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Chemistry World October 22, 2008 Susan Aldridge |
A greener route to amines Researchers based in Israel have developed an easier way to make troublesome primary amines, using a new ruthenium catalyst. |
Chemistry World July 1, 2012 Paul Docherty |
Vincorine Cage-structured natural products are some of the most appealing (if perhaps not appetising) targets for organic chemists -- perhaps due to their obvious intricacy of form, but also because of their structural rigidity. |
Chemistry World February 20, 2012 James Urquhart |
Unusual kinetics of catalyst revealed US researchers have elucidated the unusual reaction kinetics of C-H activation by the palladium(II) catalyst (Pd(OAc) 2). |
Chemistry World June 10, 2010 Simon Hadlington |
Elusive intermediate snared Chemists in Germany have succeeded in trapping an elusive intermediate involved in a key synthetic reaction catalysed by an organic molecule. |
Chemistry World February 22, 2008 James Mitchell Crow |
Rhodium Fast Tracks Route to Lactones Chemists in Canada have developed an efficient new way to make lactones, chemical components of many natural products and drugs. |
Chemistry World February 4, 2011 Elinor Richards |
Strychnine in just six steps Strychnine, best known as a poison but also used medicinally as a stimulant, can now be synthesised in just six steps, say US scientists. |
Chemistry World April 25, 2010 Hayley Birch |
New strategy yields best ever catalyst for ammonia decomposition US researchers have developed a new strategy for predicting bimetallic catalysts. |
Chemistry World August 14, 2014 Elisabeth Ratcliffe |
Photoredox route to medically-important heterocycles Researchers in the US have developed a new photo catalyzed coupling reaction that could provide a pathway to a huge number of biologically active compounds. |
Chemistry World December 12, 2007 Jonathan Edwards |
Aqueous Fischer-Tropsch is Clean and Green Chinese chemists have carried out the Fischer-Tropsch reaction in water for the first time, bringing a greener route to hydrocarbon fuels a step closer. |
Chemistry World August 16, 2009 Tom Bond |
Catalyst free carbon-carbon bond formation The method offers an environmentally friendly way to form one of the most important bonds in organic synthesis. |
Chemistry World June 1, 2006 Michael Gross |
New Twists on Catalysis Chemists around the world have discovered several new twists to improve the performance of asymmetric catalysts in hydrogenation reactions. |
Chemistry World October 16, 2015 Philippa Matthews |
One pot recipe for incompatible catalytic transformations Researchers from the US have demonstrated a new catalyst support structure allowing two incompatible catalysts to work in tandem. |
Chemistry World January 13, 2011 Mike Brown |
Palladium helps gold catalyst go green Researchers have developed a catalyst that efficiently converts toluene into a useful industrial intermediate in a much greener process than traditional methods. |
Chemistry World March 25, 2011 Simon Hadlington |
New synthesis for chiral anticancer compound The promising anticancer compound nutlin-3 is likely to become more widely available to researchers thanks to a new synthetic protocol developed by US chemists. |
Chemistry World February 21, 2008 Lewis Brindley |
Esters Made Easy with Indium Indium is the basis of a novel catalyst designed to make useful cyclic esters. This catalyst could greatly simplify the production of chiral dihydropyranones, important structural elements in many natural products and pharmaceuticals. |
Chemistry World April 10, 2008 Mark Peplow |
'Pot-in-a-Pot' Technique Makes Impossible Cascade Reactions Easy A simple technique that nests a series of reaction vessels could help chemists avoid the tedium and expense of purifying organic compounds after each step of a long synthesis. |
Chemistry World July 14, 2011 Simon Hadlington |
Natural Products Made Via a Single Parent Molecule Chemists in the US have taken inspiration from nature to devise a new concept for rapidly and efficiently synthesising structurally diverse natural products from a single common precursor. |
Chemistry World February 2011 Paul Docherty |
Column: Totally Synthetic Although most of the natural products I've discussed have had biological activity at the core of the rationale for their synthesis, most organic chemists will admit that an unusual chemical structure is by far the stronger draw. |
Chemistry World September 13, 2013 Anthony King |
Spinning a catalytic yarn Scientists in Germany have revealed a revolutionary new support for catalysts -- cloth. They succeeded in permanently securing organocatalysts onto nylon using ultraviolet light, without any need for chemical modification. |
Chemistry World February 27, 2012 Phillip Broadwith |
Bending carbonyl reactivity rules Belgian chemists have uncovered a method to bypass the standard reactivity hierarchy of carbonyl compounds, allowing a ketone or ester to be reduced in the presence of a more reactive aldehyde. |
Chemistry World July 15, 2010 Simon Hadlington |
Synthetic enzyme catalyses Diels-Alder reaction The reaction is key to many organic syntheses and suggests that artificial enzymes could soon become part of the synthetic chemist's toolkit. |
Chemistry World May 30, 2013 Andy Extance |
Catalyst duo exerts powerful stereocontrol Chemists from the Swiss Federal Institute of Technology, ETH Zurich, have teamed chiral catalysts in pairs to selectively drive a reaction towards desired stereoisomeric products with high selectivity. |
Chemistry World April 12, 2012 Simon Hadlington |
Recruiting electrophiles for organic cross-coupling Chemists in the US have taken an unconventional approach to carbon cross-coupling and in doing so have potentially opened the door to the rapid and efficient synthesis of a wide range of organic compounds. |
Chemistry World November 27, 2008 Lewis Brindley |
Bryostatin Synthesis Made Simple US chemists have dramatically shortened the synthesis of byrostatin 16, one of a family of natural products that show promising activity against cancer but can't easily be extracted from nature or made artificially. |
Chemistry World November 27, 2009 Simon Hadlington |
A simple way to join an olefin to an arene Chemists in the US have developed a simple and effective way to carry out a key class of reaction in organic synthesis - the bolting an olefin to an aromatic ring. |
Chemistry World August 20, 2008 |
Gold's Magic Number A new gold catalyst developed by UK chemists can catalyse hydrocarbon oxidation, using O 2 as the only oxidant. But catalyst particle size is critical - above 2nm diameter, the catalyst loses all activity. |
Chemistry World April 6, 2009 Nina Notman |
Torn catalysts help polymers heal themselves Catalysts that are activated by a mechanical force tearing them in two have been designed by Dutch scientists. |
Chemistry World October 3, 2008 Lewis Brindley |
Nanotube catalysts improve industrial reaction A catalyst consisting of modified carbon nanotubes makes an important industrial reaction milder, safer and more selective, according to researchers in Germany. |
Chemistry World November 2010 |
Carbon Couplers Take the Prize Three giants of organic chemistry, who pioneered palladium-catalysed cross coupling reactions, have shared this year's Nobel prize. |
Chemistry World November 26, 2012 Laura Howes |
Protein coat prepares catalyst for cascades By protecting a transition metal catalyst with a protein coat, scientists have managed to couple up biocatalysts and chemical catalysts to perform a cascade reaction. |
Chemistry World April 4, 2008 James Mitchell Crow |
More to Catalysis Than Meets the Eye Catalysts are more than just a reactive surface. Changes beneath a metal's skin can completely change the course of a reaction. |
Chemistry World April 18, 2012 Elinor Richards |
Homogeneous Catalyst Recovery Made Easier Scientists have now found a way to recover homogeneous catalysts at the end of a chemical reaction that doesn't suffer from the slow reaction rates that affect current catalyst recovery systems. |
Chemistry World September 2011 Paul Docherty |
Column: Totally Synthetic Corey Stephenson of Boston University is an expert a type of reaction called photochemical reduction-oxidation. He has charmed photons into performing many chemical tricks, but one is a photoredox dehalogenation using blue light and a ruthenium bipyridyl catalyst. |
Chemistry World May 8, 2014 |
Mandelalide A The recent synthesis of the proposed structure of mandelalide A is a good example of a well-designed route that seamlessly integrates some cutting-edge chemistry. |
Chemistry World May 29, 2015 Derek Lowe |
Magic molecule modifiers The synthesis of a new organic molecule can be approached in several ways. |
Chemistry World August 11, 2010 Simon Hadlington |
Non-metal-catalysed C-C coupling Chinese chemists have successfully coupled aromatic molecules without the use of a transition metal catalyst - something that people have been trying to do for years with little success. |
Chemistry World February 20, 2008 Simon Hadlington |
Chemists Tame Acetaldehyde German chemists have prevented acetaldehyde from running amok during the Mannich reaction, opening up new avenues in drug discovery. |
Chemistry World November 1, 2007 Richard Van Noorden |
Step Change for Organic Synthesis US chemists discovered how to attack a complex molecule's unreactive carbon-hydrogen bonds, without resorting to wasteful synthetic aids like protecting and directing groups. |
Chemistry World September 20, 2007 Lewis Brindley |
New Catalyst Rings the Changes Organic chemists in the US have developed a method to control the stereochemistry of a useful intramolecular Diels-Alder reaction. |
Reactive Reports Issue 63 David Bradley |
Natural Copy Cat While plants convert carbon dioxide into sugar and oxygen, chemists are having a more difficult time finding an efficient method for converting carbon dioxide into useful fuels. |
Chemistry World October 21, 2012 Nina Notman |
Haber-Bosch power consumption slashed A new type of ruthenium catalyst could reduce the power consumption of ammonia production, claim Japanese scientists. |
Chemistry World December 17, 2009 Simon Hadlington |
Single catalyst gives two products from racemic mixture Chemists in the US have demonstrated a remarkable reaction in which a single catalyst can transform a racemic mixture - molecules identical in every way except for their chirality - into two distinct enantiomerically pure products. |
Chemistry World November 17, 2008 Simon Hadlington |
Catalyst flexes for extra control US chemists have developed a new type of catalyst capable of exerting high stereochemical control over olefin metathesis reactions |
Chemistry World November 12, 2008 Lewis Brindley |
Microscope Reveals Catalyst Secrets A promising technique for watching catalysts in action could provide new insights into how they work, report scientists in the Netherlands. |
Chemistry World December 2, 2008 James Mitchell Crow |
Just add air for cleaner carbon bonding UK scientists have found a new way to clip together organic molecules that could be the ultimate green approach to making carbon-carbon bonds |
Chemistry World April 2010 Paul Docherty |
Column: Totally Synthetic When one attempts the first synthesis of a natural product, the set of challenges are often unknown; which intermediates are either inaccessible or unstable, for instance. |
Chemistry World April 7, 2015 Hugh Cowley |
The Goldilocks of heterogeneous catalysis An international team of scientists has tethered palladium to a metal -- organic framework support using thiol groups normally associated with catalyst poisoning |
Chemistry World April 11, 2011 Mike Brown |
One catalyst, two reactions Researchers in the US have designed a novel material that can catalyse two separate, sequential reactions to produce industrially relevant intermediates in one pot. |
Chemistry World July 9, 2012 Phillip Broadwith |
'Molecular cobra' turns C-H to C=C A reagent developed by US chemists can selectively introduce synthetically useful C=C double bonds into unactivated carbon chains, guided by an activating group attached to a nearby oxygen or nitrogen atom. |
Chemistry World March 19, 2009 Manisha Lalloo |
Copper catalysts give meta aromatics UK Researchers have discovered that, simply by using a copper catalyst, they are able to perform tricky substitution reactions at a difficult position on benzene rings |