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Chemistry World February 18, 2008 John Bonner	Flicking the Acetyl Switch A strain of Escherichia coli that can produce proteins containing an acetylated version of the amino acid lysine could help to reveal how acetylation changes the function of hundreds of proteins inside cells.
Chemistry World August 17, 2011 Josh Howgego	Worms Modified to Express Unnatural Amino Acids Unnatural amino acids have been expressed for the first time in complex multicellular organisms. Researchers hope this will open up new ways to track biochemical processes and disease pathways.
Reactive Reports May 2007 David Bradley	A Scent for Explosives A new type of biosensor based on yeast, jellyfish proteins, and a rat's sense of smell could sniff out explosives, landmines, and agents, such as sarin gas, according to researchers.
Chemistry World August 2, 2011 Phillip Broadwith	Protein synthesis hijacked to turn out cyclic peptides Japanese researchers have developed a way of reprogramming the genetic code and using bacteria to make and screen huge libraries of cyclic peptides using unnatural amino acids.
HHMI Bulletin Fall 2012 Ingfei Chen	Same But Not Equal A code within the genetic code explains why identical proteins are produced at varying speeds.
IEEE Spectrum March 2011 Lucks & Arkin	Synthetic Biology's Hunt for the Genetic Transistor How genetic circuits will unlock the true potential of bioengineering
Chemistry World October 2, 2012 Fiona McKenzie	Protein sorting within cells US scientists have used magnetic nanoparticles with specific ligands to latch on to and visualize specific proteins in living cells.
Chemistry World October 27, 2014 Tim Wogan	Folding rules used to build unnatural proteins Scientists in the UK and US have designed and synthesized unnatural protein structures, using theoretical calculations to explore the factors affecting protein folding and stability.
Scientific American January 2006 Charles Q. Choi	Un-Killing the Messenger Processing bodies do more than serve as RNA trash bins in cells. Research now suggests that these P-bodies are less like junkyards and more like office centers, where messages are amassed, silenced and reactivated.
Chemistry World November 27, 2013 Jennifer Newton	A cytochrome from scratch Artificial proteins could be closer to participating in natural biochemical pathways after researchers show that bacteria will process amino acid sequences entirely unrelated to any natural protein to produce a fully functioning cytochrome.
Chemistry World November 13, 2014 Katrina Kramer	Persuading proteins to form porous polyhedra Researchers in the US have designed a hollow cube out of naturally occurring proteins, something that was previously only possible with DNA.
Pharmaceutical Executive November 1, 2006	Thoughtleader: Making Things Stick Ambrx has created the "glue" that allows researchers to attach activity-enhancing molecules to amino acids where they couldn't before.
HHMI Bulletin May 2010 Richard Saltus	A Silver Lining Sure, some prions can cause diseases, but others are turning out to be beneficial.
Chemistry World December 21, 2006 Henry Nicholls	Silent SNPs Serve up a Structural Surprise The sequence of amino acids no longer dictates the structure and function of a protein according to a surprising new paper.
Chemistry World March 21, 2013 Phillip Broadwith	AstraZeneca partners with Moderna for $240 million Moderna has developed a way to use messenger RNA (mRNA), the molecule cells use to turn DNA into proteins, to stimulate the production of specific proteins in cells where disease has diminished or eliminated their ability to do so.
Bio-IT World January 12, 2004 Pauline Parry	The Code Breakers Ambrx tinkers with the building blocks of life
Chemistry World March 30, 2011 Hayley Birch	Amino acid synthesis hints at how the genetic code expanded The detailed pathway for the biosynthesis of pyrrolysine - the 22nd and latest amino acid to be discovered - has been outlined by US researchers.
Chemistry World May 17, 2007 Richard Van Noorden	Bacterial Navigation Reprogrammed U.S. scientists have forced bacteria to follow new chemical signals by tweaking the bugs' natural guidance system.
Chemistry World July 21, 2011 Elinor Richards	Cell Control to Change Cell Function US scientists can now control the reactions occurring inside cells.
Chemistry World July 2008 Ananyo Bhattacharya	Sparks of creation Chemists are at the forefront of synthetic biology, the burgeoning field that could soon create artificial life.
Chemistry World May 7, 2014 Emma Stoye	Bacterium survives unnatural DNA transplant The first organism that can grow and replicate with an unnatural base pair in its DNA -- giving the cell six nucleotides instead of the usual four -- has been created by scientists in the US.
Chemistry World August 2, 2011 Kate McAlpine	Hacking into chemical cell phone calls US researchers have made a nanodevice that can eavesdrop on a cell's mutterings, and they say it could be adapted to listen in on conversations between cells.
Chemistry World October 20, 2008 Hayley Birch	RNA computers built in yeast US scientists have assembled ribonucleic acids into an adaptable logic system that can be programmed to sense and respond to molecules inside living yeast cells.
Chemistry World November 25, 2013 Carla Pegoraro	Steering cells towards biocomputers Bacterial toxins that undergo unique cell interactions have been used to perform logic functions by researchers in Germany. This innovation will help push the limits of synthetic biology.
Chemistry World October 8, 2008 Sarah Houlton	Artificial protein chemistry licensed to industry UK researchers are licensing to industry their method of making artificial proteins by chemically modifying individual amino acid structures.
Scientific American November 2007 Ed Regis	The Forgotten Code Cracker In the 1960s Marshall W. Nirenberg deciphered the genetic code, the combination of the A, T, G and C nucleotides that specify amino acids. So why do people think that Francis Crick did it?
Chemistry World May 26, 2011 Russell Johnson	Hunting elusive green fluorescent proteins After a 40 year hunt, scientists have tracked down the genes responsible for fluorescent proteins in Obelia medusa - a type of jellyfish. Knowledge of these genes could lead to new fluorescent protein tags for use in cell biology.
Chemistry World April 26, 2009 Simon Hadlington	Glowing protein in 'animal photosynthesis' Scientists have discovered that a glowing protein found in some exotic marine animals and used widely as a 'marker' in molecular biology has another remarkable property
Chemistry World October 1, 2008 Hayley Birch	Chemical Knockout for Chlamydia US scientists have used chemical inhibitors to block proteins that Chlamydia produces as it invades cells.
Chemistry World June 1, 2009 Phillip Broadwith	Wider therapeutic possibilities for botulinum toxin Change to a single amino acid in botulinum toxin A causes it to target non-neuronal signalling proteins, potentially widening the product's therapeutic applications
Chemistry World May 30, 2006 Michael Gross	A Physiological Role for Healthy Prions Researchers have shown that the healthy version of the scrapie pathogen helps maintain the optimum concentration of copper ions in the cell.
Chemistry World February 28, 2013 Andy Extance	Chemical transport defines 'Goldilocks' cell size A US team has suggested molecular movement as an answer to the question of why cells are the size they are. A question that they say 'still awaits an answer from first principles'.
HHMI Bulletin February 2011 Michele Solis	Right Before Your Eyes Coupling protein sequence to function, thousands of variants at a time.
Reactive Reports October 2006 David Bradley	RNA Chemistry Zips Up Nobel Prize If Watson and Crick unlocked the mystery of DNA's structure, then Stanford University's Roger Kornberg and his team unzipped the secret of how the cell converts DNA into the RNA needed to make proteins.
Chemistry World March 29, 2009 Lewis Brindley	Gene gels pump out proteins Gels made with genes incorporated into the structure could soon make protein production cheaper and easier, according to researchers in the US.
Chemistry World July 15, 2010 Simon Hadlington	Synthetic enzyme catalyses Diels-Alder reaction The reaction is key to many organic syntheses and suggests that artificial enzymes could soon become part of the synthetic chemist's toolkit.
Chemistry World October 12, 2015 Andy Extance	'Chemical search engine' backs alternative route to life A key class of biological molecules neglected in the search for life's chemical origins could have appeared spontaneously before organisms, UK scientists say.
Chemistry World June 17, 2013 Eleanor Merritt	Switching chirality in amino acids An international team of scientists has developed a purely chemical approach to interconvert L- and D-amino acids. This method could rival enzymatic routes used in industry, and enable cheaper production of some pharmaceuticals.
Chemistry World March 3, 2009 Lewis Brindley	Sweet-toothed bacteria make their own vaccine With careful feeding, bacteria can produce vaccines against themselves, scientists in the US and China have found.
Scientific American June 2008 Melinda Wenner	How Cells Make Use of Random Biochemical Reactions New studies reveal how cells exploit biochemical randomness.
Chemistry World June 9, 2008 Simon Hadlington	Artificial virus silences genes Scientists in Korea have created an artificial virus that can target the nucleus of cancer cells and knock out specific genes.
Chemistry World June 13, 2011 Laura Howes	Cells turned into living lasers with fluorescent protein With a little help from a fluorescent protein, mammalian cells have been transformed into living lasers. This discovery could help improve imaging of living cells, enabling researchers to explore what's going on inside.
Chemistry World January 4, 2007 Henry Nicholls	Microscopic Lab Investigates Contents of a Cell It's small-scale science that could have a massive impact on research into cell biology. Scientists have produced a microscopic laboratory where they can count individual proteins in a single cell.
Chemistry World October 4, 2009 Simon Hadlington	More sex and grapefruit to keep you young? Scientists have shown that feeding a simple polyamine called spermidine to worms, fruit flies and yeast significantly prolongs their lifespan.
Chemistry World October 31, 2010 Michael Gross	Kiss of death for cancer cells Scientists have deciphered the surprising structure of the perforin pore, which delivers the 'kiss of death' to virus-infected cells and cancer cells in the body.
Chemistry World March 1, 2010 Andy Extance	Bacterial mix sweetens biodrug synthesis Bacteria welcome in the human gut are set to become better factories for biological drugs thanks to modified genes from another, gastroenteritis-causing, species.
Chemistry World March 27, 2014 James Urquhart	Synthetic yeast chromosome is fully functional The first complete and functional synthetic yeast chromosome has been created by a team of scientists based in the US.
Chemistry World November 25, 2009 Simon Hadlington	Virus shells traps multiple proteins Scientists in The Netherlands have devised a way to pack large numbers of proteins into the empty shell of a virus.
Chemistry World May 15, 2014	It's life, but not as we know it A US team at The Scripps Research Institute in California, has unveiled the first living Escherichia coli cells with non-natural base pairs in their DNA.
Chemistry World May 5, 2011 Simon Hadlington	Revolutionary new single-cell labelling method Researchers in the US and Canada have combined mass spectrometry with a technique called flow cytometry to follow dozens of biochemical markers on individual cells simultaneously.