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Chemistry World October 2, 2012 Fiona McKenzie |
Protein sorting within cells US scientists have used magnetic nanoparticles with specific ligands to latch on to and visualize specific proteins in living cells. |
Chemistry World September 23, 2008 Simon Hadlington |
Nanoparticles Hide Behind Protein Cloak Polymer nanoparticles suspended in human blood become cloaked in plasma proteins, new research has shown. |
Bio-IT World September 11, 2003 Mark D. Uehling |
Fishing Chips The next generation of protein microarrays from the likes of Protometrix and Molecular Staging may threaten the early leads of Biacore and Ciphergen -- and work so well that drug companies won't want them. |
Technology Research News June 18, 2003 |
Protein traps nanoparticles Researchers from the University of Tokyo in Japan have adapted a tubular bacterial protein for technological applications by coaxing it to combine with individual luminescent semiconductor nanoparticles. |
Chemistry World May 26, 2011 Russell Johnson |
Hunting elusive green fluorescent proteins After a 40 year hunt, scientists have tracked down the genes responsible for fluorescent proteins in Obelia medusa - a type of jellyfish. Knowledge of these genes could lead to new fluorescent protein tags for use in cell biology. |
Chemistry World June 14, 2011 |
A New Spin on Protein NMR A new technique will allow researchers to study protein structure in greater detail using NMR. |
Chemistry World March 17, 2009 Phillip Broadwith |
Electronic 'nose' could shed light on sense of smell Korean researchers have combined human smell receptors with nanotechnology to create a new kind of 'bio-electronic nose' |
Technology Research News September 24, 2003 Kimberly Patch |
Heated plastic holds proteins One important task for biochips is sorting proteins, but it's tricky business getting protein molecules to be where you want them and stay away from where you don't. A tiny, plastic-coated hot plate allows scientists to trap and release proteins on command. |
Chemistry World October 9, 2011 Simon Hadlington |
New probe throws light on cellular lipids Scientists in the US have developed a new sensor that can track and measure lipids in living cells. |
Chemistry World February 28, 2011 Hayley Birch |
Protein nanotubes trap viruses Japanese researchers have used nanotubes made from human blood proteins to trap hepatitis B virus. They say their work lays the foundations for a new chemistry of protein-based nanotubes with biomedical applications. |
Chemistry World August 20, 2008 |
Spying on Self-Assembly Proteins attaching to gold nanoparticles don't mill around randomly, but organise into clusters, according to UK scientists who say they have for the first time spied in detail peptides assembling on a surface. |
Chemistry World May 5, 2009 Phillip Broadwith |
Don't FRET over broken polymers Fluorescent proteins could one day help identify microscopic cracks and damage in polymer materials, allowing them to be monitored to prevent failure in load-bearing applications such as in aerospace and biomedical devices. |
Chemistry World September 25, 2009 Simon Hadlington |
New MRI protein probe Researchers in Japan have invented a new way to detect the presence of proteins in cells and tissues by magnetic resonance imaging. |
Bio-IT World July 2005 Robert M. Frederickson |
Amassing Mass Spectrometry Tools Mass spectrometry is a key tool in the effort to identify protein biomarkers of human disease. Manufacturers have met major challenges in adapting this technology to protein discovery, both qualitatively and quantitatively. |
Bio-IT World February 11, 2005 Kevin Davies |
In Living Color Researchers have developed a palette of fluorescent proteins to complement the green fluorescent protein (GFP), a stable of cell biology for a decade. |
Technology Research News October 20, 2004 Eric Smalley |
Biochip spots single viruses A detector recently built from nanowire transistors can identify individual virus particles in real time in unpurified samples. Labs-on-a-chip based on the device could be used to monitor diseases. |
Chemistry World April 2, 2009 Ned Stafford |
Fluorescent probes take screening to next level Researchers have developed a new high-throughput screening technique that could shed light on the biochemical activities of numerous proteins about which little is currently known. |
Chemistry World January 10, 2012 Phillip Broadwith |
Amino acid residues give away bloodstain's age Chemists in the US have developed a quick and simple way to find out how old bloodstains are using natural fluorescence measurements. |
Chemistry World August 26, 2008 Fred Campbell |
High-throughput protein microarrays on the way A new method to rapidly generate protein microarrays has been developed by UK researchers at the University of Manchester. |
Chemistry World January 19, 2011 Jon Cartwright |
Modified protein binders give shortcut to drugs The method, which involves attaching polypeptides to the binders, could help reduce the work required to develop protein binders into safer drugs. |
Bio-IT World April 16, 2004 |
Portraits in Proteomics Advances in identifying protein biomarkers are spurring new hope in cancer diagnostics, expediting detection and easing testing. |
Chemistry World July 2006 John Bonner |
Insect Detectives Chemists and biologists are harnessing the powerful sense of smell that insects possess to devise applications from detecting rotten tomatoes to controlling one of the deadliest diseases in Africa. |
Chemistry World May 9, 2007 James Mitchell Crow |
Controlling prion folding US scientists report that prions, infamously linked to mad cow disease, have crucial subsections that control their behavior, including whether or not they can cross between species. |
Chemistry World April 27, 2006 |
`Sticky Trees' Glue Molecules to Proteins Researchers have developed a chemical glue that binds molecules to proteins without compromising protein function. The method could be used to modify a wide range of proteins for a variety of purposes, such as in the development of new protein-based therapies. |
Reactive Reports Issue 51 David Bradley |
Protein Crystals Trapped Researchers have developed a new technique for crystallizing proteins, which could open up a whole range of materials to this powerful analytical technique. |
Chemistry World October 8, 2008 Lewis Brindley |
Green fluorescent protein takes Nobel Prize The protein, first isolated from a jellyfish, is now routinely used as a brightly glowing marker to track the positions and interactions of proteins in cells. |
American Family Physician January 1, 2005 Theodore X. O'Connell et al. |
Understanding and Interpreting Serum Protein Electrophoresis This lab examination is used to identify patients with multiple myeloma and other serum protein disorders. Electrophoresis separates proteins based on their physical proper-ties, and the subsets of these proteins are used in interpreting the results. |
Chemistry World April 26, 2009 Simon Hadlington |
Glowing protein in 'animal photosynthesis' Scientists have discovered that a glowing protein found in some exotic marine animals and used widely as a 'marker' in molecular biology has another remarkable property |
Chemistry World September 12, 2014 Hayley Simon |
Coated nanoparticles show Alzheimer's promise Nanoparticles coated in an amino acid polymer have been found to prevent the formation of amyloid fibrils -- incorrectly folded protein fibers associated with the development of neurodegenerative diseases. |
Chemistry World June 19, 2012 Anthony King |
Nanoparticles linked to rheumatoid arthritis Three types of nanoparticles were found to ramp up protein citrullination in cell cultures, a change that can make the body think native proteins are foreign. This process has previously been linked to autoimmune disease. |
Reactive Reports September 2005 David Bradley |
When Good Turns Bad Prions, the protein-like pathogens at the heart of the fatal brain disorder CJD, so-called mad cow disease, and related diseases can rapidly "remodel" good proteins into bad, according to US scientists, who have demonstrated this for the first time in living cells. |
Bio-IT World June 12, 2002 Mark D. Uehling |
Putting Proteins in Their Place Will a 'periodic table' of proteins help classify the ungainly beasts? |
Bio-IT World April 15, 2003 Robert M. Frederickson |
Protein Chemistry Surfaces Protein chips seek to do for protein expression profiling what DNA chips did for RNA expression. |
Chemistry World December 12, 2011 Simon Hadlington |
Zwitterion approach to stabilizing drug proteins Researchers in the US have discovered a new way to stabilize and protect protein molecules without affecting the protein's biological activity. |
Chemistry World May 1, 2012 David Bradley |
A colorful way to size up nanoparticles Researchers in China have now developed a straightforward light-scattering technique to estimate the size of gold nanoparticles in the 35 to 110nm range. |
Chemistry World May 5, 2011 Simon Hadlington |
Revolutionary new single-cell labelling method Researchers in the US and Canada have combined mass spectrometry with a technique called flow cytometry to follow dozens of biochemical markers on individual cells simultaneously. |
Chemistry World May 2, 2007 Michael Gross |
Protein Printboard Chemists in the Netherlands have created nanoscale structures that can immobilize proteins with exquisite control over specificity, strength and orientation. |
HHMI Bulletin Feb 2011 |
DNA Curtains How proteins behave in such a crash test gives scientists data about their structural integrity, how they attach to DNA, and how they behave in a cell. |
Industrial Physicist Aug/Sep 2003 Ineke Malsch |
Protein research calls for advanced instruments The science of protein interactions is becoming a major tool in biomedical and drug development research. Carrying out and advancing such studies more efficiently and effectively, however, will require new, cutting-edge instrumentation. |
Chemistry World October 24, 2008 Hayley Birch |
Proteins swap partners UK researchers have discovered that proteins which use metal cofactors can be surprisingly promiscuous metal binders, happily taking up the 'wrong' metal. |
Chemistry World July 21, 2011 Elinor Richards |
Cell Control to Change Cell Function US scientists can now control the reactions occurring inside cells. |
Chemistry World July 20, 2009 Philip Ball |
Researchers form first liquid protein Chemists at the University of Bristol, UK and their colleagues, in collaboration with the Max Planck Institute for Colloid and Interface Research in Golm, Germany, have figured out how to convert pure proteins into a liquid state, without any solvent. |
Chemistry World November 2008 |
A glowing green Nobel The molecule that revolutionized and illuminated cell biology started with a jellyfish. Lewis Brindley tells the story of this year's Nobel prize for chemistry |
Chemistry World October 8, 2008 Sarah Houlton |
Artificial protein chemistry licensed to industry UK researchers are licensing to industry their method of making artificial proteins by chemically modifying individual amino acid structures. |
Chemistry World August 19, 2009 Hayley Birch |
Gold nanoparticles detect cancer Chinese scientists have used gold nanoparticles as ultrasensitive fluorescent probes to detect cancer biomarkers in human blood. |
Chemistry World January 9, 2013 Laura Howes |
Antifreeze protein's watery dance Most animals left in -30 C temperatures wouldn't last very long. Not only would they get hypothermia, but the water in their bodies would start to freeze. Some animals and plants, however, use antifreeze proteins to keep ice at bay. |
Chemistry World July 31, 2012 David Bradley |
Hydrogels can release drugs one at a time A hydrogel that can be programmed to release different protein drugs one after the other rather than all at once could simplify the delivery of complex therapeutic regimens for various diseases. |
Bio-IT World August 13, 2002 Malorye Branca |
The Proteomics Odyssey Efforts to map the constellation of protein interactions in humans gather momentum as companies vie to provide tools to capitalize on the potential of proteomics. But can proteomics prevail where some feel genomics has failed? |
Chemistry World December 20, 2011 Simon Hadlington |
pH adjustable protein micro-lenses Scientists in China have used a common protein to create tiny optical lenses, a few tens of micrometres in diameter, whose focus can be adjusted simply by changing the pH of the surrounding medium. |
Chemistry World October 8, 2014 |
Super-resolution light microscopy wins chemistry Nobel The 2014 chemistry Nobel prize has been given to three pioneers of biomedical imaging, whose work has enabled nanoscale features within cells to be captured in exquisite detail. |