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Chemistry World June 1, 2006 Michael Gross |
New Twists on Catalysis Chemists around the world have discovered several new twists to improve the performance of asymmetric catalysts in hydrogenation reactions. |
Chemistry World May 9, 2010 Phillip Broadwith |
Iron catalyst breaks the mold An iron catalyst that is not only greener than many of its precious metal competitors, but also catalyses reactions that they can't, could open new avenues in transition metal catalysis, say Chinese researchers. |
Chemistry World October 18, 2011 Steve Down |
Cofactor Control of Catalysis Enantioselectivity Scientists have used cofactors to control the enantioselectivity of supramolecular transition metal catalysts, enabling the asymmetric hydrogenation of a series of acrylates and related compounds with remarkably high selectivities. |
Chemistry World May 30, 2013 Andy Extance |
Catalyst duo exerts powerful stereocontrol Chemists from the Swiss Federal Institute of Technology, ETH Zurich, have teamed chiral catalysts in pairs to selectively drive a reaction towards desired stereoisomeric products with high selectivity. |
Chemistry World October 16, 2015 Philippa Matthews |
One pot recipe for incompatible catalytic transformations Researchers from the US have demonstrated a new catalyst support structure allowing two incompatible catalysts to work in tandem. |
Chemistry World March 8, 2011 Jon Cartwright |
Carbon nanotubes - a boon for chiral catalysts Researchers in China have created a new catalyst that could help in the production of chiral molecules for medical drugs. The catalyst, which consists of platinum nanoparticles encapsulated in carbon nanotubes, is the most active of its type ever reported. |
Chemistry World November 7, 2014 Katrina Kramer |
Stressed ligands switch catalysis selectivity Researchers have discovered that enantioselectivity in palladium-catalyzed reactions depends on the ligand's intramolecular strain. |
Chemistry World December 23, 2015 Karl Collins |
Scratching chiral surfaces There are numerous challenges to developing reactions that exploit chiral surfaces, or employ molecular modifiers (ligands) to create a chiral surface environment and control the stereoselectivity of a transformation. |
Chemistry World February 21, 2008 Lewis Brindley |
Esters Made Easy with Indium Indium is the basis of a novel catalyst designed to make useful cyclic esters. This catalyst could greatly simplify the production of chiral dihydropyranones, important structural elements in many natural products and pharmaceuticals. |
Chemistry World April 19, 2009 Hayley Birch |
Chiral metals shape up for catalysis Dutch and Israeli scientists have found a way to induce the chirality usually only found in organic materials in palladium. |
Chemistry World July 20, 2006 Jessica Ebert |
Golden Touch for Amines Aminobenzene chemicals are used to make anything from dyes to pharmaceuticals, and now scientists have found a way to produce them in a more efficient way using a gold catalyst. |
Chemistry World November 28, 2013 Andy Extance |
Base metal catalysts strike hydrogenation gold Three teams have shown that chemists need not rely only on expensive and toxic precious metal catalysts for hydrogenation -- they've found complementary alternatives based on cheap, abundant and safer transition metals. |
Chemistry World September 6, 2006 Michael Gross |
Selective Shortcut Chemists have developed a simple catalyst that speeds up the synthesis of a chiral protected building block used in many complex syntheses. |
Chemistry World November 17, 2008 Simon Hadlington |
Catalyst flexes for extra control US chemists have developed a new type of catalyst capable of exerting high stereochemical control over olefin metathesis reactions |
Chemistry World October 31, 2014 Andy Extance |
Acid choice flips enantioselectivity Organic chemists in Ireland have developed a pair of reactions they think are unique in producing predominantly one of two mirror-image products without a change of catalyst. |
Chemistry World December 17, 2009 Simon Hadlington |
Single catalyst gives two products from racemic mixture Chemists in the US have demonstrated a remarkable reaction in which a single catalyst can transform a racemic mixture - molecules identical in every way except for their chirality - into two distinct enantiomerically pure products. |
Chemistry World February 21, 2007 Tom Westgate |
Complex Organic Molecules Teamed with Iodine Chemists have developed a method for constructing complex halogen-containing organic molecules from simple compounds in a single step. The discovery could pave the way for the synthesis of many potentially useful naturally occurring molecules. |
Chemistry World June 10, 2010 Phillip Broadwith |
A green and salty chiral catalyst An efficient, chiral, salt-based hypervalent iodine catalyst has been discovered by Japanese chemists that could replace toxic metal catalysts without generating the waste or explosion risks associated with hypervalent organo-iodine complexes. |
Chemistry World July 16, 2013 Harriet Brewerton |
Accelerating stereochemical analysis A chemosensor has been developed by scientists in the US to speed up the quantitative stereochemical analysis of chiral amino alcohols and diamines. |
Chemistry World September 20, 2007 Lewis Brindley |
New Catalyst Rings the Changes Organic chemists in the US have developed a method to control the stereochemistry of a useful intramolecular Diels-Alder reaction. |
Chemistry World May 15, 2012 Harriet Brewerton |
Chiral Confusion Scientists in Israel have shown that non-biological chiral crystals are much more abundant than previously thought and their findings could clear up a possible confusion over the term 'chiral'. |
Chemistry World September 22, 2015 Andy Extance |
Firming COFs up takes Michael reaction catalysis forward By making formerly fragile covalent organic frameworks resistant to harsh conditions, researchers have created what they think could be a powerful new catalyst concept. |
Chemistry World December 12, 2007 Jonathan Edwards |
Aqueous Fischer-Tropsch is Clean and Green Chinese chemists have carried out the Fischer-Tropsch reaction in water for the first time, bringing a greener route to hydrocarbon fuels a step closer. |
Chemistry World February 19, 2010 Simon Hadlington |
Forcing stereoselectivity on reactive cations Chemists in the US have devised a dual catalyst strategy to tame the highly reactive iminium ion to give a high degree of stereochemical control over subsequent reactions of the ion. |
Chemistry World June 27, 2013 Emma Eley |
Sustainable iron catalyst for clean hydrogenation An international team of chemists has reported a clean and green way to perform one of the most important industrial reactions for pharmaceutical and petrochemical synthesis. |
Chemistry World March 25, 2011 Simon Hadlington |
New synthesis for chiral anticancer compound The promising anticancer compound nutlin-3 is likely to become more widely available to researchers thanks to a new synthetic protocol developed by US chemists. |
Chemistry World February 6, 2015 Elisabeth Ratcliffe |
Exploiting the chirality of DNA DNA has emerged as an innovative way of controlling the chirality of a reaction product by binding catalysts in such a way that one enantiomer is preferentially generated. |
Chemistry World February 10, 2011 James Urquhart |
Molecular motor controls chirality A single molecule catalytic system that uses a light driven molecular motor to dynamically control the molecule's chiral states has been developed by scientists in the Netherlands. |
Chemistry World September 9, 2011 James Mitchell Crow |
High-throughput catalyst screening for the masses Using nothing more than the standard chemistry lab equipment, researchers in the US have successfully turned the discovery of new catalytic reactions into a high-throughput process. |
Chemistry World October 1, 2014 Karl Collins |
Twisting activity from amides When I think of asymmetric aldol reactions, what immediately springs to mind is using boron to control enolate geometry and chiral auxiliaries to impart facial selectivity in the addition step. |
Chemistry World March 20, 2007 Tom Westgate |
Is Your Lab Ready to go Veggie? In a recently published review article, Geoffrey Cordell demonstrates that the greengrocer's could be an unexpected goldmine of sustainable, cheap reagents that would benefit chemistry in developing countries. |
Chemistry World April 6, 2009 Nina Notman |
Torn catalysts help polymers heal themselves Catalysts that are activated by a mechanical force tearing them in two have been designed by Dutch scientists. |
Chemistry World July 3, 2015 Andy Extance |
Copper catalysis overcomes double bond trouble Some carbon-carbon double bonds seem too unreactive for synthetic use -- but that's just how chemists in the US are now exploiting them. |
Chemistry World April 26, 2007 Richard Van Noorden |
Hydrogen Busters go Synthetic Chemists have created a small molecule which mimics the way natural enzymes chew up hydrogen. The model should inspire designs for new catalysts that can break up hydrogen in fuel cells; or (running in reverse) help produce the fuel for a hydrogen economy. |
Chemistry World March 28, 2007 Victoria Gill |
New Limits Set on Chirality Researchers have set a new standard in stereochemistry. Measuring Raman optical activity, they have confirmed the spatial arrangement of a molecule with almost impossibly subtle chirality: (R)-[ 2H 1, 2H 2, 2H 3]-neopentane. |
Chemistry World April 28, 2010 Mike Brown |
Producing hydrogen from sea water A new catalyst that generates hydrogen from sea water has been developed by scientists in the US. |
Chemistry World March 23, 2009 Hayley Birch |
Speeding up screening for chiral catalysts U.S. researchers say their method represents a 'standard workhorse' for discovery and optimisation of chiral catalysts, such as those widely used by the pharmaceutical and pesticide industries. |
Chemistry World August 2007 Derek Lowe |
Opinion: In the Pipeline Process chemists just don't get the credit they deserve. |
Chemistry World February 13, 2013 James Mitchell Crow |
Tapping proton power for enantioselective synthesis A simple proton is the key to a novel approach by US-based chemists to synthesize chiral amines and alcohols -- a structural motif common to many organic molecules with pharmaceutical promise. |
Chemistry World January 8, 2014 Karl Collins |
Oxidation station Small molecules are making significant inroads -- with reactivity and selectivity approaching levels previously thought unachievable. |
Chemistry World December 18, 2007 James Mitchell Crow |
Cutting-Edge Chemistry in 2007 The important trends, and biggest breakthroughs, of the year's published science papers. |
Chemistry World November 6, 2009 Phillip Broadwith |
Enzyme binds both sides of the mirror European chemists have discovered that both mirror-image forms of a particular compound can bind at the same time in the same site of an enzyme, a phenomenon that has never been seen before. |
Chemistry World April 25, 2014 Derek Lowe |
Engineering serendipity At this stage in the world of organic chemistry, you'd have to think that many of the great reactions that can be stumbled across with known reagents have probably been found. |
Chemistry World February 1, 2006 Michael Gross |
Chiral Catalysis on a Chip Chiral catalysis and analytical separation of the resulting enantiomers can now be performed on a single chip. The process could be scaled up to serve in high throughput screening for new enantioselective catalysts, claim the chemists who developed the chip. |
Chemistry World July 15, 2010 Simon Hadlington |
Synthetic enzyme catalyses Diels-Alder reaction The reaction is key to many organic syntheses and suggests that artificial enzymes could soon become part of the synthetic chemist's toolkit. |
Chemistry World May 26, 2015 Victoria Richards |
Crystalline sponge method strikes again Scientists from Japan report that their revolutionary crystallographic technique has determined the stereochemistries of molecules with axial and planar chiralities, where classical methods had failed. |
Chemistry World March 2, 2007 Philip Ball |
Giving Life a Hand Why are proteins left-handed and nucleic acids right-handed? Once offered only a few sketchy theories, scientists have found more alternatives for creating homochirality. |
Chemistry World June 13, 2008 Richard Van Noorden |
Asymmetric ketone catalysis gets pharma-scale makeover An asymmetric catalysis reaction limited to laboratory syntheses has received a makeover that could see it used on a large scale by drug-makers. |
Chemistry World June 19, 2008 Hepeng Jia |
Chemistry dominates list of China's most influential papers The Thomson Reuters Research Fronts Award recognized a total of 24 key journal articles - including seven chemistry papers and two from the material sciences - for their outstanding contribution to international R&D. |
Chemistry World October 14, 2009 James Urquhart |
New route to amino acids US scientists have found a new way of making a class of non-natural amino acids that are widely used as components of pharmaceuticals and chiral catalysts. |