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Chemistry World April 14, 2006 Simon Hadlington	Deciphering Hydrogen Tunnelling in Enzymes Researchers have thrown important new light on the phenomenon of hydrogen tunnelling in biological catalysts. The finding is likely to spark a debate among biochemists about the fundamental nature of enzymes.
Chemistry World August 10, 2009 James Urquhart	Stretching for reversible enzyme activation A new kind of biologically inspired nanomaterial that can be chemically turned on and off by mechanical stretching has been devised by French researchers.
Chemistry World August 22, 2011 Jon Cartwright	Manmade molecular machine goes to work Manmade molecules can generate similar forces to natural molecular machines, and could help chemists to design artificial molecular machines for meaningful tasks.
Chemistry World September 24, 2007 Simon Hadlington	Viral Nanoreactor Captures Single Molecules Researchers in the Netherlands have created a biochemical nanoreactor by cracking open a virus, removing its contents then reassembling the virus's protein coat around a single molecule of enzyme.
Chemistry World June 17, 2010 Andrew Turley	Biocatalyst improves diabetes drug production Researchers have developed an enzyme that can produce a difficult to form chiral amine in a best-selling diabetes therapy.
Chemistry World March 6, 2008 Simon Hadlington	Synthetic Enzymes Designed by Computer Scientists in the US have designed and built an artificial enzyme from scratch.
Chemistry World August 1, 2010 Mike Brown	Snapshots of mystery molecular structures Researchers have used atomic force microscopy to produce clear molecular images that can help determine the correct atomic structure of unknown organic molecules.
Chemistry World September 9, 2007 Simon Hadlington	Sugaring the Pill Researchers in the US have made a key advance in efforts to bolt sugar molecules onto natural products in the search for new drugs.
Chemistry World September 17, 2012 Jennifer Newton	Seeing cells under stress An analytical platform that imposes controlled mechanical strain onto live cells while monitoring changes in cell morphology and molecular signalling has been developed by scientists in Germany.
Chemistry World October 25, 2010	Playing Games with Enzymes US researchers have shown that a solution of biological molecules can be taught to play any strategy of a simple board game against a human opponent and never lose.
Chemistry World August 29, 2007 Ananyo Bhattacharya	'Lost' Folate Enzyme Found After 30 Years US researchers have revealed the identity of an enzyme used by bacteria to make the essential B vitamin folate, 30 years after it was first isolated.
Chemistry World November 26, 2010 Rebecca Brodie	Printing on bioactive paper An enzyme printing process that prints the product of an enzyme-catalysed reaction, but not the enzyme molecule itself, has been designed by scientists in Australia to produce bioactive paper.
Chemistry World April 2, 2009 Ned Stafford	Fluorescent probes take screening to next level Researchers have developed a new high-throughput screening technique that could shed light on the biochemical activities of numerous proteins about which little is currently known.
Chemistry World December 12, 2011 Simon Hadlington	Zwitterion approach to stabilizing drug proteins Researchers in the US have discovered a new way to stabilize and protect protein molecules without affecting the protein's biological activity.
Chemistry World August 5, 2011 David Bradley	Filming the roundabout production of cells' chemical fuel Japanese researchers have used a high-speed atomic force microscopy to shoot a movie of the tiny rotating enzyme that produces the chemical fuel for cells.
Chemistry World January 6, 2010 Phillip Broadwith	Enzymes do the twist The way enzyme catalysts bind molecules to speed up their reactions is not as simple as once thought, say chemists from the UK and Spain.
Chemistry World November 16, 2006 Simon Hadlington	Gene-Reading Enzyme Catapulted by Scrunch Power Two teams of researchers have solved a conundrum that has baffled molecular biologists for 20 years -- how the enzyme responsible for `reading' genes can release itself from the portion of DNA to which it initially binds extremely tightly.
Chemistry World March 4, 2013 Harriet Brewerton	Co-factoring on a chip makes biocatalysis easy Stephan Mohr and colleagues have designed an efficient microfluidic biocatalysis device that uses and regenerates an artificial mediator, dimethyl viologen, which is cheaper than co-factors used currently.
Chemistry World November 27, 2011 James Mitchell Crow	Artificial enzymes close in on nature A synthetic metalloprotein that approaches the catalytic performance of a natural enzyme, despite its stripped-down structure, has been developed by a team of chemists in the US.
Chemistry World February 25, 2014 Simon Hadlington	Synthetic 'textbook model' of a biological catalyst Scientists have developed a simple two-molecule chemical analogue of an enzyme and its substrate that neatly illustrates the fundamental principles of biological catalysis.
Chemistry World January 17, 2014 Phillip Broadwith	Plug and play redox enzymes With the constant drive to make chemical synthesis ever cleaner, more energy-efficient and generate less waste -- both in research and industrial processes -- more and more chemists are looking to harness enzyme catalysis.
Chemistry World September 24, 2012 Samantha Cheung	Tumors reprogram nylon synthesis Cancer mutations have inspired a redesign of an enzyme to catalyze a key step in the bio-based production of adipic acid, a precursor to nylon.
Chemistry World June 21, 2007 Simon Hadlington	Boron is Key to Antifungal Agent Researchers have shown that the presence of a boron atom is key to an antifungal agent being developed to treat infections of fingernails and toenails.
Chemistry World September 26, 2013 Akshat Rathi	First pictures of hydrogen bonds unveiled Researchers in China report the first visualization of a hydrogen bond using atomic force microscopy.
Chemistry World November 6, 2009 Phillip Broadwith	Enzyme binds both sides of the mirror European chemists have discovered that both mirror-image forms of a particular compound can bind at the same time in the same site of an enzyme, a phenomenon that has never been seen before.
Chemistry World May 21, 2009 Simon Hadlington	Long-awaited structure of famous enzyme challenges the textbooks US researchers have uncovered a biochemical irony: a famous enzyme whose study led to some of the fundamental concepts of biological catalysis does not behave in the way that was previously thought.
Chemistry World October 28, 2011 Laura Howes	Clicking Your Way to Synthetic Antibody Therapies Scientists have clicked together synthetic antibodies using the enzymes they want to target as a template. These synthetic antibodies can then be used to bind to the enzyme templates they were cast from, which could open up a whole new field of therapeutic molecules.
Chemistry World June 4, 2013 Emily Skinner	Homogeneous catalysis for nanoscale surface designs Scientists in France have combined homogeneous catalysis and atomic force microscopy to create intricate surface patterns.
Chemistry World February 17, 2013 Simon Hadlington	Enzyme nano-parcels sober up drunken mice Scientists in the US and China have invented a way to encapsulate teams of enzymes in a thin polymer shell. This enables the enzymes to carry out a series of sequential reactions within an enclosed space -- as happens in nature.
Reactive Reports November 2005 David Bradley	Water, Water How a strand of water just a few molecules thick could provide nanoscale clues about water's intriguing properties and why water is the dread enemy of atomic force microscopy.
Food Processing February 2009	Ingredient Round Up: Enzymes February's ingredient round-up focuses on enzymes
Chemistry World June 28, 2011 Russell Johnson	Screening for Alzheimer's Drugs in Tandem A simple assay based on sequential enzymatic reactions and a fluorescent sensor could help scientists to discover new Alzheimer's disease drugs.
Chemistry World April 21, 2010 Simon Hadlington	Methane oxidising enzyme mystery solved The finding could lead to a cost-effective and environmentally clean method of methanol production for fuel and feedstock.
Chemistry World May 26, 2010 Phillip Broadwith	Pain target enzyme's working made crystal clear An enzyme that influences how we feel pain and is a potential target for treating anxiety has been crystallised and its structure solved by US scientists.
Chemistry World April 12, 2007 Simon Hadlington	Fatty Acid Factory Revealed X-ray crystallographers have achieved the Herculean task of elucidating the architecture of one of biochemistry's most impressive molecular machines, the multi-enzyme fatty acid synthase.
Chemistry World August 11, 2008	Yeast Manufacture Morphine Precursor US scientists have developed a way to produce a group of medically important plant compounds in yeast. They say their technique could be used to manufacture drugs including painkillers and new cancer treatments.
Chemistry World November 6, 2009 Simon Hadlington	Boron-based compounds inhibit key HIV enzyme Researchers in the Czech Republic have shown that an unusual class of boron-containing compound can inhibit HIV protease, a key enzyme involved in replicating the virus that causes Aids.
HHMI Bulletin Winter 2013 Olga Kuchment	Rickety for a Reason Imagine walking inside a building so flimsy that it shakes with every step, making you wonder what keeps it standing. HHMI early career scientist Sin Urban has been asking the same question about an unusual class of enzymes, the rhomboid proteases.
Nutra Solutions October 10, 2007 Kerry Hughes	Products: The "Spark of Life" The potential for enzyme use has not escaped scientists' imaginations, as enzymes are used in numerous industrial and medical applications.
PC Magazine April 19, 2006 Sebastian Rupley	Pocket Doctor Vodafone introduced it's new biozoom device, which tests a person's water levels, enzyme levels, body fat percentage, and more, then displays the results on a mobile phone.
Chemistry World February 2011	Column: In the pipeline Enzymes have been giving chemists inferiority complexes since day one, says Derek Lowe. But there's no denying their potential
Chemistry World December 21, 2012 Laura Howes	Engineered enzyme performs cyclopropanation by carbene transfer While biomimetic chemistry has been busy learning from nature, other chemists have been busy modifying enzymes to develop biocatalysts for other reactions.
Chemistry World January 24, 2013 Tamsin Cowley	Environmentally friendly alternative to toxic heavy metals in paint Austrian scientists have shown that an environmentally friendly enzyme, laccase, can be used to replace toxic drying agents in paint.
Chemistry World June 9, 2013 James Urquhart	Hairy proteins survive stomach trip Swiss researchers have discovered a way to stabilize enzymes in the digestive tract by linking polymers to the enzymes.
Science News October 7, 2006	Timeline: From the October 3, 1936, Issue Steel and Concrete Hold 8,000,000-Pound Load... Living Organisms Found in Waters of the Dead Sea... Through Special Technique Enzyme is Viewed at Work...
Chemistry World November 21, 2006 Victoria Gill	Side-Effect-Free Chemotherapy Scientists have now developed an enzyme with the potential to eliminate the extreme fatigue, sickness and hair loss that result from this cell damage and strike fear into the hearts of cancer patients.
Chemistry World April 6, 2010 Lewis Brindley	Immune cells fight off nanotubes Carbon nanotubes can be degraded by an enzyme found in human immune cells, report US researchers.
Chemistry World August 21, 2014 Jonathan Midgley	Redirecting electrons boosts algal hydrogen generation Scientists have developed a highly targeted metabolic engineering technique to control the flow of electrons produced by the initial stages of photosynthesis in microalgae.
Chemistry World November 18, 2010 Hayley Birch	'Hunger hormone' activating enzyme holds promise as obesity target Blocking a key gut enzyme involved in the hunger response can reduce weight gain in mice, say US and Taiwanese researchers. The approach could eventually lead to treatments for obesity in humans that would work by damping down hunger pangs.
Chemistry World March 8, 2007 Simon Hadlington	Researchers Claim Antibiotic Holy Grail Researchers in Canada have revealed the structure of a key enzyme involved in the synthesis of bacterial cell walls. The finding opens up the possibility of developing new and improved antibiotics and overcoming the increasing problem of bacterial resistance to existing drugs.