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Bio-IT World May 19, 2004 |
Special Delivery TAT tagging has aroused keen interest in biotech. |
Chemistry World August 2, 2011 Phillip Broadwith |
Protein synthesis hijacked to turn out cyclic peptides Japanese researchers have developed a way of reprogramming the genetic code and using bacteria to make and screen huge libraries of cyclic peptides using unnatural amino acids. |
Chemistry World November 12, 2009 Hayley Birch |
New drug design looks top Notch against cancer A new type of drug that can block the switching on of certain genes in cancer cells has shown promise in mice. |
Chemistry World December 12, 2013 Jeanne Therese Andres |
Kiss-and-run drug delivery Carriers that release hydrophobic substances at cell membranes but do not enter the cells themselves could be the foundation for a new way to deliver drugs into cells, according to a team of scientists in Germany. |
Chemistry World June 9, 2008 Simon Hadlington |
Artificial virus silences genes Scientists in Korea have created an artificial virus that can target the nucleus of cancer cells and knock out specific genes. |
Chemistry World July 28, 2009 Michael Gross |
DNA to direct and switch off chemo Researchers in the US have developed a new approach to cancer chemotherapy using short DNA strands to help target delivery of the drug directly to cancer cells, and 'call it off' should problems arise. |
Chemistry World May 6, 2008 James Mitchell Crow |
Building Peptides From the Wrong End UK chemists have cracked a long-standing problem in peptide synthesis that has prevented amino acid chains being grown from both ends. The insight could open up efficient ways to make peptide-based drugs. |
Chemistry World June 28, 2009 Jon Cartwright |
Antimicrobial nanoparticles may help fight brain infections Antimicrobial nanoparticles that can cross the, almost impermeable, blood-brain barrier have been created by Asian researchers. |
Chemistry World March 19, 2014 Emma Stoye |
Molecular drill bits attack tuberculosis Peptides that punch through bacterial cell walls while leaving human cells unharmed could open up new ways to tackle antibiotic resistance, say researchers in the US. |
Chemistry World August 19, 2009 Phillip Broadwith |
Antioxidants could promote cancer Some tumor cells can actually use antioxidants to protect themselves from natural cellular defense mechanisms, enabling them to survive and proliferate. |
Chemistry World February 7, 2007 Bea Perks |
Protein's Non-Natural Alternative Beta peptides are of interest because of what they can tell researchers about protein folding in general. Now, chemical biologists have built what they say is a 'remarkably protein like' structure from beta peptides. |
HHMI Bulletin February 2011 Sarah C.P. Williams |
Releasing the Brakes on Cell Fate Converting one cell type directly into another is a kind of modern-day alchemy, an ultimate goal in biological research. But unlike turning base metals into gold, changing a cell's identity is feasible, new research shows. |
Chemistry World October 9, 2006 Michael Gross |
Miniature Microbicides Researchers have created miniature antimicrobial peptides that contain only four (as opposed to the usual 12-50) amino acid residues combined with a fatty acid. |
Chemistry World June 16, 2014 James Urquhart |
Handshake assembles new emulsions All it takes to make new stable emulsions with tuneable and novel properties is to give a simple mixture of water, solvent and peptide derivatives a quick shake by hand. |
Technology Research News March 26, 2003 |
Plastic coating makes chips biofriendly Electronics usually don't mix well with biological material. Sandia National Laboratories researchers have overcome the incompatibility with a microscopic laser designed to quickly measure and identify microorganisms and cell types without inhibiting biological processes. |
Chemistry World February 28, 2013 Andy Extance |
Chemical transport defines 'Goldilocks' cell size A US team has suggested molecular movement as an answer to the question of why cells are the size they are. A question that they say 'still awaits an answer from first principles'. |
Scientific American June 2008 Melinda Wenner |
How Cells Make Use of Random Biochemical Reactions New studies reveal how cells exploit biochemical randomness. |
Chemistry World February 21, 2014 Phillip Broadwith |
Refined gels for cultured cells UK start-up Biogelx is developing self-assembled peptide hydrogels that can provide support to growing cells, but also present well-defined surface chemistry to help cell biologists address biological problems. |
Chemistry World July 21, 2011 Elinor Richards |
Cell Control to Change Cell Function US scientists can now control the reactions occurring inside cells. |
Chemistry World August 10, 2015 Kira Welter |
Peptide glue may have held first protocell components together Electrostatic interactions induced by short, positively charged, hydrophobic peptides are all it takes to attach RNA to vesicle membranes. |
Chemistry World October 12, 2015 Andy Extance |
'Chemical search engine' backs alternative route to life A key class of biological molecules neglected in the search for life's chemical origins could have appeared spontaneously before organisms, UK scientists say. |
HHMI Bulletin Spring 2013 Sarah C.P. Williams |
Sounding the Alarm Details on how cells detect and respond to foreign DNA may provide clues to autoimmune diseases. |
Chemistry World August 20, 2008 |
Spying on Self-Assembly Proteins attaching to gold nanoparticles don't mill around randomly, but organise into clusters, according to UK scientists who say they have for the first time spied in detail peptides assembling on a surface. |
Chemistry World February 21, 2013 David Bradley |
Copycat flags help aliens avoid mouse immune system Synthetic peptide flags added to therapeutic and diagnostic agents can trick the immune system into ignoring them, according to US researchers. |
IEEE Spectrum August 2006 Schoenbach et al. |
Zap Extreme voltage could be a surprisingly delicate tool in the fight against cancer. The list of effects that scientists have achieved using nanoseconds-long pulses is growing rapidly, though their actual use as a medical treatment is still years away. |
Chemistry World September 7, 2014 Michael Gross |
Bringing chemical synthesis to the masses The promise of a novel approach to building chemical libraries, which only requires simple building blocks in water, without any additional reagents or sample preparation, is inspired by nature. |
HHMI Bulletin Aug 2011 Richard Saltus |
T-Cell Booster Kits A bioengineer remodels cell surfaces to prod the immune system. |
Chemistry World July 13, 2009 Lewis Brindley |
Getting a look at water wires Indian chemists have trapped tiny strands of water inside peptide nanotubes - allowing the researchers to take a direct look at how small amounts of water behave in a confined environment. |
HHMI Bulletin Aug 2010 |
Joaquin Espinosa's fresh look at p53 Even though it was discovered more than 25 years ago, and many more tumor suppressor genes have been found since, p53 remains the big one. It's mutated in about 50 percent of tumors. |
HHMI Bulletin Aug 2010 Richard Saltus |
Three-Dimensional Cell Cultures Thinking big but starting small, Sangeeta Bhatia is closing in on her ambitious goal: growing human livers in the lab from scratch. |
Chemistry World June 11, 2009 James Urquhart |
Enzyme-free assembly of DNA-like molecules US scientists have developed a simple peptide nucleic acid system that self-assembles and adapts to new instructions without enzymes. |
Chemistry World June 4, 2008 Lewis Brindley |
Peptide printer goes into overdrive Synthesizing arrays of short peptides could soon be as easy as printing them out - thanks to the development of a modified laser printer that uses amino acids instead of colored ink. |
Reactive Reports Issue 58 |
Anthrax Detector Researchers have developed a detector for anthrax spores based on a monoclonal antibody that recognizes a specific sugar on the bacterium. It might be possible to use this discovery to develop a passive immunization method. |
Chemistry World March 16, 2014 Simon Hadlington |
Short peptides self-assemble into a catalyst Researchers in the US have created catalysts from peptide chains that are only seven amino acids long. |
Chemistry World January 14, 2008 Michael Gross |
Ice-Cream Without the Crunch A mixture of molecules obtained from gelatin could help to make food last longer in the freezer and make ice-cream creamier. |
Reactive Reports October 2006 David Bradley |
Let it Bleed. Not! An international research team has shown that a biocompatible liquid can stop bleeding within seconds. The discovery could cut to the heart of many problems facing hospital emergency rooms and operating theaters. |
Chemistry World April 12, 2012 Alisa Becker |
Nanoscale engineering of wound beds A collagen-binding peptide with applications in wound healing has been developed by scientists in the US. |
Chemistry World April 11, 2008 Lewis Brindley |
Super Cells Made with 'Inorganic Armor' Chemists in China have coated living cells with egg-like shells, granting them a wide range of new properties. |
Chemistry World April 18, 2011 Kate McAlpine |
Shaping crystals with bio-tools Researchers in the US have developed a new approach for controlling crystal growth, borrowing tools from biology. |
Chemistry World August 15, 2007 John Bonner |
Chemists Claim Biological Alchemy South Korean chemists say they have turned muscle cells from the sole of a human foot into something akin to stem cells, using a simple molecule called neurodazine. |
Technology Research News August 25, 2004 |
Photosynthesis Drives Solar Cell Researchers have mixed biology and electronics in solar cells that use photosynthetic spinach leaf molecules or photosynthetic bacteria to convert light to electricity. |
Chemistry World July 31, 2012 Fiona McKenzie |
Sorting the good from the bad US scientists have found a way to separate cancerous cells from healthy cells by taking advantage of their adhesion properties. Separating cancer cells for analysis is a critical step for determining the recommended course of treatment for patients. |
Scientific American January 2009 Charles Q. Choi |
Do White Blood Cells Make Cancer Deadly? The ability to spread underlies the killing power of cancer. The process occurs, John Pawelek thinks, when tumor cells fuse with white blood cells -- an idea that, if right, could yield new therapies |
Chemistry World March 4, 2011 Russell Johnson |
Tracking the early stages of Alzheimer's disease UK researchers can track the early steps of formation of peptide clumps linked to Alzheimer's disease using the peptide's fluorescent ability. This could help design effective therapies for the disease at an early stage. |
AskMen.com Shannon Clark |
Lactoferrin Peptide Protein-intake is critical if you hope to make any gains from time spent at the gym. One type of peptide -- which is what forms a protein -- that is especially beneficial for men is lactoferrin. |
Chemistry World October 18, 2006 Michael Gross |
Death Sentences for Microbes Researchers have used methods borrowed from linguistics in the hunt for new antimicrobial agents. |
Chemistry World October 1, 2014 William Bergius |
Nitrogen dioxide and ozone: a sinister synergy Air pollution is detrimental to our health, but now scientists in Australia have revealed new mechanistic insight into how particular pollutants interact with the human respiratory tract. |
Chemistry World October 31, 2012 Ian Le Guillou |
A cell for a cell If you ever need to isolate a single bacterial cell, why not build it a prison cell? This is the approach that colleagues from Sandia National Laboratories, US, have taken. Using multi-photon lithography, they can construct four walls and a roof around a single cell in just over a minute. |
The Motley Fool November 28, 2007 Brian Orelli |
Stem Your Expectations of Stem-Cell Discoveries Making "stem" cells out of skin cells isn't all it's cracked up to be. The recent discovery has a long way to go before it can catch up to the research currently being done with stem cells. |
Technology Research News May 4, 2005 Eric Smalley |
Chip Gauges Cell Reactions Researchers have devised a way to test within minutes the reactions of cells to all types of stimuli. The researchers' system is very sensitive, relatively inexpensive, uses little power, and is portable. |