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Chemistry World April 2009 Philip Ball	Column: The crucible Unwinding protein fibrils could give a glimpse of how peptides survived on early Earth
Chemistry World November 2006 Philip Ball	Opinion: The Crucible Here are some of the latest instalments in the ongoing story of how protein misfolding causes neurodegenerative diseases -- a story that is not solely about developing clinical treatments or preventative medicines, but which goes to the heart of proteins' role as the stuff of life.
Chemistry World June 17, 2012 Jon Evans	Anti-social amino acids gang up Previously thought to be purely the preserve of proteins and peptides, scientists have discovered that the amino acid phenylalanine can form the toxic amyloid fibrils that are a hallmark of diseases such as Alzheimer's and Parkinson's.
Chemistry World October 12, 2015 Andy Extance	'Chemical search engine' backs alternative route to life A key class of biological molecules neglected in the search for life's chemical origins could have appeared spontaneously before organisms, UK scientists say.
Chemistry World September 12, 2014 Hayley Simon	Coated nanoparticles show Alzheimer's promise Nanoparticles coated in an amino acid polymer have been found to prevent the formation of amyloid fibrils -- incorrectly folded protein fibers associated with the development of neurodegenerative diseases.
Chemistry World March 4, 2011 Russell Johnson	Tracking the early stages of Alzheimer's disease UK researchers can track the early steps of formation of peptide clumps linked to Alzheimer's disease using the peptide's fluorescent ability. This could help design effective therapies for the disease at an early stage.
HHMI Bulletin Fall 2012 Halleh B. Balch	Like a Chinese Finger Trap In neurodegenerative diseases like Alzheimer's, the needle-like fibers that accumulate in the brain are not the real damage-doers. The culprits are intermediate protein structures, called small amyloid oligomers, made of a few proteins that misfold and aggregate.
Chemistry World October 27, 2014 Tim Wogan	Folding rules used to build unnatural proteins Scientists in the UK and US have designed and synthesized unnatural protein structures, using theoretical calculations to explore the factors affecting protein folding and stability.
Chemistry World February 7, 2007 Bea Perks	Protein's Non-Natural Alternative Beta peptides are of interest because of what they can tell researchers about protein folding in general. Now, chemical biologists have built what they say is a 'remarkably protein like' structure from beta peptides.
Chemistry World May 6, 2008 James Mitchell Crow	Building Peptides From the Wrong End UK chemists have cracked a long-standing problem in peptide synthesis that has prevented amino acid chains being grown from both ends. The insight could open up efficient ways to make peptide-based drugs.
Chemistry World August 28, 2011 Simon Hadlington	Synthetic self-assembling collagen for tissue engineering US researchers have succeeded in making the most realistic synthetic collagen to date.
Chemistry World June 14, 2009 Hayley Birch	New technique probes Alzheimer's aggregates US and UK researchers have used a new technique to identify what they think could be the primary toxic species in the development of Alzheimer's disease
Chemistry World July 20, 2012 Michael Parkin	New supramolecular Alzheimer's drugs Supramolecular chemistry could provide a new avenue in the treatment of Alzheimer's disease, say scientists in China.
Chemistry World October 9, 2006 Michael Gross	Miniature Microbicides Researchers have created miniature antimicrobial peptides that contain only four (as opposed to the usual 12-50) amino acid residues combined with a fatty acid.
Chemistry World August 2, 2011 Phillip Broadwith	Protein synthesis hijacked to turn out cyclic peptides Japanese researchers have developed a way of reprogramming the genetic code and using bacteria to make and screen huge libraries of cyclic peptides using unnatural amino acids.
Chemistry World November 15, 2010 Manisha Lalloo	pH prompts protein structure US researchers studying the naturally-occurring amyloid protein Pmel17 have discovered that pH plays an important role in its structure, helping the body control its aggregation.
Chemistry World September 21, 2006 Michael Gross	Alzheimer's Alphabet Alzheimer's researchers are now closer to understanding the natural function of one of the two enzymes that cut A out of APP, and have recreated the process by which fibril formation begins in vivo.
Chemistry World August 20, 2008	Spying on Self-Assembly Proteins attaching to gold nanoparticles don't mill around randomly, but organise into clusters, according to UK scientists who say they have for the first time spied in detail peptides assembling on a surface.
Chemistry World July 30, 2008 Sarah Houlton	A metal trap to stop Alzheimer's Trapping metals could prove a key to curing Alzheimer's disease, according to the promising results of early clinical trials on a compound called PBT2.
Chemistry World December 10, 2009 Phillip Broadwith	Solving fibril formation "It really is a case of the ideas of mathematics and physics helping us to understand chemistry and biology," says Chris Dobson of the University of Cambridge.
Chemistry World November 27, 2013 Jennifer Newton	A cytochrome from scratch Artificial proteins could be closer to participating in natural biochemical pathways after researchers show that bacteria will process amino acid sequences entirely unrelated to any natural protein to produce a fully functioning cytochrome.
Chemistry World July 26, 2007 Richard Van Noorden	Shortcut Protein Synthesis Ditches Amino Acids Chinese chemists have demonstrated a speedy way to make polypeptides by avoiding the costly tedium of linking together amino acids.
Chemistry World January 21, 2011 David Barden	Close encounter makes modifying proteins easy Chemists in the US have now developed a powerful strategy for selectively modifying the side-chains of proteins, which they hope will enable the creation of new tools to investigate protein interactions involved in human diseases.
Chemistry World June 4, 2008 Lewis Brindley	Peptide printer goes into overdrive Synthesizing arrays of short peptides could soon be as easy as printing them out - thanks to the development of a modified laser printer that uses amino acids instead of colored ink.
Bio-IT World June 12, 2002 Karen Hopkin	Computational Biologists Join the Fold CASP5 competitors compare the best algorithms for modeling the 3-D structure of proteins -- an exercise that could lead to new insights into the pathogenesis and treatment of disease.
Chemistry World April 30, 2007 Victoria Gill	Amyloid Protein Seen to Zip Together Amyloid proteins' long, complicated structure makes them tricky to study, but U.S. researchers have found that they share a common feature that could provide a drug target for an array of incurable conditions.
Chemistry World July 15, 2010 Simon Hadlington	Synthetic enzyme catalyses Diels-Alder reaction The reaction is key to many organic syntheses and suggests that artificial enzymes could soon become part of the synthetic chemist's toolkit.
Bio-IT World October 10, 2003 Jeffrey Skolnick	Protein Structure Prediction in Drug Discovery Indications are that structure prediction can assist in the automated assignment of proteins to known pathways.
Chemistry World December 21, 2006 Henry Nicholls	Silent SNPs Serve up a Structural Surprise The sequence of amino acids no longer dictates the structure and function of a protein according to a surprising new paper.
Chemistry World October 8, 2008 Sarah Houlton	Artificial protein chemistry licensed to industry UK researchers are licensing to industry their method of making artificial proteins by chemically modifying individual amino acid structures.
Chemistry World June 11, 2009 James Urquhart	Enzyme-free assembly of DNA-like molecules US scientists have developed a simple peptide nucleic acid system that self-assembles and adapts to new instructions without enzymes.
Chemistry World November 3, 2014 Debbie Houghton	Engineered metalloenzyme catalyses Friedel -- Crafts reaction Reprogramming the genetic code of bacteria to incorporate an unnatural amino acid has allowed scientists in the Netherlands to create a new metalloenzyme capable of catalyzing an enantioselective reaction.
AskMen.com Shannon Clark	Lactoferrin Peptide Protein-intake is critical if you hope to make any gains from time spent at the gym. One type of peptide -- which is what forms a protein -- that is especially beneficial for men is lactoferrin.
Chemistry World October 14, 2009 James Urquhart	New route to amino acids US scientists have found a new way of making a class of non-natural amino acids that are widely used as components of pharmaceuticals and chiral catalysts.
Chemistry World July 22, 2009 Phil Taylor	New drug turns Alzheimer's theory on its head Researchers have been left puzzled by data showing that the antihistamine dimebolin, a drug with promising activity in improving Alzheimer's symptoms, actually seems to increase levels of the toxic protein beta amyloid.
Chemistry World November 20, 2013 Rebecca Brodie	Therapeutic screening for Alzheimer's disease Scientists in Canada and the US hope a system they have developed for monitoring amyloid- aggregation on a chip could be used to find new treatments for Alzheimer's disease.
Prepared Foods June 1, 2005 Marcia A. Wade	Extended Shelflife: Bar None A partially hydrolyzed premium whey protein isolate designed to control water migration can extend the shelflife of nutrition bars -- up to a year, in some cases.
Chemistry World October 18, 2006 Michael Gross	Death Sentences for Microbes Researchers have used methods borrowed from linguistics in the hunt for new antimicrobial agents.
Chemistry World July 2, 2014 Tim Wogan	Miller's forgotten experiments point to primitive protein genesis Stanley Miller's experiments are still adding to our understanding of prebiotic Earth.
Chemistry World January 10, 2013 Laura Howes	Rotaxane mimics ribosome to spin out peptides The field of molecular machines has taken a new bio-inspired turn to assemble another molecule, in this case linking up individual amino acids into a peptide.
Chemistry World September 7, 2014 Michael Gross	Bringing chemical synthesis to the masses The promise of a novel approach to building chemical libraries, which only requires simple building blocks in water, without any additional reagents or sample preparation, is inspired by nature.
Prepared Foods February 2008 Sharon Book	Article: Protein Ingredients for Health and Texture A variety of soy, dairy and egg proteins are available for the food formulator to obtain the desired texture in a food or beverage.
HHMI Bulletin February 2011 Michele Solis	Right Before Your Eyes Coupling protein sequence to function, thousands of variants at a time.
Pharmaceutical Executive November 1, 2006	Thoughtleader: Making Things Stick Ambrx has created the "glue" that allows researchers to attach activity-enhancing molecules to amino acids where they couldn't before.
Chemistry World September 30, 2014 Kirsty Muirhead	Mirror peptides hitch a lift into the cell Scientists in the US have developed a method for successfully transporting chemotherapeutic d-peptides into the cell cytosol.
Chemistry World October 1, 2010 Hayley Birch	On-off catalyst mimics enzyme function US and Japanese researchers have created an enzyme-like catalyst whose activity can be switched on or off using small molecules.
Chemistry World June 16, 2014 James Urquhart	Handshake assembles new emulsions All it takes to make new stable emulsions with tuneable and novel properties is to give a simple mixture of water, solvent and peptide derivatives a quick shake by hand.
Chemistry World October 14, 2009 Phil Taylor	Tracing amyloid in Alzheimer's A diagnostic compound that allows researchers to look into the brains of Alzheimer's patients will be used for the first time to gauge the effects of an experimental therapy for the disease.
Chemistry World March 23, 2010 Sarah Houlton	Microbes implicated in Alzheimer's Microbes such as Candida albicans may be triggering the immune system to release beta amyloid
AskMen.com Bryan Tomek	Supplements Guide When it comes to supplements, understanding fact from fiction can be crucial to your health.