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HHMI Bulletin
Aug 2010
Richard Saltus
Three-Dimensional Cell Cultures Thinking big but starting small, Sangeeta Bhatia is closing in on her ambitious goal: growing human livers in the lab from scratch. mark for My Articles similar articles
Chemistry World
January 23, 2011
James Urquhart
Novel nanoparticle filter Israeli researchers have created a recyclable membrane based on supramolecular linkages that can be used to filter nanoparticles. mark for My Articles similar articles
Chemistry World
February 21, 2014
Phillip Broadwith
Refined gels for cultured cells UK start-up Biogelx is developing self-assembled peptide hydrogels that can provide support to growing cells, but also present well-defined surface chemistry to help cell biologists address biological problems. mark for My Articles similar articles
Chemistry World
May 10, 2013
Michael Parkin
Super Glue for cells Scientists in Canada have made a super-strong cell membrane adhesive and used it to stick red blood cells together. The polymer, based on the phospholipid head group phosphatidyl choline, could be used to secure cells in particular positions for tissue engineering and wound closure. mark for My Articles similar articles
Chemistry World
April 19, 2011
Simon Hadlington
Cell factories package drugs for delivery Scientists in Australia and Germany have used living cells as 'factories' to encapsulate particles such as drugs in biological membranes. mark for My Articles similar articles
Chemistry World
July 21, 2011
Elinor Richards
Cell Control to Change Cell Function US scientists can now control the reactions occurring inside cells. mark for My Articles similar articles
Chemistry World
May 22, 2009
Phillip Broadwith
'Printing' organs with hydrogels Dutch researchers have developed a way to 'print' stable cell-containing scaffolds, creating a method that could one day be used to help make tailor-made tissue grafts mark for My Articles similar articles
Chemistry World
June 9, 2008
Simon Hadlington
Artificial virus silences genes Scientists in Korea have created an artificial virus that can target the nucleus of cancer cells and knock out specific genes. mark for My Articles similar articles
Chemistry World
January 26, 2011
Anna Watson
Channelling deeper to target breast cancer US scientists have developed a model of the breast ductal system that could be used to discover abnormal cells or deliver drugs at locations further along the ducts than other techniques. The model fits on a slide, enabling on-chip experiments. mark for My Articles similar articles
Chemistry World
July 1, 2012
Mellisae Fellet
3D printed sugar network to feed engineered organs US researchers can build vessels into a cell-containing gel -- the beginnings of a thick tissue. Scientists form the gel around a lattice of printed sugar fibers. The fibers dissolve after the gel sets, leaving a network of channels that carry nutrients like blood vessels. mark for My Articles similar articles
Chemistry World
September 20, 2012
Ian Le Guillou
Self-assembling, squeezy nanotubes made Researchers have developed dynamic nanotubes that open and shut depending on temperature. mark for My Articles similar articles
Chemistry World
May 30, 2007
Victoria Gill
Salty Water Makes Barnacles Stick Researchers recently found that the saltiness of seawater triggers barnacles' cement-like natural bond. mark for My Articles similar articles
HHMI Bulletin
February 2011
Sarah C.P. Williams
Enforcing Order Changing the spatial arrangement of molecules in a cell can alter their functions. mark for My Articles similar articles
Chemistry World
March 27, 2008
Lewis Brindley
Membrane Sacs Made in Minutes Strong, flexible, centimetre-sized membrane sacs that could be used to hold cells for study have been developed by chemists in the US. mark for My Articles similar articles
Chemistry World
July 24, 2012
Rachel Cooper
Light speeds up new cell growth Scientists from Singapore have combined a photovoltaic polymer with a biocompatible polymer to make a nanofiber-based scaffold that can grow cells for skin regeneration. mark for My Articles similar articles
Chemistry World
July 13, 2009
Lewis Brindley
Getting a look at water wires Indian chemists have trapped tiny strands of water inside peptide nanotubes - allowing the researchers to take a direct look at how small amounts of water behave in a confined environment. mark for My Articles similar articles
Chemistry World
November 15, 2012
David Bradley
DNA folds up into a synthetic ion channel An artificial ion channel that spans a synthetic lipid membrane has been created using DNA origami by researchers in Germany and the US. mark for My Articles similar articles
Chemistry World
August 12, 2011
Manisha Lalloo
Unraveling cell membranes to understand drugs Researchers in Sweden have found a way to create flattened cell membranes, known as supported lipid bilayers, out of real cell structures. mark for My Articles similar articles
Technology Research News
June 29, 2005
Eric Smalley
Cell combo yields blood vessels Researchers experiment with methods of getting blood vessels to grow in replacement organs before the tissue is placed in the body. mark for My Articles similar articles
Chemistry World
June 27, 2010
Simon Hadlington
Nanoparticles allow remote control of cells In an experiment reminiscent of the mind-control rays that featured prominently in B-movies from the 1950s, scientists in the US have used a magnetic field to alter the behavior of an animal. mark for My Articles similar articles
Chemistry World
June 18, 2015
David Bradley
Ultra-thin membranes for solute separation Polymer membranes that are extremely thin, yet strong and stable, could cut the costs of separating organic molecules and reduce energy requirements in the chemical industry. mark for My Articles similar articles
Bio-IT World
May 19, 2004
Special Delivery TAT tagging has aroused keen interest in biotech. mark for My Articles similar articles
Chemistry World
November 21, 2012
James Urquhart
Two-faced particles self-assemble in sync US scientists have synchronized the motion of colloidal magnetic spheres with a rotating magnetic field and found that the particles self-organize into micrometer-sized tubes. mark for My Articles similar articles
Chemistry World
September 1, 2008
James Mitchell Crow
Drug discovery on a chip Scientists in the US have, for the first time, used microfluidics to discover drug leads. The team's lab-on-a-chip device revealed inhibitors of a key membrane-bound protein in hepatitis C virus mark for My Articles similar articles
Chemistry World
April 29, 2013
Caryl Richards
Protein origami sets scene for designer structures A world first in the art of protein origami has been attained with a novel method of folding a polypeptide chain into a three-dimensional tetrahedron. mark for My Articles similar articles
Chemistry World
March 1, 2009
Nina Notman
Inorganic crystals turned into tubes Inorganic crystals dropped into water can be grown into long 'microtubes' of controlled size and shape, chemists in the UK have discovered. mark for My Articles similar articles
Technology Research News
January 29, 2003
Kimberly Patch
Tiny hole guides atoms against tide Researchers in Poland have made a synthetic device that uses an electrical field and an extremely small, conical pore in a thin film of material to coax potassium ions through the artificial membrane against their electrochemical potential. mark for My Articles similar articles
Chemistry World
November 25, 2013
Carla Pegoraro
Steering cells towards biocomputers Bacterial toxins that undergo unique cell interactions have been used to perform logic functions by researchers in Germany. This innovation will help push the limits of synthetic biology. mark for My Articles similar articles
IEEE Spectrum
August 2006
Schoenbach et al.
Zap Extreme voltage could be a surprisingly delicate tool in the fight against cancer. The list of effects that scientists have achieved using nanoseconds-long pulses is growing rapidly, though their actual use as a medical treatment is still years away. mark for My Articles similar articles
Technology Research News
March 23, 2005
Eric Smalley
Inkjet prints human cells Scientists tackle challenge of putting the right cells in the right places and ensuring that the cells survive the rough ride. mark for My Articles similar articles
Chemistry World
May 29, 2014
Carla Pegoraro
Dual warhead kills and disarms bacteria A compound that kills bacteria and cleaves their DNA to prevent them passing on drug-resistant genes has been designed by researchers in India. mark for My Articles similar articles
Chemistry World
September 19, 2007
Lewis Brindley
Cell Destruction by Gel Implosion Scientists in Hong Kong have shown that creating a gel inside bacterial cells can stunt their growth. This research is a step towards developing novel treatments that would target rapidly-reproducing cells such antibiotic-resistant superbugs. mark for My Articles similar articles
Chemistry World
February 28, 2013
Andy Extance
Chemical transport defines 'Goldilocks' cell size A US team has suggested molecular movement as an answer to the question of why cells are the size they are. A question that they say 'still awaits an answer from first principles'. mark for My Articles similar articles
HHMI Bulletin
Spring 2013
Nicole Kresge
A Structural Toolbox Natalie Strynadka wants to design a better antibiotic. Her strategy: learn about the molecules bacteria use to invade cells. Her tool: structural biology. mark for My Articles similar articles
Chemistry World
July 6, 2007
Michael Gross
Predicting How Proteins Fold Researchers in Italy and the UK have now developed a computational approach that can simulate the folding of membrane proteins in atomic detail. mark for My Articles similar articles
Chemistry World
October 25, 2007
Elusive Drug Target Finally Seen Scientists have captured an atomic-scale picture of a receptor protein from a family that is the target of thousands of drugs. mark for My Articles similar articles
Chemistry World
October 9, 2006
Michael Gross
Miniature Microbicides Researchers have created miniature antimicrobial peptides that contain only four (as opposed to the usual 12-50) amino acid residues combined with a fatty acid. mark for My Articles similar articles
Chemistry World
June 16, 2014
James Urquhart
Handshake assembles new emulsions All it takes to make new stable emulsions with tuneable and novel properties is to give a simple mixture of water, solvent and peptide derivatives a quick shake by hand. mark for My Articles similar articles
Chemistry World
October 31, 2010
Michael Gross
Kiss of death for cancer cells Scientists have deciphered the surprising structure of the perforin pore, which delivers the 'kiss of death' to virus-infected cells and cancer cells in the body. mark for My Articles similar articles
Chemistry World
April 4, 2012
Harriet Brewerton
Speeding up wound healing Scientists in China have developed a material that reduces the time required for a skin wound to heal. mark for My Articles similar articles
Technology Research News
November 3, 2004
Kimberly Patch
DNA in nanotubes sorts molecules Researchers have made a synthetic membrane that recognizes certain biochemical molecules and allows them to pass through. The method could be used to make biological sensors like those needed for genetics research, and to sort biological molecules, mark for My Articles similar articles
Chemistry World
September 21, 2010
Hayley Birch
Self-pumping membrane mimics cell machinery US researchers have imitated the transport functions of biological membranes by incorporating tiny pumps into synthetic membranes. They say their 'self-pumping' mimics could be used in compartment-less fuel cells. mark for My Articles similar articles
Chemistry World
February 3, 2015
Jennifer Newton
Chip-on-a-cell Colleagues at the Institute of Microelectronics Barcelona affixed polysilicon chips, which act as barcodes, onto the outer surface of the zona pellucida, a membrane that surrounds immature egg.cells and embryos. mark for My Articles similar articles
Chemistry World
November 10, 2006
Victoria Gill
Healing Threads Spun From Living Cells Researchers have successfully made microthreads from polymers containing living cells, using a technique called electrospinning. These biologically active threads could be formed into medical scaffolds, to deliver cells directly to tissue and promote healing. mark for My Articles similar articles
Chemistry World
January 26, 2012
David Bradley
Leaky graphene oxide lets water pour through UK researchers have created a graphene-based membrane that allows water through but not helium. mark for My Articles similar articles
Chemistry World
April 23, 2013
David Bradley
A sweet switch for an ageing heart Studies revealing how the protein elastin -- found in heart tissue and blood vessels -- responds electrically to glucose could offer new clues to problems that arise as we get older, including loss of elasticity in major blood vessels and arteriosclerosis. mark for My Articles similar articles
Chemistry World
August 22, 2008
Hayley Birch
Drug uptake rule challenged A study by UK scientists apparently contradicts a 100-year-old rule thought to govern the rate at which molecules cross biological membranes. mark for My Articles similar articles
Chemistry World
December 12, 2013
Jeanne Therese Andres
Kiss-and-run drug delivery Carriers that release hydrophobic substances at cell membranes but do not enter the cells themselves could be the foundation for a new way to deliver drugs into cells, according to a team of scientists in Germany. mark for My Articles similar articles
Chemistry World
September 14, 2009
Simon Hadlington
New 'on-off' membrane for drug delivery A team led by Daniel Kohane of Harvard Medical School in Boston, US, harnessed the thermosensitive properties of poly(N-isopropylacrylamide) to form the basis of the new system. mark for My Articles similar articles
Chemistry World
February 2, 2014
Emma Stoye
Artificial membrane harvests light like a cell Photosensitive compounds built into an artificial membrane can capture light energy in the same way as proton pumps found in biological cells. mark for My Articles similar articles