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Chemistry World
June 8, 2014
David Bradley
Carbon--carbon couplings go 3D Chemists have devised a new stereospecific coupling reaction for electron-rich aromatics using secondary and tertiary boronic esters that works under mild conditions. mark for My Articles similar articles
Chemistry World
September 10, 2014
Andy Extance
'Assembly line' sculpts carbon chains UK chemists have devised a precise process for building carbon chains a link at a time that packs in more side groups than biologically-derived molecules can. mark for My Articles similar articles
Chemistry World
January 27, 2010
Simon Hadlington
Fruity route to control asymmetric syntheses Chemists in the UK have discovered a quick, cheap and easy way to make a key sulfide reagent that can mediate the formation of chirally selective molecules needed for complex organic syntheses. mark for My Articles similar articles
Chemistry World
June 2010
Paul Docherty
Column: Totally Synthetic Although its chemistry is mature and varied, my use of silicon reagents in my synthetic forays has been limited to a somewhat clumsy use of hydroxyl protecting groups. mark for My Articles similar articles
Chemistry World
October 5, 2006
Mark Peplow
Boron Shows Its Negative Side A molecule that hosts a negatively-charged boron atom could prove to be an exciting addition to the chemist's toolbox, according to researchers who have isolated the anion as its lithium salt. mark for My Articles similar articles
Chemistry World
July 9, 2012
Phillip Broadwith
'Molecular cobra' turns C-H to C=C A reagent developed by US chemists can selectively introduce synthetically useful C=C double bonds into unactivated carbon chains, guided by an activating group attached to a nearby oxygen or nitrogen atom. mark for My Articles similar articles
Chemistry World
February 21, 2007
Tom Westgate
Complex Organic Molecules Teamed with Iodine Chemists have developed a method for constructing complex halogen-containing organic molecules from simple compounds in a single step. The discovery could pave the way for the synthesis of many potentially useful naturally occurring molecules. mark for My Articles similar articles
Chemistry World
October 4, 2007
Richard Van Noorden
Nanofibers Show Hydrogen Promise UK chemists have overcome the shortcomings of a promising hydrogen storage material by simply converting it into nanofibers. mark for My Articles similar articles
Chemistry World
July 3, 2015
Andy Extance
Copper catalysis overcomes double bond trouble Some carbon-carbon double bonds seem too unreactive for synthetic use -- but that's just how chemists in the US are now exploiting them. mark for My Articles similar articles
Chemistry World
November 6, 2009
Phillip Broadwith
Enzyme binds both sides of the mirror European chemists have discovered that both mirror-image forms of a particular compound can bind at the same time in the same site of an enzyme, a phenomenon that has never been seen before. mark for My Articles similar articles
Chemistry World
September 6, 2006
Michael Gross
Selective Shortcut Chemists have developed a simple catalyst that speeds up the synthesis of a chiral protected building block used in many complex syntheses. mark for My Articles similar articles
Chemistry World
December 17, 2009
Simon Hadlington
Single catalyst gives two products from racemic mixture Chemists in the US have demonstrated a remarkable reaction in which a single catalyst can transform a racemic mixture - molecules identical in every way except for their chirality - into two distinct enantiomerically pure products. mark for My Articles similar articles
Chemistry World
July 8, 2010
Phillip Broadwith
Flattening carbon UK researchers have managed to synthesise a molecule with an almost planar four-coordinate carbon atom bonded to two lithium atoms and bulky organic ligands. mark for My Articles similar articles
Chemistry World
July 2009
Paul Docherty
Column: Totally Synthetic When it comes to making large natural products, different researchers will often propose identical 'end-game' strategies to complete the target. mark for My Articles similar articles
Chemistry World
January 6, 2013
Simon Hadlington
Greener route to carboxylic acids Chemists in Israel have developed a new way to oxidize primary alcohols to carboxylic acids, using water as both the reaction solvent and the source of oxygen. mark for My Articles similar articles
Chemistry World
May 30, 2013
Andy Extance
Catalyst duo exerts powerful stereocontrol Chemists from the Swiss Federal Institute of Technology, ETH Zurich, have teamed chiral catalysts in pairs to selectively drive a reaction towards desired stereoisomeric products with high selectivity. mark for My Articles similar articles
Chemistry World
September 6, 2013
Melissae Fellet
Unravelling stereochemistry via mass spectrometry Researchers have used mass spectrometry to determine the stereochemistry of a prototypical chiral molecule, CHBrClF. mark for My Articles similar articles
Chemistry World
April 1, 2014
Karl Collins
Reduced to clear Reducing amides to primary alcohols may instinctively seem like a simple functional group transformation. But as undergraduate chemists soon find out, this unfortunately isn't the case. mark for My Articles similar articles
Chemistry World
June 1, 2006
Michael Gross
New Twists on Catalysis Chemists around the world have discovered several new twists to improve the performance of asymmetric catalysts in hydrogenation reactions. mark for My Articles similar articles
Chemistry World
January 19, 2007
Richard Van Noorden
Happy Families for Aluminium Chemists have discovered that aluminium - a notoriously anti-social element compared with its sister boron - may in fact form an unexpected family of hydride clusters. mark for My Articles similar articles
Chemistry World
June 13, 2008
Richard Van Noorden
Asymmetric ketone catalysis gets pharma-scale makeover An asymmetric catalysis reaction limited to laboratory syntheses has received a makeover that could see it used on a large scale by drug-makers. mark for My Articles similar articles
Chemistry World
February 13, 2014
Tim Wogan
Greener route to esters dodges toxic reactant The industrially important synthesis of esters could be set to become greener and safer as German chemists have found a way to use carbon dioxide in place of carbon monoxide for alkoxycarbonylation. mark for My Articles similar articles
Technology Research News
January 15, 2003
Eric Smalley
Metal stores more hydrogen One reason the world isn't running on hydrogen fuel is that it's hard to store. Researchers from the National University of Singapore have made an accidental discovery that brings the promise of clean hydrogen energy a big step forward. mark for My Articles similar articles
Chemistry World
March 2012
Column: In the pipeline Drug discovery requires experimentation, says Derek Lowe. But chemists can be reluctant to stray from the elements they know and love mark for My Articles similar articles
Chemistry World
May 2010
Paul Docherty
Column: Totally Synthetic In the case of englerin A, the synthetic strategies used by Dawei Ma's group at the Chinese Academy of Sciences, Shanghai, China, 1 and Antonio Echavarren's team at Rovira and Virgili University, Tarragona, Spain, 2 are extremely similar. mark for My Articles similar articles
Chemistry World
October 31, 2014
Andy Extance
Acid choice flips enantioselectivity Organic chemists in Ireland have developed a pair of reactions they think are unique in producing predominantly one of two mirror-image products without a change of catalyst. mark for My Articles similar articles
Chemistry World
March 2, 2007
Philip Ball
Giving Life a Hand Why are proteins left-handed and nucleic acids right-handed? Once offered only a few sketchy theories, scientists have found more alternatives for creating homochirality. mark for My Articles similar articles
Chemistry World
July 27, 2009
Simon Hadlington
Peer review by live blogging Blogging can immediately bring together expert opinion on a given topic. Poorly reviewed papers claiming novelty can be expected to be rapidly dissected in the blogosphere, as some chemists have found out. mark for My Articles similar articles
Chemistry World
November 2, 2015
Batzelladine B Of all the diverse substances that nature produces, the alkaloids -- small molecules containing basic nitrogen -- have had the greatest impact on human history and health. mark for My Articles similar articles
Chemistry World
September 20, 2007
Lewis Brindley
New Catalyst Rings the Changes Organic chemists in the US have developed a method to control the stereochemistry of a useful intramolecular Diels-Alder reaction. mark for My Articles similar articles
Chemistry World
March 28, 2007
Victoria Gill
New Limits Set on Chirality Researchers have set a new standard in stereochemistry. Measuring Raman optical activity, they have confirmed the spatial arrangement of a molecule with almost impossibly subtle chirality: (R)-[ 2H 1, 2H 2, 2H 3]-neopentane. mark for My Articles similar articles
Chemistry World
February 6, 2012
David Bradley
10 out of 10 for boron's coordinated effort A team in the US has created a boron compound that has the highest coordination number of any planar species, squeezing 10 spoke-like bonds from a central metal hub to 10 boron atoms equally spaced around a nanoscopic wheel. mark for My Articles similar articles
Chemistry World
December 4, 2009
James Urquhart
Easier ester synthesis Researchers in the US have shown how oxygen-coated gold nanoparticles can selectively oxidise a variety of alcohols and aldehydes. mark for My Articles similar articles
Chemistry World
July 26, 2007
Tom Westgate
Counterion Does the Twist US chemists have achieved a breakthrough in the design of catalysts that selectively produce chiral compounds. mark for My Articles similar articles
Chemistry World
March 5, 2014
Andy Extance
Rotaxanes make symmetry history A UK team has stumbled upon an efficient way to separately produce each member of an unusual mirror image pair of chemical systems that has eluded scientists for over four decades. mark for My Articles similar articles
Chemistry World
November 2011
Paul Docherty
Column: Totally Synthetic Gelsemoxonine has an extra four-membered azetidine ring, making for a considerable synthetic challenge. mark for My Articles similar articles
Chemistry World
March 2009
Paul Docherty
Column: Totally Synthetic Marine waters have produced some of the biggest celebrities of the natural product world - including the brevitoxins, saxitoxins and tetrodotoxins, 1 famous as much for the sheer human effort needed for their landmark syntheses as for their complexity and size. mark for My Articles similar articles
Chemistry World
February 21, 2008
Lewis Brindley
Esters Made Easy with Indium Indium is the basis of a novel catalyst designed to make useful cyclic esters. This catalyst could greatly simplify the production of chiral dihydropyranones, important structural elements in many natural products and pharmaceuticals. mark for My Articles similar articles
Chemistry World
November 3, 2008
Simon Hadlington
Organic synthesis set for auto-pilot Peptides are routinely made by machines that couple together amino acid components. Could organic synthesis ever get this simple? mark for My Articles similar articles
Chemistry World
November 2, 2015
Tim Wogan
New lithium-air battery safe from water damage A lithium-air battery with superior efficiency and stability has been developed by researchers in the UK. mark for My Articles similar articles
Chemistry World
June 10, 2010
Phillip Broadwith
A green and salty chiral catalyst An efficient, chiral, salt-based hypervalent iodine catalyst has been discovered by Japanese chemists that could replace toxic metal catalysts without generating the waste or explosion risks associated with hypervalent organo-iodine complexes. mark for My Articles similar articles
Chemistry World
March 8, 2011
Jon Cartwright
Carbon nanotubes - a boon for chiral catalysts Researchers in China have created a new catalyst that could help in the production of chiral molecules for medical drugs. The catalyst, which consists of platinum nanoparticles encapsulated in carbon nanotubes, is the most active of its type ever reported. mark for My Articles similar articles
Chemistry World
August 16, 2009
Tom Bond
Catalyst free carbon-carbon bond formation The method offers an environmentally friendly way to form one of the most important bonds in organic synthesis. mark for My Articles similar articles
Chemistry World
May 15, 2012
Harriet Brewerton
Chiral Confusion Scientists in Israel have shown that non-biological chiral crystals are much more abundant than previously thought and their findings could clear up a possible confusion over the term 'chiral'. mark for My Articles similar articles
Chemistry World
July 28, 2014
Tim Wogan
Better batteries with pure lithium anodes Researchers in the US have developed a coating that could allow next generation batteries to have pure lithium anodes. mark for My Articles similar articles
Chemistry World
August 20, 2012
Phillip Broadwith
Fluoroborates Without the Etch A simple, practical method for making popular trifluoroborate reagents without etching glassware or tedious purification procedures has been developed by chemists in the UK. mark for My Articles similar articles
Chemistry World
June 5, 2012
Simon Perks
Chiral separation with micro-flows How do you separate enantiomers without any kind of chiral recognition between molecules? The answer it seems is to use asymmetric flow in a micro-fluidic channel. mark for My Articles similar articles
Chemistry World
April 2010
Paul Docherty
Column: Totally Synthetic When one attempts the first synthesis of a natural product, the set of challenges are often unknown; which intermediates are either inaccessible or unstable, for instance. mark for My Articles similar articles
Chemistry World
May 24, 2013
David Bradley
Microwaves show their hand The chirality of a gas phase molecule held in an electric field can be revealed using microwave spectroscopy. Hooking the technique to a separation step might even be exploited to isolate a specific enantiomer from a racemic mixture of both forms. mark for My Articles similar articles
Chemistry World
December 10, 2014
Emma Stoye
Cutting edge chemistry in 2014 Highlights from last year's ground breaking chemical sciences research. mark for My Articles similar articles