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Chemistry World March 16, 2014 Simon Hadlington |
Short peptides self-assemble into a catalyst Researchers in the US have created catalysts from peptide chains that are only seven amino acids long. |
Chemistry World November 2006 Philip Ball |
Opinion: The Crucible Here are some of the latest instalments in the ongoing story of how protein misfolding causes neurodegenerative diseases -- a story that is not solely about developing clinical treatments or preventative medicines, but which goes to the heart of proteins' role as the stuff of life. |
Chemistry World June 17, 2012 Jon Evans |
Anti-social amino acids gang up Previously thought to be purely the preserve of proteins and peptides, scientists have discovered that the amino acid phenylalanine can form the toxic amyloid fibrils that are a hallmark of diseases such as Alzheimer's and Parkinson's. |
Chemistry World December 10, 2009 Phillip Broadwith |
Solving fibril formation "It really is a case of the ideas of mathematics and physics helping us to understand chemistry and biology," says Chris Dobson of the University of Cambridge. |
Chemistry World April 2009 Philip Ball |
Column: The crucible Unwinding protein fibrils could give a glimpse of how peptides survived on early Earth |
Chemistry World February 3, 2011 Hayley Birch |
Nanoparticle studies guide coating design A new study provides guidance for designing nanoparticle coatings based on the particles' size and the environment they are to be used in. The research could help scientists create more effective nanoparticle drug carriers. |
Chemistry World November 15, 2010 Manisha Lalloo |
pH prompts protein structure US researchers studying the naturally-occurring amyloid protein Pmel17 have discovered that pH plays an important role in its structure, helping the body control its aggregation. |
Chemistry World June 14, 2009 Hayley Birch |
New technique probes Alzheimer's aggregates US and UK researchers have used a new technique to identify what they think could be the primary toxic species in the development of Alzheimer's disease |
Chemistry World March 4, 2011 Russell Johnson |
Tracking the early stages of Alzheimer's disease UK researchers can track the early steps of formation of peptide clumps linked to Alzheimer's disease using the peptide's fluorescent ability. This could help design effective therapies for the disease at an early stage. |
Chemistry World September 23, 2008 Simon Hadlington |
Nanoparticles Hide Behind Protein Cloak Polymer nanoparticles suspended in human blood become cloaked in plasma proteins, new research has shown. |
HHMI Bulletin Fall 2012 Halleh B. Balch |
Like a Chinese Finger Trap In neurodegenerative diseases like Alzheimer's, the needle-like fibers that accumulate in the brain are not the real damage-doers. The culprits are intermediate protein structures, called small amyloid oligomers, made of a few proteins that misfold and aggregate. |
Chemistry World September 21, 2006 Michael Gross |
Alzheimer's Alphabet Alzheimer's researchers are now closer to understanding the natural function of one of the two enzymes that cut A out of APP, and have recreated the process by which fibril formation begins in vivo. |
Chemistry World June 4, 2010 Manisha Lalloo |
Antibacterial nanoparticles from bacteria Scientists have found that silver nanoparticles made using bacteria have better antibacterial properties than their chemically synthesised counterparts. |
Chemistry World April 30, 2007 Victoria Gill |
Amyloid Protein Seen to Zip Together Amyloid proteins' long, complicated structure makes them tricky to study, but U.S. researchers have found that they share a common feature that could provide a drug target for an array of incurable conditions. |
Chemistry World May 1, 2012 David Bradley |
A colorful way to size up nanoparticles Researchers in China have now developed a straightforward light-scattering technique to estimate the size of gold nanoparticles in the 35 to 110nm range. |
Chemistry World May 7, 2009 Phillip Broadwith |
Polymers release insulin in response to glucose trigger Chinese researchers have developed polymer nanoparticles that can release insulin in response to changes in glucose concentration, creating a potential treatment for diabetes. |
Chemistry World August 24, 2009 Phillip Broadwith |
'Chemical nose' sensor sniffs blood protein profile US scientists have developed a sensor system for profiling the protein content of human blood serum without needing individual receptors for each separate protein. |
Reactive Reports September 2005 David Bradley |
Nano Surprise A surprising mechanism by which polymers form nanocomposite particles could provide researchers with a new tool for controlling the growth of such materials. |
Chemistry World October 18, 2007 Simon Hadlington |
Nanoparticle Reveals Sulfur's Midas Touch Researchers in the US have taken a snapshot of the inside of a gold nanoparticle, shedding crucial new light on one of chemistry's longest-standing questions: how does sulfur bind to gold? |
Chemistry World June 5, 2011 James Mitchell Crow |
Nanoparticles scrub up a treat in hot water bath Upping the catalytic activity of gold nanoparticles can be as simple as a good wash in hot water, UK chemists have shown. |
Chemistry World August 20, 2008 |
Spying on Self-Assembly Proteins attaching to gold nanoparticles don't mill around randomly, but organise into clusters, according to UK scientists who say they have for the first time spied in detail peptides assembling on a surface. |
Chemistry World March 6, 2006 Jon Evans |
Nanoprobes Light up Cellular Demolition Researchers have developed a method for detecting and imaging programmed cell death (apoptosis). The method, involving polymer nanoparticles, could be used to diagnose apoptosis-related diseases and inform drug development. |
Chemistry World April 1, 2011 Hayley Birch |
Nanoparticles help reveal hidden fingerprints A technique using gold nanoparticles in combination with antibodies has shown promising results for enhancing fingerprints that are over a week old. |
Chemistry World October 2, 2012 Fiona McKenzie |
Protein sorting within cells US scientists have used magnetic nanoparticles with specific ligands to latch on to and visualize specific proteins in living cells. |
Chemistry World November 30, 2015 Emma Stoye |
20 carat gold foam lighter than a feather The 20 carat gold 'foam' is a thousand times lighter than its solid counterpart, and the lightest gold nugget ever to be made. |
Chemistry World July 17, 2012 Harriet Brewerton |
Pinning down cancer US scientists have synthesized pin-shaped nanoparticles with magnetic and optical properties. The nanoparticles could be used for magnetic resonance imaging, early detection and photothermal therapy of cancer and other diseases. |
Chemistry World October 19, 2009 Lewis Brindley |
Nanoparticles brought to order US researchers have developed a process that could bring the unusual properties of nanoparticles to a larger scale, by using small molecules to evenly space nanoparticles in a polymer composite. |
Chemistry World August 2, 2006 Bea Perks |
Quantum Leap for Virus Trackers Glowing quantum dots are helping researchers study how viruses infect cells, and although the fluorescent nanoparticles have only been used on plant viruses so far, the technique could prove to be invaluable for drug development. |
Chemistry World February 3, 2006 Simon Hadlington |
High Throughput Screening for Kinase Inhibitors Researchers have developed a system for assessing the activity of a crucial class of enzymes involved in cellular signalling pathways. |
Chemistry World December 3, 2010 Emma Shiells |
No stone left unturned in oil hunt Polymer coated nanoparticles could be used to detect unrecovered oil in mature oil fields, say US scientists. |
Chemistry World July 21, 2015 Tim Wogan |
Nanoparticle cats drawn at the flick of a switch A new way of using light to reversibly assemble nanoparticles has been developed by scientists in Israel. |
Chemistry World February 23, 2011 Simon Hadlington |
Polymer coat helps nanoparticles penetrate mucus US researchers have shown how biodegradable, medically safe polymer coatings can help nanoparticles penetrate the mucus lining that protects human tissues to deliver drugs efficiently. |
Chemistry World April 11, 2006 Jon Evans |
Nanotechnology Tackles Chemotherapy Chemists and medical researchers have developed nanoparticles that target chemotherapy drugs directly at tumours. The researchers claim that the same technique could be used to develop nanoparticle-based treatments for a wide range of other diseases. |
Chemistry World July 29, 2014 Vijay Shankar |
Nanoparticle protects protein drug cargo A team of researchers at Brigham and Women's Hospital, Boston, US has developed novel nanoparticles that could deliver protein drugs to where they are needed unscathed. |
Chemistry World September 10, 2013 Emily Skinner |
Shape memory polymer hosts functional nanoparticles Scientists in China have developed a polymer scaffold for functional nanoparticles that can be folded and mangled but will reform into its original shape if it is placed in water. |
Chemistry World November 20, 2013 Rebecca Brodie |
Therapeutic screening for Alzheimer's disease Scientists in Canada and the US hope a system they have developed for monitoring amyloid- aggregation on a chip could be used to find new treatments for Alzheimer's disease. |
Chemistry World January 30, 2008 Jonathan Edwards |
DNA Helps Nanoparticles Crystallize Two papers in Nature have each shown a simple way to build designer crystals from nanoparticles, using DNA as 'glue'. Both methods show promise as a cheap way of mass-producing complex materials like photonic crystals. |
Chemistry World September 2, 2007 Lewis Brindley |
Nanoparticles Paint a Finer Picture Swiss scientists have developed a process that can print detailed images using nanoparticles as 'ink', while maintaining their catalytic and optical properties. |
Chemistry World October 7, 2011 Sarah Farley |
Detecting diseases with DNA sensors DNA sensors detect pathogenic and genetic diseases by binding to target DNA strands that are related to the disease and giving a signal that shows how much of the DNA is present. |
Chemistry World November 6, 2007 Lewis Brindley |
Soybeans Strike Nanogold A simple mix of soybeans, water and gold salts may hold the secret to producing gold nanoparticles without harming the environment, according to one team of US researchers. |
Chemistry World August 19, 2009 Hayley Birch |
Gold nanoparticles detect cancer Chinese scientists have used gold nanoparticles as ultrasensitive fluorescent probes to detect cancer biomarkers in human blood. |
Chemistry World August 21, 2014 David Bradley |
A new gold standard for nano The latest work confirms gold clusters can have super atomic and molecular characteristics. |
Chemistry World January 5, 2011 Hayley Birch |
Nanoparticles build up New research suggests that nanomaterials that are released into the environment could accumulate in food chains. |
Chemistry World July 20, 2012 Michael Parkin |
New supramolecular Alzheimer's drugs Supramolecular chemistry could provide a new avenue in the treatment of Alzheimer's disease, say scientists in China. |
Chemistry World May 8, 2015 Michaela Muehlberg |
Polymers curl up and take control Scientists in Germany have successfully collapsed single polymer chains into dense nanoparticles, to make single-chain nanoparticles, by adding palladium. |
Chemistry World November 25, 2011 Jon Evans |
Cancer diagnosis goes for gold Gold nanoparticles could help diagnose a wide range of different cancers by detecting telomerase activity within cells, say Chinese chemists. |
Chemistry World May 31, 2006 Jon Evans |
Carbon Joins the Dots Carbon could soon replace cadmium as the material of choice for quantum dots, following the development of fluorescent carbon nanoparticles by scientists. |
Chemistry World February 18, 2009 Nina Notman |
Single Nanocatalyst Behaviour Revealed Before you can design the perfect nanoparticle catalyst, you first need to understand the fundamental science that governs their reactivity. U.S. Scientists have said they have done just that. |
Chemistry World October 17, 2013 Jessica Brand |
Enhancing photopigment formation to boost biofuel production Scientists in Australia have developed a nanoparticle light filter system that only lets through wavelengths favorable for microalgae growth. The system could make producing algal biofuels more efficient. |
Chemistry World July 30, 2008 Sarah Houlton |
A metal trap to stop Alzheimer's Trapping metals could prove a key to curing Alzheimer's disease, according to the promising results of early clinical trials on a compound called PBT2. |