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Chemistry World December 18, 2012 Jennifer Newton |
Technique to measure chemotherapy effectiveness A technique to measure how effective chemotherapy is by studying the physical changes that occur in human cells has been developed by US scientists. |
Chemistry World May 12, 2014 David Bradley |
Elemental discoveries at the cellular level A combination of two high-power analytical techniques -- synchrotron radiation microscopy and atomic force microscopy -- has allowed Italy scientists to map vital elements in a single cancer cell. |
Chemistry World February 11, 2013 Helen Potter |
A new system for cancer detection Cancer cells have been found to differ from normal cells in several ways, including the make up of their cell membranes. Cancer-cell membranes have been found to contain more anionic lipids than normal cells, leading to an overall negatively charged cell surface. |
Technology Research News February 9, 2005 Eric Smalley |
Atomic scopes eye living tissue Researchers have used a scanning probe microscope to look at the structure of a butterfly's wing at a resolution of five nanometers -- just two and a half times the width of DNA molecule -- proving that it is possible to use these microscopes to analyze material from living systems. |
Bio-IT World July 15, 2003 Julia Boguslavsky |
'Fingerprinting' a Single Cell Single-cell proteomics is finally within reach, thanks to a professor of analytical chemistry. |
Smithsonian March 2004 |
Signal Discovery? A Los Angeles scientist says living cells may make distinct sounds, which might someday help doctors "hear" diseases |
Chemistry World July 31, 2012 Fiona McKenzie |
Sorting the good from the bad US scientists have found a way to separate cancerous cells from healthy cells by taking advantage of their adhesion properties. Separating cancer cells for analysis is a critical step for determining the recommended course of treatment for patients. |
Chemistry World July 21, 2011 Elinor Richards |
Cell Control to Change Cell Function US scientists can now control the reactions occurring inside cells. |
Chemistry World January 4, 2007 Henry Nicholls |
Microscopic Lab Investigates Contents of a Cell It's small-scale science that could have a massive impact on research into cell biology. Scientists have produced a microscopic laboratory where they can count individual proteins in a single cell. |
Bio-IT World July 2005 David M. Evans |
Cellular Imaging Takes Drug Discovery to New Heights The potential applications and ultimate value of high-content screening (HCS) and cellular image analysis are limited only by the imagination and expertise of the drug discovery groups using them to probe gene function and cell behavior. |
Chemistry World January 11, 2008 John Bonner |
DNA Nanoparticles Detect Gene Expression US scientists have made nanoparticles from DNA that they say could be used to identify the genes being expressed in a single cell. |
Chemistry World February 28, 2012 Nina Notman |
Observing Charge Distribution in Molecules The distribution of charge across a single molecule has been imaged for the first time by Swiss scientists. It is hoped that this work may eventually lead to electronic devices consisting of organic molecules. |
Reactive Reports November 2005 David Bradley |
Water, Water How a strand of water just a few molecules thick could provide nanoscale clues about water's intriguing properties and why water is the dread enemy of atomic force microscopy. |
Chemistry World August 27, 2015 Matthew Gunther |
Nanoscale microscopy casts light on cellular dynamics Scientists at the Howard Hughes Medical Institute, US, have fine tuned an off-shoot of their super-resolution microscopy technique to image dynamic processes within the cell membrane for the first time. |
Industrial Physicist Jennifer Ouellette |
Seeing with Sound Acoustic microscopy is making inroads into areas such as materials characterization, biology, and medical diagnosis, and giving researchers yet another valuable tool in their imaging arsenal. |
Chemistry World August 13, 2009 Simon Hadlington |
Forcing enzyme activity New research has shown that physically stretching an enzyme can trigger its activity - even when the active site is not hidden in a 'cryptic' position. Mechanical force may play a more important role in biological molecular systems than previously realized. |
Chemistry World August 27, 2015 Jon Cartwright |
AFM pictures show bond polarity Researchers in Germany and the Czech Republic have improved the clarity of atomic force microscopy to probe the distribution of charges within atoms and molecules. |
Chemistry World October 8, 2014 |
Super-resolution light microscopy wins chemistry Nobel The 2014 chemistry Nobel prize has been given to three pioneers of biomedical imaging, whose work has enabled nanoscale features within cells to be captured in exquisite detail. |
Chemistry World August 13, 2010 James Urquhart |
Zooming in on intermolecular bonds German researchers have captured clear images of intermolecular bonds for the first time using a modified form of scanning tunnelling microscopy. |
Chemistry World August 2, 2011 Kate McAlpine |
Hacking into chemical cell phone calls US researchers have made a nanodevice that can eavesdrop on a cell's mutterings, and they say it could be adapted to listen in on conversations between cells. |
Chemistry World March 31, 2009 Lewis Brindley |
Giving molecules a stretch A simple way to stretch small molecules and measure the forces at play has been developed by researchers in the US. |
Chemistry World October 23, 2014 |
The resolution revolution Super-resolution fluorescence microscopy earned three of its creators a Nobel prize this year. |
Chemistry World November 5, 2013 |
A close look at microscopy Atomic force microscopy is widely used in materials science and is beginning to be adopted in life science too. |
HHMI Bulletin February 2011 Sarah C.P. Williams |
Releasing the Brakes on Cell Fate Converting one cell type directly into another is a kind of modern-day alchemy, an ultimate goal in biological research. But unlike turning base metals into gold, changing a cell's identity is feasible, new research shows. |
Bio-IT World December 15, 2003 Malorye A. Branca |
Scenes from a Cell Breakthroughs are making cell-based screening faster, easier, more powerful. |
Chemistry World March 10, 2011 Elinor Richards |
3D model to study breast cancer Scientists from the US have made a computational model of the formation of breast acini, the sac-like part of the milk-producing glands, to understand complex events occurring during the progression of breast cancer. |
Chemistry World December 8, 2015 Liisa Niitsoo |
A sound idea for treating lung disease Scientists in Australia have made a portable device that gently vibrates stem cells with sound waves to turn them into an aerosol. The system could be an effective route for treating various pulmonary diseases. |
Chemistry World October 7, 2012 David Bradley |
Magnetic nanoparticles zap cancer Nanoparticles can be used as a remote-controlled magnetic death switch to kill cancer cells, according to researchers from Korea. |
Bio-IT World January 21, 2005 Mark D. Uehling |
Profiling Drugs via Microscopy With robotic equipment, this Harvard team scans cells faster than researchers can blink their eyes. |
Chemistry World August 15, 2007 John Bonner |
Chemists Claim Biological Alchemy South Korean chemists say they have turned muscle cells from the sole of a human foot into something akin to stem cells, using a simple molecule called neurodazine. |
Chemistry World April 24, 2013 Helen Bache |
3D microfluidic liver on a chip Researchers have developed a three-dimensional liver model that can recreate cell signalling within the organ. The liver on a chip could cut tests on animals by providing an accurate artificial model of how the organ responds to new drugs. |
Chemistry World January 20, 2011 Erica Wise |
Protective shells for cells A highly permeable shell made for living cells could substantially extend their lifetime in bioengineering applications, including aiding bone repair, say US scientists. |
Chemistry World July 30, 2007 Lewis Brindley |
AFM Tip Feels Nano-Surfaces Scientists in the US have developed an artificial fingertip that boosts the resolution of atomic force microscopy, a technique that opens a window onto the nanoscale world. |
Chemistry World October 31, 2012 Ian Le Guillou |
A cell for a cell If you ever need to isolate a single bacterial cell, why not build it a prison cell? This is the approach that colleagues from Sandia National Laboratories, US, have taken. Using multi-photon lithography, they can construct four walls and a roof around a single cell in just over a minute. |
HHMI Bulletin Fall 2012 Ivan Amato |
The View from Here "Every major advance in imaging technology precipitates a new round of breakthroughs in cell biology," says structural biologist Grant Jensen, an HHMI investigator at the California Institute of Technology. |
Chemistry World August 22, 2011 Jon Cartwright |
Manmade molecular machine goes to work Manmade molecules can generate similar forces to natural molecular machines, and could help chemists to design artificial molecular machines for meaningful tasks. |
Chemistry World July 27, 2015 Tim Wogan |
Repellent nanocraters could shape tissue engineering Patterning surfaces with nanoscale craters can interfere with cells' ability to stick to surfaces, researchers in the US have shown. |
HHMI Bulletin Aug 2010 Richard Saltus |
Three-Dimensional Cell Cultures Thinking big but starting small, Sangeeta Bhatia is closing in on her ambitious goal: growing human livers in the lab from scratch. |
Chemistry World September 10, 2008 Simon Hadlington |
Failed anxiety drug could treat cancer Scientists believe they have solved the mystery of how a drug originally developed for treating anxiety can kill cancer cells. |
Chemistry World February 28, 2013 Andy Extance |
Chemical transport defines 'Goldilocks' cell size A US team has suggested molecular movement as an answer to the question of why cells are the size they are. A question that they say 'still awaits an answer from first principles'. |
Chemistry World February 28, 2007 Simon Hadlington |
Individual Atoms' Chemical ID Revealed Researchers have demonstrated for the first time that atomic force microscopy can be used to reveal the chemical identity of individual atoms on a surface at room temperature. |
Chemistry World January 16, 2014 |
The art of alternatives Recent years have seen great advances in alternatives to animal tests. Yet we still need to understand how and why compounds are toxic before we can make the giant leap to replacement. |
HHMI Bulletin Nov 2010 |
New live action microscopy lets scientists follow the first days of a zebrafish embryo's development The promise of live embryo imaging is unquestionable. Light-sheet microscopy will allow scientists for the first time to describe in detail the processes of development in complex vertebrates |
HHMI Bulletin May 2010 Robert Tjian |
Biomolecular Crowdsourcing A generation of web-savvy entrepreneurs has found a relatively cheap and effective approach to solving complex problems and soliciting ideas: toss out a challenge into a vibrant digital community and watch what happens. |
HHMI Bulletin Fall 2012 Elise Lamar |
Push and Pull Jennifer Zallen, an HHMI early career scientist at Memorial Sloan-Kettering Cancer Center, studies how embryonic tissues stretch along an anterior-posterior axis using the fruit fly Drosophila melanogaster as a model system. |
Chemistry World October 31, 2007 Lewis Brindley |
Filming the Nanoworld Scientists in the US have upgraded the circuitry on a popular microscopy technique to boost the speed of imaging by about 100 times |
HHMI Bulletin May 2010 Ivan Arnato |
Light Moves Light is becoming the tool of choice for researchers who want to precisely manipulate neurons and other cells. |
Scientific American June 2008 Melinda Wenner |
How Cells Make Use of Random Biochemical Reactions New studies reveal how cells exploit biochemical randomness. |
Bio-IT World August 2005 Maureen McDonough |
U.K. Framework Offers Stem Cells a Future The United Kingdom has managed to cut through the noise surrounding stem cell research, creating a regulatory framework that fosters an environment of international collaboration and excellent R&D programs. And they try to do it all in an ethical way. |
HHMI Bulletin May 2010 Sarah C.P. Williams |
Lab-Grown Liver New cell culture system solves problem of growing liver cells. |