry World January 24, 2013 Tamsin Cowley |
Environmentally friendly alternative to toxic heavy metals in paint Austrian scientists have shown that an environmentally friendly enzyme, laccase, can be used to replace toxic drying agents in paint. |
Chemistry World October 15, 2012 Simon Hadlington |
ExBox snares polycyclic aromatic hydrocarbons US chemists have designed a novel macrocyclic molecule that may be able to scavenge an important class of toxic hydrocarbons from the environment. |
Chemistry World January 17, 2014 Phillip Broadwith |
Plug and play redox enzymes With the constant drive to make chemical synthesis ever cleaner, more energy-efficient and generate less waste -- both in research and industrial processes -- more and more chemists are looking to harness enzyme catalysis. |
Chemistry World September 21, 2009 Hayley Birch |
Enzymes inspire new catalyst design for hydrogen production A novel enzyme-based catalyst developed by UK and US researchers hints at new ways of designing catalysts for the water-gas shift reaction, an important industrial reaction in the production of high grade hydrogen. |
Chemistry World August 13, 2009 Simon Hadlington |
Forcing enzyme activity New research has shown that physically stretching an enzyme can trigger its activity - even when the active site is not hidden in a 'cryptic' position. Mechanical force may play a more important role in biological molecular systems than previously realized. |
Chemistry World March 8, 2007 Simon Hadlington |
Researchers Claim Antibiotic Holy Grail Researchers in Canada have revealed the structure of a key enzyme involved in the synthesis of bacterial cell walls. The finding opens up the possibility of developing new and improved antibiotics and overcoming the increasing problem of bacterial resistance to existing drugs. |
Chemistry World February 6, 2015 Elisabeth Ratcliffe |
Exploiting the chirality of DNA DNA has emerged as an innovative way of controlling the chirality of a reaction product by binding catalysts in such a way that one enantiomer is preferentially generated. |
Chemistry World January 8, 2014 Karl Collins |
Oxidation station Small molecules are making significant inroads -- with reactivity and selectivity approaching levels previously thought unachievable. |
Chemistry World December 21, 2012 Laura Howes |
Engineered enzyme performs cyclopropanation by carbene transfer While biomimetic chemistry has been busy learning from nature, other chemists have been busy modifying enzymes to develop biocatalysts for other reactions. |
Chemistry World August 29, 2007 Ananyo Bhattacharya |
'Lost' Folate Enzyme Found After 30 Years US researchers have revealed the identity of an enzyme used by bacteria to make the essential B vitamin folate, 30 years after it was first isolated. |
Chemistry World October 1, 2010 Hayley Birch |
On-off catalyst mimics enzyme function US and Japanese researchers have created an enzyme-like catalyst whose activity can be switched on or off using small molecules. |
Chemistry World March 31, 2014 Ian Randall |
Shifting fluids with fuel-free enzyme pumps Microscopic, non-mechanical pumps that are activated and powered by the fluids they move have been developed by researchers from the US, Russia and Puerto Rico. |
Chemistry World January 30, 2009 Hayley Birch |
Nanocrystals Get in Shape for Catalysis New research in fine tuning the shape and size of nanoparticles could lead to important advances in catalysis. |
Chemistry World January 17, 2010 Simon Hadlington |
Sugars synthesised with help of promiscuous enzyme European researchers have discovered a new way to make synthetically elusive sugar molecules that could lead to novel vaccine candidates and other medically important compounds. |
Chemistry World May 21, 2009 James Urquhart |
Catalyst kinetics revealed French and UK scientists have developed a spectroscopy technique that has elucidated the reaction mechanism of a silver-alumina catalyst. |
Chemistry World February 20, 2013 Graham Hutchings |
Design and applications of single-site heterogeneous catalysts This monograph by John Meurig Thomas shows how heterogeneous catalysis lies at the heart of achieving the goal of making chemical processes greener and cleaner, and using sustainable routes. |
Chemistry World October 31, 2013 Derek Lowe |
Natural born chemists Organic chemists may not seem like a humble group. But we should be, because we are humiliated every hour of the day by what nature accomplishes through enzyme catalysis. |
Chemistry World February 2011 |
Column: In the pipeline Enzymes have been giving chemists inferiority complexes since day one, says Derek Lowe. But there's no denying their potential |
Chemistry World November 26, 2010 Rebecca Brodie |
Printing on bioactive paper An enzyme printing process that prints the product of an enzyme-catalysed reaction, but not the enzyme molecule itself, has been designed by scientists in Australia to produce bioactive paper. |
Chemistry World February 1, 2006 Michael Gross |
Chiral Catalysis on a Chip Chiral catalysis and analytical separation of the resulting enantiomers can now be performed on a single chip. The process could be scaled up to serve in high throughput screening for new enantioselective catalysts, claim the chemists who developed the chip. |
Chemistry World April 21, 2010 Simon Hadlington |
Methane oxidising enzyme mystery solved The finding could lead to a cost-effective and environmentally clean method of methanol production for fuel and feedstock. |
Chemistry World June 9, 2013 James Urquhart |
Hairy proteins survive stomach trip Swiss researchers have discovered a way to stabilize enzymes in the digestive tract by linking polymers to the enzymes. |