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Chemistry World March 4, 2013 Harriet Brewerton |
Co-factoring on a chip makes biocatalysis easy Stephan Mohr and colleagues have designed an efficient microfluidic biocatalysis device that uses and regenerates an artificial mediator, dimethyl viologen, which is cheaper than co-factors used currently. |
Chemistry World January 17, 2014 Phillip Broadwith |
Plug and play redox enzymes With the constant drive to make chemical synthesis ever cleaner, more energy-efficient and generate less waste -- both in research and industrial processes -- more and more chemists are looking to harness enzyme catalysis. |
Chemistry World November 26, 2012 Laura Howes |
Protein coat prepares catalyst for cascades By protecting a transition metal catalyst with a protein coat, scientists have managed to couple up biocatalysts and chemical catalysts to perform a cascade reaction. |
Chemistry World September 21, 2009 Hayley Birch |
Enzymes inspire new catalyst design for hydrogen production A novel enzyme-based catalyst developed by UK and US researchers hints at new ways of designing catalysts for the water-gas shift reaction, an important industrial reaction in the production of high grade hydrogen. |
Chemistry World May 29, 2015 Derek Lowe |
Magic molecule modifiers The synthesis of a new organic molecule can be approached in several ways. |
Chemistry World May 15, 2014 Jenifer Mizen |
Freeze-dried cells make better biocatalysts A biocatalytic cascade using mashed-up cells has overcome extraction and solubility problems associated with using enzymes in chemical syntheses. |
Chemistry World August 10, 2009 James Urquhart |
Stretching for reversible enzyme activation A new kind of biologically inspired nanomaterial that can be chemically turned on and off by mechanical stretching has been devised by French researchers. |
Chemistry World November 3, 2014 Debbie Houghton |
Engineered metalloenzyme catalyses Friedel -- Crafts reaction Reprogramming the genetic code of bacteria to incorporate an unnatural amino acid has allowed scientists in the Netherlands to create a new metalloenzyme capable of catalyzing an enantioselective reaction. |
Chemistry World January 24, 2013 Tamsin Cowley |
Environmentally friendly alternative to toxic heavy metals in paint Austrian scientists have shown that an environmentally friendly enzyme, laccase, can be used to replace toxic drying agents in paint. |
Chemistry World May 30, 2013 Andy Extance |
Catalyst duo exerts powerful stereocontrol Chemists from the Swiss Federal Institute of Technology, ETH Zurich, have teamed chiral catalysts in pairs to selectively drive a reaction towards desired stereoisomeric products with high selectivity. |
Chemistry World March 6, 2008 Simon Hadlington |
Synthetic Enzymes Designed by Computer Scientists in the US have designed and built an artificial enzyme from scratch. |
Chemistry World May 21, 2009 James Urquhart |
Catalyst kinetics revealed French and UK scientists have developed a spectroscopy technique that has elucidated the reaction mechanism of a silver-alumina catalyst. |
Chemistry World February 17, 2013 Simon Hadlington |
Enzyme nano-parcels sober up drunken mice Scientists in the US and China have invented a way to encapsulate teams of enzymes in a thin polymer shell. This enables the enzymes to carry out a series of sequential reactions within an enclosed space -- as happens in nature. |
Chemistry World January 6, 2010 Phillip Broadwith |
Enzymes do the twist The way enzyme catalysts bind molecules to speed up their reactions is not as simple as once thought, say chemists from the UK and Spain. |
Chemistry World June 17, 2010 Andrew Turley |
Biocatalyst improves diabetes drug production Researchers have developed an enzyme that can produce a difficult to form chiral amine in a best-selling diabetes therapy. |
Nutra Solutions October 10, 2007 Kerry Hughes |
Products: The "Spark of Life" The potential for enzyme use has not escaped scientists' imaginations, as enzymes are used in numerous industrial and medical applications. |
Chemistry World April 14, 2006 Simon Hadlington |
Deciphering Hydrogen Tunnelling in Enzymes Researchers have thrown important new light on the phenomenon of hydrogen tunnelling in biological catalysts. The finding is likely to spark a debate among biochemists about the fundamental nature of enzymes. |
Chemistry World October 31, 2013 Derek Lowe |
Natural born chemists Organic chemists may not seem like a humble group. But we should be, because we are humiliated every hour of the day by what nature accomplishes through enzyme catalysis. |
Chemistry World July 15, 2010 Simon Hadlington |
Synthetic enzyme catalyses Diels-Alder reaction The reaction is key to many organic syntheses and suggests that artificial enzymes could soon become part of the synthetic chemist's toolkit. |
Chemistry World January 13, 2011 Sarah Corcoran |
Unclogging the problems of flow chemistry US scientists have found a way to stop solid byproducts clogging channels in continuous flow reactors, a problem that has hampered their progress for use in manufacturing pharmaceuticals. |
Chemistry World March 16, 2015 Elisabeth Ratcliffe |
Enzyme selectivity switch to benefit infant formula production Scientists in Austria who have redesigned the active site of an enzyme to switch its regioselectivity may have latched onto a new way to make molecules that are important for infant formula. |
Chemistry World September 13, 2013 Anthony King |
Spinning a catalytic yarn Scientists in Germany have revealed a revolutionary new support for catalysts -- cloth. They succeeded in permanently securing organocatalysts onto nylon using ultraviolet light, without any need for chemical modification. |
Chemistry World December 21, 2012 Laura Howes |
Engineered enzyme performs cyclopropanation by carbene transfer While biomimetic chemistry has been busy learning from nature, other chemists have been busy modifying enzymes to develop biocatalysts for other reactions. |
Chemistry World February 2011 |
Column: In the pipeline Enzymes have been giving chemists inferiority complexes since day one, says Derek Lowe. But there's no denying their potential |
Chemistry World October 10, 2014 Simon Ward |
The organic chemistry of drug design and drug action (3rd edition) The organic chemistry of drug design and drug action is a long-running textbook, first appearing over 20 years ago. |
Chemistry World April 26, 2007 Richard Van Noorden |
Hydrogen Busters go Synthetic Chemists have created a small molecule which mimics the way natural enzymes chew up hydrogen. The model should inspire designs for new catalysts that can break up hydrogen in fuel cells; or (running in reverse) help produce the fuel for a hydrogen economy. |
Chemistry World April 18, 2012 Elinor Richards |
Homogeneous Catalyst Recovery Made Easier Scientists have now found a way to recover homogeneous catalysts at the end of a chemical reaction that doesn't suffer from the slow reaction rates that affect current catalyst recovery systems. |
Chemistry World October 29, 2009 Lewis Brindley |
Cascading reactions in artificial cells Dutch researchers have started performing multi-step reactions inside artificial cells made from enzymes and polymers. |
Chemistry World August 30, 2007 James Mitchell Crow |
Toxins' Synthesis Secret Cracked US chemists have discovered that using water instead of organic solvents is the key to understanding how algae make toxins called ladder polyethers. |
Chemistry World February 1, 2006 Michael Gross |
Chiral Catalysis on a Chip Chiral catalysis and analytical separation of the resulting enantiomers can now be performed on a single chip. The process could be scaled up to serve in high throughput screening for new enantioselective catalysts, claim the chemists who developed the chip. |
Chemistry World October 26, 2006 Victoria Gill |
Volcanoes Reveal the Secret of the Origin of Life Life began with a chemical reaction under the sea over four billion years ago. That is the claim of a German scientist whose team has recreated a crucial part of the reaction, synthesizing all the necessary ingredients for a living organism. |
Chemistry World August 26, 2010 Simon Hadlington |
A self-optimising microreactor system Chemists in the US have developed a microreactor system which automatically calculates the optimal conditions for the chemical reaction it is undertaking. |
Chemistry World August 13, 2007 Simon Hadlington |
Nature Captured in a Test-Tube Two groups of researchers have demonstrated how a complex chain of reactions catalyzed by multiple enzymes can be reconstructed in the test tube to synthesize naturally occurring products that have potential therapeutic properties. |
Chemistry World November 2007 Derek Lowe |
Column: In the Pipeline Chemists are finally going with the flow. |
Chemistry World February 20, 2012 James Urquhart |
Unusual kinetics of catalyst revealed US researchers have elucidated the unusual reaction kinetics of C-H activation by the palladium(II) catalyst (Pd(OAc) 2). |
Chemistry World February 2008 Dylan Stiles |
Column: Bench Monkey Cast a skeptical eye over new ideas in chemistry. |
Chemistry World May 26, 2015 |
Catching the runaways I think each cohort of industrial chemists has a runaway industrial reaction that defines their generation. |
Chemistry World November 12, 2007 Simon Hadlington |
Coupled Enzymes May Spawn New Catalysts Chemists at the University of Oxford have created a new type of catalyst by attaching two enzymes to a microscopic flake of graphite. The system could be tailored to catalyze a range of reactions, the researchers say. |
Chemistry World October 23, 2013 Manisha Lalloo |
NMR thermometer takes reactor's temperature Scientists in the US have used NMR to create temperature maps of reactions taking place inside catalytic reactors. Their technique opens the door to an easy, non-invasive way to discover hot and cold 'spots' inside reactors. |
Chemistry World November 21, 2011 David Bradley |
Zombie reaction returns from the dead An oscillating reaction that apparently stops after 10 hours, but is then resurrected spontaneously several hours later, has been discovered by a group of chemistry students at the Mito Dai-ni senior high school in Ibaraki, Japan. |
Chemistry World November 26, 2010 Rebecca Brodie |
Printing on bioactive paper An enzyme printing process that prints the product of an enzyme-catalysed reaction, but not the enzyme molecule itself, has been designed by scientists in Australia to produce bioactive paper. |
Chemistry World July 6, 2015 Abigail Hallowes |
From chip fat to biofuel Researchers from Singapore and China have developed a cheap and green catalytic system for turning fatty acids into fuel that doesn't require hydrogen or a solvent. |
Chemistry World March 11, 2011 Elinor Richards |
Making baby food safer Scientists from Spain have used a lab on a chip device to quickly analyse levels of zearalenone, a contaminant, in infant foods with a detection limit below legislative requirements. |
Chemistry World August 22, 2014 Derek Lowe |
Death of a reagent Anyone who's been practicing organic chemistry for a while can think back to reactions and reagents that were once in far wider use than they are today. |
Chemistry World November 27, 2011 James Mitchell Crow |
Artificial enzymes close in on nature A synthetic metalloprotein that approaches the catalytic performance of a natural enzyme, despite its stripped-down structure, has been developed by a team of chemists in the US. |
IndustryWeek August 1, 2004 Tonya Vinas |
Making Waves Dubbed the 'third wave' of biotechnology, after medicine and agriculture, industrial biotechnology is promising to reshape manufacturing. |
IEEE Spectrum February 2009 Monica Heger |
Computer-Designed Drugs Could Thwart Antibiotic-Resistant Bacteria Researchers use computer algorithms to tweak enzymes that make antibiotics |
Wired September 24, 2007 Evan Ratliff |
One Molecule Could Cure Our Addiction to Oil Scientists have long known how to turn trees into ethanol, but doing it profitably is another matter. |