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Chemistry World
May 30, 2006
Michael Gross
A Physiological Role for Healthy Prions Researchers have shown that the healthy version of the scrapie pathogen helps maintain the optimum concentration of copper ions in the cell. mark for My Articles similar articles
Chemistry World
March 23, 2012
Michael Gross
Molecular chaperones caught on film Researchers have combined thousands of snapshots of the barrel-shaped protein GroEL to create a series of films that follow its movement and binding events. mark for My Articles similar articles
Chemistry World
January 19, 2011
Jon Cartwright
Modified protein binders give shortcut to drugs The method, which involves attaching polypeptides to the binders, could help reduce the work required to develop protein binders into safer drugs. mark for My Articles similar articles
Chemistry World
December 19, 2007
Simon Hadlington
Snapshot of Proteins Linked to Autism Researchers in France and the US have caught on camera the gentle embrace between two proteins that sit on either side of the junction between nerve cells. It's this short circuit that has thought to cause some types of autism. mark for My Articles similar articles
Chemistry World
March 6, 2007
Michael Gross
Nature's Supramolecular Chemistry Researchers studying a bacterial molybdenum-storage protein have teamed up with inorganic chemists to resolve the structure of the storage protein's central cavity. mark for My Articles similar articles
Chemistry World
December 12, 2011
Simon Hadlington
Zwitterion approach to stabilizing drug proteins Researchers in the US have discovered a new way to stabilize and protect protein molecules without affecting the protein's biological activity. mark for My Articles similar articles
Chemistry World
February 11, 2011
David Barden
Waking up to new possibilities in imaging UK researchers have used a cage-like molecule to smuggle metal ions into cells, which could improve medical imaging. mark for My Articles similar articles
Chemistry World
September 29, 2010
Hayley Birch
Protein folding: knotted or not A new study may help scientists unravel the complex problem of protein folding. The study suggests knotted proteins, which present a particular challenge to folding experts, could be untied with a couple of well-targeted tugs. mark for My Articles similar articles
Chemistry World
April 21, 2010
Simon Hadlington
Methane oxidising enzyme mystery solved The finding could lead to a cost-effective and environmentally clean method of methanol production for fuel and feedstock. mark for My Articles similar articles
Chemistry World
April 27, 2006
`Sticky Trees' Glue Molecules to Proteins Researchers have developed a chemical glue that binds molecules to proteins without compromising protein function. The method could be used to modify a wide range of proteins for a variety of purposes, such as in the development of new protein-based therapies. mark for My Articles similar articles
Chemistry World
February 7, 2011
Carl Saxton
Targeting memory loss A new treatment for Alzheimer's disease has been developed by Canadian and US scientists. mark for My Articles similar articles
Technology Research News
September 24, 2003
Artificial DNA stacks metal atoms In recent years, researchers have replaced some of DNA's natural bases with those that attach to metal atoms in order to coax DNA to organize metal ions into tiny structures. Researchers in Japan have tapped the method to form stacks of single metal ions. mark for My Articles similar articles
Chemistry World
October 24, 2013
Emily James
Parkinson's protein holds clue to oxidative stress Scientists from the UK have identified a possible cause for the oxidative stress found in patients with Parkinson's disease. mark for My Articles similar articles
Chemistry World
November 5, 2013
Emma Stoye
Copper signals warn bacteria of antibiotic assault Copper is known for its antimicrobial properties, but new research suggests that copper signalling within bacterial cells may also play an important role in antibiotic resistance. mark for My Articles similar articles
Chemistry World
October 16, 2006
Michael Gross
Brief Encounter Observing fleeting interactions between molecules in solution requires extremely sophisticated methods. NMR spectroscopists have now developed tools that let them watch the transient encounter between two proteins before a well-defined complex is formed. mark for My Articles similar articles
Chemistry World
May 9, 2007
James Mitchell Crow
Controlling prion folding US scientists report that prions, infamously linked to mad cow disease, have crucial subsections that control their behavior, including whether or not they can cross between species. mark for My Articles similar articles
Chemistry World
May 12, 2008
Simon Hadlington
'Super-yeast' tackles unnatural proteins Researchers in the US have engineered yeast cells to produce large amounts of proteins containing unnatural amino acids (UAAs) - a feat that has previously only been possible with bacteria. mark for My Articles similar articles
Chemistry World
May 26, 2011
Russell Johnson
Hunting elusive green fluorescent proteins After a 40 year hunt, scientists have tracked down the genes responsible for fluorescent proteins in Obelia medusa - a type of jellyfish. Knowledge of these genes could lead to new fluorescent protein tags for use in cell biology. mark for My Articles similar articles
Chemistry World
June 19, 2012
Anthony King
Nanoparticles linked to rheumatoid arthritis Three types of nanoparticles were found to ramp up protein citrullination in cell cultures, a change that can make the body think native proteins are foreign. This process has previously been linked to autoimmune disease. mark for My Articles similar articles
Chemistry World
April 23, 2009
Nina Notman
Metal toughens up spider silk Spider silk, already one of the strongest fibres known, can be made even stronger by infusing metals into its protein structure, scientists in Germany say. mark for My Articles similar articles
Chemistry World
October 9, 2011
Simon Hadlington
New probe throws light on cellular lipids Scientists in the US have developed a new sensor that can track and measure lipids in living cells. mark for My Articles similar articles
Chemistry World
August 24, 2009
Phillip Broadwith
'Chemical nose' sensor sniffs blood protein profile US scientists have developed a sensor system for profiling the protein content of human blood serum without needing individual receptors for each separate protein. mark for My Articles similar articles
Chemistry World
November 27, 2013
Jennifer Newton
A cytochrome from scratch Artificial proteins could be closer to participating in natural biochemical pathways after researchers show that bacteria will process amino acid sequences entirely unrelated to any natural protein to produce a fully functioning cytochrome. mark for My Articles similar articles
Chemistry World
June 14, 2011
A New Spin on Protein NMR A new technique will allow researchers to study protein structure in greater detail using NMR. mark for My Articles similar articles
Chemistry World
March 14, 2012
Helen Bache
Diabetes reduces antioxidant benefits Scientists in China have discovered that the blood plasma proteins of type II diabetes patients reduce the beneficial effects of dietary polyphenols. mark for My Articles similar articles
Chemistry World
November 23, 2009
Simon Hadlington
Non-protein antifreeze helps Arctic beetle chill out Scientists in the US have discovered a new class of biological antifreeze molecules - the first that do not contain proteins. mark for My Articles similar articles
Chemistry World
February 2012
Column: The crucible To understand the chemical choreography of the cell, we must acknowledge the bustling biomolecular ballroom in which it takes place, says Philip Ball mark for My Articles similar articles
Chemistry World
June 20, 2006
Jon Evans
Tuning Lanthanides to Detect Cancer Biomarkers Researchers have designed compounds containing lanthanide metal centers that detect a range of carbohydrates, glycolipids and phospholipids, including important disease biomarkers. mark for My Articles similar articles
Chemistry World
July 31, 2012
David Bradley
Hydrogels can release drugs one at a time A hydrogel that can be programmed to release different protein drugs one after the other rather than all at once could simplify the delivery of complex therapeutic regimens for various diseases. mark for My Articles similar articles
HHMI Bulletin
February 2011
Sarah C.P. Williams
Enforcing Order Changing the spatial arrangement of molecules in a cell can alter their functions. mark for My Articles similar articles
Chemistry World
October 2, 2012
Fiona McKenzie
Protein sorting within cells US scientists have used magnetic nanoparticles with specific ligands to latch on to and visualize specific proteins in living cells. mark for My Articles similar articles
Chemistry World
April 26, 2009
Simon Hadlington
Glowing protein in 'animal photosynthesis' Scientists have discovered that a glowing protein found in some exotic marine animals and used widely as a 'marker' in molecular biology has another remarkable property mark for My Articles similar articles
Chemistry World
July 15, 2010
Simon Hadlington
Synthetic enzyme catalyses Diels-Alder reaction The reaction is key to many organic syntheses and suggests that artificial enzymes could soon become part of the synthetic chemist's toolkit. mark for My Articles similar articles
Bio-IT World
June 12, 2002
Mark D. Uehling
Putting Proteins in Their Place Will a 'periodic table' of proteins help classify the ungainly beasts? mark for My Articles similar articles
Chemistry World
July 30, 2008
Sarah Houlton
A metal trap to stop Alzheimer's Trapping metals could prove a key to curing Alzheimer's disease, according to the promising results of early clinical trials on a compound called PBT2. mark for My Articles similar articles
Chemistry World
July 6, 2007
Michael Gross
Predicting How Proteins Fold Researchers in Italy and the UK have now developed a computational approach that can simulate the folding of membrane proteins in atomic detail. mark for My Articles similar articles
Chemistry World
October 27, 2014
Tim Wogan
Folding rules used to build unnatural proteins Scientists in the UK and US have designed and synthesized unnatural protein structures, using theoretical calculations to explore the factors affecting protein folding and stability. mark for My Articles similar articles
Chemistry World
November 2006
Philip Ball
Opinion: The Crucible Here are some of the latest instalments in the ongoing story of how protein misfolding causes neurodegenerative diseases -- a story that is not solely about developing clinical treatments or preventative medicines, but which goes to the heart of proteins' role as the stuff of life. mark for My Articles similar articles
Chemistry World
October 27, 2006
Richard Van Noorden
Synthetic Origami Folds Like Natural Enzymes Researchers have synthesised a large organic molecule that folds up like a small protein, though its backbone is entirely non-biological. The achievement is a step along the path to producing truly synthetic enzymes in the laboratory. mark for My Articles similar articles
Chemistry World
December 12, 2006
Michael Gross
Ancient Protein Moonlights in the Eye A structural protein in the mouse eye lens is the evolutionary descendant of an ancient bacterial enzyme, researchers have found -- suggesting that moonlighting saved the protein from oblivion when its original role was taken over by a different family of enzymes. mark for My Articles similar articles
Chemistry World
April 28, 2011
Laura Howes
Polymer collapses in a flash Researchers in the Netherlands have created a polymer that folds up like a protein on exposure to light. mark for My Articles similar articles
Chemistry World
September 1, 2006
Katharine Sanderson
Copper Mines and Coordination Chemistry Extracting pure copper metal from low-grade metal ores will benefit from the latest coordination chemistry research, thanks to a molecule that can hold negative and positive ions in place, UK chemists claim. mark for My Articles similar articles
Chemistry World
February 3, 2013
Andy Extance
Enzyme draws nanopore protein sequencing nearer US scientists at the University of California, Santa Cruz, have made a key step towards nanopore protein sequencing, thanks to an 'unfoldase' enzyme. Mark Akeson's team exploited this enzyme to unravel proteins and pull them through nanopores. mark for My Articles similar articles
Chemistry World
November 25, 2013
Carla Pegoraro
Steering cells towards biocomputers Bacterial toxins that undergo unique cell interactions have been used to perform logic functions by researchers in Germany. This innovation will help push the limits of synthetic biology. mark for My Articles similar articles
HHMI Bulletin
February 2011
Michele Solis
Right Before Your Eyes Coupling protein sequence to function, thousands of variants at a time. mark for My Articles similar articles
Chemistry World
February 3, 2010
Simon Hadlington
New 'hook' for reversibly binding molecules to proteins UK chemists have found a simple new 'hook' that allows molecules to be attached to proteins and later removed, something that is currently difficult to achieve. mark for My Articles similar articles
HHMI Bulletin
May 2010
Kendall Powell
Malaria's Weakness With different approaches, two HHMI researchers land on an enzyme critical to the malaria parasite's destructive ways. mark for My Articles similar articles
The Motley Fool
December 29, 2005
Stephen D. Simpson
Minds on the Mines: Copper Insatiable demand from China and the after-effects of years of under-investment in new capacity have launched the price of this base metal skyward. Investors, take note. mark for My Articles similar articles
Chemistry World
January 15, 2010
Kate McAlpine
Capturing carbon with copper A team of researchers in the Netherlands have devised a trap that can pull carbon dioxide out of the air. mark for My Articles similar articles
Chemistry World
July 21, 2011
Elinor Richards
Cell Control to Change Cell Function US scientists can now control the reactions occurring inside cells. mark for My Articles similar articles