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Chemistry World August 14, 2008 Jane Qiu |
Gel Releases Drugs on Cue A novel gel that delivers drugs in response to a chemical cue may help to make insulin jabs a thing of the past. |
Chemistry World January 19, 2011 Jon Cartwright |
Modified protein binders give shortcut to drugs The method, which involves attaching polypeptides to the binders, could help reduce the work required to develop protein binders into safer drugs. |
Technology Research News March 24, 2004 |
DNA has nano building in hand Researchers from Ludwig Maximilians University in Germany have built a simple molecular machine from DNA that can bind to and release single molecules of a specific type of protein. |
Chemistry World October 8, 2012 Emma Shiells |
Medicinal hope for injectable hydrogels Doo Sung Lee and colleagues from Sungkyunkwan University developed an amphoteric copolymer to form dually cationic and anionic hydrogels, in response to pH and temperature changes. |
Chemistry World December 12, 2011 Simon Hadlington |
Zwitterion approach to stabilizing drug proteins Researchers in the US have discovered a new way to stabilize and protect protein molecules without affecting the protein's biological activity. |
Chemistry World April 27, 2006 |
`Sticky Trees' Glue Molecules to Proteins Researchers have developed a chemical glue that binds molecules to proteins without compromising protein function. The method could be used to modify a wide range of proteins for a variety of purposes, such as in the development of new protein-based therapies. |
Chemistry World January 22, 2010 Lewis Brindley |
Gel turns clear for cocaine detection Chinese researchers have developed an aptamer cross-linked hydrogel that changes from bright red or blue to colourless when exposed to tiny amounts of cocaine. |
Chemistry World July 29, 2014 Vijay Shankar |
Nanoparticle protects protein drug cargo A team of researchers at Brigham and Women's Hospital, Boston, US has developed novel nanoparticles that could deliver protein drugs to where they are needed unscathed. |
Chemistry World February 3, 2013 Andy Extance |
Enzyme draws nanopore protein sequencing nearer US scientists at the University of California, Santa Cruz, have made a key step towards nanopore protein sequencing, thanks to an 'unfoldase' enzyme. Mark Akeson's team exploited this enzyme to unravel proteins and pull them through nanopores. |
Chemistry World June 1, 2012 Simon Hadlington |
Protein architecture with atomic precision Researchers have made a key breakthrough in designing and building geometrically defined nanostructures from proteins with unprecedented accuracy. |
Technology Research News January 14, 2004 |
Wet biochip preserves proteins Researchers from Kyushu University in Japan have produced a hydrogel material that makes it possible for proteins to survive aboard labs-on-a-chip. |
Chemistry World July 28, 2009 Michael Gross |
DNA to direct and switch off chemo Researchers in the US have developed a new approach to cancer chemotherapy using short DNA strands to help target delivery of the drug directly to cancer cells, and 'call it off' should problems arise. |
Chemistry World April 11, 2006 Jon Evans |
Nanotechnology Tackles Chemotherapy Chemists and medical researchers have developed nanoparticles that target chemotherapy drugs directly at tumours. The researchers claim that the same technique could be used to develop nanoparticle-based treatments for a wide range of other diseases. |
Chemistry World June 23, 2015 Derek Lowe |
Missing the target There are enzymes that no mustard has ever cut, to steal a phrase from science fiction author James Blish. Phosphatases, the flip side of kinase activity, are a perfect example. |
The Motley Fool February 28, 2011 Brian D. Pacampara |
Next-Generation Drug Technologies Battle It Out Alnylam and Sangamo BioSciences have different ways to manipulate proteins to fight disease. |
Chemistry World September 23, 2008 Simon Hadlington |
Nanoparticles Hide Behind Protein Cloak Polymer nanoparticles suspended in human blood become cloaked in plasma proteins, new research has shown. |
Technology Research News June 18, 2003 |
Protein traps nanoparticles Researchers from the University of Tokyo in Japan have adapted a tubular bacterial protein for technological applications by coaxing it to combine with individual luminescent semiconductor nanoparticles. |
Chemistry World November 13, 2014 Katrina Kramer |
Persuading proteins to form porous polyhedra Researchers in the US have designed a hollow cube out of naturally occurring proteins, something that was previously only possible with DNA. |
Chemistry World January 5, 2007 Victoria Gill |
PEG Makes Cheaper Drugs for Developing Countries UK and Indian scientists have embarked on a collaboration to develop a new protein-based treatment for hepatitis C, which they say will provide an affordable drug urgently needed in countries where resources are limited. |
Chemistry World March 29, 2009 Lewis Brindley |
Gene gels pump out proteins Gels made with genes incorporated into the structure could soon make protein production cheaper and easier, according to researchers in the US. |
Chemistry World November 27, 2013 Jennifer Newton |
A cytochrome from scratch Artificial proteins could be closer to participating in natural biochemical pathways after researchers show that bacteria will process amino acid sequences entirely unrelated to any natural protein to produce a fully functioning cytochrome. |
Chemistry World September 18, 2012 Harriet Brewerton |
Colorful metal detection Scientists in China have developed a sensor that can indicate the presence of heavy metal ions in a sample with a simple color change by using aptamers. Aptamers are single-stranded DNA or RNA molecules. |
HHMI Bulletin February 2011 Michele Solis |
Right Before Your Eyes Coupling protein sequence to function, thousands of variants at a time. |
Reactive Reports Issue 51 David Bradley |
Protein Crystals Trapped Researchers have developed a new technique for crystallizing proteins, which could open up a whole range of materials to this powerful analytical technique. |
Chemistry World August 17, 2011 Jon Cartwright |
Plasma Treatment to Use Patient's Proteins to Improve Medical Device Biocompatibility Researchers have developed a plasma treatment that can make any medical device biocompatible by sticking a patient's own proteins to it. |
Chemistry World August 24, 2009 Phillip Broadwith |
'Chemical nose' sensor sniffs blood protein profile US scientists have developed a sensor system for profiling the protein content of human blood serum without needing individual receptors for each separate protein. |
Reactive Reports September 2007 David Bradley |
Light Controlled Magic Bullet Researchers have developed a new light-controlled drug-delivery system they claim could minimize side effects. |
Bio-IT World May 19, 2004 |
Special Delivery TAT tagging has aroused keen interest in biotech. |
Chemistry World December 21, 2006 Henry Nicholls |
Silent SNPs Serve up a Structural Surprise The sequence of amino acids no longer dictates the structure and function of a protein according to a surprising new paper. |
Chemistry World September 25, 2009 Simon Hadlington |
New MRI protein probe Researchers in Japan have invented a new way to detect the presence of proteins in cells and tissues by magnetic resonance imaging. |
Chemistry World October 24, 2008 Hayley Birch |
Proteins swap partners UK researchers have discovered that proteins which use metal cofactors can be surprisingly promiscuous metal binders, happily taking up the 'wrong' metal. |
Chemistry World August 3, 2007 Simon Hadlington |
Making Light Work of Drug Release UK researchers have borrowed a technique from organic synthetic chemistry to develop a new type of drug-release system that is activated by light. |
Bio-IT World September 11, 2003 Mark D. Uehling |
Fishing Chips The next generation of protein microarrays from the likes of Protometrix and Molecular Staging may threaten the early leads of Biacore and Ciphergen -- and work so well that drug companies won't want them. |
Chemistry World August 26, 2008 Fred Campbell |
High-throughput protein microarrays on the way A new method to rapidly generate protein microarrays has been developed by UK researchers at the University of Manchester. |
The Motley Fool June 29, 2011 Brian Orelli |
Doubling Up in Biotech Lilly hits multiple targets with one drug. |
Chemistry World June 14, 2011 |
A New Spin on Protein NMR A new technique will allow researchers to study protein structure in greater detail using NMR. |
Chemistry World November 2006 Philip Ball |
Opinion: The Crucible Here are some of the latest instalments in the ongoing story of how protein misfolding causes neurodegenerative diseases -- a story that is not solely about developing clinical treatments or preventative medicines, but which goes to the heart of proteins' role as the stuff of life. |
The Motley Fool December 31, 2009 Brian Orelli |
Make Money Even When Drugs Fail Biotech growth potential without as much risk can come from innovations that help drugmakers discover new drugs. |
Chemistry World October 27, 2014 Tim Wogan |
Folding rules used to build unnatural proteins Scientists in the UK and US have designed and synthesized unnatural protein structures, using theoretical calculations to explore the factors affecting protein folding and stability. |
Bio-IT World June 12, 2002 Mark D. Uehling |
Putting Proteins in Their Place Will a 'periodic table' of proteins help classify the ungainly beasts? |
Bio-IT World June 12, 2002 Karen Hopkin |
Computational Biologists Join the Fold CASP5 competitors compare the best algorithms for modeling the 3-D structure of proteins -- an exercise that could lead to new insights into the pathogenesis and treatment of disease. |
Chemistry World April 15, 2015 Christopher Barnard |
Hydrogel with a basic instinct for drug delivery A self-assembling hydrogel with nanofibers that specifically capture and release anti-inflammatory compounds has been created for applications in targeted drug delivery. |
Chemistry World December 2007 Derek Lowe |
Column: In the Pipeline The challenge of biologics. |
BusinessWeek May 24, 2004 Arlene Weintraub |
Regenerative Medicine's Slow Start Scientists think proteins that spur the body to heal could make powerful drugs, but harnessing that potential has been tough |
Chemistry World July 20, 2009 Philip Ball |
Researchers form first liquid protein Chemists at the University of Bristol, UK and their colleagues, in collaboration with the Max Planck Institute for Colloid and Interface Research in Golm, Germany, have figured out how to convert pure proteins into a liquid state, without any solvent. |
Chemistry World July 6, 2007 Michael Gross |
Predicting How Proteins Fold Researchers in Italy and the UK have now developed a computational approach that can simulate the folding of membrane proteins in atomic detail. |
Chemistry World June 6, 2010 Philip Ball |
Blood-like liquid protein formed A liquid form of the oxygen-binding protein myoglobin retains its biological function even though it seems virtually water-free, researchers have found. |
Chemistry World October 20, 2014 Katie Bayliss |
Making light of food allergies Researchers in Spain are taking steps towards 'allergy-free' food, by treating allergy-inducing proteins with a pulsed light treatment that makes them easier to digest. |
Chemistry World February 13, 2014 Philip Ball |
Ice core to antifreeze protein's inner workings The antifreeze protein that protects the winter flounder from sub-zero temperatures has been found to have an odd structure. |
Prepared Foods February 2008 Sharon Book |
Article: Protein Ingredients for Health and Texture A variety of soy, dairy and egg proteins are available for the food formulator to obtain the desired texture in a food or beverage. |