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Chemistry World December 12, 2013 Jeanne Therese Andres |
Kiss-and-run drug delivery Carriers that release hydrophobic substances at cell membranes but do not enter the cells themselves could be the foundation for a new way to deliver drugs into cells, according to a team of scientists in Germany. |
Chemistry World June 27, 2010 Simon Hadlington |
Nanoparticles allow remote control of cells In an experiment reminiscent of the mind-control rays that featured prominently in B-movies from the 1950s, scientists in the US have used a magnetic field to alter the behavior of an animal. |
Chemistry World July 28, 2009 Michael Gross |
DNA to direct and switch off chemo Researchers in the US have developed a new approach to cancer chemotherapy using short DNA strands to help target delivery of the drug directly to cancer cells, and 'call it off' should problems arise. |
Chemistry World September 26, 2006 Fiona Case |
Synchronised Delivery for DNA and Drugs Polymer capsules that can simultaneously deliver drug molecules and DNA into a cell could boost the power of cancer treatments. |
Chemistry World August 22, 2008 Hayley Birch |
Drug uptake rule challenged A study by UK scientists apparently contradicts a 100-year-old rule thought to govern the rate at which molecules cross biological membranes. |
Chemistry World September 14, 2009 Simon Hadlington |
New 'on-off' membrane for drug delivery A team led by Daniel Kohane of Harvard Medical School in Boston, US, harnessed the thermosensitive properties of poly(N-isopropylacrylamide) to form the basis of the new system. |
Chemistry World September 10, 2008 Simon Hadlington |
Failed anxiety drug could treat cancer Scientists believe they have solved the mystery of how a drug originally developed for treating anxiety can kill cancer cells. |
Chemistry World August 12, 2011 Manisha Lalloo |
Unraveling cell membranes to understand drugs Researchers in Sweden have found a way to create flattened cell membranes, known as supported lipid bilayers, out of real cell structures. |
Scientific American July 3, 2006 Jeneen Interlandi |
An Immune Portal Protein may be a key to autoimmune disorders |
Chemistry World December 5, 2007 Jonathan Edwards |
Water Cleaning Membrane Shows Hybrid Vigour Scientists in the US have combined naturally-occurring channel proteins with a new polymer to create a membrane that could be used to deliver drugs or purify water. |
Chemistry World March 31, 2006 Bea Perks |
Nanoparticle Drug Delivery Biodegradable polymers being developed the U.S. offer numerous advantages over current drug delivery systems, say researchers working on ways to deliver anti-inflammatory drugs directly into cells. |
Chemistry World January 26, 2011 Anna Watson |
Channelling deeper to target breast cancer US scientists have developed a model of the breast ductal system that could be used to discover abnormal cells or deliver drugs at locations further along the ducts than other techniques. The model fits on a slide, enabling on-chip experiments. |
Chemistry World June 4, 2008 Simon Hadlington |
Man-made protocell hosts DNA synthesis US researchers have taken a step towards creating a synthetic cell in the laboratory that could resemble the first primitive stirrings of life on Earth. |
HHMI Bulletin Aug 2011 Richard Saltus |
T-Cell Booster Kits A bioengineer remodels cell surfaces to prod the immune system. |
HHMI Bulletin May 2010 Sarah C.P. Williams |
Lab-Grown Liver New cell culture system solves problem of growing liver cells. |
Chemistry World March 9, 2011 Simon Hadlington |
Chemical mystery of antifungal compound solved US researchers have applied synthetic organic chemistry to crack a mystery that has baffled scientists for more than 50 years: how the powerful, naturally occurring antifungal compound amphotericin B interacts with sterols in cell membranes. |
Chemistry World September 19, 2007 Lewis Brindley |
Cell Destruction by Gel Implosion Scientists in Hong Kong have shown that creating a gel inside bacterial cells can stunt their growth. This research is a step towards developing novel treatments that would target rapidly-reproducing cells such antibiotic-resistant superbugs. |
Chemistry World March 16, 2009 Hayley Birch |
Nanodumbbells Target Cancer Cells US scientists have designed nanoparticles that function like 'guided missiles' in the targeted destruction of breast cancer cells. |
Chemistry World June 2011 |
Breaking through the barrier Getting drug molecules into the brain means crossing the defensive blood-brain barrier. Anthony King investigates how chemists are infiltrating the brain's fortress |
Popular Mechanics January 28, 2010 Cassie Rodenberg |
Next-Gen Transplant Techniques Can Stop Organ Rejection About 77 organ transplants are performed each day in the U.S., and more than 101,000 people are on a wait list for body parts such as hearts, skin and veins, according to the Mayo Clinic. |
Chemistry World March 27, 2008 Lewis Brindley |
Membrane Sacs Made in Minutes Strong, flexible, centimetre-sized membrane sacs that could be used to hold cells for study have been developed by chemists in the US. |
Chemistry World October 31, 2010 Michael Gross |
Kiss of death for cancer cells Scientists have deciphered the surprising structure of the perforin pore, which delivers the 'kiss of death' to virus-infected cells and cancer cells in the body. |
Chemistry World June 9, 2008 Simon Hadlington |
Artificial virus silences genes Scientists in Korea have created an artificial virus that can target the nucleus of cancer cells and knock out specific genes. |
Chemistry World April 7, 2009 Lewis Brindley |
Cells get in line Magnetic nanoparticles that 'shepherd' cells into neat lines have been designed by American scientists. |
Pharmaceutical Executive October 1, 2006 Jason McKinnie |
Smaller is Better Everybody has heard about using nanotechnology in drug delivery, but not many people - even specialists in drug development - know quite where the new technology fits in. |
Chemistry World July 7, 2011 Hayley Birch |
Could Life Have Emerged Inside Inorganic Shells? The basic components of cells can operate within the bounds of inorganic membranes made from nanoparticles, a new study shows. |
Chemistry World October 7, 2010 Simon Hadlington |
New light shed on 'photothermal' cell death Photothermal therapy - where tiny particles of a metal are introduced into a cell and heated by laser light to kill the cell - might not work in the way people think, researchers in the UK have discovered. |
Chemistry World July 2, 2007 Michael Gross |
Transistor tuned to ion channel As living cells can detect many compounds with high sensitivity via receptors on their membranes, researchers are keen to exploit them in electronic biosensors. Researchers in Germany now report the feasibility of just such a receptor-cell-transistor biosensor. |
Chemistry World October 25, 2007 |
Elusive Drug Target Finally Seen Scientists have captured an atomic-scale picture of a receptor protein from a family that is the target of thousands of drugs. |
Chemistry World May 10, 2013 Michael Parkin |
Super Glue for cells Scientists in Canada have made a super-strong cell membrane adhesive and used it to stick red blood cells together. The polymer, based on the phospholipid head group phosphatidyl choline, could be used to secure cells in particular positions for tissue engineering and wound closure. |
Reactive Reports Issue 55 David Bradley |
Testing the Byproducts of Cell Death A new approach to testing whether a particular chemotherapy agent is working well in treating a patient's cancer is being developed by UK scientists |
Chemistry World February 11, 2011 David Barden |
Waking up to new possibilities in imaging UK researchers have used a cage-like molecule to smuggle metal ions into cells, which could improve medical imaging. |
Chemistry World September 21, 2010 Hayley Birch |
Self-pumping membrane mimics cell machinery US researchers have imitated the transport functions of biological membranes by incorporating tiny pumps into synthetic membranes. They say their 'self-pumping' mimics could be used in compartment-less fuel cells. |
Chemistry World February 19, 2009 Nina Notman |
Nanoparticles give cancer drug a boost US scientists have taken a novel step towards fighting the reoccurrence of lung cancer, using drug delivering nanoparticles. |
Reactive Reports Issue 56 Jeffrey Krise |
A Basic Approach to Chemotherapy Chemists have found a way to attack malignant cells with an anticancer drug, while sparing healthy cells. |
Chemistry World June 15, 2007 Lionel Milgrom |
Electrochemical Screening for Anti-Cancer Drugs A test that predicts an individual cancer patient's response to different drugs is about to enter clinical trials, developers have announced. The chances of successful treatment will increase, they predict, while costs will decrease. |
Chemistry World September 1, 2008 James Mitchell Crow |
Drug discovery on a chip Scientists in the US have, for the first time, used microfluidics to discover drug leads. The team's lab-on-a-chip device revealed inhibitors of a key membrane-bound protein in hepatitis C virus |
HHMI Bulletin February 2011 Sarah C.P. Williams |
Enforcing Order Changing the spatial arrangement of molecules in a cell can alter their functions. |
The Motley Fool September 26, 2007 Brian Orelli |
4 Platform Drugmakers to Watch Platform drugmakers have the potential to develop multiple drugs for a company. Let's take a look at four companies with good prospects: Abraxis BioScience... DURECT... Halozyme... Flamel Technologies... |
Technology Research News July 27, 2005 |
Baited molecule fights cancer Many teams of researchers are working on ways to use nanotechnology to deliver anticancer drugs directly to cancerous tissue. |
Chemistry World November 12, 2009 Hayley Birch |
New drug design looks top Notch against cancer A new type of drug that can block the switching on of certain genes in cancer cells has shown promise in mice. |
Chemistry World October 15, 2008 Simon Hadlington |
Long-life light illuminates cells The new dye, based on platinum, will carry on emitting light long after any interfering 'autofluorescence' from naturally occurring molecules in the cell has fizzled out. |
Chemistry World August 2, 2011 Kate McAlpine |
Hacking into chemical cell phone calls US researchers have made a nanodevice that can eavesdrop on a cell's mutterings, and they say it could be adapted to listen in on conversations between cells. |
Chemistry World September 22, 2011 Erica Wise |
Faster acting drugs Ionic liquid drugs can rapidly pass through the skin and may open the way to new, more effective medicines, say scientists in Australia. |
Chemistry World January 17, 2008 Lewis Brindley |
Nanomachines to Treat Cancer Scientists at the University of California-Los Angeles (UCLA) have signed a deal with a private investment firm to develop and market 'nanomachines' to treat cancer. |
Chemistry World July 11, 2008 Manisha Lalloo |
Side-effects study opens up new drug leads Existing drugs could be used to treat a broader range of diseases, according to scientists in Germany and Denmark, who have predicted drug targets by using side-effects data on medication labels. |
Chemistry World July 6, 2007 Michael Gross |
Predicting How Proteins Fold Researchers in Italy and the UK have now developed a computational approach that can simulate the folding of membrane proteins in atomic detail. |
Chemistry World October 11, 2007 Jonathan Edwards |
'Tuneable' Polymer Can Separate Anything An international team of scientists have made a polymer with pores which can be fine-tuned to speedily separate different small molecules -- with applications ranging from carbon capture to fuel cells. |
Chemistry World January 4, 2007 Henry Nicholls |
Microscopic Lab Investigates Contents of a Cell It's small-scale science that could have a massive impact on research into cell biology. Scientists have produced a microscopic laboratory where they can count individual proteins in a single cell. |
Chemistry World February 13, 2006 |
Nanoparticles Detect Cell Suicide Plans Researchers have developed a nanotechnological assay for detecting programmed cell death. The technique is effective in cell cultures, they report, and might eventually be used in humans. |