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Chemistry World April 19, 2011 Simon Hadlington	Cell factories package drugs for delivery Scientists in Australia and Germany have used living cells as 'factories' to encapsulate particles such as drugs in biological membranes.
Chemistry World October 7, 2010 Simon Hadlington	New light shed on 'photothermal' cell death Photothermal therapy - where tiny particles of a metal are introduced into a cell and heated by laser light to kill the cell - might not work in the way people think, researchers in the UK have discovered.
Chemistry World October 7, 2012 David Bradley	Magnetic nanoparticles zap cancer Nanoparticles can be used as a remote-controlled magnetic death switch to kill cancer cells, according to researchers from Korea.
Chemistry World October 2, 2012 Fiona McKenzie	Protein sorting within cells US scientists have used magnetic nanoparticles with specific ligands to latch on to and visualize specific proteins in living cells.
Chemistry World January 26, 2011 Anna Watson	Channelling deeper to target breast cancer US scientists have developed a model of the breast ductal system that could be used to discover abnormal cells or deliver drugs at locations further along the ducts than other techniques. The model fits on a slide, enabling on-chip experiments.
Chemistry World September 14, 2009 Simon Hadlington	New 'on-off' membrane for drug delivery A team led by Daniel Kohane of Harvard Medical School in Boston, US, harnessed the thermosensitive properties of poly(N-isopropylacrylamide) to form the basis of the new system.
Chemistry World April 7, 2009 Lewis Brindley	Cells get in line Magnetic nanoparticles that 'shepherd' cells into neat lines have been designed by American scientists.
Chemistry World April 11, 2006 Jon Evans	Nanotechnology Tackles Chemotherapy Chemists and medical researchers have developed nanoparticles that target chemotherapy drugs directly at tumours. The researchers claim that the same technique could be used to develop nanoparticle-based treatments for a wide range of other diseases.
Chemistry World March 16, 2009 Hayley Birch	Nanodumbbells Target Cancer Cells US scientists have designed nanoparticles that function like 'guided missiles' in the targeted destruction of breast cancer cells.
Chemistry World November 27, 2007 James Mitchell Crow	A Flare for Gene Silencing US scientists have developed nanoparticle probes coated with DNA that release fluorescent 'flares' when they silence genes inside cells.
HHMI Bulletin Winter 2013 Amber Dance	A Trick of Light When miniSOG protein takes in blue light, it converts ordinary oxygen into a short-lived, excited state called singlet oxygen, which reacts with and changes the molecules around it. The singlet oxygen destroys the mitochondria's delicate machinery.
Chemistry World February 13, 2006	Nanoparticles Detect Cell Suicide Plans Researchers have developed a nanotechnological assay for detecting programmed cell death. The technique is effective in cell cultures, they report, and might eventually be used in humans.
Chemistry World February 4, 2011 Harriet Brewerton	Transplant tracking Magnetic nanoparticles could be used to track neural stem cells after a transplant in order to monitor how the cells heal spinal injuries, say UK scientists.
Chemistry World September 7, 2008 Simon Hadlington	Coupled proteins to reveal drug hits Researchers in France have successfully attached an 'electrical switch' to a key class of membrane proteins targeted by many drugs.
Chemistry World September 1, 2011 Josh Howgego	Small molecules open gates to the brain New tools have been developed which make it possible to chemically shut down nerve cells in the brain at will and study the effects on behavior. The tools - modified ion channels - mean the causal relationship between individual nerves and behavior can be directly studied.
Chemistry World March 9, 2011 Simon Hadlington	Chemical mystery of antifungal compound solved US researchers have applied synthetic organic chemistry to crack a mystery that has baffled scientists for more than 50 years: how the powerful, naturally occurring antifungal compound amphotericin B interacts with sterols in cell membranes.
Chemistry World July 21, 2011 Elinor Richards	Cell Control to Change Cell Function US scientists can now control the reactions occurring inside cells.
Chemistry World September 23, 2008 Simon Hadlington	Nanoparticles Hide Behind Protein Cloak Polymer nanoparticles suspended in human blood become cloaked in plasma proteins, new research has shown.
Chemistry World January 10, 2008 Simon Hadlington	Proton Joins Elite Club of Cellular Messengers Researchers have discovered a new chemical that carries messages rapidly between cells - the first for more than 20 years. But unlike conventional signalling molecules, this is a far simpler chemical entity: it is the humble proton.
Chemistry World March 6, 2006 Jon Evans	Nanoprobes Light up Cellular Demolition Researchers have developed a method for detecting and imaging programmed cell death (apoptosis). The method, involving polymer nanoparticles, could be used to diagnose apoptosis-related diseases and inform drug development.
Chemistry World March 20, 2009 Jon Cartwright	Medical Probes Get Easy to Spot Scientists in the US have created nano-scale medical probes that are visible via both magnetic resonance imaging (MRI) and optical microscopy.
Chemistry World March 21, 2010 Simon Hadlington	Nanoparticles successfully deliver RNA interference in cancer patients The system aims to exploit the phenomenon of RNA interference, where short sequences of double-stranded RNA, called small interfering RNA or siRNA, can trigger the disruption of the manufacture of certain proteins in a cell.
Chemistry World September 21, 2010 Hayley Birch	Self-pumping membrane mimics cell machinery US researchers have imitated the transport functions of biological membranes by incorporating tiny pumps into synthetic membranes. They say their 'self-pumping' mimics could be used in compartment-less fuel cells.
Chemistry World July 17, 2012 Harriet Brewerton	Pinning down cancer US scientists have synthesized pin-shaped nanoparticles with magnetic and optical properties. The nanoparticles could be used for magnetic resonance imaging, early detection and photothermal therapy of cancer and other diseases.
Chemistry World July 20, 2011 Josh Howgego	Magnets turn up the heat on tumours Claims that magnets can cure cancer might sound like quackery. But French researchers have harnessed iron oxide structures from bacteria to selectively kill tumour cells using an alternating magnetic field.
Chemistry World March 9, 2009 Lewis Brindley	Finding the Risks of Nanoparticle Exposure A new model for nanoparticle exposure should provide more realistic insights into the possible health risks of airborne nanoparticles, researchers in Switzerland claim.
Chemistry World May 13, 2009 Lewis Brindley	Combination nanoparticles to fight cancer Korean chemists have assembled a multitalented nanoparticle that can hunt down, treat, and illuminate cancerous cells.
Chemistry World July 25, 2013 Rowan Frame	Nanomagnets clean blood Nanoparticles that never have to enter the body can capture harmful components in blood, scientists in Switzerland have shown.
Technology Research News October 20, 2004	Biochip levitates droplets Researchers have devised a way to magnetically levitate particles and droplets that have volumes smaller than one billionth of a milliliter. Labs-on-a-chip is one of many potential uses.
Chemistry World July 2, 2007 Michael Gross	Transistor tuned to ion channel As living cells can detect many compounds with high sensitivity via receptors on their membranes, researchers are keen to exploit them in electronic biosensors. Researchers in Germany now report the feasibility of just such a receptor-cell-transistor biosensor.
Chemistry World February 12, 2012 Jon Cartwright	Nanoparticles slow iron absorption in the gut Nanoparticles used in food and pharmaceuticals could have unintended physiological effects.
Technology Research News July 30, 2003	See-through magnets hang tough Researchers from the Independent University of Barcelona (UAB) and the University of Zaragoza in Spain have found a way to form transparent, durable, lightweight magnets that maintain their magnetism in magnetic fields and high temperatures.
Chemistry World December 13, 2010 James Urquhart	Nanotube probe for cellular studies A new way of peering inside biological cells using carbon nanotubes as tiny multifunctional endoscopes has been developed by US researchers.
Chemistry World June 19, 2012 Anthony King	Nanoparticles linked to rheumatoid arthritis Three types of nanoparticles were found to ramp up protein citrullination in cell cultures, a change that can make the body think native proteins are foreign. This process has previously been linked to autoimmune disease.
Chemistry World May 30, 2006 Michael Gross	A Physiological Role for Healthy Prions Researchers have shown that the healthy version of the scrapie pathogen helps maintain the optimum concentration of copper ions in the cell.
Chemistry World July 28, 2009 Michael Gross	DNA to direct and switch off chemo Researchers in the US have developed a new approach to cancer chemotherapy using short DNA strands to help target delivery of the drug directly to cancer cells, and 'call it off' should problems arise.
Chemistry World February 28, 2006 Jon Evans	Magnetic Appeal of Shape-Change Polymer Polymer scientists developed polymers that change shape in response to a magnetic field by incorporating magnetic iron(III)oxide nanoparticles into a shape-memory polyetherurethane compound known as TFX.
Technology Research News January 29, 2003 Kimberly Patch	Tiny hole guides atoms against tide Researchers in Poland have made a synthetic device that uses an electrical field and an extremely small, conical pore in a thin film of material to coax potassium ions through the artificial membrane against their electrochemical potential.
Chemistry World January 17, 2011 Laura Howes	Nanoparticle divides to conquer Scientists have made a nanoparticle that breaks up into smaller units once it reaches its target, allowing it to penetrate deeper into tumour tissue and deliver treatment more effectively.
Technology Research News July 27, 2005	Baited molecule fights cancer Many teams of researchers are working on ways to use nanotechnology to deliver anticancer drugs directly to cancerous tissue.
Chemistry World November 25, 2013 Carla Pegoraro	Steering cells towards biocomputers Bacterial toxins that undergo unique cell interactions have been used to perform logic functions by researchers in Germany. This innovation will help push the limits of synthetic biology.
HHMI Bulletin May 2012 Nicole Kresge	Better Than a Straitjacket Scientist Sandhya P. Koushika devised an inexpensive, simple way to get the worms to pause so she can image cellular activity in the transparent creatures.
Technology Research News July 13, 2005	Magnetics Drives Particle Patterns Researchers have devised a way to use electric and magnetic fields to assemble magnetic microparticles into a wide variety of patterns, including clusters, rings, chains and networks.
Chemistry World May 9, 2008 Simon Hadlington	All-in-one gene detection on a chip Scientists in Singapore have invented a tiny machine that can rapidly prepare, purify and genetically analyse blood or other biological samples in less than 20 minutes.
Technology Research News September 22, 2004	Virus Forms Nano Template Living matter self-assembles into complex organisms that can contain billions of cells, and researchers have tapped biological molecules like DNA and viruses to self-assemble technologically useful structures and materials.
Chemistry World July 7, 2011 Hayley Birch	Could Life Have Emerged Inside Inorganic Shells? The basic components of cells can operate within the bounds of inorganic membranes made from nanoparticles, a new study shows.
Chemistry World February 9, 2009 Phillip Broadwith	Molecular thermometer takes cell temperature A fluorescent polymer that can accurately measure the temperature inside living cells has been invented by researchers in Japan.
Chemistry World June 9, 2008 Simon Hadlington	Artificial virus silences genes Scientists in Korea have created an artificial virus that can target the nucleus of cancer cells and knock out specific genes.
Chemistry World October 21, 2013 Helen Bache	Sustainable materials sound good Cellulose fibers covered with magnetic nanoparticles have been used to make ultrathin loudspeakers by researchers in Sweden. The material could provide a cheaper and more sustainable alternative to the polymers traditionally used in speakers.
Technology Research News December 1, 2004	Smart Dust Gets Magnetic One of the main challenges in making labs-on-a-chip is finding ways to control and mix tiny amounts of liquids. Researchers are using minuscule silicon particles to carry out these tasks.