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Chemistry World
March 8, 2007
Simon Hadlington
Researchers Claim Antibiotic Holy Grail Researchers in Canada have revealed the structure of a key enzyme involved in the synthesis of bacterial cell walls. The finding opens up the possibility of developing new and improved antibiotics and overcoming the increasing problem of bacterial resistance to existing drugs. mark for My Articles similar articles
HHMI Bulletin
Nov 2011
Dave Mosher
A New PACE for Laboratory Evolution Researchers have found a way to accelerate evolution of molecules by harnessing viruses. mark for My Articles similar articles
Chemistry World
June 1, 2012
Simon Hadlington
Protein architecture with atomic precision Researchers have made a key breakthrough in designing and building geometrically defined nanostructures from proteins with unprecedented accuracy. mark for My Articles similar articles
Chemistry World
November 27, 2013
Jennifer Newton
A cytochrome from scratch Artificial proteins could be closer to participating in natural biochemical pathways after researchers show that bacteria will process amino acid sequences entirely unrelated to any natural protein to produce a fully functioning cytochrome. mark for My Articles similar articles
Bio-IT World
June 12, 2002
Mark D. Uehling
Putting Proteins in Their Place Will a 'periodic table' of proteins help classify the ungainly beasts? mark for My Articles similar articles
Chemistry World
July 15, 2010
Simon Hadlington
Synthetic enzyme catalyses Diels-Alder reaction The reaction is key to many organic syntheses and suggests that artificial enzymes could soon become part of the synthetic chemist's toolkit. mark for My Articles similar articles
Chemistry World
February 3, 2013
Andy Extance
Enzyme draws nanopore protein sequencing nearer US scientists at the University of California, Santa Cruz, have made a key step towards nanopore protein sequencing, thanks to an 'unfoldase' enzyme. Mark Akeson's team exploited this enzyme to unravel proteins and pull them through nanopores. mark for My Articles similar articles
Chemistry World
November 27, 2011
James Mitchell Crow
Artificial enzymes close in on nature A synthetic metalloprotein that approaches the catalytic performance of a natural enzyme, despite its stripped-down structure, has been developed by a team of chemists in the US. mark for My Articles similar articles
Chemistry World
October 27, 2006
Richard Van Noorden
Synthetic Origami Folds Like Natural Enzymes Researchers have synthesised a large organic molecule that folds up like a small protein, though its backbone is entirely non-biological. The achievement is a step along the path to producing truly synthetic enzymes in the laboratory. mark for My Articles similar articles
Chemistry World
February 18, 2008
John Bonner
Flicking the Acetyl Switch A strain of Escherichia coli that can produce proteins containing an acetylated version of the amino acid lysine could help to reveal how acetylation changes the function of hundreds of proteins inside cells. mark for My Articles similar articles
Chemistry World
June 14, 2011
A New Spin on Protein NMR A new technique will allow researchers to study protein structure in greater detail using NMR. mark for My Articles similar articles
Chemistry World
December 12, 2011
Simon Hadlington
Zwitterion approach to stabilizing drug proteins Researchers in the US have discovered a new way to stabilize and protect protein molecules without affecting the protein's biological activity. mark for My Articles similar articles
Bio-IT World
October 10, 2003
Jeffrey Skolnick
Protein Structure Prediction in Drug Discovery Indications are that structure prediction can assist in the automated assignment of proteins to known pathways. mark for My Articles similar articles
Food Processing
August 2007
Mark Anthony
Nutrition Beyond the Trends: Connecting the Dots on Enzymes Lactase -- an enzyme that splits lactose into its constituent sugars, glucose and galactose -- can make short work of the lactose intolerance problem. mark for My Articles similar articles
Chemistry World
April 12, 2007
Lewis Brindley
Preserved T. Rex Proteins Assist Evolution Studies Palaeontologists and biochemists have joined forces to identify proteins from a 68-million-year-old T. Rex, showing that organic matter containing biological information can be preserved for enormous lengths of time under the right conditions. mark for My Articles similar articles
Chemistry World
December 19, 2007
Simon Hadlington
Snapshot of Proteins Linked to Autism Researchers in France and the US have caught on camera the gentle embrace between two proteins that sit on either side of the junction between nerve cells. It's this short circuit that has thought to cause some types of autism. mark for My Articles similar articles
Chemistry World
June 25, 2013
Michael Gross
A foaming protein from the horse's mouth Researchers in the UK have solved the structure of this protein, yielding tantalizing hints to a novel kind of surface activity and to evolutionary connections to other examples. mark for My Articles similar articles
Chemistry World
January 19, 2011
Jon Cartwright
Modified protein binders give shortcut to drugs The method, which involves attaching polypeptides to the binders, could help reduce the work required to develop protein binders into safer drugs. mark for My Articles similar articles
Chemistry World
October 24, 2008
Hayley Birch
Proteins swap partners UK researchers have discovered that proteins which use metal cofactors can be surprisingly promiscuous metal binders, happily taking up the 'wrong' metal. mark for My Articles similar articles
Chemistry World
December 23, 2015
Bones of contention Can protein in dinosaur bones survive for millions of years? Rachel Brazil explores the evidence. mark for My Articles similar articles
Chemistry World
December 20, 2011
Simon Hadlington
pH adjustable protein micro-lenses Scientists in China have used a common protein to create tiny optical lenses, a few tens of micrometres in diameter, whose focus can be adjusted simply by changing the pH of the surrounding medium. mark for My Articles similar articles
Chemistry World
August 26, 2008
Fred Campbell
High-throughput protein microarrays on the way A new method to rapidly generate protein microarrays has been developed by UK researchers at the University of Manchester. mark for My Articles similar articles
HHMI Bulletin
February 2011
Michele Solis
Right Before Your Eyes Coupling protein sequence to function, thousands of variants at a time. mark for My Articles similar articles
Chemistry World
March 6, 2007
Michael Gross
Nature's Supramolecular Chemistry Researchers studying a bacterial molybdenum-storage protein have teamed up with inorganic chemists to resolve the structure of the storage protein's central cavity. mark for My Articles similar articles
Bio-IT World
August 15, 2005
Robert M. Frederickson
What's 'Post' About Postgenomic? Bioinformatics tools can help organize and study genomic sequences that were discovered in the '90s. The tools help with tasks like analyzing gene expression, predicting protein structure and function, and establishing networks of interacting protein in cells. mark for My Articles similar articles
Chemistry World
June 21, 2007
Simon Hadlington
Boron is Key to Antifungal Agent Researchers have shown that the presence of a boron atom is key to an antifungal agent being developed to treat infections of fingernails and toenails. mark for My Articles similar articles
Chemistry World
November 14, 2013
James Urquhart
Mysterious selectivity of nature's blowtorches solved US researchers have solved the long-standing mystery of how cytochrome P450 enzymes generate intermediates to perform demanding oxidations of inert C -- H bonds without damaging their fragile protein network in the process. mark for My Articles similar articles
Prepared Foods
February 2008
Sharon Book
Article: Protein Ingredients for Health and Texture A variety of soy, dairy and egg proteins are available for the food formulator to obtain the desired texture in a food or beverage. mark for My Articles similar articles
Chemistry World
April 14, 2006
Simon Hadlington
Deciphering Hydrogen Tunnelling in Enzymes Researchers have thrown important new light on the phenomenon of hydrogen tunnelling in biological catalysts. The finding is likely to spark a debate among biochemists about the fundamental nature of enzymes. mark for My Articles similar articles
Chemistry World
January 5, 2007
Victoria Gill
PEG Makes Cheaper Drugs for Developing Countries UK and Indian scientists have embarked on a collaboration to develop a new protein-based treatment for hepatitis C, which they say will provide an affordable drug urgently needed in countries where resources are limited. mark for My Articles similar articles
Chemistry World
October 31, 2013
Derek Lowe
Natural born chemists Organic chemists may not seem like a humble group. But we should be, because we are humiliated every hour of the day by what nature accomplishes through enzyme catalysis. mark for My Articles similar articles
Chemistry World
April 25, 2013
James Urquhart
Filler to patch up ancient silk delicates Chinese researchers have found a way to restore and strengthen ancient, fragile silk fabrics using an enzyme-mediated reaction to fill in tiny cracks in the fibers. mark for My Articles similar articles
Chemistry World
June 2009
Michael Gross
Bubble-wrapped frogs Tropical frogs create remarkable protein foams to protect their spawn. Exploration of the underlying chemistry has only just begun mark for My Articles similar articles
Chemistry World
October 8, 2008
Sarah Houlton
Artificial protein chemistry licensed to industry UK researchers are licensing to industry their method of making artificial proteins by chemically modifying individual amino acid structures. mark for My Articles similar articles
Chemistry World
December 21, 2006
Henry Nicholls
Silent SNPs Serve up a Structural Surprise The sequence of amino acids no longer dictates the structure and function of a protein according to a surprising new paper. mark for My Articles similar articles
Chemistry World
June 6, 2010
Philip Ball
Blood-like liquid protein formed A liquid form of the oxygen-binding protein myoglobin retains its biological function even though it seems virtually water-free, researchers have found. mark for My Articles similar articles
AskMen.com
Bryan Tomek
Supplements Guide When it comes to supplements, understanding fact from fiction can be crucial to your health. mark for My Articles similar articles
Chemistry World
September 29, 2010
Hayley Birch
Protein folding: knotted or not A new study may help scientists unravel the complex problem of protein folding. The study suggests knotted proteins, which present a particular challenge to folding experts, could be untied with a couple of well-targeted tugs. mark for My Articles similar articles
Chemistry World
February 24, 2012
Simon Hadlington
Botox 'bodyguard' gives protein protection Researchers have discovered how one of the most potent toxins known to man can survive in the human stomach and digestive tract. mark for My Articles similar articles
Chemistry World
October 27, 2014
Tim Wogan
Folding rules used to build unnatural proteins Scientists in the UK and US have designed and synthesized unnatural protein structures, using theoretical calculations to explore the factors affecting protein folding and stability. mark for My Articles similar articles
Chemistry World
November 13, 2014
Katrina Kramer
Persuading proteins to form porous polyhedra Researchers in the US have designed a hollow cube out of naturally occurring proteins, something that was previously only possible with DNA. mark for My Articles similar articles
Chemistry World
June 9, 2013
James Urquhart
Hairy proteins survive stomach trip Swiss researchers have discovered a way to stabilize enzymes in the digestive tract by linking polymers to the enzymes. mark for My Articles similar articles
Chemistry World
November 2006
Philip Ball
Opinion: The Crucible Here are some of the latest instalments in the ongoing story of how protein misfolding causes neurodegenerative diseases -- a story that is not solely about developing clinical treatments or preventative medicines, but which goes to the heart of proteins' role as the stuff of life. mark for My Articles similar articles
Chemistry World
August 2, 2012
Philip Ball
Polymer replacement for the hydration shell The sheath of water molecules, called a hydration shell, that gives protein molecules the flexibility to do their catalytic job can be replaced by polymers, according to Adam Perriman of the University of Bristol and his coworkers. mark for My Articles similar articles
Chemistry World
November 26, 2012
Laura Howes
Protein coat prepares catalyst for cascades By protecting a transition metal catalyst with a protein coat, scientists have managed to couple up biocatalysts and chemical catalysts to perform a cascade reaction. mark for My Articles similar articles
Bio-IT World
April 15, 2003
Malorye Branca
Beyond the Blueprint How will the wealth of data emanating from the human genome and allied technologies impact research on health and disease? mark for My Articles similar articles
Chemistry World
December 5, 2007
Ananyo Bhattacharya
Structural Snapshot Shows Monster Protein A structural snapshot of a protein capsule has revealed details of the largest cellular component ever imaged by x-ray crystallography. mark for My Articles similar articles
Chemistry World
August 10, 2009
James Urquhart
Stretching for reversible enzyme activation A new kind of biologically inspired nanomaterial that can be chemically turned on and off by mechanical stretching has been devised by French researchers. mark for My Articles similar articles
Chemistry World
September 24, 2007
Simon Hadlington
Viral Nanoreactor Captures Single Molecules Researchers in the Netherlands have created a biochemical nanoreactor by cracking open a virus, removing its contents then reassembling the virus's protein coat around a single molecule of enzyme. mark for My Articles similar articles
Reactive Reports
Issue 51
David Bradley
Protein Crystals Trapped Researchers have developed a new technique for crystallizing proteins, which could open up a whole range of materials to this powerful analytical technique. mark for My Articles similar articles