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Chemistry World September 23, 2008 Simon Hadlington |
Nanoparticles Hide Behind Protein Cloak Polymer nanoparticles suspended in human blood become cloaked in plasma proteins, new research has shown. |
Scientific American July 3, 2006 Jeneen Interlandi |
An Immune Portal Protein may be a key to autoimmune disorders |
Chemistry World April 6, 2010 Lewis Brindley |
Immune cells fight off nanotubes Carbon nanotubes can be degraded by an enzyme found in human immune cells, report US researchers. |
Chemistry World June 27, 2010 Simon Hadlington |
Nanoparticles allow remote control of cells In an experiment reminiscent of the mind-control rays that featured prominently in B-movies from the 1950s, scientists in the US have used a magnetic field to alter the behavior of an animal. |
Chemistry World March 9, 2009 Lewis Brindley |
Finding the Risks of Nanoparticle Exposure A new model for nanoparticle exposure should provide more realistic insights into the possible health risks of airborne nanoparticles, researchers in Switzerland claim. |
BusinessWeek March 14, 2005 Arnst & Barrett |
Another Ailing Miracle Drug Biogen's troubles with Tysabri are a setback for immune-system treatments |
Chemistry World June 13, 2007 James Mitchell Crow |
Renewed Therapeutic Promise for Arthritis Patients Three new treatments for rheumatoid arthritis, the most common chronic inflammatory joint disease in the industrialized world, offer hope to patients where existing drugs have failed. |
American Family Physician September 15, 2005 |
Rheumatoid Arthritis: What You Should Know A patient hand out on the condition, its diagnosis and treatment options. |
Chemistry World October 2, 2012 Fiona McKenzie |
Protein sorting within cells US scientists have used magnetic nanoparticles with specific ligands to latch on to and visualize specific proteins in living cells. |
Chemistry World December 3, 2013 Simon Hadlington |
Caged toxin for safer, better bacterial vaccines Researchers in the US have developed a new way of vaccinating against bacterial toxins by caging them in hybrid nanoparticles. |
Chemistry World August 24, 2009 Phillip Broadwith |
'Chemical nose' sensor sniffs blood protein profile US scientists have developed a sensor system for profiling the protein content of human blood serum without needing individual receptors for each separate protein. |
HHMI Bulletin Spring 2013 Sarah C.P. Williams |
Sounding the Alarm Details on how cells detect and respond to foreign DNA may provide clues to autoimmune diseases. |
Chemistry World October 24, 2008 Hayley Birch |
Proteins swap partners UK researchers have discovered that proteins which use metal cofactors can be surprisingly promiscuous metal binders, happily taking up the 'wrong' metal. |
Chemistry World November 7, 2010 Laura Howes |
Inhaled nanoparticles, from there to where? US scientists have for the first time shown how the size and surface properties of nanoparticles can affect where they end up in the body after they are inhaled. |
Chemistry World February 4, 2009 Matt Wilkinson |
GSK targets autoimmune biologics GSK recently signed seven drug development deals that could see the company release a suite of drugs to treat inflammatory diseases ranging from rheumatoid arthritis to lupus. |
Chemistry World October 7, 2010 Simon Hadlington |
New light shed on 'photothermal' cell death Photothermal therapy - where tiny particles of a metal are introduced into a cell and heated by laser light to kill the cell - might not work in the way people think, researchers in the UK have discovered. |
Science News November 24, 2001 Janet Raloff |
Decaf May Not Always Be Best Data from a pair of large studies reported in November at the American College of Rheumatology meeting in San Francisco now suggest that a woman's choice of morning coffee may affect her joints... |
The Motley Fool March 9, 2010 Brian Orelli |
The Opportunity That Wasn't Roche and Biogen Idec are suspending development of ocrelizumab for rheumatoid arthritis because patients are coming down with opportunistic infections. |
Chemistry World March 6, 2006 Jon Evans |
Nanoprobes Light up Cellular Demolition Researchers have developed a method for detecting and imaging programmed cell death (apoptosis). The method, involving polymer nanoparticles, could be used to diagnose apoptosis-related diseases and inform drug development. |
Chemistry World December 19, 2007 Simon Hadlington |
Snapshot of Proteins Linked to Autism Researchers in France and the US have caught on camera the gentle embrace between two proteins that sit on either side of the junction between nerve cells. It's this short circuit that has thought to cause some types of autism. |
The Motley Fool October 8, 2010 Brian Orelli |
Pfizer's Rash (of Bad News) Is Over Data from Pfizer's phase 2 trial testing tasocitinib against psoriasis, a painful autoimmune skin disease, looks promising even given its small size. |
Chemistry World May 12, 2008 Simon Hadlington |
'Super-yeast' tackles unnatural proteins Researchers in the US have engineered yeast cells to produce large amounts of proteins containing unnatural amino acids (UAAs) - a feat that has previously only been possible with bacteria. |
Reactive Reports September 2005 David Bradley |
When Good Turns Bad Prions, the protein-like pathogens at the heart of the fatal brain disorder CJD, so-called mad cow disease, and related diseases can rapidly "remodel" good proteins into bad, according to US scientists, who have demonstrated this for the first time in living cells. |
Chemistry World December 9, 2013 James Urquhart |
Drug fix for misfolded proteins promises hope for incurable diseases Researchers have been looking into pharmacological chaperones or pharmacoperones. They might treat diseases brought about by genetic mutations that cause otherwise functional proteins to become misfolded or misrouted. |
Chemistry World November 2006 Philip Ball |
Opinion: The Crucible Here are some of the latest instalments in the ongoing story of how protein misfolding causes neurodegenerative diseases -- a story that is not solely about developing clinical treatments or preventative medicines, but which goes to the heart of proteins' role as the stuff of life. |
Chemistry World August 24, 2006 Jessica Ebert |
Alzheimer's Researchers Tackle Waste Disposal The memory of mice with Alzheimer's-like symptoms is improved by inoculating the mice with an enzyme involved in protein degradation, report US researchers. The work could lead to new therapies for patients with Alzheimer's disease. |
Chemistry World July 26, 2010 Phillip Broadwith |
Predicting nanoparticle toxicity Judging nanoparticle toxicity could be made easier by a new theoretical model that predicts which materials will make nanoparticles that could damage living cells. The model can predict the available electronic energy levels in the nanoparticle structure |
Chemistry World July 29, 2014 Vijay Shankar |
Nanoparticle protects protein drug cargo A team of researchers at Brigham and Women's Hospital, Boston, US has developed novel nanoparticles that could deliver protein drugs to where they are needed unscathed. |
Chemistry World April 9, 2015 |
Big problems with little particles? There is a risk that poor toxicology studies could start undermining the success of nanomaterials. |
Chemistry World October 27, 2014 Tim Wogan |
Folding rules used to build unnatural proteins Scientists in the UK and US have designed and synthesized unnatural protein structures, using theoretical calculations to explore the factors affecting protein folding and stability. |
American Family Physician September 15, 2005 Rindfleisch & Muller |
Diagnosis and Management of Rheumatoid Arthritis Rheumatoid arthritis is the most common inflammatory arthritis, affecting 0.8 percent of the adult population worldwide. It is a lifelong disease, although patients can go into remission. Physicians must be aware of common comorbidities. |
Scientific American January 2, 2006 JR Minkel |
T Cells for Brain Cells Some researchers claim that inducing a mild autoimmune reaction could actually protect the central nervous system from a spectrum of neurodegenerative conditions, from glaucoma and spinal cord injury to Parkinson's and Alzheimer's disease. |
Chemistry World April 7, 2009 Lewis Brindley |
Cells get in line Magnetic nanoparticles that 'shepherd' cells into neat lines have been designed by American scientists. |
Popular Mechanics June 23, 2008 Jancy Langley |
Amid Food Scares, Nanotech Offers Healthier Option for Livestock Scientists may have found a safer alternative to antibiotic-laden food sources just five years away from America's farms. |
Chemistry World April 11, 2006 Jon Evans |
Nanotechnology Tackles Chemotherapy Chemists and medical researchers have developed nanoparticles that target chemotherapy drugs directly at tumours. The researchers claim that the same technique could be used to develop nanoparticle-based treatments for a wide range of other diseases. |
The Motley Fool August 31, 2011 Brian Orelli |
Antibodies: They're Not Just for Fighting Infection Anymore Therapeutic antibodies have continued to evolve since the first, OKT3, was approved back in 1986. Biotech investors had better pay attention, lest the technology passes them by. |
Chemistry World May 13, 2009 Lewis Brindley |
Combination nanoparticles to fight cancer Korean chemists have assembled a multitalented nanoparticle that can hunt down, treat, and illuminate cancerous cells. |
IEEE Spectrum September 2007 Karn & Matthews |
Nano Particles Without Macroproblems Quick and dirty advice for keeping nanotech clean. |
BusinessWeek May 24, 2004 Arlene Weintraub |
Regenerative Medicine's Slow Start Scientists think proteins that spur the body to heal could make powerful drugs, but harnessing that potential has been tough |
Chemistry World June 27, 2012 Helen Bache |
Schizophrenia: a disease of the brain? Scientists in China have unearthed further evidence that a malfunction of the immune system contributes to the development of schizophrenia. |
Chemistry World May 31, 2006 Jon Evans |
Carbon Joins the Dots Carbon could soon replace cadmium as the material of choice for quantum dots, following the development of fluorescent carbon nanoparticles by scientists. |
Chemistry World September 25, 2009 Simon Hadlington |
New MRI protein probe Researchers in Japan have invented a new way to detect the presence of proteins in cells and tissues by magnetic resonance imaging. |
Chemistry World February 12, 2012 Jon Cartwright |
Nanoparticles slow iron absorption in the gut Nanoparticles used in food and pharmaceuticals could have unintended physiological effects. |
Chemistry World January 21, 2011 Jennifer Newton |
Early lung cancer diagnosis Patients with lung cancer have elevated levels of a specific protein in their blood that could be used as a biomarker for the disease, say scientists from South Korea. |
Pharmaceutical Executive July 30, 2007 |
Tomorrow's Drugs A look at the seven top therapies and technologies vying to deliver the next generation of drugs. |
Wired September 2002 Amanda Griscom |
Take These Genes and Call Me in the Morning Gene vaccines may be relatively new, but they're the logical outgrowth of two familiar strands of medical science. |
Chemistry World February 18, 2008 John Bonner |
Flicking the Acetyl Switch A strain of Escherichia coli that can produce proteins containing an acetylated version of the amino acid lysine could help to reveal how acetylation changes the function of hundreds of proteins inside cells. |
Chemistry World June 25, 2013 Michael Gross |
A foaming protein from the horse's mouth Researchers in the UK have solved the structure of this protein, yielding tantalizing hints to a novel kind of surface activity and to evolutionary connections to other examples. |
Pharmaceutical Executive August 1, 2005 |
Making Drugs Smarter An interview with Nicholas Peppas on how the world of drug delivery -- at least at its cutting edges -- has begun to converge with diagnostics, tissue design, and materials science in ways that promise to transform some areas of medicine. |
Chemistry World February 19, 2009 Nina Notman |
Nanoparticles give cancer drug a boost US scientists have taken a novel step towards fighting the reoccurrence of lung cancer, using drug delivering nanoparticles. |