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Chemistry World September 30, 2014 Kirsty Muirhead	Mirror peptides hitch a lift into the cell Scientists in the US have developed a method for successfully transporting chemotherapeutic d-peptides into the cell cytosol.
Chemistry World April 8, 2010 Simon Hadlington	Arsenic anticancer target revealed Researchers from China and France believe they have uncovered the molecular mechanism by which arsenic trioxide kills certain cancer cells.
Chemistry World June 2011	Breaking through the barrier Getting drug molecules into the brain means crossing the defensive blood-brain barrier. Anthony King investigates how chemists are infiltrating the brain's fortress
Chemistry World September 10, 2008 Simon Hadlington	Failed anxiety drug could treat cancer Scientists believe they have solved the mystery of how a drug originally developed for treating anxiety can kill cancer cells.
Chemistry World July 28, 2009 Michael Gross	DNA to direct and switch off chemo Researchers in the US have developed a new approach to cancer chemotherapy using short DNA strands to help target delivery of the drug directly to cancer cells, and 'call it off' should problems arise.
Chemistry World October 9, 2011 Simon Hadlington	New probe throws light on cellular lipids Scientists in the US have developed a new sensor that can track and measure lipids in living cells.
Chemistry World July 2010 Hayley Birch	Special Report: Health breakthroughs of the decade New discoveries have been made with cancer vaccines, genomics, statin drugs, allosteric modulators, and RNA interference during the last decade.
Bio-IT World December 15, 2004 Zachary Zimmerman	Silence Is Golden Life Science Insights believes that RNAi therapeutics will dramatically affect the pharmaceutical and healthcare industries, becoming the next major class of therapeutics, joining small molecules, proteins, and monoclonal antibodies.
Chemistry World January 6, 2011 Laura Howes	Using HIV against itself US researchers have developed a 'Trojan horse' molecule that uses HIV to trigger the release of a drug that destroys the virus.
BusinessWeek December 12, 2005 Michael Arndt	Cancer Cells With A Death Wish Is Abbott Labs' Stephen Fesik closing in on a way to make cancer cells self-destruct?
Pharmaceutical Executive July 30, 2007	Tomorrow's Drugs A look at the seven top therapies and technologies vying to deliver the next generation of drugs.
Chemistry World August 7, 2008 Simon Hadlington	RNA stops HIV in its tracks Scientists have successfully used a biochemical Trojan horse to smuggle killer sequences of RNA into immune cells to mug invading HIV, stopping infection in its tracks
HHMI Bulletin February 2011 Sarah C.P. Williams	Enforcing Order Changing the spatial arrangement of molecules in a cell can alter their functions.
The Motley Fool February 9, 2006 Jason Mac Gurn	RNA: Rule Breaker Nucleic Acid Investors, new RNA-based technologies may be the next revolution in biopharmaceuticals. ISIS Pharmaceuticals... Sirna Therapeutics... Alnylam Pharmaceuticals...
The Motley Fool July 20, 2005 Karl Thiel	Pride and Preclinicals Biotech ArQule has surged, but take its early-stage data with a grain of salt.
Chemistry World April 19, 2011 Simon Hadlington	Cell factories package drugs for delivery Scientists in Australia and Germany have used living cells as 'factories' to encapsulate particles such as drugs in biological membranes.
The Motley Fool September 26, 2007 Brian Orelli	4 Platform Drugmakers to Watch Platform drugmakers have the potential to develop multiple drugs for a company. Let's take a look at four companies with good prospects: Abraxis BioScience... DURECT... Halozyme... Flamel Technologies...
BusinessWeek April 12, 2004 John Carey	Gene-Based Therapy: Back To The Couch Recent setbacks show (again) that biotech needs more patience and less ballyhoo
Chemistry World December 21, 2006 Henry Nicholls	Silent SNPs Serve up a Structural Surprise The sequence of amino acids no longer dictates the structure and function of a protein according to a surprising new paper.
BusinessWeek May 24, 2004 Arlene Weintraub	Regenerative Medicine's Slow Start Scientists think proteins that spur the body to heal could make powerful drugs, but harnessing that potential has been tough
Chemistry World December 2007 Derek Lowe	Column: In the Pipeline The challenge of biologics.
Chemistry World December 12, 2013 Jeanne Therese Andres	Kiss-and-run drug delivery Carriers that release hydrophobic substances at cell membranes but do not enter the cells themselves could be the foundation for a new way to deliver drugs into cells, according to a team of scientists in Germany.
Chemistry World July 21, 2011 Elinor Richards	Cell Control to Change Cell Function US scientists can now control the reactions occurring inside cells.
Chemistry World February 2011	Idle cures Taking a coffee break could help find cures for cancer or Aids. Katrina Megget looks at the future of research that harnesses the computing power of the World Community Grid
BusinessWeek November 24, 2003 John Carey	Barring The Door Against AIDS A new generation of drugs focuses on keeping the virus from entering cells.
HHMI Bulletin Aug 2010	Joaquin Espinosa's fresh look at p53 Even though it was discovered more than 25 years ago, and many more tumor suppressor genes have been found since, p53 remains the big one. It's mutated in about 50 percent of tumors.
BusinessWeek June 13, 2005 Catherine Arnst	Biotech, Finally The past 30 years of biological discoveries, insights into the human genome, and exotic chemical manipulation have unleashed a wave of biological drugs, many of them reengineered human proteins.
Pharmaceutical Executive November 1, 2006	Thoughtleader: Making Things Stick Ambrx has created the "glue" that allows researchers to attach activity-enhancing molecules to amino acids where they couldn't before.
The Motley Fool November 2, 2004 Charly Travers	Biotech's 5-Baggers: Part 3 Year after year, the hottest biotech companies with investors are those with drugs in development for the treatment of cancer.
Chemistry World January 4, 2007 Henry Nicholls	Microscopic Lab Investigates Contents of a Cell It's small-scale science that could have a massive impact on research into cell biology. Scientists have produced a microscopic laboratory where they can count individual proteins in a single cell.
Bio-IT World April 16, 2004 Kevin Davies	The Matrix Revolutions Serenex, a company dedicated to drug discovery, uses a proprietary matrix, or affinity media, to bind purine-binding protiens - a process that could transform the drug discovery business.
Chemistry World July 31, 2012 David Bradley	Hydrogels can release drugs one at a time A hydrogel that can be programmed to release different protein drugs one after the other rather than all at once could simplify the delivery of complex therapeutic regimens for various diseases.
Chemistry World February 12, 2014 Manisha Lalloo	Synthetic strategy targets 'undruggable' small RNAs Chemists in the US have found a way to predict small molecules that can target short pieces of RNA involved in some diseases, such as cancer.
Chemistry World November 25, 2009 Simon Hadlington	Virus shells traps multiple proteins Scientists in The Netherlands have devised a way to pack large numbers of proteins into the empty shell of a virus.
Chemistry World April 27, 2007 Ned Stafford	New HIV Blocker Prepares for Trials Scientists who isolated a natural component of human blood that defends against the HIV-1 virus are now moving quickly to test their ideas clinically in the hope of bringing a new class of HIV-blockers based on peptide therapeutics to market.
Reactive Reports Issue 51 David Bradley	Protein Crystals Trapped Researchers have developed a new technique for crystallizing proteins, which could open up a whole range of materials to this powerful analytical technique.
Managed Care November 2003 Thomas Morrow	Making Sense of Antisense and Interference Treatments that interfere with protein synthesis at the cellular level will soon be debated in medical policy committee meetings.
HHMI Bulletin Aug 2010 Richard Saltus	Three-Dimensional Cell Cultures Thinking big but starting small, Sangeeta Bhatia is closing in on her ambitious goal: growing human livers in the lab from scratch.
IEEE Spectrum August 2006 Schoenbach et al.	Zap Extreme voltage could be a surprisingly delicate tool in the fight against cancer. The list of effects that scientists have achieved using nanoseconds-long pulses is growing rapidly, though their actual use as a medical treatment is still years away.
Bio-IT World September 11, 2003 Mark D. Uehling	Fishing Chips The next generation of protein microarrays from the likes of Protometrix and Molecular Staging may threaten the early leads of Biacore and Ciphergen -- and work so well that drug companies won't want them.
Chemistry World January 31, 2008 John Bonner	RNAi Scores Victory Against Crohn's Disease in Mice Thousands of people suffering from the debilitating gut condition Crohn's disease could experience relief from their symptoms through a technique that blocks production of a key protein in the inflammation process.
HHMI Bulletin Spring 2013 Nicole Kresge	A Structural Toolbox Natalie Strynadka wants to design a better antibiotic. Her strategy: learn about the molecules bacteria use to invade cells. Her tool: structural biology.
The Motley Fool July 30, 2007 Brian Orelli	Another Blow to Gene Therapy The FDA shuts down a clinical trial, tripping up Targeted Genetics and possibly its competitors. A subject in the trial of their gene therapy arthritis medication died shortly after taking the drug.
Chemistry World June 2, 2006 Jon Evans	Axons Get Directions Scientists are a step closer to understanding the processes that control the growth and spread of nerve cells, following the discovery of a protein complex that directs the transport of building material to growing axons.
Pharmaceutical Executive October 1, 2008	The other half of an HIV mystery is solved When HIV infects a human immune cell, which of the cell's own genes play a role?
Chemistry World August 12, 2011 Manisha Lalloo	Unraveling cell membranes to understand drugs Researchers in Sweden have found a way to create flattened cell membranes, known as supported lipid bilayers, out of real cell structures.
AskMen.com Jacob Franek	New Cancer Therapies As cancer research explodes, the availability of new and innovative interventions is expanding almost daily.
Chemistry World June 28, 2009 Jon Cartwright	Antimicrobial nanoparticles may help fight brain infections Antimicrobial nanoparticles that can cross the, almost impermeable, blood-brain barrier have been created by Asian researchers.
Chemistry World August 22, 2008 Hayley Birch	Drug uptake rule challenged A study by UK scientists apparently contradicts a 100-year-old rule thought to govern the rate at which molecules cross biological membranes.
Chemistry World November 25, 2013 Carla Pegoraro	Steering cells towards biocomputers Bacterial toxins that undergo unique cell interactions have been used to perform logic functions by researchers in Germany. This innovation will help push the limits of synthetic biology.