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Chemistry World January 17, 2010 Simon Hadlington	Sugars synthesised with help of promiscuous enzyme European researchers have discovered a new way to make synthetically elusive sugar molecules that could lead to novel vaccine candidates and other medically important compounds.
Chemistry World July 27, 2012 Samantha Cheung	A sweeter approach to sugar synthesis Sugar chemists have developed a highly efficient synthetic pathway to produce a variety of oligosaccharides from scratch.
Chemistry World August 2010 Paul Docherty	Column: Totally Synthetic The total synthesis of macrolide targets is now a relatively mature field. Any synthesis that bucks these trends grabs attention, with a recent publication of dictyosphaeric acid A by Richard Taylor's team at the University of York, UK, a case in point.
Chemistry World October 1, 2012 Paul Docherty	Prostaglandin F2I There's been no shortage of grant funding for synthetic chemistry of the prostaglandins, keeping some of the finest minds in organic chemistry engaged over the last five decades.
Chemistry World January 22, 2014 Eleanor Merritt	Designer esters for complex carbohydrates Scientists based in the US have developed a new strategy to simplify the chemical synthesis of complex carbohydrates.
Chemistry World August 1, 2013 James Urquhart	Total synthesis outshines biotech route to anticancer drug US scientists have developed the first efficient and scalable route for the total synthesis of ingenol -- a plant-derived diterpenoid used to treat precancerous skin legions.
Chemistry World June 1, 2012 Paul Docherty	atrop-Abyssomicin C This member of the abyssomicin family is the only one to achieve bacteria-bashing prowess, and is also the only one to feature atropisomerism -- a relatively unusual form of stereoisomerism in naturally occurring species
Chemistry World November 27, 2008 Lewis Brindley	Bryostatin Synthesis Made Simple US chemists have dramatically shortened the synthesis of byrostatin 16, one of a family of natural products that show promising activity against cancer but can't easily be extracted from nature or made artificially.
Chemistry World January 21, 2013 Michael Parkin	Flow synthesis for anticancer drug UK chemists have used a combination of flow chemistry methods with solid-supported scavengers and reagents to synthesize the active pharmaceutical ingredient, imatinib, of the anticancer drug Gleevec.
Chemistry World March 23, 2009 Nina Notman	First auto carbohydrate synthesiser German researchers have unveiled the first fully automated carbohydrate synthesizer, which they hope will advance development of carbohydrate-based vaccines for the developing world.
Chemistry World May 29, 2013 Paul Docherty	Pactamycin A member of a 'rival' field stating that a molecule is 'inaccessible by synthetic organic chemistry' is like a red rag to the proverbial bull. This challenge surrounds analogs of pactamycin, a complex cyclopentane-based target with an exceptionally potent biological profile.
Chemistry World August 16, 2009 Tom Bond	Catalyst free carbon-carbon bond formation The method offers an environmentally friendly way to form one of the most important bonds in organic synthesis.
Chemistry World September 2, 2007 Simon Hadlington	Sweet Approach to Tackling Cancer A promising new 'slimline' cancer vaccine that triggers a powerful immune response against excessive sugar molecules has been unveiled by researchers.
Reactive Reports Issue 63 David Bradley	Natural Copy Cat While plants convert carbon dioxide into sugar and oxygen, chemists are having a more difficult time finding an efficient method for converting carbon dioxide into useful fuels.
Chemistry World June 2010 Paul Docherty	Column: Totally Synthetic Although its chemistry is mature and varied, my use of silicon reagents in my synthetic forays has been limited to a somewhat clumsy use of hydroxyl protecting groups.
Chemistry World October 29, 2014	Lycopodium alkaloids Not all natural products are created equal. A glance at the total synthesis literature from the past decade is enough to discover that some molecules attract a lot more attention than others.
Reactive Reports David Bradley	Subjective Suboxide Carbon monoxide and carbon dioxide are probably the best known molecules containing just carbon and oxygen, but they do form others, such as carbon suboxide (C3O2), which is one of the most stable.
Chemistry World August 2007 Derek Lowe	Opinion: In the Pipeline Process chemists just don't get the credit they deserve.
Chemistry World July 6, 2006 Michael Gross	Insecticide Simplified A rapid, flexible way to make variants of potent insecticide molecules known as spinosyns could help to combat the growing problem of insect resistance, according to German chemists.
Chemistry World June 19, 2013 John Hayward	Science of synthesis workbench edition: water in organic synthesis If a chemist is looking to do chemistry in (or on) water at the bench, Water in organic synthesis by Shu Kobayashi will be their guide.
Chemistry World March 7, 2014 Elinor Richards	Shortcut to carbon dioxide plastics holds sequestration promise Japanese scientists have cleared a significant hurdle in using carbon dioxide as a chemical feedstock and made a polymer that contains almost a third of the gas by weight.
Chemistry World October 12, 2007 James Mitchell Crow	Flow Reactors Enter the Rapids Continuous flow chemistry's promise to shake up synthesis gathered momentum this month, with the first Uniqsis Flow Chemistry Symposium.
Chemistry World April 2007 Derek Lowe	Opinion: In the Pipeline Natural products can be ridiculously complicated. The sheer difficulty of the enterprise is traditionally what made pharmaceutical companies hire people who had worked in total synthesis. But, is total synthesis research still worth the effort?
Chemistry World April 2011 Paul Docherty	Column: Totally Synthetic Reactions in the synthesis of guanacastepene N. Discovered in fungi growing on trees in the Guanacaste conservation area in Costa Rica, several syntheses of this family have appeared in the decade since their isolation.
Chemistry World January 24, 2014 Michael Gross	Self-assembing carbohydrates behave like proteins Researchers have used ultracentrifugation to show that some carbohydrates behave like proteins, sticking together in complex, well-ordered arrangements that readily dissolve and reform in response to concentration changes.