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HHMI Bulletin Aug 2010 Richard Saltus |
Three-Dimensional Cell Cultures Thinking big but starting small, Sangeeta Bhatia is closing in on her ambitious goal: growing human livers in the lab from scratch. |
Chemistry World January 23, 2011 James Urquhart |
Novel nanoparticle filter Israeli researchers have created a recyclable membrane based on supramolecular linkages that can be used to filter nanoparticles. |
Chemistry World February 21, 2014 Phillip Broadwith |
Refined gels for cultured cells UK start-up Biogelx is developing self-assembled peptide hydrogels that can provide support to growing cells, but also present well-defined surface chemistry to help cell biologists address biological problems. |
Chemistry World May 10, 2013 Michael Parkin |
Super Glue for cells Scientists in Canada have made a super-strong cell membrane adhesive and used it to stick red blood cells together. The polymer, based on the phospholipid head group phosphatidyl choline, could be used to secure cells in particular positions for tissue engineering and wound closure. |
Chemistry World April 19, 2011 Simon Hadlington |
Cell factories package drugs for delivery Scientists in Australia and Germany have used living cells as 'factories' to encapsulate particles such as drugs in biological membranes. |
Chemistry World July 21, 2011 Elinor Richards |
Cell Control to Change Cell Function US scientists can now control the reactions occurring inside cells. |
Chemistry World May 22, 2009 Phillip Broadwith |
'Printing' organs with hydrogels Dutch researchers have developed a way to 'print' stable cell-containing scaffolds, creating a method that could one day be used to help make tailor-made tissue grafts |
Chemistry World June 9, 2008 Simon Hadlington |
Artificial virus silences genes Scientists in Korea have created an artificial virus that can target the nucleus of cancer cells and knock out specific genes. |
Chemistry World January 26, 2011 Anna Watson |
Channelling deeper to target breast cancer US scientists have developed a model of the breast ductal system that could be used to discover abnormal cells or deliver drugs at locations further along the ducts than other techniques. The model fits on a slide, enabling on-chip experiments. |
Chemistry World July 1, 2012 Mellisae Fellet |
3D printed sugar network to feed engineered organs US researchers can build vessels into a cell-containing gel -- the beginnings of a thick tissue. Scientists form the gel around a lattice of printed sugar fibers. The fibers dissolve after the gel sets, leaving a network of channels that carry nutrients like blood vessels. |
Chemistry World September 20, 2012 Ian Le Guillou |
Self-assembling, squeezy nanotubes made Researchers have developed dynamic nanotubes that open and shut depending on temperature. |
Chemistry World May 30, 2007 Victoria Gill |
Salty Water Makes Barnacles Stick Researchers recently found that the saltiness of seawater triggers barnacles' cement-like natural bond. |
HHMI Bulletin February 2011 Sarah C.P. Williams |
Enforcing Order Changing the spatial arrangement of molecules in a cell can alter their functions. |
Chemistry World March 27, 2008 Lewis Brindley |
Membrane Sacs Made in Minutes Strong, flexible, centimetre-sized membrane sacs that could be used to hold cells for study have been developed by chemists in the US. |
Chemistry World July 24, 2012 Rachel Cooper |
Light speeds up new cell growth Scientists from Singapore have combined a photovoltaic polymer with a biocompatible polymer to make a nanofiber-based scaffold that can grow cells for skin regeneration. |
Chemistry World July 13, 2009 Lewis Brindley |
Getting a look at water wires Indian chemists have trapped tiny strands of water inside peptide nanotubes - allowing the researchers to take a direct look at how small amounts of water behave in a confined environment. |
Chemistry World November 15, 2012 David Bradley |
DNA folds up into a synthetic ion channel An artificial ion channel that spans a synthetic lipid membrane has been created using DNA origami by researchers in Germany and the US. |
Chemistry World August 12, 2011 Manisha Lalloo |
Unraveling cell membranes to understand drugs Researchers in Sweden have found a way to create flattened cell membranes, known as supported lipid bilayers, out of real cell structures. |
Technology Research News June 29, 2005 Eric Smalley |
Cell combo yields blood vessels Researchers experiment with methods of getting blood vessels to grow in replacement organs before the tissue is placed in the body. |
Chemistry World June 27, 2010 Simon Hadlington |
Nanoparticles allow remote control of cells In an experiment reminiscent of the mind-control rays that featured prominently in B-movies from the 1950s, scientists in the US have used a magnetic field to alter the behavior of an animal. |
Chemistry World June 18, 2015 David Bradley |
Ultra-thin membranes for solute separation Polymer membranes that are extremely thin, yet strong and stable, could cut the costs of separating organic molecules and reduce energy requirements in the chemical industry. |
Bio-IT World May 19, 2004 |
Special Delivery TAT tagging has aroused keen interest in biotech. |
Chemistry World November 21, 2012 James Urquhart |
Two-faced particles self-assemble in sync US scientists have synchronized the motion of colloidal magnetic spheres with a rotating magnetic field and found that the particles self-organize into micrometer-sized tubes. |
Chemistry World September 1, 2008 James Mitchell Crow |
Drug discovery on a chip Scientists in the US have, for the first time, used microfluidics to discover drug leads. The team's lab-on-a-chip device revealed inhibitors of a key membrane-bound protein in hepatitis C virus |
Chemistry World April 29, 2013 Caryl Richards |
Protein origami sets scene for designer structures A world first in the art of protein origami has been attained with a novel method of folding a polypeptide chain into a three-dimensional tetrahedron. |
Chemistry World March 1, 2009 Nina Notman |
Inorganic crystals turned into tubes Inorganic crystals dropped into water can be grown into long 'microtubes' of controlled size and shape, chemists in the UK have discovered. |
Technology Research News January 29, 2003 Kimberly Patch |
Tiny hole guides atoms against tide Researchers in Poland have made a synthetic device that uses an electrical field and an extremely small, conical pore in a thin film of material to coax potassium ions through the artificial membrane against their electrochemical potential. |
Chemistry World November 25, 2013 Carla Pegoraro |
Steering cells towards biocomputers Bacterial toxins that undergo unique cell interactions have been used to perform logic functions by researchers in Germany. This innovation will help push the limits of synthetic biology. |
IEEE Spectrum August 2006 Schoenbach et al. |
Zap Extreme voltage could be a surprisingly delicate tool in the fight against cancer. The list of effects that scientists have achieved using nanoseconds-long pulses is growing rapidly, though their actual use as a medical treatment is still years away. |
Technology Research News March 23, 2005 Eric Smalley |
Inkjet prints human cells Scientists tackle challenge of putting the right cells in the right places and ensuring that the cells survive the rough ride. |
Chemistry World May 29, 2014 Carla Pegoraro |
Dual warhead kills and disarms bacteria A compound that kills bacteria and cleaves their DNA to prevent them passing on drug-resistant genes has been designed by researchers in India. |
Chemistry World September 19, 2007 Lewis Brindley |
Cell Destruction by Gel Implosion Scientists in Hong Kong have shown that creating a gel inside bacterial cells can stunt their growth. This research is a step towards developing novel treatments that would target rapidly-reproducing cells such antibiotic-resistant superbugs. |
Chemistry World February 28, 2013 Andy Extance |
Chemical transport defines 'Goldilocks' cell size A US team has suggested molecular movement as an answer to the question of why cells are the size they are. A question that they say 'still awaits an answer from first principles'. |
HHMI Bulletin Spring 2013 Nicole Kresge |
A Structural Toolbox Natalie Strynadka wants to design a better antibiotic. Her strategy: learn about the molecules bacteria use to invade cells. Her tool: structural biology. |
Chemistry World July 6, 2007 Michael Gross |
Predicting How Proteins Fold Researchers in Italy and the UK have now developed a computational approach that can simulate the folding of membrane proteins in atomic detail. |
Chemistry World October 25, 2007 |
Elusive Drug Target Finally Seen Scientists have captured an atomic-scale picture of a receptor protein from a family that is the target of thousands of drugs. |
Chemistry World October 9, 2006 Michael Gross |
Miniature Microbicides Researchers have created miniature antimicrobial peptides that contain only four (as opposed to the usual 12-50) amino acid residues combined with a fatty acid. |
Chemistry World June 16, 2014 James Urquhart |
Handshake assembles new emulsions All it takes to make new stable emulsions with tuneable and novel properties is to give a simple mixture of water, solvent and peptide derivatives a quick shake by hand. |
Chemistry World October 31, 2010 Michael Gross |
Kiss of death for cancer cells Scientists have deciphered the surprising structure of the perforin pore, which delivers the 'kiss of death' to virus-infected cells and cancer cells in the body. |
Chemistry World April 4, 2012 Harriet Brewerton |
Speeding up wound healing Scientists in China have developed a material that reduces the time required for a skin wound to heal. |
Technology Research News November 3, 2004 Kimberly Patch |
DNA in nanotubes sorts molecules Researchers have made a synthetic membrane that recognizes certain biochemical molecules and allows them to pass through. The method could be used to make biological sensors like those needed for genetics research, and to sort biological molecules, |
Chemistry World September 21, 2010 Hayley Birch |
Self-pumping membrane mimics cell machinery US researchers have imitated the transport functions of biological membranes by incorporating tiny pumps into synthetic membranes. They say their 'self-pumping' mimics could be used in compartment-less fuel cells. |
Chemistry World February 3, 2015 Jennifer Newton |
Chip-on-a-cell Colleagues at the Institute of Microelectronics Barcelona affixed polysilicon chips, which act as barcodes, onto the outer surface of the zona pellucida, a membrane that surrounds immature egg.cells and embryos. |
Chemistry World November 10, 2006 Victoria Gill |
Healing Threads Spun From Living Cells Researchers have successfully made microthreads from polymers containing living cells, using a technique called electrospinning. These biologically active threads could be formed into medical scaffolds, to deliver cells directly to tissue and promote healing. |
Chemistry World January 26, 2012 David Bradley |
Leaky graphene oxide lets water pour through UK researchers have created a graphene-based membrane that allows water through but not helium. |
Chemistry World April 23, 2013 David Bradley |
A sweet switch for an ageing heart Studies revealing how the protein elastin -- found in heart tissue and blood vessels -- responds electrically to glucose could offer new clues to problems that arise as we get older, including loss of elasticity in major blood vessels and arteriosclerosis. |
Chemistry World August 22, 2008 Hayley Birch |
Drug uptake rule challenged A study by UK scientists apparently contradicts a 100-year-old rule thought to govern the rate at which molecules cross biological membranes. |
Chemistry World December 12, 2013 Jeanne Therese Andres |
Kiss-and-run drug delivery Carriers that release hydrophobic substances at cell membranes but do not enter the cells themselves could be the foundation for a new way to deliver drugs into cells, according to a team of scientists in Germany. |
Chemistry World September 14, 2009 Simon Hadlington |
New 'on-off' membrane for drug delivery A team led by Daniel Kohane of Harvard Medical School in Boston, US, harnessed the thermosensitive properties of poly(N-isopropylacrylamide) to form the basis of the new system. |
Chemistry World February 2, 2014 Emma Stoye |
Artificial membrane harvests light like a cell Photosensitive compounds built into an artificial membrane can capture light energy in the same way as proton pumps found in biological cells. |