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HHMI Bulletin
May 2010
Sarah C.P. Williams |
Lab-Grown Liver New cell culture system solves problem of growing liver cells.   |
HHMI Bulletin
Winter 2013
Jennifer Michalowski |
A Happy Oasis The usually tranquil space of HHMI investigator Sangeeta Bhatia's office at the Massachusetts Institute of Technology fills with energy as her team gathers in two groups -- liver researchers first, then the cancer team. |
Scientific American
January 2009
Charles Q. Choi |
Do White Blood Cells Make Cancer Deadly? The ability to spread underlies the killing power of cancer. The process occurs, John Pawelek thinks, when tumor cells fuse with white blood cells -- an idea that, if right, could yield new therapies |
Chemistry World
October 23, 2011
David Bradley |
Clicking Together Cultural Niches Researchers in the US have made three-dimensional hydrogels that are not only compatible with living cells but can be tuned to create specialist growing environments - culture niches - for studying cell function. |
Chemistry World
March 10, 2011
Elinor Richards |
3D model to study breast cancer Scientists from the US have made a computational model of the formation of breast acini, the sac-like part of the milk-producing glands, to understand complex events occurring during the progression of breast cancer. |
HHMI Bulletin
May 2011
Jim Schnabel |
Oxygen on the Brain An ancient cellular program to protect cells when oxygen is low seems crucial for the production of new brain cells. |
Scientific American
December 2008
Tim Hornyak |
Turning Back the Cellular Clock: A Farewell to Embryonic Stem Cells? Shinya Yamanaka discovered how to revert adult cells to an embryonic state. These induced pluripotent stem cells might soon supplant their embryonic cousins in therapeutic promise |
HHMI Bulletin
May 2012
Elise Lamar |
Cells on the Move The biochemical signals that set cells on a journey are as diverse as the tissues they move through, but the engine is driven by constant remodeling of a protein network built from a box of cellular Legos. |
Chemistry World
July 1, 2012
Mellisae Fellet |
3D printed sugar network to feed engineered organs US researchers can build vessels into a cell-containing gel -- the beginnings of a thick tissue. Scientists form the gel around a lattice of printed sugar fibers. The fibers dissolve after the gel sets, leaving a network of channels that carry nutrients like blood vessels. |
IEEE Spectrum
August 2006
Schoenbach et al. |
Zap Extreme voltage could be a surprisingly delicate tool in the fight against cancer. The list of effects that scientists have achieved using nanoseconds-long pulses is growing rapidly, though their actual use as a medical treatment is still years away. |
Chemistry World
April 2, 2009
Michael Gross |
Light-guided hydrogels direct cell growth Researchers in the US have developed a gel-like material whose structural and chemical properties can change in response to laser light |
The Motley Fool
November 9, 2004
Charly Travers |
Are Stem Cells a Rule Breaker? Does the science offer real hope or just hype? Biotech investors take on enough risk in the normal course of drug development that they do not need to worry about whether or not the underlying technology even works. |
HHMI Bulletin
Aug 2011
Cassandra Willyard |
A Faster Knockout With a virus, a needle, and an ultrasound machine, researchers have drastically cut the time it takes to disable a gene in mice. |
Popular Mechanics
November 27, 2007
Alex Hutchinson |
Stem Cells 2.0: Beyond the Hype, Engineers Look to Build Fast Engineers play the important role of making lab bench discoveries reproducible and efficient for use in industry. |
HHMI Bulletin
May 2010
Sarah C.P. Williams |
Young Again Niche cells can reverse the aging of stem cells. |
HHMI Bulletin
May 2012
Alexander Gelfand |
Sticky-Fingered Culprit Researchers are discovering how the blood's wound-healing platelets have a hand in metastasis as well. |
Scientific American
January 17, 2007
Charles Q. Choi |
A Stroke for Stem Cells The brain becomes a target in stem cell clinical trials. |
National Defense
March 2008
Grace V. Jean |
Creating the Body's Microenvironment to Grow Artificial Organs Scientists are using micro-electromechanical systems to grow artificial organs. |
The Motley Fool
November 28, 2007
Brian Orelli |
Stem Your Expectations of Stem-Cell Discoveries Making "stem" cells out of skin cells isn't all it's cracked up to be. The recent discovery has a long way to go before it can catch up to the research currently being done with stem cells. |
HHMI Bulletin
Aug 2011
Sarah C.P. Williams |
The Goldilocks of Cells Too much or too little cell death can lead to disease. Scientists are learning how to find the range that's just right. |
HHMI Bulletin
Aug 2011
Richard Saltus |
T-Cell Booster Kits A bioengineer remodels cell surfaces to prod the immune system. |
HHMI Bulletin
May 2010 |
A Kaleidoscopic View Elaine Fuchs, head of the Laboratory of Mammalian Cell Biology and Development at Rockefeller University in New York, has managed to pioneer new ways of studying skin and hair and to manipulate stem cell differentiation. |
Technology Research News
June 29, 2005
Eric Smalley |
Cell combo yields blood vessels Researchers experiment with methods of getting blood vessels to grow in replacement organs before the tissue is placed in the body. |
Wired
August 2003
Jennifer Kahn |
The End of Cancer (As we Know it) Diagnosis. Chemotherapy. Radiation. Slow painful death. No more. A new era of cancer treatment is dawning. Meet three scientists who are using the revelations of the Human Genome Project to reshape medicine. |
The Motley Fool
August 31, 2007
Brian Orelli |
A Stem-Cell Primer Public funding from states could help companies doing stem cell research. Read about Geron, StemCells, Osiris Therapeutics, ViaCell and Invitrogen, companies that may profit from the increased public spending. |
BusinessWeek
June 13, 2005
Catherine Arnst |
Biotech, Finally The past 30 years of biological discoveries, insights into the human genome, and exotic chemical manipulation have unleashed a wave of biological drugs, many of them reengineered human proteins. |
Chemistry World
August 19, 2009
Phillip Broadwith |
Antioxidants could promote cancer Some tumor cells can actually use antioxidants to protect themselves from natural cellular defense mechanisms, enabling them to survive and proliferate. |
HHMI Bulletin
Fall 2012
Elise Lamar |
Push and Pull Jennifer Zallen, an HHMI early career scientist at Memorial Sloan-Kettering Cancer Center, studies how embryonic tissues stretch along an anterior-posterior axis using the fruit fly Drosophila melanogaster as a model system. |
Reactive Reports
Issue 64
David Bradley |
Stem to Sperm New research shows that stem cells from human bone marrow can be converted into early-stage sperm. The discovery could lead to novel fertility treatments in the long-term. |
Scientific American
March 2007
Alison Snyder |
Sight for Sore Eyes Having generated a cell source and overcome the safety concerns associated with transplanting stem cells, researchers still face possibly their biggest challenge: showing that the transplanted photoreceptors wire up to other neurons that eventually connect to the optic nerves. |
Chemistry World
November 1, 2013
Megan Tyler |
High-throughput chip for drug screening in 3D A simple micro-array chip developed by scientists in China could sharpen the search for new drugs by enabling the high-throughput screening of drug candidates against cells cultured in three dimensions. |
Wired
November 2003
Jennifer Kahn |
Regrow Your Own Broken heart? No problem. New liver? Coming right up. The road to regeneration starts here. |
Scientific American
September 19, 2005
Charles Q. Choi |
Chatting Up Cells Stem cells can transform into whatever cell the body tells them to. Unfortunately, scientists have yet to master that particular gift of gab. But investigators may soon crack the language with tiny "chat rooms" for stem cells. |
Chemistry World
July 21, 2011
Elinor Richards |
Cell Control to Change Cell Function US scientists can now control the reactions occurring inside cells. |
Chemistry World
April 10, 2008
Sarah Houlton |
Radiotherapy Side-Effects Suppressed A new drug being developed by scientists at Cleveland BioLabs (CBLI) in the US may hold the key to protecting healthy cells from the effects of radiotherapy during cancer treatment. |
BusinessWeek
June 13, 2005
Arlene Weintraub |
A Boost for Broken Hearts? The Institute of Regenerative Medicine in Barbados is convinced that stem cells from fetuses can repair cardiac damage. |
HHMI Bulletin
February 2011
Sarah C.P. Williams |
Releasing the Brakes on Cell Fate Converting one cell type directly into another is a kind of modern-day alchemy, an ultimate goal in biological research. But unlike turning base metals into gold, changing a cell's identity is feasible, new research shows. |
Popular Mechanics
January 28, 2010
Cassie Rodenberg |
Next-Gen Transplant Techniques Can Stop Organ Rejection About 77 organ transplants are performed each day in the U.S., and more than 101,000 people are on a wait list for body parts such as hearts, skin and veins, according to the Mayo Clinic. |
Chemistry World
December 2, 2010
James Urquhart |
Micro organ system to test cancer drugs Japanese researchers have created an organ-on-a-chip system that simultaneously tests how liver, intestine and breast cancer cells respond to cancer drugs. |
Chemistry World
July 28, 2009
Michael Gross |
DNA to direct and switch off chemo Researchers in the US have developed a new approach to cancer chemotherapy using short DNA strands to help target delivery of the drug directly to cancer cells, and 'call it off' should problems arise. |
Chemistry World
September 24, 2015
Andy Extance |
Cosmetics deals push skin 3D bioprinting 3D bioprinting's allure has attracted interest from the skincare industry, with three leading firms each launching skin printing initiatives in mid-2015 that they hope will revolutionize cosmetic testing. |
Chemistry World
April 2010 |
Column: The crucible We are getting better at manipulating cells to grow into the tissues we need. Chemical factors are key, says Philip Ball |
Chemistry World
January 12, 2011
Amaya Camara-Campos |
Artificial intestine for gut studies Three-dimensional hydrogel scaffolds for studying cells under realistic physiological conditions have been made by scientists from the US and Korea to study drug absorption in the gut. |
HHMI Bulletin
Winter 2013
Sarah C.P. Williams |
One Foot in Front of the Other In every type of living cell, materials jet around in a similar variety of manners. The way cellular cargo travels depends on its size, where it's headed, how quickly it must arrive, and how much energy is available. |
BusinessWeek
September 23, 2010
Rob Waters |
Stem Cells That Save Big Pharma a Bundle Drugmakers hope to save big by using stem cells to test drugs for dangerous side effects long before costly human trials are needed. |
Smithsonian
March 2004 |
Signal Discovery? A Los Angeles scientist says living cells may make distinct sounds, which might someday help doctors "hear" diseases |
Chemistry World
January 16, 2014 |
The art of alternatives Recent years have seen great advances in alternatives to animal tests. Yet we still need to understand how and why compounds are toxic before we can make the giant leap to replacement. |
Bio-IT World
July 15, 2003
Julia Boguslavsky |
'Fingerprinting' a Single Cell Single-cell proteomics is finally within reach, thanks to a professor of analytical chemistry. |
IEEE Spectrum
February 2005
Carol Ezzell Webb |
The Body Shops Part human, part machine, replacement organs may one day extend your life |
Reactive Reports
Issue 55
David Bradley |
Testing the Byproducts of Cell Death A new approach to testing whether a particular chemotherapy agent is working well in treating a patient's cancer is being developed by UK scientists |
