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Chemistry World June 5, 2012 Simon Perks |
Chiral separation with micro-flows How do you separate enantiomers without any kind of chiral recognition between molecules? The answer it seems is to use asymmetric flow in a micro-fluidic channel. |
Chemistry World May 15, 2012 Harriet Brewerton |
Chiral Confusion Scientists in Israel have shown that non-biological chiral crystals are much more abundant than previously thought and their findings could clear up a possible confusion over the term 'chiral'. |
Reactive Reports May 2007 David Bradley |
Meeting of Molecular Movie Stars New footage confirms Linus Pauling's theory of chemical bonding proposed half a century ago, and could help explain molecular recognition processes important throughout supramolecular chemistry and molecular biology. |
Chemistry World June 25, 2012 Michael Gross |
Running Rings Around Molecular Wires New research could open up the possibility of using new carbon compounds as wires in molecular electronics. |
Chemistry World April 19, 2009 Hayley Birch |
Chiral metals shape up for catalysis Dutch and Israeli scientists have found a way to induce the chirality usually only found in organic materials in palladium. |
Chemistry World March 2, 2007 Philip Ball |
Giving Life a Hand Why are proteins left-handed and nucleic acids right-handed? Once offered only a few sketchy theories, scientists have found more alternatives for creating homochirality. |
Chemistry World July 16, 2013 Harriet Brewerton |
Accelerating stereochemical analysis A chemosensor has been developed by scientists in the US to speed up the quantitative stereochemical analysis of chiral amino alcohols and diamines. |
Chemistry World November 17, 2015 Matthew Gunther |
Rotaxane raises the bar for self-replicating chemical systems Scientists in the UK and Malaysia have created a self-assembling rotaxane that can replicate itself. The result may lead to the development of autonomous chemical systems that mimic cellular processes. |
Chemistry World September 26, 2014 Jennifer Newton |
James Crowley: Magicians rings and dumbbells on a molecular scale Research in Crowley's group combines synthetic organic, inorganic, organometallic and supramolecular chemistry to design and synthesize new functional materials. |
Chemistry World November 3, 2011 Erica Wise |
A Model for the Single Chirality of Life The boiling solutions in prebiotic hot springs could shed light on the emergence of a single chiral form of biomolecules in nature, say Spanish scientists. |
Chemistry World January 6, 2015 Jennifer Newton |
Light drives unusual rotaxane-to-catenane transformation Researchers in Europe have reported a mechanically-interlocked molecular system that can reversibly switch between being a rotaxane and a catenane. |
Chemistry World August 7, 2011 Phillip Broadwith |
Possible Origin of Chirality in the Rna World Given a tiny push one way or the other, simple racemic precursors can lead to the chiral building blocks of RNA using a combination of chemical and physical factors. |
Chemistry World March 28, 2007 Victoria Gill |
New Limits Set on Chirality Researchers have set a new standard in stereochemistry. Measuring Raman optical activity, they have confirmed the spatial arrangement of a molecule with almost impossibly subtle chirality: (R)-[ 2H 1, 2H 2, 2H 3]-neopentane. |
Chemistry World September 17, 2008 Hayley Birch |
Colloids twist like DNA French scientists have used magnetic colloids to make self-assembling, helical structures reminiscent of DNA |
Chemistry World February 6, 2015 Elisabeth Ratcliffe |
Exploiting the chirality of DNA DNA has emerged as an innovative way of controlling the chirality of a reaction product by binding catalysts in such a way that one enantiomer is preferentially generated. |
Chemistry World February 21, 2007 Tom Westgate |
Complex Organic Molecules Teamed with Iodine Chemists have developed a method for constructing complex halogen-containing organic molecules from simple compounds in a single step. The discovery could pave the way for the synthesis of many potentially useful naturally occurring molecules. |
Chemistry World November 26, 2010 Amaya Camara-Campos |
Enriching the origin of life theory An enantioenrichment of the amino acid valine, which could shed light on the origin of chirality on Earth, has been achieved by scientists in Spain. |
Chemistry World July 26, 2007 Tom Westgate |
Counterion Does the Twist US chemists have achieved a breakthrough in the design of catalysts that selectively produce chiral compounds. |
Chemistry World July 24, 2009 Nina Notman |
Chiral isotropic liquids from achiral molecules Boomerang-shaped liquid crystal phase molecules that don't exhibit 'handedness' (chirality) have been found to form unusual chiral structures that spontaneously separate into left- and right-handed domains. |
Chemistry World July 30, 2013 Paul Docherty |
Melotenine A Chirality, where would we be without you? Often the bane of the synthetic chemist's life, the challenge of asymmetry is perhaps what makes total synthesis so endlessly intriguing. |
Chemistry World November 6, 2009 Phillip Broadwith |
Enzyme binds both sides of the mirror European chemists have discovered that both mirror-image forms of a particular compound can bind at the same time in the same site of an enzyme, a phenomenon that has never been seen before. |
Chemistry World November 1, 2009 Hayley Birch |
How light gave life a helping hand A new theory for how 'handedness' in organic molecules evolved has been proposed by Dutch scientists. |
Chemistry World December 17, 2009 Simon Hadlington |
Single catalyst gives two products from racemic mixture Chemists in the US have demonstrated a remarkable reaction in which a single catalyst can transform a racemic mixture - molecules identical in every way except for their chirality - into two distinct enantiomerically pure products. |
Chemistry World September 6, 2013 Melissae Fellet |
Unravelling stereochemistry via mass spectrometry Researchers have used mass spectrometry to determine the stereochemistry of a prototypical chiral molecule, CHBrClF. |
Chemistry World March 8, 2011 Jon Cartwright |
Carbon nanotubes - a boon for chiral catalysts Researchers in China have created a new catalyst that could help in the production of chiral molecules for medical drugs. The catalyst, which consists of platinum nanoparticles encapsulated in carbon nanotubes, is the most active of its type ever reported. |
Chemistry World April 29, 2009 James Urquhart |
Huge pores in zeolite molecular sieve Researchers in Spain and Sweden have synthesized and structurally determined a new kind of crystalline molecular sieve with extra large holes and chiral properties. |
Chemistry World May 26, 2015 Victoria Richards |
Crystalline sponge method strikes again Scientists from Japan report that their revolutionary crystallographic technique has determined the stereochemistries of molecules with axial and planar chiralities, where classical methods had failed. |
Chemistry World September 25, 2014 Hayley Simon |
Breakup reaction hints at handedness of nature The breakup of 3-bromocamphor molecules bombarded by polarized electrons has given a tantalizing hint of the origins of biological homochirality -- nature's preference for one mirror image of a molecule over another. |
Chemistry World May 30, 2013 Andy Extance |
Catalyst duo exerts powerful stereocontrol Chemists from the Swiss Federal Institute of Technology, ETH Zurich, have teamed chiral catalysts in pairs to selectively drive a reaction towards desired stereoisomeric products with high selectivity. |
Chemistry World June 15, 2015 Tim Wogan |
Long range chirality transfer observed A new method to detect biomolecules by using a plasmonic nanoparticle to transfer their chirality onto an achiral dye has been developed by researchers |
Chemistry World December 10, 2008 Simon Hadlington |
Alcohol enantiomer conundrum cracked UK chemists have discovered a straightforward new way to make chiral tertiary alcohols that gives selective access to either enantiomer. |
Chemistry World May 9, 2010 Phillip Broadwith |
Iron catalyst breaks the mold An iron catalyst that is not only greener than many of its precious metal competitors, but also catalyses reactions that they can't, could open new avenues in transition metal catalysis, say Chinese researchers. |
Chemistry World September 20, 2007 Lewis Brindley |
New Catalyst Rings the Changes Organic chemists in the US have developed a method to control the stereochemistry of a useful intramolecular Diels-Alder reaction. |
Chemistry World May 24, 2013 David Bradley |
Microwaves show their hand The chirality of a gas phase molecule held in an electric field can be revealed using microwave spectroscopy. Hooking the technique to a separation step might even be exploited to isolate a specific enantiomer from a racemic mixture of both forms. |
Chemistry World April 28, 2009 Jon Cartwright |
Metal ions give rise to threaded molecules Chemists in France have developed a simple method to synthesize tricky '[3]rotaxane' molecules for potential applications in intelligent materials and molecular machines. |
Chemistry World October 18, 2011 Steve Down |
Cofactor Control of Catalysis Enantioselectivity Scientists have used cofactors to control the enantioselectivity of supramolecular transition metal catalysts, enabling the asymmetric hydrogenation of a series of acrylates and related compounds with remarkably high selectivities. |
Chemistry World June 2010 Paul Docherty |
Column: Totally Synthetic Although its chemistry is mature and varied, my use of silicon reagents in my synthetic forays has been limited to a somewhat clumsy use of hydroxyl protecting groups. |
Chemistry World January 24, 2007 Lionel Milgrom |
Chemical Computing Creates World's Densest Data Storage Medium A vital piece of nanoelectronic circuitry has been produced which could bring molecular computers a step closer. |
Chemistry World June 10, 2010 Phillip Broadwith |
A green and salty chiral catalyst An efficient, chiral, salt-based hypervalent iodine catalyst has been discovered by Japanese chemists that could replace toxic metal catalysts without generating the waste or explosion risks associated with hypervalent organo-iodine complexes. |
Chemistry World June 17, 2010 Andrew Turley |
Biocatalyst improves diabetes drug production Researchers have developed an enzyme that can produce a difficult to form chiral amine in a best-selling diabetes therapy. |
Chemistry World June 13, 2008 Richard Van Noorden |
Asymmetric ketone catalysis gets pharma-scale makeover An asymmetric catalysis reaction limited to laboratory syntheses has received a makeover that could see it used on a large scale by drug-makers. |
Chemistry World June 18, 2014 Michael Parkin |
Separation by levitation A team in the US has shown that enantiopure and racemic crystals can be separated by magnetic levitation. |
Chemistry World November 2, 2015 |
Batzelladine B Of all the diverse substances that nature produces, the alkaloids -- small molecules containing basic nitrogen -- have had the greatest impact on human history and health. |
Chemistry World March 23, 2009 Hayley Birch |
Speeding up screening for chiral catalysts U.S. researchers say their method represents a 'standard workhorse' for discovery and optimisation of chiral catalysts, such as those widely used by the pharmaceutical and pesticide industries. |
Chemistry World June 16, 2010 Simon Hadlington |
Rotaxane molecule seen in action Researchers from the US and Japan have directly observed the ring of a rotaxane molecule shuttling along its spindle. The behaviour of the rotaxane is influenced by its molecular environment, something that is significant if the molecules are to be used as molecular machines. |
Chemistry World February 21, 2008 Lewis Brindley |
Esters Made Easy with Indium Indium is the basis of a novel catalyst designed to make useful cyclic esters. This catalyst could greatly simplify the production of chiral dihydropyranones, important structural elements in many natural products and pharmaceuticals. |
Reactive Reports Issue 33 David Bradley |
Two-faced Liquid Crystals A new class of programmable liquid crystals could be used to make variable optical filters for laboratory instrumentation and digital cameras; they might even be used to treat dyslexia. |
Chemistry World April 18, 2010 Simon Hadlington |
First DNA rotaxane Rotaxanes are dumbbell-shaped molecules encircled by a molecular hoop that can move unhindered along the axle, trapped by the bulky stoppers at either end. These could be useful components in molecular machines. |
Chemistry World September 6, 2006 Michael Gross |
Selective Shortcut Chemists have developed a simple catalyst that speeds up the synthesis of a chiral protected building block used in many complex syntheses. |
Chemistry World May 15, 2014 Jenifer Mizen |
Freeze-dried cells make better biocatalysts A biocatalytic cascade using mashed-up cells has overcome extraction and solubility problems associated with using enzymes in chemical syntheses. |