Similar Articles

Browse Main Topics:

Business
Computers & Electronics
Education & Reference
Entertainment & Leisure
Family & Home
Finance & Investment
Health
Internet
Pets & Animals
Science & Technology
Society, Politics & Culture
Sports & Recreation

Similar Articles

Chemistry World September 9, 2007 Simon Hadlington	Sugaring the Pill Researchers in the US have made a key advance in efforts to bolt sugar molecules onto natural products in the search for new drugs.
Chemistry World July 27, 2012 Samantha Cheung	A sweeter approach to sugar synthesis Sugar chemists have developed a highly efficient synthetic pathway to produce a variety of oligosaccharides from scratch.
Chemistry World January 22, 2014 Eleanor Merritt	Designer esters for complex carbohydrates Scientists based in the US have developed a new strategy to simplify the chemical synthesis of complex carbohydrates.
Chemistry World March 23, 2009 Nina Notman	First auto carbohydrate synthesiser German researchers have unveiled the first fully automated carbohydrate synthesizer, which they hope will advance development of carbohydrate-based vaccines for the developing world.
Chemistry World March 8, 2006 Simon Hadlington	New Route to C-Glycoside Creation Overcomes Earlier Drawbacks A one-pot process for creating C-glycosides could help prepare robust analogues of naturally occurring carbohydrates. The technique could ultimately be used to make carbohydrate derivatives more widely available for use in applications from drugs to biosensors.
Chemistry World May 29, 2015 Derek Lowe	Magic molecule modifiers The synthesis of a new organic molecule can be approached in several ways.
Chemistry World September 2, 2007 Simon Hadlington	Sweet Approach to Tackling Cancer A promising new 'slimline' cancer vaccine that triggers a powerful immune response against excessive sugar molecules has been unveiled by researchers.
Chemistry World March 16, 2015 Elisabeth Ratcliffe	Enzyme selectivity switch to benefit infant formula production Scientists in Austria who have redesigned the active site of an enzyme to switch its regioselectivity may have latched onto a new way to make molecules that are important for infant formula.
Chemistry World October 10, 2012 Phillip Broadwith	Taming erythropoietin through synthesis US researchers have produced a fully synthetic version of erythropoietin, the glycoprotein responsible for regulating blood cell production.
Chemistry World May 20, 2015 Katrina Kramer	Taking the lead on drug discovery Researchers from the UK have developed a straightforward strategy for making compounds that have the potential to become clinical drugs.
Chemistry World August 11, 2015 Emma Cooper	Streamlined synthesis yields longer sugar chains By using bigger building blocks, scientists in the UK have shown they can make much longer oligosaccharide sequences than previously possible.
Chemistry World January 3, 2012 Simon Hadlington	One-pot synthesis creates anticancer candidates Researchers in Germany have developed a simple, rapid and high-yielding cascade synthesis of a collection of polycyclic compounds that resemble indole alkaloid natural products and which interfere with cell division.
Chemistry World December 9, 2011 Jennifer Newton	Turning Bacteria's Shield Into a Weapon Against it Scientists in Germany have synthesised the core part of a sugar compound produced by the pathogenic bacteria responsible for meningitis - Neisseria meningitides - which could be used in a vaccine for meningococcal diseases, in particular meningitis B.
Chemistry World March 25, 2011 Simon Hadlington	New synthesis for chiral anticancer compound The promising anticancer compound nutlin-3 is likely to become more widely available to researchers thanks to a new synthetic protocol developed by US chemists.
Chemistry World July 10, 2013 Karl Collins	An 'Aye' for details Today, using methods developed by masters of their trade, the modern greats of total synthesis demonstrate that almost any molecule can be prepared given time and effort.
Chemistry World January 18, 2009 Hayley Birch	Plants reprogrammed to produce potential drugs Plants could one day function as factories for producing anti-cancer drugs, say US scientists.
Chemistry World August 18, 2011 Helen Bache	Sugar injection to beat hospital infection A carbohydrate from the surface of the most virulent strain of the bacterium Clostridium difficile has been synthesised by chemists in Germany. The molecule could be used to develop a vaccine against the infection.
Chemistry World August 29, 2007 Ananyo Bhattacharya	'Lost' Folate Enzyme Found After 30 Years US researchers have revealed the identity of an enzyme used by bacteria to make the essential B vitamin folate, 30 years after it was first isolated.
Chemistry World November 28, 2013	Put the chemistry back in medicinal chemistry Today, synthetic skill is valued and appreciated much less in medicinal chemistry than in chemical development, though it is equally important for both. Much of the blame lies with the mismeasurement of productivity.
Chemistry World November 25, 2014 James Urquhart	Nanomolar chemistry enables 1500 experiments in a single day Chemists have conducted over 1500 chemistry experiments in under a day thanks to a miniaturized, high throughput automation platform they developed for identifying how synthetic molecules react under various conditions.
Chemistry World February 18, 2010 Hayley Birch	First sugars needed silicates to survive Earth's first complex sugars could have formed with a little help from silicate ions, according to a new study by US chemists.
Chemistry World November 3, 2008 Simon Hadlington	Organic synthesis set for auto-pilot Peptides are routinely made by machines that couple together amino acid components. Could organic synthesis ever get this simple?
Chemistry World September 24, 2007 Simon Hadlington	Viral Nanoreactor Captures Single Molecules Researchers in the Netherlands have created a biochemical nanoreactor by cracking open a virus, removing its contents then reassembling the virus's protein coat around a single molecule of enzyme.
Chemistry World April 12, 2007 Simon Hadlington	Fatty Acid Factory Revealed X-ray crystallographers have achieved the Herculean task of elucidating the architecture of one of biochemistry's most impressive molecular machines, the multi-enzyme fatty acid synthase.
Chemistry World August 30, 2007 James Mitchell Crow	Toxins' Synthesis Secret Cracked US chemists have discovered that using water instead of organic solvents is the key to understanding how algae make toxins called ladder polyethers.
Chemistry World May 1, 2008 Simon Hadlington	Click chemistry illuminates embryo development US researchers have smuggled modified sugar molecules into a developing zebrafish embryo and then used 'click chemistry' to snap a fluorescent tag onto them to watch cells and tissues forming.
Wired June 2001	Verge Automated Oligosaccharide Synthesizer can produce a polymer composed of 12 monosaccharides in about 18 hours - almost a hundred times faster than other methods...
Chemistry World September 29, 2015	Navigating chemical space How big is chemistry? I don't mean how important is it, or how many people do it, but rather, how many molecules are there that we could make?
Chemistry World September 4, 2008 Fred Campbell	Two catalysts better than one US researchers have cracked a long standing problem in chemical synthesis - the catalytic alpha-alkylation of aldehydes - by combining two catalysts in one pot.
Chemistry World March 2012	Lead-oriented synthesis Ian Churcher and Alan Nadin call for the development of more robust synthetic tools to improve small molecule survival rates in the perilous journey from lead to drug
Chemistry World February 2011	Column: In the pipeline Enzymes have been giving chemists inferiority complexes since day one, says Derek Lowe. But there's no denying their potential
Chemistry World September 18, 2008 Simon Hadlington	Bio-petroleum made from sugars James Dumesic's team at the University of Wisconsin-Madison set out to convert simple sugars into hydrocarbons that could be blended to make vehicle fuels that are identical to the ones we use today.
Chemistry World March 8, 2007 Simon Hadlington	Researchers Claim Antibiotic Holy Grail Researchers in Canada have revealed the structure of a key enzyme involved in the synthesis of bacterial cell walls. The finding opens up the possibility of developing new and improved antibiotics and overcoming the increasing problem of bacterial resistance to existing drugs.
Chemistry World September 24, 2012 Samantha Cheung	Tumors reprogram nylon synthesis Cancer mutations have inspired a redesign of an enzyme to catalyze a key step in the bio-based production of adipic acid, a precursor to nylon.
Chemistry World June 17, 2010 Andrew Turley	Biocatalyst improves diabetes drug production Researchers have developed an enzyme that can produce a difficult to form chiral amine in a best-selling diabetes therapy.
Chemistry World February 21, 2007 Tom Westgate	Complex Organic Molecules Teamed with Iodine Chemists have developed a method for constructing complex halogen-containing organic molecules from simple compounds in a single step. The discovery could pave the way for the synthesis of many potentially useful naturally occurring molecules.
Chemistry World January 6, 2010 Phillip Broadwith	Enzymes do the twist The way enzyme catalysts bind molecules to speed up their reactions is not as simple as once thought, say chemists from the UK and Spain.
Chemistry World February 5, 2014 Jenifer Mizen	Protein-free and low sugar -- not a new diet, a new vaccine A Streptococcus pneumonia vaccine with fewer sugar units and no antigenic protein is not only easier to produce but could also induce a superior immune response to the vaccine currently in clinical use.
Chemistry World June 16, 2011	Forming the First Sugars with Formose Reactions Hydrothermal synthesis could provide greener synthesis methods as well as information about the origin of life.
Chemistry World March 2011 Paul Docherty	Column: Totally Synthetic Discovered independently by two chemists in the 1870s, it's remarkable that 140 years later, science is still tweaking and improving the aldol reaction.
Chemistry World November 6, 2009 Phillip Broadwith	Enzyme binds both sides of the mirror European chemists have discovered that both mirror-image forms of a particular compound can bind at the same time in the same site of an enzyme, a phenomenon that has never been seen before.
Chemistry World January 17, 2014 Phillip Broadwith	Plug and play redox enzymes With the constant drive to make chemical synthesis ever cleaner, more energy-efficient and generate less waste -- both in research and industrial processes -- more and more chemists are looking to harness enzyme catalysis.
Chemistry World November 26, 2010 Rebecca Brodie	Printing on bioactive paper An enzyme printing process that prints the product of an enzyme-catalysed reaction, but not the enzyme molecule itself, has been designed by scientists in Australia to produce bioactive paper.
Chemistry World June 9, 2013 James Urquhart	Hairy proteins survive stomach trip Swiss researchers have discovered a way to stabilize enzymes in the digestive tract by linking polymers to the enzymes.
Chemistry World May 29, 2013 Paul Docherty	Pactamycin A member of a 'rival' field stating that a molecule is 'inaccessible by synthetic organic chemistry' is like a red rag to the proverbial bull. This challenge surrounds analogs of pactamycin, a complex cyclopentane-based target with an exceptionally potent biological profile.
Chemistry World December 12, 2011 Simon Hadlington	Zwitterion approach to stabilizing drug proteins Researchers in the US have discovered a new way to stabilize and protect protein molecules without affecting the protein's biological activity.
IEEE Spectrum February 2009 Monica Heger	Computer-Designed Drugs Could Thwart Antibiotic-Resistant Bacteria Researchers use computer algorithms to tweak enzymes that make antibiotics
Chemistry World April 2007 Derek Lowe	Opinion: In the Pipeline Natural products can be ridiculously complicated. The sheer difficulty of the enterprise is traditionally what made pharmaceutical companies hire people who had worked in total synthesis. But, is total synthesis research still worth the effort?
Chemistry World November 2008 Paul Docherty	Column: Totally Synthetic Vannusal B -- This is a classic case of misassigned identity - the structure published by the researchers who first isolated the compound from its natural source has been recreated via total synthesis, and found wanting.
Chemistry World March 12, 2015 Matthew Gunther	Chemical building blocks produce a wellspring of organic molecules Scientists in the US have developed an automated platform to create small organic molecules from a set of simple of chemical building blocks.