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Chemistry World
October 27, 2014
Tim Wogan
Folding rules used to build unnatural proteins Scientists in the UK and US have designed and synthesized unnatural protein structures, using theoretical calculations to explore the factors affecting protein folding and stability. mark for My Articles similar articles
Chemistry World
June 1, 2012
Simon Hadlington
Protein architecture with atomic precision Researchers have made a key breakthrough in designing and building geometrically defined nanostructures from proteins with unprecedented accuracy. mark for My Articles similar articles
Chemistry World
November 13, 2014
Katrina Kramer
Persuading proteins to form porous polyhedra Researchers in the US have designed a hollow cube out of naturally occurring proteins, something that was previously only possible with DNA. mark for My Articles similar articles
Bio-IT World
June 12, 2002
Karen Hopkin
Computational Biologists Join the Fold CASP5 competitors compare the best algorithms for modeling the 3-D structure of proteins -- an exercise that could lead to new insights into the pathogenesis and treatment of disease. mark for My Articles similar articles
Chemistry World
February 3, 2013
Andy Extance
Enzyme draws nanopore protein sequencing nearer US scientists at the University of California, Santa Cruz, have made a key step towards nanopore protein sequencing, thanks to an 'unfoldase' enzyme. Mark Akeson's team exploited this enzyme to unravel proteins and pull them through nanopores. mark for My Articles similar articles
Chemistry World
April 14, 2011
Laura Howes
DNA origami yields tiny flask A US group of researchers has made a round bottomed flask from folded up DNA with an internal capacity of just 24000nm 3, which would be enough to hold 800,000 molecules of water. mark for My Articles similar articles
Bio-IT World
June 12, 2002
Mark D. Uehling
Putting Proteins in Their Place Will a 'periodic table' of proteins help classify the ungainly beasts? mark for My Articles similar articles
Chemistry World
November 2006
Philip Ball
Opinion: The Crucible Here are some of the latest instalments in the ongoing story of how protein misfolding causes neurodegenerative diseases -- a story that is not solely about developing clinical treatments or preventative medicines, but which goes to the heart of proteins' role as the stuff of life. mark for My Articles similar articles
Chemistry World
November 27, 2013
Jennifer Newton
A cytochrome from scratch Artificial proteins could be closer to participating in natural biochemical pathways after researchers show that bacteria will process amino acid sequences entirely unrelated to any natural protein to produce a fully functioning cytochrome. mark for My Articles similar articles
Chemistry World
April 2009
Philip Ball
Column: The crucible Unwinding protein fibrils could give a glimpse of how peptides survived on early Earth mark for My Articles similar articles
Technology Research News
March 24, 2004
DNA has nano building in hand Researchers from Ludwig Maximilians University in Germany have built a simple molecular machine from DNA that can bind to and release single molecules of a specific type of protein. mark for My Articles similar articles
HHMI Bulletin
February 2011
Michele Solis
Right Before Your Eyes Coupling protein sequence to function, thousands of variants at a time. mark for My Articles similar articles
Chemistry World
January 19, 2011
Jon Cartwright
Modified protein binders give shortcut to drugs The method, which involves attaching polypeptides to the binders, could help reduce the work required to develop protein binders into safer drugs. mark for My Articles similar articles
Chemistry World
August 26, 2014
Andy Extance
No-frills coats set a trend for designer viruses Dutch scientists have built a simple model of viruses' protective coats in an attempt to create viral mimics that could fight diseases, as opposed to causing them. mark for My Articles similar articles
Bio-IT World
October 10, 2003
Jeffrey Skolnick
Protein Structure Prediction in Drug Discovery Indications are that structure prediction can assist in the automated assignment of proteins to known pathways. mark for My Articles similar articles
Chemistry World
August 6, 2009
Hayley Birch
Nanoscale tools from DNA origami US scientists have demonstrated a nanoconstruction approach that allows the creation of self-assembling DNA 'origami' folded in an array of different shapes, from bent rods to toothed gears. This opens new possibilities for engineering nanoscale tools and devices. mark for My Articles similar articles
Chemistry World
October 27, 2006
Richard Van Noorden
Synthetic Origami Folds Like Natural Enzymes Researchers have synthesised a large organic molecule that folds up like a small protein, though its backbone is entirely non-biological. The achievement is a step along the path to producing truly synthetic enzymes in the laboratory. mark for My Articles similar articles
Chemistry World
February 13, 2014
Philip Ball
Ice core to antifreeze protein's inner workings The antifreeze protein that protects the winter flounder from sub-zero temperatures has been found to have an odd structure. mark for My Articles similar articles
Chemistry World
January 21, 2011
David Barden
Close encounter makes modifying proteins easy Chemists in the US have now developed a powerful strategy for selectively modifying the side-chains of proteins, which they hope will enable the creation of new tools to investigate protein interactions involved in human diseases. mark for My Articles similar articles
Chemistry World
November 29, 2012
David Bradley
Lego-like DNA bricks are child's play DNA building blocks have been pieced together to form a multitude of Lego-like bricks by researchers at Harvard University and Massachusetts Institute of Technology in the US. mark for My Articles similar articles
Reactive Reports
Apr/May 2005
David Bradley
At Last, the Structure of DNA Researchers have made a significant advance in our understanding of life's main molecule, using X-ray crystallography to determine the three-dimensional structures of nearly all the possible sequences of a macromolecule. mark for My Articles similar articles
Chemistry World
April 27, 2006
`Sticky Trees' Glue Molecules to Proteins Researchers have developed a chemical glue that binds molecules to proteins without compromising protein function. The method could be used to modify a wide range of proteins for a variety of purposes, such as in the development of new protein-based therapies. mark for My Articles similar articles
Chemistry World
June 25, 2013
Michael Gross
A foaming protein from the horse's mouth Researchers in the UK have solved the structure of this protein, yielding tantalizing hints to a novel kind of surface activity and to evolutionary connections to other examples. mark for My Articles similar articles
Chemistry World
September 29, 2010
Hayley Birch
Protein folding: knotted or not A new study may help scientists unravel the complex problem of protein folding. The study suggests knotted proteins, which present a particular challenge to folding experts, could be untied with a couple of well-targeted tugs. mark for My Articles similar articles
Wired
John Bohannon
Gamers Unravel the Secret Life of Protein A look at the protein chemistry world's biennial World Series, a competition to see who can predict the shape a protein will fold into, knowing nothing more than the sequence of its constituent parts. mark for My Articles similar articles
Chemistry World
August 26, 2008
Fred Campbell
High-throughput protein microarrays on the way A new method to rapidly generate protein microarrays has been developed by UK researchers at the University of Manchester. mark for My Articles similar articles
Chemistry World
September 17, 2012
Ian Le Guillou
Raising the curtain on single-stranded DNA Scientists have created microfluidic devices containing single-stranded DNA 'curtains' for the first time, allowing scientists to study its interactions with proteins in real time. mark for My Articles similar articles
Chemistry World
February 7, 2007
Bea Perks
Protein's Non-Natural Alternative Beta peptides are of interest because of what they can tell researchers about protein folding in general. Now, chemical biologists have built what they say is a 'remarkably protein like' structure from beta peptides. mark for My Articles similar articles
Chemistry World
January 2012
DNA motors on With the relentless rise of DNA nanotechnology's popularity, Emma Davies explores the role chemistry has played in its success mark for My Articles similar articles
Chemistry World
December 21, 2006
Henry Nicholls
Silent SNPs Serve up a Structural Surprise The sequence of amino acids no longer dictates the structure and function of a protein according to a surprising new paper. mark for My Articles similar articles
Chemistry World
October 9, 2014
James Urquhart
Designer nanoparticles cast in DNA molds German researchers have developed a DNA origami approach to produce custom-made inorganic nanoparticles with programmable, pre-designed shapes. mark for My Articles similar articles
Chemistry World
February 3, 2010
Lewis Brindley
DNA origami goes large US researchers have found a way to scale up DNA origami into larger structures by using 'tiles' instead of 'staples' to pin them in place. mark for My Articles similar articles
Industrial Physicist Biomimetic Nanotechnology Although biomimetic nanotechnology is in its infancy, with no applications yet reaching commercialization, the barriers in some cases lie mainly in scaling up production processes to industrial levels. mark for My Articles similar articles
Chemistry World
February 28, 2010
Jon Cartwright
Reactions on DNA origami watched with AFM Chemists in Denmark have for the first time imaged chemical reactions on a DNA origami scaffold so that they can precisely attach single molecules, involving atomic force microscopy. mark for My Articles similar articles
Reactive Reports
Issue 51
David Bradley
Protein Crystals Trapped Researchers have developed a new technique for crystallizing proteins, which could open up a whole range of materials to this powerful analytical technique. mark for My Articles similar articles
Prepared Foods
February 2008
Sharon Book
Article: Protein Ingredients for Health and Texture A variety of soy, dairy and egg proteins are available for the food formulator to obtain the desired texture in a food or beverage. mark for My Articles similar articles
Chemistry World
June 6, 2010
Philip Ball
Blood-like liquid protein formed A liquid form of the oxygen-binding protein myoglobin retains its biological function even though it seems virtually water-free, researchers have found. mark for My Articles similar articles
Bio-IT World
November 19, 2004
Spruill & Coulter
Intellectual Property: Following Festo Considered one of the most important patent decisions in history, the Supreme Court's Festo ruling has great significance for biotech inventions. mark for My Articles similar articles
HHMI Bulletin
Feb 2011
DNA Curtains How proteins behave in such a crash test gives scientists data about their structural integrity, how they attach to DNA, and how they behave in a cell. mark for My Articles similar articles
Chemistry World
October 8, 2008
Sarah Houlton
Artificial protein chemistry licensed to industry UK researchers are licensing to industry their method of making artificial proteins by chemically modifying individual amino acid structures. mark for My Articles similar articles
Chemistry World
November 17, 2010
Jon Cartwright
DNA origami meets low-cost lithography Chemists in the US have developed an easy way to integrate the 'bottom up' assembly of DNA origami with the 'top down' patterning of low cost lithography. mark for My Articles similar articles
Chemistry World
December 23, 2015
Bones of contention Can protein in dinosaur bones survive for millions of years? Rachel Brazil explores the evidence. mark for My Articles similar articles
Chemistry World
July 6, 2007
Michael Gross
Predicting How Proteins Fold Researchers in Italy and the UK have now developed a computational approach that can simulate the folding of membrane proteins in atomic detail. mark for My Articles similar articles
Bio-IT World
December 10, 2002
Kevin Davies
Do Try This @ Home In the most impressive sign of distributed computing's awesome potential in biology thus far -- at least in peer-review literature -- researchers have simulated the folding of a mini-protein on a microsecond timescale. mark for My Articles similar articles
Science News
October 14, 2006
Ivars Peterson
Knots in Proteins Knotted proteins are rare, but more than just random occurrences. The secret of spontaneous knotting lies in the mathematics of self-avoiding random walks. mark for My Articles similar articles
Wired
July 2001
Oliver Morton
Gene Machine IBM took a dare: Build a supercomputer that predicts the invisible process of protein folding. Spend $100 million, increase processing speed 100-fold, and revolutionize the field. Then convince the biologists it matters... mark for My Articles similar articles
Chemistry World
June 2009
Michael Gross
Bubble-wrapped frogs Tropical frogs create remarkable protein foams to protect their spawn. Exploration of the underlying chemistry has only just begun mark for My Articles similar articles
HHMI Bulletin
Winter 2013
Nicole Kresge
A Structural Revolution Over the years, scientists and artists have used an assortment of techniques to showcase molecular structure. mark for My Articles similar articles
Chemistry World
July 26, 2007
Richard Van Noorden
Shortcut Protein Synthesis Ditches Amino Acids Chinese chemists have demonstrated a speedy way to make polypeptides by avoiding the costly tedium of linking together amino acids. mark for My Articles similar articles
Technology Research News
December 3, 2003
Kimberly Patch
DNA assembles nanotube transistor Scientists have caused a transistor to self-assemble from a test tube concoction of DNA, proteins, antibodies, carbon nanotubes and minuscule specks of silver and gold. The feat shows that it is possible to assemble the smallest of machines and electronic devices by harnessing DNA's properties. mark for My Articles similar articles