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Chemistry World August 11, 2008	Yeast Manufacture Morphine Precursor US scientists have developed a way to produce a group of medically important plant compounds in yeast. They say their technique could be used to manufacture drugs including painkillers and new cancer treatments.
Chemistry World August 29, 2007 Ananyo Bhattacharya	'Lost' Folate Enzyme Found After 30 Years US researchers have revealed the identity of an enzyme used by bacteria to make the essential B vitamin folate, 30 years after it was first isolated.
Chemistry World March 16, 2015 Elisabeth Ratcliffe	Enzyme selectivity switch to benefit infant formula production Scientists in Austria who have redesigned the active site of an enzyme to switch its regioselectivity may have latched onto a new way to make molecules that are important for infant formula.
Chemistry World February 2011	Column: In the pipeline Enzymes have been giving chemists inferiority complexes since day one, says Derek Lowe. But there's no denying their potential
Chemistry World January 6, 2010 Phillip Broadwith	Enzymes do the twist The way enzyme catalysts bind molecules to speed up their reactions is not as simple as once thought, say chemists from the UK and Spain.
Chemistry World January 17, 2014 Phillip Broadwith	Plug and play redox enzymes With the constant drive to make chemical synthesis ever cleaner, more energy-efficient and generate less waste -- both in research and industrial processes -- more and more chemists are looking to harness enzyme catalysis.
HHMI Bulletin Winter 2013 Olga Kuchment	Rickety for a Reason Imagine walking inside a building so flimsy that it shakes with every step, making you wonder what keeps it standing. HHMI early career scientist Sin Urban has been asking the same question about an unusual class of enzymes, the rhomboid proteases.
Chemistry World December 21, 2012 Laura Howes	Engineered enzyme performs cyclopropanation by carbene transfer While biomimetic chemistry has been busy learning from nature, other chemists have been busy modifying enzymes to develop biocatalysts for other reactions.
Chemistry World February 25, 2014 Simon Hadlington	Synthetic 'textbook model' of a biological catalyst Scientists have developed a simple two-molecule chemical analogue of an enzyme and its substrate that neatly illustrates the fundamental principles of biological catalysis.
Chemistry World November 3, 2014 Debbie Houghton	Engineered metalloenzyme catalyses Friedel -- Crafts reaction Reprogramming the genetic code of bacteria to incorporate an unnatural amino acid has allowed scientists in the Netherlands to create a new metalloenzyme capable of catalyzing an enantioselective reaction.
IEEE Spectrum February 2009 Monica Heger	Computer-Designed Drugs Could Thwart Antibiotic-Resistant Bacteria Researchers use computer algorithms to tweak enzymes that make antibiotics
Chemistry World October 31, 2013 Derek Lowe	Natural born chemists Organic chemists may not seem like a humble group. But we should be, because we are humiliated every hour of the day by what nature accomplishes through enzyme catalysis.
Chemistry World June 17, 2010 Andrew Turley	Biocatalyst improves diabetes drug production Researchers have developed an enzyme that can produce a difficult to form chiral amine in a best-selling diabetes therapy.
Chemistry World November 27, 2011 James Mitchell Crow	Artificial enzymes close in on nature A synthetic metalloprotein that approaches the catalytic performance of a natural enzyme, despite its stripped-down structure, has been developed by a team of chemists in the US.
Chemistry World November 12, 2007 Simon Hadlington	Coupled Enzymes May Spawn New Catalysts Chemists at the University of Oxford have created a new type of catalyst by attaching two enzymes to a microscopic flake of graphite. The system could be tailored to catalyze a range of reactions, the researchers say.
Chemistry World December 22, 2014 Andy Extance	Chemistry from the skies promises low-emission nylon raw material Mimicking the breakdown of atmospheric organic compounds has led to a cleaner way to make a key nylon raw material.
Chemistry World July 15, 2010 Simon Hadlington	Synthetic enzyme catalyses Diels-Alder reaction The reaction is key to many organic syntheses and suggests that artificial enzymes could soon become part of the synthetic chemist's toolkit.
Chemistry World August 10, 2009 James Urquhart	Stretching for reversible enzyme activation A new kind of biologically inspired nanomaterial that can be chemically turned on and off by mechanical stretching has been devised by French researchers.
Chemistry World January 17, 2010 Simon Hadlington	Sugars synthesised with help of promiscuous enzyme European researchers have discovered a new way to make synthetically elusive sugar molecules that could lead to novel vaccine candidates and other medically important compounds.
Chemistry World August 13, 2009 Simon Hadlington	Forcing enzyme activity New research has shown that physically stretching an enzyme can trigger its activity - even when the active site is not hidden in a 'cryptic' position. Mechanical force may play a more important role in biological molecular systems than previously realized.
Chemistry World September 23, 2011 Hayley Birch	Bio-Based Chemicals Under Environmental Scrutiny Bio-based chemicals made from renewable materials are helping to reduce the chemical industry's dependence on fossil fuels. But without vast improvements, some bio-based processes won't be any kinder to the environment than their petrochemical equivalents.
Chemistry World August 13, 2007 Simon Hadlington	Nature Captured in a Test-Tube Two groups of researchers have demonstrated how a complex chain of reactions catalyzed by multiple enzymes can be reconstructed in the test tube to synthesize naturally occurring products that have potential therapeutic properties.
Chemistry World April 14, 2006 Simon Hadlington	Deciphering Hydrogen Tunnelling in Enzymes Researchers have thrown important new light on the phenomenon of hydrogen tunnelling in biological catalysts. The finding is likely to spark a debate among biochemists about the fundamental nature of enzymes.
Chemistry World April 12, 2007 Simon Hadlington	Fatty Acid Factory Revealed X-ray crystallographers have achieved the Herculean task of elucidating the architecture of one of biochemistry's most impressive molecular machines, the multi-enzyme fatty acid synthase.
Chemistry World November 26, 2012 Laura Howes	Protein coat prepares catalyst for cascades By protecting a transition metal catalyst with a protein coat, scientists have managed to couple up biocatalysts and chemical catalysts to perform a cascade reaction.
Bio-IT World October 2006 Kevin Davies	Cracking the Cancer Genome Regardless of which technologies win out, or which centers win the lucrative sequencing contracts, the Cancer Genome Atlas has a sublime medical and scientific importance, underscored by the latest findings from Hopkins.
Chemistry World September 21, 2009 Hayley Birch	Enzymes inspire new catalyst design for hydrogen production A novel enzyme-based catalyst developed by UK and US researchers hints at new ways of designing catalysts for the water-gas shift reaction, an important industrial reaction in the production of high grade hydrogen.
Chemistry World March 6, 2008 Simon Hadlington	Synthetic Enzymes Designed by Computer Scientists in the US have designed and built an artificial enzyme from scratch.
Chemistry World September 9, 2007 Simon Hadlington	Sugaring the Pill Researchers in the US have made a key advance in efforts to bolt sugar molecules onto natural products in the search for new drugs.
Chemistry World January 21, 2010 Phil Taylor	Biosuccinic acid ready for take off? Faced with escalating oil prices that are likely to continue rising, the chemical industry is trying to find alternative sources for a number of the chemical ingredients derived from petroleum and other fossil-sources.
Chemistry World October 25, 2010	Playing Games with Enzymes US researchers have shown that a solution of biological molecules can be taught to play any strategy of a simple board game against a human opponent and never lose.
Chemistry World April 11, 2011 Mike Brown	One catalyst, two reactions Researchers in the US have designed a novel material that can catalyse two separate, sequential reactions to produce industrially relevant intermediates in one pot.
Chemistry World June 21, 2007 Simon Hadlington	Boron is Key to Antifungal Agent Researchers have shown that the presence of a boron atom is key to an antifungal agent being developed to treat infections of fingernails and toenails.
Nutra Solutions October 10, 2007 Kerry Hughes	Products: The "Spark of Life" The potential for enzyme use has not escaped scientists' imaginations, as enzymes are used in numerous industrial and medical applications.
Chemistry World March 8, 2007 Simon Hadlington	Researchers Claim Antibiotic Holy Grail Researchers in Canada have revealed the structure of a key enzyme involved in the synthesis of bacterial cell walls. The finding opens up the possibility of developing new and improved antibiotics and overcoming the increasing problem of bacterial resistance to existing drugs.
Chemistry World October 29, 2009 Lewis Brindley	Cascading reactions in artificial cells Dutch researchers have started performing multi-step reactions inside artificial cells made from enzymes and polymers.
Chemistry World June 9, 2013 James Urquhart	Hairy proteins survive stomach trip Swiss researchers have discovered a way to stabilize enzymes in the digestive tract by linking polymers to the enzymes.
Chemistry World May 29, 2015 Derek Lowe	Magic molecule modifiers The synthesis of a new organic molecule can be approached in several ways.
Chemistry World October 14, 2008 Simon Hadlington	Enzymes hit with double punch US chemists have made a small molecule that simultaneously blocks two key enzymes involved in the growth of cancer cells.
Wired August 2003 Jennifer Kahn	The End of Cancer (As we Know it) Diagnosis. Chemotherapy. Radiation. Slow painful death. No more. A new era of cancer treatment is dawning. Meet three scientists who are using the revelations of the Human Genome Project to reshape medicine.
Chemistry World December 12, 2006 Michael Gross	Ancient Protein Moonlights in the Eye A structural protein in the mouse eye lens is the evolutionary descendant of an ancient bacterial enzyme, researchers have found -- suggesting that moonlighting saved the protein from oblivion when its original role was taken over by a different family of enzymes.
Chemistry World February 17, 2013 Simon Hadlington	Enzyme nano-parcels sober up drunken mice Scientists in the US and China have invented a way to encapsulate teams of enzymes in a thin polymer shell. This enables the enzymes to carry out a series of sequential reactions within an enclosed space -- as happens in nature.
Chemistry World March 31, 2014 Ian Randall	Shifting fluids with fuel-free enzyme pumps Microscopic, non-mechanical pumps that are activated and powered by the fluids they move have been developed by researchers from the US, Russia and Puerto Rico.
Chemistry World November 14, 2013 James Urquhart	Mysterious selectivity of nature's blowtorches solved US researchers have solved the long-standing mystery of how cytochrome P450 enzymes generate intermediates to perform demanding oxidations of inert C -- H bonds without damaging their fragile protein network in the process.
Chemistry World May 15, 2014 Jenifer Mizen	Freeze-dried cells make better biocatalysts A biocatalytic cascade using mashed-up cells has overcome extraction and solubility problems associated with using enzymes in chemical syntheses.
Chemistry World October 16, 2014 Rebecca Trager	Bio-based chemicals on the rise in US The bio-based products and renewable chemical industry in the US is growing and offers significant economic benefits, including job creation in numerous sectors, according to the US Department of Agriculture
Food Processing August 2007 Mark Anthony	Nutrition Beyond the Trends: Connecting the Dots on Enzymes Lactase -- an enzyme that splits lactose into its constituent sugars, glucose and galactose -- can make short work of the lactose intolerance problem.
Chemistry World May 7, 2014 Emma Stoye	China's nitrous oxide emissions to triple by 2020 Emissions of nitrous oxide -- a potent greenhouse gas -- from China's chemical industries are increasing rapidly, and are set to triple by 2020 unless measures are put in place to stop them, new projections show.
Chemistry World March 4, 2013 Harriet Brewerton	Co-factoring on a chip makes biocatalysis easy Stephan Mohr and colleagues have designed an efficient microfluidic biocatalysis device that uses and regenerates an artificial mediator, dimethyl viologen, which is cheaper than co-factors used currently.
Chemistry World November 16, 2006 Simon Hadlington	Gene-Reading Enzyme Catapulted by Scrunch Power Two teams of researchers have solved a conundrum that has baffled molecular biologists for 20 years -- how the enzyme responsible for `reading' genes can release itself from the portion of DNA to which it initially binds extremely tightly.