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IEEE Spectrum March 2011 Lucks & Arkin |
Synthetic Biology's Hunt for the Genetic Transistor How genetic circuits will unlock the true potential of bioengineering |
Chemistry World October 20, 2008 Hayley Birch |
RNA computers built in yeast US scientists have assembled ribonucleic acids into an adaptable logic system that can be programmed to sense and respond to molecules inside living yeast cells. |
Chemistry World July 21, 2011 Elinor Richards |
Cell Control to Change Cell Function US scientists can now control the reactions occurring inside cells. |
HHMI Bulletin February 2011 Sarah C.P. Williams |
Enforcing Order Changing the spatial arrangement of molecules in a cell can alter their functions. |
Wired January 2005 Oliver Morton |
Life, Reinvented A group of MIT engineers wanted to model the biological world. But, damn, some of nature's designs were complicated! So they started rebuilding from the ground up - and gave birth to synthetic biology. |
Chemistry World May 12, 2008 Simon Hadlington |
'Super-yeast' tackles unnatural proteins Researchers in the US have engineered yeast cells to produce large amounts of proteins containing unnatural amino acids (UAAs) - a feat that has previously only been possible with bacteria. |
Chemistry World May 7, 2014 Emma Stoye |
Bacterium survives unnatural DNA transplant The first organism that can grow and replicate with an unnatural base pair in its DNA -- giving the cell six nucleotides instead of the usual four -- has been created by scientists in the US. |
Chemistry World May 10, 2013 Michael Parkin |
Super Glue for cells Scientists in Canada have made a super-strong cell membrane adhesive and used it to stick red blood cells together. The polymer, based on the phospholipid head group phosphatidyl choline, could be used to secure cells in particular positions for tissue engineering and wound closure. |
Scientific American June 2008 Melinda Wenner |
How Cells Make Use of Random Biochemical Reactions New studies reveal how cells exploit biochemical randomness. |
HHMI Bulletin February 2011 Sarah C.P. Williams |
Releasing the Brakes on Cell Fate Converting one cell type directly into another is a kind of modern-day alchemy, an ultimate goal in biological research. But unlike turning base metals into gold, changing a cell's identity is feasible, new research shows. |
Bio-IT World July 15, 2003 Julia Boguslavsky |
'Fingerprinting' a Single Cell Single-cell proteomics is finally within reach, thanks to a professor of analytical chemistry. |
Chemistry World June 27, 2010 Simon Hadlington |
Nanoparticles allow remote control of cells In an experiment reminiscent of the mind-control rays that featured prominently in B-movies from the 1950s, scientists in the US have used a magnetic field to alter the behavior of an animal. |
Chemistry World July 2008 Ananyo Bhattacharya |
Sparks of creation Chemists are at the forefront of synthetic biology, the burgeoning field that could soon create artificial life. |
Chemistry World May 20, 2010 Hayley Birch |
The first synthetic cell A chemically synthesised chromosome has for the first time been transplanted into a cell to produce a synthetic bacterium. |
Chemistry World May 17, 2007 Richard Van Noorden |
Bacterial Navigation Reprogrammed U.S. scientists have forced bacteria to follow new chemical signals by tweaking the bugs' natural guidance system. |
IEEE Spectrum May 2009 Neil Savage |
Engineers Evolve Transistors for Next-Gen Chips Evolutionary algorithms lead to new logic and memory that may smooth the way as CMOS nears its size limits |
Chemistry World February 2012 |
Column: The crucible To understand the chemical choreography of the cell, we must acknowledge the bustling biomolecular ballroom in which it takes place, says Philip Ball |
IEEE Spectrum August 2006 Schoenbach et al. |
Zap Extreme voltage could be a surprisingly delicate tool in the fight against cancer. The list of effects that scientists have achieved using nanoseconds-long pulses is growing rapidly, though their actual use as a medical treatment is still years away. |
Chemistry World March 10, 2011 Elinor Richards |
3D model to study breast cancer Scientists from the US have made a computational model of the formation of breast acini, the sac-like part of the milk-producing glands, to understand complex events occurring during the progression of breast cancer. |
Chemistry World February 17, 2012 Jon Cartwright |
DNA Nanorobots Seek and Destroy Disease Researchers have created a DNA-based nanorobot that can work its way through cell cultures, delivering cargo only at specific targets. |
Chemistry World July 18, 2014 Melissae Fellet |
Molecular computer calculates Ebola diagnosis A molecular computer could one day simplify analysis of biomedical assays like those used to diagnose Ebola, researchers say. |
Chemistry World October 31, 2012 Ian Le Guillou |
A cell for a cell If you ever need to isolate a single bacterial cell, why not build it a prison cell? This is the approach that colleagues from Sandia National Laboratories, US, have taken. Using multi-photon lithography, they can construct four walls and a roof around a single cell in just over a minute. |
Chemistry World April 19, 2011 Simon Hadlington |
Cell factories package drugs for delivery Scientists in Australia and Germany have used living cells as 'factories' to encapsulate particles such as drugs in biological membranes. |
Technology Research News October 8, 2003 Eric Smalley |
Magnetic memory makes logic Magnetic memory will soon put an end to the daily annoyance of waiting while your computer boots up from its hard disk. These chips that hold data when the power is off might also be capable of a lot more. Adding a few extra wires to each memory cell could turn the chips into efficient computer processors. |
Industrial Physicist Jennifer Ouellette |
Bioinformatics moves into the mainstream An explosion of data is being tamed with new systems |
Pharmaceutical Executive October 1, 2008 |
The other half of an HIV mystery is solved When HIV infects a human immune cell, which of the cell's own genes play a role? |
HHMI Bulletin Spring 2013 Nicole Kresge |
A Structural Toolbox Natalie Strynadka wants to design a better antibiotic. Her strategy: learn about the molecules bacteria use to invade cells. Her tool: structural biology. |
Chemistry World November 15, 2007 Tom Westgate |
Computing Goes Into Solution South Korean scientists have developed the first soluble molecular logic gates - one step along the way to designing molecular computers and biological lab-on-a-chip devices. |
The Motley Fool July 30, 2007 Brian Orelli |
Another Blow to Gene Therapy The FDA shuts down a clinical trial, tripping up Targeted Genetics and possibly its competitors. A subject in the trial of their gene therapy arthritis medication died shortly after taking the drug. |
HHMI Bulletin Winter 2013 Amber Dance |
A Trick of Light When miniSOG protein takes in blue light, it converts ordinary oxygen into a short-lived, excited state called singlet oxygen, which reacts with and changes the molecules around it. The singlet oxygen destroys the mitochondria's delicate machinery. |
Chemistry World October 31, 2010 Michael Gross |
Kiss of death for cancer cells Scientists have deciphered the surprising structure of the perforin pore, which delivers the 'kiss of death' to virus-infected cells and cancer cells in the body. |
Chemistry World August 12, 2011 Manisha Lalloo |
Unraveling cell membranes to understand drugs Researchers in Sweden have found a way to create flattened cell membranes, known as supported lipid bilayers, out of real cell structures. |
Scientific American July 3, 2006 Jeneen Interlandi |
An Immune Portal Protein may be a key to autoimmune disorders |
Chemistry World January 4, 2007 Henry Nicholls |
Microscopic Lab Investigates Contents of a Cell It's small-scale science that could have a massive impact on research into cell biology. Scientists have produced a microscopic laboratory where they can count individual proteins in a single cell. |
Chemistry World July 6, 2012 |
Protein power Tom Muir, professor of chemistry and molecular biology, Princeton University, US, is an expert in protein engineering and its application to studying cellular signalling networks. |
Chemistry World November 15, 2012 David Bradley |
DNA folds up into a synthetic ion channel An artificial ion channel that spans a synthetic lipid membrane has been created using DNA origami by researchers in Germany and the US. |
Chemistry World December 12, 2013 Jeanne Therese Andres |
Kiss-and-run drug delivery Carriers that release hydrophobic substances at cell membranes but do not enter the cells themselves could be the foundation for a new way to deliver drugs into cells, according to a team of scientists in Germany. |
Chemistry World December 18, 2012 Jennifer Newton |
Technique to measure chemotherapy effectiveness A technique to measure how effective chemotherapy is by studying the physical changes that occur in human cells has been developed by US scientists. |
HHMI Bulletin May 2010 Ivan Arnato |
Light Moves Light is becoming the tool of choice for researchers who want to precisely manipulate neurons and other cells. |
Bio-IT World July 2005 David M. Evans |
Cellular Imaging Takes Drug Discovery to New Heights The potential applications and ultimate value of high-content screening (HCS) and cellular image analysis are limited only by the imagination and expertise of the drug discovery groups using them to probe gene function and cell behavior. |
Bio-IT World July 2005 Kevin Davies |
Synthetic Biologists Assemble Codon Devices Company Emerging leaders in the new discipline of synthetic biology have raised $13 million in first-round venture funding for the field's first commercial entity - a startup company called Codon Devices. |
Chemistry World November 12, 2009 Hayley Birch |
New drug design looks top Notch against cancer A new type of drug that can block the switching on of certain genes in cancer cells has shown promise in mice. |
Technology Research News January 26, 2005 |
Magnetic Logic Becomes Practical Researchers from Stanford University have improved a way to program magnetic random access memory (MRAM) to carry out computations. |
Reason October 2001 Ronald Bailey |
Blastocyst Brouhaha Which human cells count as people? |
Chemistry World February 13, 2006 |
Nanoparticles Detect Cell Suicide Plans Researchers have developed a nanotechnological assay for detecting programmed cell death. The technique is effective in cell cultures, they report, and might eventually be used in humans. |
Chemistry World June 9, 2008 Simon Hadlington |
Artificial virus silences genes Scientists in Korea have created an artificial virus that can target the nucleus of cancer cells and knock out specific genes. |
Technology Research News August 27, 2003 Kimberly Patch |
DNA plays tic-tac-toe In addition to its natural role as the blueprint of life, DNA has been tapped to compute and to form nanoscale machines. A new type of DNA logic is aimed at marrying these artificial functions to make control circuits for nano machines. The first result is an unbeatable tic-tac-toe player. |
Chemistry World May 21, 2012 Simon Hadlington |
Rewritable DNA for digital data storage A rewritable memory storage module can form the basis of a digital memory system, scientists suggest, with the cell being able to 'record' transient changes in its internal chemistry. |
HHMI Bulletin February 2012 Sarah C.P. Williams |
The Twists and Turns of Immunity Fred Alt has built a career making sense of the immune system -- specifically, the diverse antibodies that fight off invading molecules, from viruses to cancer cells to pollen. |
Chemistry World April 2010 |
Column: The crucible We are getting better at manipulating cells to grow into the tissues we need. Chemical factors are key, says Philip Ball |