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Chemistry World October 4, 2006 Bea Perks |
Good Year for RNA Roger Kornberg, professor of structural biology at Stanford University, has been awarded the 2006 Nobel prize in chemistry for his work on the molecular basis of transcription. |
Chemistry World November 2006 Bea Perks |
Call That Chemistry? This year's Nobel prize in chemistry was a tour de force for crystallography, underscoring the vital role chemistry plays across the sciences. |
Chemistry World November 2009 |
Biology's Nobel molecule factory Three scientists who revealed the structure and workings of the ribosome have shared the 2009 Nobel prize in chemistry. |
HHMI Bulletin Spring 2013 Sarah C.P. Williams |
Sounding the Alarm Details on how cells detect and respond to foreign DNA may provide clues to autoimmune diseases. |
IEEE Spectrum March 2011 Lucks & Arkin |
Synthetic Biology's Hunt for the Genetic Transistor How genetic circuits will unlock the true potential of bioengineering |
Chemistry World October 2, 2006 Bea Perks |
RNAi Pioneers Win Nobel Prize for Medicine Molecular biologists Andrew Fire and Craig Mello have been awarded this year's Nobel prize in physiology or medicine for their discovery of RNA interference. |
Scientific American November 2007 Ed Regis |
The Forgotten Code Cracker In the 1960s Marshall W. Nirenberg deciphered the genetic code, the combination of the A, T, G and C nucleotides that specify amino acids. So why do people think that Francis Crick did it? |
Chemistry World November 16, 2006 Simon Hadlington |
Gene-Reading Enzyme Catapulted by Scrunch Power Two teams of researchers have solved a conundrum that has baffled molecular biologists for 20 years -- how the enzyme responsible for `reading' genes can release itself from the portion of DNA to which it initially binds extremely tightly. |
Chemistry World February 2011 |
My hero: The greatest influences of chemistry Nobel laureates Aaron Ciechanover, who won the 2004 Nobel prize in chemistry with Avram Hershko and Irwin Rose for the discovery of ubiquitin-mediated protein degradation, talks about Charles Darwin. |
HHMI Bulletin May 2010 Robert Tjian |
Biomolecular Crowdsourcing A generation of web-savvy entrepreneurs has found a relatively cheap and effective approach to solving complex problems and soliciting ideas: toss out a challenge into a vibrant digital community and watch what happens. |
Chemistry World October 19, 2015 Matthew Gunther |
The house that DNA built The 2015 chemistry Nobel prize was awarded to Tomas Lindahl, Paul Modrich and Aziz Sancar for DNA repair. |
Chemistry World October 7, 2015 Matthew Gunther |
DNA repair research takes the 2015 chemistry Nobel The 2015 Nobel Prize in chemistry has been awarded to Tomas Lindahl, Paul Modrich and Aziz Sancar for unraveling how cells deal with DNA damage. |
Chemistry World May 12, 2008 Simon Hadlington |
'Super-yeast' tackles unnatural proteins Researchers in the US have engineered yeast cells to produce large amounts of proteins containing unnatural amino acids (UAAs) - a feat that has previously only been possible with bacteria. |
BusinessWeek July 19, 2004 Catherine Arnst |
James Watson and Francis Crick: Cracking The Code Of Life The 1953 discovery of the molecular structure of deoxyribonucleic acid, the building block of all life, transformed biology. And the Cold War and male chauvinism played roles in solving the DNA riddle |
Chemistry World May 2008 Philip Ball i |
Pulling our strings There is much more to DNA than that elegant double helix. The author explores the twists and tangles of chromatin. |
Salon.com December 19, 2000 Carolyn McConnell |
"The Century of the Gene" by Evelyn Fox Keller A new book argues that there may be no such thing as a gene. At least, it has proved very difficult to isolate a discrete physical item that can do the work our notion of the gene does... |
Chemistry World October 31, 2008 Manisha Lalloo |
DNA-rewinding protein discovered US scientists have found an enzyme that rewinds sections of DNA whose strands have mistakenly come apart. |
Bio-IT World April 15, 2003 |
Elementary, My Dear Watson The world celebrates the golden anniversary of the double helix. |
HHMI Bulletin Spring 2013 Nicole Kresge |
A Structural Toolbox Natalie Strynadka wants to design a better antibiotic. Her strategy: learn about the molecules bacteria use to invade cells. Her tool: structural biology. |
HHMI Bulletin February 2012 Sarah C.P. Williams |
The Twists and Turns of Immunity Fred Alt has built a career making sense of the immune system -- specifically, the diverse antibodies that fight off invading molecules, from viruses to cancer cells to pollen. |
HHMI Bulletin Winter 2013 Megan Scudellari |
Tunneling Out A research team including HHMI investigator Melissa Moore at the University of Massachusetts Medical School has discovered an alternative passageway used by RNA -- protein complexes to exit the nucleus. |
Chemistry World August 2007 Philip Ball |
Opinion: The Crucible The twist on DNA |
HHMI Bulletin Winter 2013 Nicole Kresge |
A Time to Transcribe Circadian clocks control significant bodily functions: sleeping and feeding patterns, blood pressure, hormone production, body temperature, brain activity. Now, HHMI investigator Joseph Takahashi at the University of Texas Southwestern Medical Center is adding genome-wide transcription to that list. |
The Motley Fool October 5, 2006 Ralph Casale |
RNAi: Nobel Prize-Winning Biotechnology While drugs based on RNAi knockdown technology may have the potential to become the next big thing in biotechnology, they are still a long way from becoming FDA-approved marketable entities. But it's never too soon to start keeping an eye on the future. Investors, take note. |
HHMI Bulletin February 2011 Mitzi Baker |
When Worlds Collide The right time and place led to a new RNAi-like pathway in bacteria for biochemist Jennifer Doudna and geobiologist Jill Banfield. |
Technology Research News May 5, 2004 Kimberly Patch |
DNA Bot Targets Cancer Researchers from Israel have constructed a molecular-size computer that is programmed to find signs of cancer cells, and when they are present, dispense DNA molecules designed to eradicate those cells. |
Scientific American January 2006 Charles Q. Choi |
Un-Killing the Messenger Processing bodies do more than serve as RNA trash bins in cells. Research now suggests that these P-bodies are less like junkyards and more like office centers, where messages are amassed, silenced and reactivated. |
Chemistry World March 21, 2013 Phillip Broadwith |
AstraZeneca partners with Moderna for $240 million Moderna has developed a way to use messenger RNA (mRNA), the molecule cells use to turn DNA into proteins, to stimulate the production of specific proteins in cells where disease has diminished or eliminated their ability to do so. |
Chemistry World April 7, 2011 Laura Howes |
Long chains give new life to RNA world hypothesis The so-called RNA world hypothesis has gained fresh momentum with the synthesis of the longest lab grown RNA strands made using an enzyme that is itself made of RNA, an 'RNAzyme'. |
Chemistry World March 15, 2007 Henry Nicholls |
The Mother of All Enzymes Scientists have uncovered the three-dimensional structure of what might be biology's first enzyme. This sheds light on the chemistry at a key moment in the origin of life, they argue. |
Chemistry World April 19, 2012 Andy Extance |
Polymers perform non-DNA evolution Scientists have found that six polymer alternatives to DNA can pass on genetic information, and have evolved one type to specifically bind target molecules. |
Scientific American June 2005 JR Minkel |
RNA to the Rescue The spectacular discovery that a species of plant can summon up genes its parents have lost highlights biologists' increasing recognition of RNA as a more versatile and important molecule in its own right. |
HHMI Bulletin February 2012 Sarah C. P. Williams |
Force Factor In the context of cells, forces are required to move molecules. Quantifying these forces gives scientists a way to compare and contrast different molecular motors. |
Bio-IT World April 15, 2003 Malorye Branca |
Beyond the Blueprint How will the wealth of data emanating from the human genome and allied technologies impact research on health and disease? |
Chemistry World March 1, 2011 Catherine Bacon |
Unravelling chromosomes Danish scientists have used a micro device to isolate centimetre-long portions of human DNA to help study the genetic make-up of diseased cells. |
Chemistry World January 8, 2012 David Bradley |
The TNA world that came before the RNA one Once it was recognised that DNA is key to the molecular self-replication that underpins life, chemists have sought to understand the origins of this double-helical molecule in that primordial age. |
Chemistry World October 19, 2009 Simon Hadlington |
DNA stretching mystery solved A detailed understanding of the elastic properties of DNA can give scientists key insights into interactions of DNA and the proteins that carry out these manipulations. |
HHMI Bulletin Feb 2011 |
DNA Curtains How proteins behave in such a crash test gives scientists data about their structural integrity, how they attach to DNA, and how they behave in a cell. |
Chemistry World January 11, 2008 John Bonner |
DNA Nanoparticles Detect Gene Expression US scientists have made nanoparticles from DNA that they say could be used to identify the genes being expressed in a single cell. |
Chemistry World October 13, 2015 Simon Hadlington |
DNA movement through motor proteins measured Researchers have adapted a method for DNA sequencing to measure directly and with exquisite sensitivity the movement of a single molecule of DNA as it is drawn through specialized motor proteins. |
Chemistry World May 7, 2014 Emma Stoye |
Bacterium survives unnatural DNA transplant The first organism that can grow and replicate with an unnatural base pair in its DNA -- giving the cell six nucleotides instead of the usual four -- has been created by scientists in the US. |
Chemistry World July 17, 2012 Simon Perks |
Synthetic nanozymes silence hepatitis C Researchers at the University of Florida, US, have discovered that an artificial nanoparticle complex, known as a nanozyme, can help to treat viral infections by 'shutting off' their genetic material. |
Chemistry World February 27, 2006 Michael Gross |
A DNA Switch for RNA Folding Researchers have equipped a large RNA domain with a DNA switch, which they say can fold or unfold the RNA molecule at will. |
Chemistry World October 1, 2014 Michael Gross |
Viruses melt 'glassy' DNA US Researchers have identified the factors that enable viral DNA to turn from solid to liquid, which allows them to infect host cells. They say the process could become a target for new antiviral therapies. |
Chemistry World January 30, 2014 Anthony King |
Unnatural DNA links click for faster synthesis Human cells can still read strands of DNA correctly if they are stitched together using linkers not found in nature, a new study shows. |
Chemistry World December 20, 2010 Jennifer Newton |
Frozen assets in biobanks Scientists from Sweden have devised a technique that extracts both DNA and RNA from frozen tissue in a bid to improve large-scale extractions from samples stored in biobanks, which could aid cancer research. |
Chemistry World January 28, 2011 David Barden |
Chips make short work of RNA synthesis Chinese scientists have developed a much easier way to make the short strands of RNA that are an essential tool in understanding what genes do. |
Wired August 21, 2007 |
Three Smart Things About Genomics 1. The real benefit of studying genomes is that it has taught us how little we know... 2. Genomics' reductionist approach has become more holistic... etc. |
Reactive Reports Apr/May 2005 David Bradley |
At Last, the Structure of DNA Researchers have made a significant advance in our understanding of life's main molecule, using X-ray crystallography to determine the three-dimensional structures of nearly all the possible sequences of a macromolecule. |
Scientific American September 2008 Melinda Wenner |
Rethinking the Wrinkling: Key Genes Cause Aging Key genes, rather than cell and DNA damage, as causes of aging. |