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Chemistry World June 14, 2009 Hayley Birch |
New technique probes Alzheimer's aggregates US and UK researchers have used a new technique to identify what they think could be the primary toxic species in the development of Alzheimer's disease |
Chemistry World April 2009 Philip Ball |
Column: The crucible Unwinding protein fibrils could give a glimpse of how peptides survived on early Earth |
Chemistry World September 12, 2014 Hayley Simon |
Coated nanoparticles show Alzheimer's promise Nanoparticles coated in an amino acid polymer have been found to prevent the formation of amyloid fibrils -- incorrectly folded protein fibers associated with the development of neurodegenerative diseases. |
Chemistry World March 4, 2011 Russell Johnson |
Tracking the early stages of Alzheimer's disease UK researchers can track the early steps of formation of peptide clumps linked to Alzheimer's disease using the peptide's fluorescent ability. This could help design effective therapies for the disease at an early stage. |
Chemistry World September 21, 2006 Michael Gross |
Alzheimer's Alphabet Alzheimer's researchers are now closer to understanding the natural function of one of the two enzymes that cut A out of APP, and have recreated the process by which fibril formation begins in vivo. |
HHMI Bulletin Fall 2012 Halleh B. Balch |
Like a Chinese Finger Trap In neurodegenerative diseases like Alzheimer's, the needle-like fibers that accumulate in the brain are not the real damage-doers. The culprits are intermediate protein structures, called small amyloid oligomers, made of a few proteins that misfold and aggregate. |
Chemistry World November 2006 Philip Ball |
Opinion: The Crucible Here are some of the latest instalments in the ongoing story of how protein misfolding causes neurodegenerative diseases -- a story that is not solely about developing clinical treatments or preventative medicines, but which goes to the heart of proteins' role as the stuff of life. |
Chemistry World April 30, 2007 Victoria Gill |
Amyloid Protein Seen to Zip Together Amyloid proteins' long, complicated structure makes them tricky to study, but U.S. researchers have found that they share a common feature that could provide a drug target for an array of incurable conditions. |
Chemistry World May 12, 2010 Phillip Broadwith |
Tying up spider silk's loose ends The way spider silk proteins can be stored as a fluid but spun instantly into fibres is all down to their end parts, European scientists have discovered. |
Chemistry World March 16, 2014 Simon Hadlington |
Short peptides self-assemble into a catalyst Researchers in the US have created catalysts from peptide chains that are only seven amino acids long. |
Science News June 30, 2007 Janet Raloff |
Infectious Foie Gras? Foie gras contains misfolded proteins that, when given to mice, trigger disease. |
Chemistry World February 24, 2012 Simon Hadlington |
Botox 'bodyguard' gives protein protection Researchers have discovered how one of the most potent toxins known to man can survive in the human stomach and digestive tract. |
Chemistry World July 20, 2012 Michael Parkin |
New supramolecular Alzheimer's drugs Supramolecular chemistry could provide a new avenue in the treatment of Alzheimer's disease, say scientists in China. |
Chemistry World July 22, 2009 Phil Taylor |
New drug turns Alzheimer's theory on its head Researchers have been left puzzled by data showing that the antihistamine dimebolin, a drug with promising activity in improving Alzheimer's symptoms, actually seems to increase levels of the toxic protein beta amyloid. |
The Motley Fool January 12, 2005 Charly Travers |
Alzheimer's Drug on the Horizon? Myriad Genetics' innovative technology creates an investment opportunity. |
Chemistry World July 30, 2008 Sarah Houlton |
A metal trap to stop Alzheimer's Trapping metals could prove a key to curing Alzheimer's disease, according to the promising results of early clinical trials on a compound called PBT2. |
Chemistry World December 10, 2009 Phillip Broadwith |
Solving fibril formation "It really is a case of the ideas of mathematics and physics helping us to understand chemistry and biology," says Chris Dobson of the University of Cambridge. |
Chemistry World October 14, 2009 Phil Taylor |
Tracing amyloid in Alzheimer's A diagnostic compound that allows researchers to look into the brains of Alzheimer's patients will be used for the first time to gauge the effects of an experimental therapy for the disease. |
Chemistry World January 26, 2011 Jon Cartwright |
Luminescence gives 2D pH images Researchers in Germany have devised a safe method to image the pH of tissue in the human body. The method, which involves measuring the luminescence of injected dyes, could help physicians monitor wound healing and tumour growth. |
Chemistry World November 20, 2013 Rebecca Brodie |
Therapeutic screening for Alzheimer's disease Scientists in Canada and the US hope a system they have developed for monitoring amyloid- aggregation on a chip could be used to find new treatments for Alzheimer's disease. |
Chemistry World June 17, 2012 Jon Evans |
Anti-social amino acids gang up Previously thought to be purely the preserve of proteins and peptides, scientists have discovered that the amino acid phenylalanine can form the toxic amyloid fibrils that are a hallmark of diseases such as Alzheimer's and Parkinson's. |
Prepared Foods February 2008 Sharon Book |
Article: Protein Ingredients for Health and Texture A variety of soy, dairy and egg proteins are available for the food formulator to obtain the desired texture in a food or beverage. |
Chemistry World March 23, 2010 Sarah Houlton |
Microbes implicated in Alzheimer's Microbes such as Candida albicans may be triggering the immune system to release beta amyloid |
Chemistry World December 20, 2011 Simon Hadlington |
pH adjustable protein micro-lenses Scientists in China have used a common protein to create tiny optical lenses, a few tens of micrometres in diameter, whose focus can be adjusted simply by changing the pH of the surrounding medium. |
Chemistry World July 9, 2013 Daniel Johnson |
Stealthy nanoparticles gather to take on tumors A team of Chinese scientists have created nanoparticles that respond to changes in pH, clumping together in acidic conditions. |
The Motley Fool January 19, 2011 Brian Orelli |
High Stakes at Tomorrow's FDA Panel Meeting It's more than just Eli Lilly on the line. |
The Motley Fool August 17, 2010 Brian Orelli |
Forget About This Drug Saving the Company Lilly's Alzheimer's drug fails hard. |
BusinessWeek January 8, 2007 Catherine Arnst |
Decoding Alzheimer's After a century, promising treatments at last - and whispers of a cure. |
Chemistry World July 3, 2014 Maria Burke |
Renewed focus on dementia checked by drug challenges The risks and barriers for companies working in dementia are huge, but so too, potentially, are the rewards, says Simon Ridley, head of research at Alzheimer's Research UK. |
Prepared Foods July 1, 2005 Marcia A. Wade |
The Importance of Being Protein Milk, egg, wheat and soy proteins can pass for other ingredients and create fluffy, flowing and fabulous textures. |
Pharmaceutical Executive December 1, 2010 Walter Armstrong |
Alzheimer's: A Disease at a Crossroads The need for new drugs intensifies as more and more Baby Boomers live into advanced old age. The global market is estimated to be worth $20 billion by the end of the decade. |