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IEEE Spectrum March 2011 Lucks & Arkin |
Synthetic Biology's Hunt for the Genetic Transistor How genetic circuits will unlock the true potential of bioengineering |
Chemistry World November 15, 2007 Tom Westgate |
Computing Goes Into Solution South Korean scientists have developed the first soluble molecular logic gates - one step along the way to designing molecular computers and biological lab-on-a-chip devices. |
Chemistry World November 25, 2013 Carla Pegoraro |
Steering cells towards biocomputers Bacterial toxins that undergo unique cell interactions have been used to perform logic functions by researchers in Germany. This innovation will help push the limits of synthetic biology. |
Chemistry World May 17, 2007 Richard Van Noorden |
Bacterial Navigation Reprogrammed U.S. scientists have forced bacteria to follow new chemical signals by tweaking the bugs' natural guidance system. |
Chemistry World July 18, 2014 Melissae Fellet |
Molecular computer calculates Ebola diagnosis A molecular computer could one day simplify analysis of biomedical assays like those used to diagnose Ebola, researchers say. |
Scientific American January 2006 Charles Q. Choi |
Un-Killing the Messenger Processing bodies do more than serve as RNA trash bins in cells. Research now suggests that these P-bodies are less like junkyards and more like office centers, where messages are amassed, silenced and reactivated. |
Technology Research News May 5, 2004 Kimberly Patch |
DNA Bot Targets Cancer Researchers from Israel have constructed a molecular-size computer that is programmed to find signs of cancer cells, and when they are present, dispense DNA molecules designed to eradicate those cells. |
Chemistry World April 20, 2009 James Urquhart |
New method reveals small molecule-RNA conjugates US scientists using novel chemical screening methods have discovered a new class of small molecules connected to RNA, suggesting that cellular RNA may be more chemically diverse than previously thought. |
Technology Research News August 27, 2003 Kimberly Patch |
DNA plays tic-tac-toe In addition to its natural role as the blueprint of life, DNA has been tapped to compute and to form nanoscale machines. A new type of DNA logic is aimed at marrying these artificial functions to make control circuits for nano machines. The first result is an unbeatable tic-tac-toe player. |
Chemistry World May 12, 2008 Simon Hadlington |
'Super-yeast' tackles unnatural proteins Researchers in the US have engineered yeast cells to produce large amounts of proteins containing unnatural amino acids (UAAs) - a feat that has previously only been possible with bacteria. |
Chemistry World May 18, 2011 James Urquhart |
Throwing light on molecular logic gates The multifunctional molecule, which can be reconfigured by light, could be used in data storage devices and biomedicine, including nanoparticle tracking and drug delivery. |
Chemistry World September 23, 2009 Simon Hadlington |
Direct route to RNA sequences Scientists in the US appear to have cracked a major problem in molecular biology: how to sequence single molecules of RNA directly. |
Chemistry World February 12, 2014 Manisha Lalloo |
Synthetic strategy targets 'undruggable' small RNAs Chemists in the US have found a way to predict small molecules that can target short pieces of RNA involved in some diseases, such as cancer. |
Chemistry World November 27, 2007 James Mitchell Crow |
A Flare for Gene Silencing US scientists have developed nanoparticle probes coated with DNA that release fluorescent 'flares' when they silence genes inside cells. |
Technology Research News August 22, 2005 |
DNA Technologies The versatile DNA molecule has proven to be a powerful technological building block. Researchers have developed ways of combining DNA molecules that allow them to carry out computations in test tubes and create two-dimensional patterns and three-dimensional structures at the nanoscale. |
Chemistry World October 25, 2010 |
Playing Games with Enzymes US researchers have shown that a solution of biological molecules can be taught to play any strategy of a simple board game against a human opponent and never lose. |
Chemistry World January 20, 2011 Hayley Birch |
Programmable RNA promising for bio-compatible therapies Programmable nanostructures based on ribonucleic acid could be used as vessels for shipping therapeutic molecules into cells, according to US scientists. |
Technology Research News March 24, 2004 Eric Smalley |
Molecular logic proposed Researchers from the French National Center for Scientific Research (CNRS) and University College London in England have devised a scheme for designing logic circuits within individual molecules. |
Chemistry World March 21, 2013 Phillip Broadwith |
AstraZeneca partners with Moderna for $240 million Moderna has developed a way to use messenger RNA (mRNA), the molecule cells use to turn DNA into proteins, to stimulate the production of specific proteins in cells where disease has diminished or eliminated their ability to do so. |
HHMI Bulletin Spring 2013 Sarah C.P. Williams |
Sounding the Alarm Details on how cells detect and respond to foreign DNA may provide clues to autoimmune diseases. |
Chemistry World July 23, 2012 Melissae Fellet |
RNA wrapper protects small molecules Step aside benzene rings, there's a new protecting group in town. Dutch researchers have used a strand of RNA to cover portions of a complex small molecule. They then chemically modified a portion of the molecule not covered by the RNA. |
HHMI Bulletin February 2012 Sarah C. P. Williams |
Force Factor In the context of cells, forces are required to move molecules. Quantifying these forces gives scientists a way to compare and contrast different molecular motors. |
Chemistry World May 13, 2009 Lewis Brindley |
Combination nanoparticles to fight cancer Korean chemists have assembled a multitalented nanoparticle that can hunt down, treat, and illuminate cancerous cells. |
Chemistry World June 9, 2008 Simon Hadlington |
Artificial virus silences genes Scientists in Korea have created an artificial virus that can target the nucleus of cancer cells and knock out specific genes. |
Reactive Reports October 2006 David Bradley |
Amilra Prasanna "AP" de Silva An interview with the Queen's University of Belfast chemistry professor on his fascinating research into logical molecules. |
Managed Care November 2003 Thomas Morrow |
Making Sense of Antisense and Interference Treatments that interfere with protein synthesis at the cellular level will soon be debated in medical policy committee meetings. |
Chemistry World May 12, 2011 Jon Cartwright |
'Chemical soldering' heralds single molecule electronics Scientists in Japan and Switzerland have demonstrated how to wire up single molecules with conductive nanowires. |
HHMI Bulletin Winter 2013 Sarah C.P. Williams |
Cellular Search Engine Craig Mello's lab has now uncovered the reason piRNA molecules are so ubiquitous and exist in so many forms in C. elegans: so they can pair with essentially any genetic sequence they encounter during their endless scanning. |
Chemistry World March 15, 2007 Henry Nicholls |
The Mother of All Enzymes Scientists have uncovered the three-dimensional structure of what might be biology's first enzyme. This sheds light on the chemistry at a key moment in the origin of life, they argue. |
CIO June 1, 2003 Bob Violino |
Powerful DNA Portable computer vendors like to boast about their small and lightweight devices. But their best efforts are nothing compared with programmable molecular computing machines composed of an enzyme and DNA molecules. |
Technology Research News December 3, 2003 Kimberly Patch |
DNA assembles nanotube transistor Scientists have caused a transistor to self-assemble from a test tube concoction of DNA, proteins, antibodies, carbon nanotubes and minuscule specks of silver and gold. The feat shows that it is possible to assemble the smallest of machines and electronic devices by harnessing DNA's properties. |
Chemistry World August 13, 2013 Uwe Pischel |
Molecular logic-based computation This book, by A. Prasanna de Silva, will serve the expert, as well as interested scientists from other specialties related to any aspect of molecular logic. |
Chemistry World July 17, 2012 Simon Perks |
Synthetic nanozymes silence hepatitis C Researchers at the University of Florida, US, have discovered that an artificial nanoparticle complex, known as a nanozyme, can help to treat viral infections by 'shutting off' their genetic material. |
Chemistry World February 1, 2008 Lewis Brindley |
Genetic Code Read Directly From RNA Scientists have directly read the genetic code from a single strand of RNA for the first time, using a combination of powerful microscopes and laser spectroscopy techniques. |
Chemistry World February 27, 2006 Michael Gross |
A DNA Switch for RNA Folding Researchers have equipped a large RNA domain with a DNA switch, which they say can fold or unfold the RNA molecule at will. |
Chemistry World March 10, 2008 Simon Hadlington |
Cell's Protein Factory Seen in Action Researchers have observed one of nature's most remarkable molecular machines in action. |
Chemistry World January 5, 2007 Richard Van Noorden |
Password Protection Goes Molecular Israeli scientists have invented the ultimate in small-scale security: a molecule that acts like an electronic keypad lock. |
Chemistry World September 19, 2007 Lewis Brindley |
Cell Destruction by Gel Implosion Scientists in Hong Kong have shown that creating a gel inside bacterial cells can stunt their growth. This research is a step towards developing novel treatments that would target rapidly-reproducing cells such antibiotic-resistant superbugs. |
Information Today February 13, 2012 |
Elsevier Launches TargetInsights for Early Drug Discovery This online decision support tool enables scientists to search, monitor, and stay up-to-date with the latest biological insights reported in the scientific literature. |
Chemistry World March 27, 2014 James Urquhart |
Synthetic yeast chromosome is fully functional The first complete and functional synthetic yeast chromosome has been created by a team of scientists based in the US. |
Technology Research News June 15, 2005 Kimberly Patch |
DNA Machine Links Molecules Researchers have fashioned a nanomechanical device from DNA that can be programmed to align a series of molecules and fuse them together. The technique could potentially be used to put together designer polymers, encrypt information, and carry out computations. |
Chemistry World August 22, 2008 Hayley Birch |
Drug uptake rule challenged A study by UK scientists apparently contradicts a 100-year-old rule thought to govern the rate at which molecules cross biological membranes. |
Technology Research News January 12, 2005 |
RNA Tiles Form Nanopatterns Researchers have developed a method of coaxing artificial RNA molecules to self-assemble into specific shapes, much like a jigsaw puzzle automatically assembling. The structures could eventually be used as templates for nanochips, nanocircuits and nanocrystals |
Technology Research News March 12, 2003 |
RNA forms nanomotor Researchers from Purdue University have constructed a tiny motor from DNA and RNA molecules. The device, fueled by ATP, which powers our own movements, could eventually power nanomachines. |
Chemistry World January 31, 2008 John Bonner |
RNAi Scores Victory Against Crohn's Disease in Mice Thousands of people suffering from the debilitating gut condition Crohn's disease could experience relief from their symptoms through a technique that blocks production of a key protein in the inflammation process. |
Chemistry World July 28, 2009 Michael Gross |
DNA to direct and switch off chemo Researchers in the US have developed a new approach to cancer chemotherapy using short DNA strands to help target delivery of the drug directly to cancer cells, and 'call it off' should problems arise. |
HHMI Bulletin Winter 2013 Megan Scudellari |
Tunneling Out A research team including HHMI investigator Melissa Moore at the University of Massachusetts Medical School has discovered an alternative passageway used by RNA -- protein complexes to exit the nucleus. |
Chemistry World January 25, 2010 Hayley Birch |
Stabilising RNAs enhances gene silencing in tumours South Korean scientists have found a way to stabilise therapeutic RNA molecules, using chemical modifications, so that they can be more smoothly trafficked into cells. |
Chemistry World October 4, 2006 Bea Perks |
Good Year for RNA Roger Kornberg, professor of structural biology at Stanford University, has been awarded the 2006 Nobel prize in chemistry for his work on the molecular basis of transcription. |
Bio-IT World December 15, 2004 David A. Bumcrot |
Identifying RNAi Drug Candidates Breakthroughs in understanding RNA's extensive role in essential cellular processes have opened up the potential for a whole new class of drugs based on RNAi. |