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Chemistry World June 14, 2011 |
A New Spin on Protein NMR A new technique will allow researchers to study protein structure in greater detail using NMR. |
Bio-IT World May 2006 Robert M. Frederickson |
A New (Bio)Spin on NMR Applications Bruker BioSpin recently announced several introductions to improve throughput, sensitivity, and versatility of its systems for nuclear magnetic resonance applications starting with the SampleJet, a robotics system for high-throughput transfers of NMR sample tubes into the NMR spectrometer. |
Chemistry World November 23, 2006 Simon Hadlington |
Unfolding Peptide Watched in Real Time Researchers have observed a peptide molecule changing shape in real time. The ultrafast process was monitored using a technique called transient two-dimensional infrared spectroscopy. |
Chemistry World August 17, 2011 Jon Cartwright |
Plasma Treatment to Use Patient's Proteins to Improve Medical Device Biocompatibility Researchers have developed a plasma treatment that can make any medical device biocompatible by sticking a patient's own proteins to it. |
Chemistry World June 6, 2010 Philip Ball |
Blood-like liquid protein formed A liquid form of the oxygen-binding protein myoglobin retains its biological function even though it seems virtually water-free, researchers have found. |
Chemistry World December 12, 2011 Simon Hadlington |
Zwitterion approach to stabilizing drug proteins Researchers in the US have discovered a new way to stabilize and protect protein molecules without affecting the protein's biological activity. |
Chemistry World December 19, 2007 Simon Hadlington |
Snapshot of Proteins Linked to Autism Researchers in France and the US have caught on camera the gentle embrace between two proteins that sit on either side of the junction between nerve cells. It's this short circuit that has thought to cause some types of autism. |
Chemistry World October 24, 2008 Hayley Birch |
Proteins swap partners UK researchers have discovered that proteins which use metal cofactors can be surprisingly promiscuous metal binders, happily taking up the 'wrong' metal. |
Reactive Reports Issue 51 David Bradley |
Protein Crystals Trapped Researchers have developed a new technique for crystallizing proteins, which could open up a whole range of materials to this powerful analytical technique. |
HHMI Bulletin Spring 2013 Nicole Kresge |
A Structural Toolbox Natalie Strynadka wants to design a better antibiotic. Her strategy: learn about the molecules bacteria use to invade cells. Her tool: structural biology. |
Wired January 18, 2008 Miyoko Ohtake |
Fighting the Most Lethal Diseases With 3-D Snapshots of Their Pathogens If you can get a good look at the proteins, you can find places where other molecules can latch on and exterminate the bugs. |
Chemistry World August 26, 2008 Fred Campbell |
High-throughput protein microarrays on the way A new method to rapidly generate protein microarrays has been developed by UK researchers at the University of Manchester. |
HHMI Bulletin Winter 2013 Nicole Kresge |
A Structural Revolution Over the years, scientists and artists have used an assortment of techniques to showcase molecular structure. |
Chemistry World August 1, 2010 Mike Brown |
Snapshots of mystery molecular structures Researchers have used atomic force microscopy to produce clear molecular images that can help determine the correct atomic structure of unknown organic molecules. |
Reactive Reports Issue 52 David Bradley |
Interview with Gary Martin With more than 35 years experience in NMR spectroscopy, Gary Martin reveals some of the insights he has gained in this field. |
Industrial Physicist Aug/Sep 2003 Ineke Malsch |
Protein research calls for advanced instruments The science of protein interactions is becoming a major tool in biomedical and drug development research. Carrying out and advancing such studies more efficiently and effectively, however, will require new, cutting-edge instrumentation. |
Chemistry World February 2, 2012 Philip Robinson |
Ultrafast NMR shows the way Chemists have created an ultrafast NMR technique that can 'watch' how chemical reactions occur in real time. They've used the technique to follow the formation of pyrimidines from carbonyls and even identified new intermediates never before thought to be part of the reaction. |
Chemistry World November 6, 2015 Emma Stoye |
Eye drops show promise treating cataracts and even reversing damage A molecule that can bind and re-solubilize misfolded proteins in the eye has been identified by researchers in the US. |
Chemistry World September 24, 2007 Simon Hadlington |
Viral Nanoreactor Captures Single Molecules Researchers in the Netherlands have created a biochemical nanoreactor by cracking open a virus, removing its contents then reassembling the virus's protein coat around a single molecule of enzyme. |
Chemistry World August 24, 2009 Phillip Broadwith |
'Chemical nose' sensor sniffs blood protein profile US scientists have developed a sensor system for profiling the protein content of human blood serum without needing individual receptors for each separate protein. |
Chemistry World April 30, 2007 Victoria Gill |
Amyloid Protein Seen to Zip Together Amyloid proteins' long, complicated structure makes them tricky to study, but U.S. researchers have found that they share a common feature that could provide a drug target for an array of incurable conditions. |
Chemistry World October 26, 2007 Richard Van Noorden |
Proton NMR Spots Shape-Shifting Tablets UK scientists have extended the bounds of solid-state NMR to quickly solve a problem plaguing the pharmaceutical industry: how to spot unwanted crystal packing forms in a drug tablet. |
Prepared Foods February 2008 Sharon Book |
Article: Protein Ingredients for Health and Texture A variety of soy, dairy and egg proteins are available for the food formulator to obtain the desired texture in a food or beverage. |
Chemistry World December 5, 2007 Ananyo Bhattacharya |
Structural Snapshot Shows Monster Protein A structural snapshot of a protein capsule has revealed details of the largest cellular component ever imaged by x-ray crystallography. |
HHMI Bulletin February 2011 Michele Solis |
Right Before Your Eyes Coupling protein sequence to function, thousands of variants at a time. |
Chemistry World February 13, 2014 Philip Ball |
Ice core to antifreeze protein's inner workings The antifreeze protein that protects the winter flounder from sub-zero temperatures has been found to have an odd structure. |
Chemistry World June 2009 Michael Gross |
Bubble-wrapped frogs Tropical frogs create remarkable protein foams to protect their spawn. Exploration of the underlying chemistry has only just begun |
Bio-IT World June 12, 2002 Mark D. Uehling |
Putting Proteins in Their Place Will a 'periodic table' of proteins help classify the ungainly beasts? |
Chemistry World June 25, 2013 Michael Gross |
A foaming protein from the horse's mouth Researchers in the UK have solved the structure of this protein, yielding tantalizing hints to a novel kind of surface activity and to evolutionary connections to other examples. |
Chemistry World January 9, 2013 Laura Howes |
Antifreeze protein's watery dance Most animals left in -30 C temperatures wouldn't last very long. Not only would they get hypothermia, but the water in their bodies would start to freeze. Some animals and plants, however, use antifreeze proteins to keep ice at bay. |
Chemistry World April 4, 2013 Phillip Broadwith |
A solution to fluoronium riddle The first evidence for hypervalent fluorine cations, or fluoronium ions, in solution has been found by US chemists. |
Technology Research News June 18, 2003 |
Protein traps nanoparticles Researchers from the University of Tokyo in Japan have adapted a tubular bacterial protein for technological applications by coaxing it to combine with individual luminescent semiconductor nanoparticles. |
Chemistry World June 12, 2013 Kirsty Muirhead |
An end to chasing molecules that were never there? Ariel Sarotti from the Rosario National University, Argentina, has developed a new, computationally inexpensive method combining calculated and experimental 13C NMR data to flag up incorrect structures. |
Chemistry World September 25, 2009 Simon Hadlington |
New MRI protein probe Researchers in Japan have invented a new way to detect the presence of proteins in cells and tissues by magnetic resonance imaging. |
Chemistry World February 27, 2009 Hayley Birch |
More data from mixtures via NMR Finnish scientists have developed a new technique for separating out the NMR spectra of compounds in a mixture. |
Chemistry World June 23, 2015 Derek Lowe |
Missing the target There are enzymes that no mustard has ever cut, to steal a phrase from science fiction author James Blish. Phosphatases, the flip side of kinase activity, are a perfect example. |
Chemistry World July 20, 2009 Philip Ball |
Researchers form first liquid protein Chemists at the University of Bristol, UK and their colleagues, in collaboration with the Max Planck Institute for Colloid and Interface Research in Golm, Germany, have figured out how to convert pure proteins into a liquid state, without any solvent. |
Chemistry World February 3, 2013 Andy Extance |
Enzyme draws nanopore protein sequencing nearer US scientists at the University of California, Santa Cruz, have made a key step towards nanopore protein sequencing, thanks to an 'unfoldase' enzyme. Mark Akeson's team exploited this enzyme to unravel proteins and pull them through nanopores. |
Chemistry World October 2, 2012 Fiona McKenzie |
Protein sorting within cells US scientists have used magnetic nanoparticles with specific ligands to latch on to and visualize specific proteins in living cells. |
Technology Research News September 24, 2003 Kimberly Patch |
Heated plastic holds proteins One important task for biochips is sorting proteins, but it's tricky business getting protein molecules to be where you want them and stay away from where you don't. A tiny, plastic-coated hot plate allows scientists to trap and release proteins on command. |
Chemistry World July 26, 2012 Cecilia Fenech |
Understanding 2D NMR Organic structure determination using 2-D NMR spectroscopy: a problem-based approach by Jeffrey Simpson is a balanced text covering both theoretical and practical aspects of NMR spectroscopy. |
Bio-IT World October 10, 2003 Jeffrey Skolnick |
Protein Structure Prediction in Drug Discovery Indications are that structure prediction can assist in the automated assignment of proteins to known pathways. |
Chemistry World January 30, 2013 Philip Robinson |
NMR with a light touch Interactions between NMR-active nuclei in a sample and laser light could lead to a new, simpler form of NMR. |
Wired April 2001 David Ewing Duncan |
The Protein Hunters Step One: Crack the genome. Step Two: Unlock the molecular structure of amino acids. Step Three: Get ready for the robo-fast, custom-drug future... |
Chemistry World October 8, 2008 Sarah Houlton |
Artificial protein chemistry licensed to industry UK researchers are licensing to industry their method of making artificial proteins by chemically modifying individual amino acid structures. |
Chemistry World October 27, 2014 Tim Wogan |
Folding rules used to build unnatural proteins Scientists in the UK and US have designed and synthesized unnatural protein structures, using theoretical calculations to explore the factors affecting protein folding and stability. |
Chemistry World July 2007 Dylan Stiles |
Opinion: Bench Monkey Synthesizing molecules that force atoms into bizarre contortionist acts is the only way to learn. |
Bio-IT World September 11, 2003 Mark D. Uehling |
Fishing Chips The next generation of protein microarrays from the likes of Protometrix and Molecular Staging may threaten the early leads of Biacore and Ciphergen -- and work so well that drug companies won't want them. |
Science News October 14, 2006 Ivars Peterson |
Knots in Proteins Knotted proteins are rare, but more than just random occurrences. The secret of spontaneous knotting lies in the mathematics of self-avoiding random walks. |
Chemistry World May 17, 2012 David Bradley |
Plutonium in a Spin Spectroscopists have finally pinned down the nuclear magnetic resonance spectrum of plutonium-239. The finding might point the way to improved approaches to the long-term storage of nuclear waste. |