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Scientific American
January 2006
Charles Q. Choi
Un-Killing the Messenger Processing bodies do more than serve as RNA trash bins in cells. Research now suggests that these P-bodies are less like junkyards and more like office centers, where messages are amassed, silenced and reactivated. mark for My Articles similar articles
HHMI Bulletin
Winter 2013
Sarah C.P. Williams
Cellular Search Engine Craig Mello's lab has now uncovered the reason piRNA molecules are so ubiquitous and exist in so many forms in C. elegans: so they can pair with essentially any genetic sequence they encounter during their endless scanning. mark for My Articles similar articles
Chemistry World
August 8, 2012
Protein Coat for Gene Therapy Kenneth Woycechowsky's group at the University of Utah has modified a non-viral protein so that it will carry RNA. mark for My Articles similar articles
Chemistry World
October 2, 2006
Bea Perks
RNAi Pioneers Win Nobel Prize for Medicine Molecular biologists Andrew Fire and Craig Mello have been awarded this year's Nobel prize in physiology or medicine for their discovery of RNA interference. mark for My Articles similar articles
Chemistry World
April 19, 2011
Simon Hadlington
Cell factories package drugs for delivery Scientists in Australia and Germany have used living cells as 'factories' to encapsulate particles such as drugs in biological membranes. mark for My Articles similar articles
HHMI Bulletin
May 2012
Nicole Kresge
Locating a Genetic Glitch A team of 41 scientists led by HHMI investigator Louis Ptacek has pinpointed the gene responsible for a rare disease that causes sudden, uncontrollable movements. The culprit is a little known protein that may be responsible for communication between neurons. mark for My Articles similar articles
HHMI Bulletin
Spring 2013
Sarah C.P. Williams
Sounding the Alarm Details on how cells detect and respond to foreign DNA may provide clues to autoimmune diseases. mark for My Articles similar articles
Chemistry World
June 9, 2008
Simon Hadlington
Artificial virus silences genes Scientists in Korea have created an artificial virus that can target the nucleus of cancer cells and knock out specific genes. mark for My Articles similar articles
Chemistry World
September 1, 2008
James Mitchell Crow
Drug discovery on a chip Scientists in the US have, for the first time, used microfluidics to discover drug leads. The team's lab-on-a-chip device revealed inhibitors of a key membrane-bound protein in hepatitis C virus mark for My Articles similar articles
Technology Research News
March 12, 2003
RNA forms nanomotor Researchers from Purdue University have constructed a tiny motor from DNA and RNA molecules. The device, fueled by ATP, which powers our own movements, could eventually power nanomachines. mark for My Articles similar articles
Chemistry World
March 21, 2010
Simon Hadlington
Nanoparticles successfully deliver RNA interference in cancer patients The system aims to exploit the phenomenon of RNA interference, where short sequences of double-stranded RNA, called small interfering RNA or siRNA, can trigger the disruption of the manufacture of certain proteins in a cell. mark for My Articles similar articles
Chemistry World
July 17, 2012
Simon Perks
Synthetic nanozymes silence hepatitis C Researchers at the University of Florida, US, have discovered that an artificial nanoparticle complex, known as a nanozyme, can help to treat viral infections by 'shutting off' their genetic material. mark for My Articles similar articles
Reactive Reports
October 2006
David Bradley
RNA Chemistry Zips Up Nobel Prize If Watson and Crick unlocked the mystery of DNA's structure, then Stanford University's Roger Kornberg and his team unzipped the secret of how the cell converts DNA into the RNA needed to make proteins. mark for My Articles similar articles
HHMI Bulletin
February 2011
Sarah C.P. Williams
Enforcing Order Changing the spatial arrangement of molecules in a cell can alter their functions. mark for My Articles similar articles
Chemistry World
November 27, 2007
James Mitchell Crow
A Flare for Gene Silencing US scientists have developed nanoparticle probes coated with DNA that release fluorescent 'flares' when they silence genes inside cells. mark for My Articles similar articles
Chemistry World
August 7, 2008
Simon Hadlington
RNA stops HIV in its tracks Scientists have successfully used a biochemical Trojan horse to smuggle killer sequences of RNA into immune cells to mug invading HIV, stopping infection in its tracks mark for My Articles similar articles
HHMI Bulletin
February 2012
Sarah C. P. Williams
Force Factor In the context of cells, forces are required to move molecules. Quantifying these forces gives scientists a way to compare and contrast different molecular motors. mark for My Articles similar articles
Wired
August 2005
Jonathon Keats
The Deadly Art of Viral Cinema Her studio is a biophysics lab, her camera a microscope. And she's changing the way we see - and fight - disease. Zhuang uses lasers, a microscope, and pair of hi-res digicams to capture viral infection in action. mark for My Articles similar articles
Managed Care
November 2003
Thomas Morrow
Making Sense of Antisense and Interference Treatments that interfere with protein synthesis at the cellular level will soon be debated in medical policy committee meetings. mark for My Articles similar articles
Chemistry World
October 1, 2014
Michael Gross
Viruses melt 'glassy' DNA US Researchers have identified the factors that enable viral DNA to turn from solid to liquid, which allows them to infect host cells. They say the process could become a target for new antiviral therapies. mark for My Articles similar articles
HHMI Bulletin
Aug 2011
Cassandra Willyard
A Faster Knockout With a virus, a needle, and an ultrasound machine, researchers have drastically cut the time it takes to disable a gene in mice. mark for My Articles similar articles
Chemistry World
June 27, 2010
Simon Hadlington
Nanoparticles allow remote control of cells In an experiment reminiscent of the mind-control rays that featured prominently in B-movies from the 1950s, scientists in the US have used a magnetic field to alter the behavior of an animal. mark for My Articles similar articles
Chemistry World
October 21, 2010
Studies Probe Key Flu Protein New details about the structure of an influenza protein that is a key drug target have been revealed in separate studies by groups in the US. The two studies provide insights into the workings of the protein machinery that the virus needs to infect cells. mark for My Articles similar articles
HHMI Bulletin
Spring 2013
Nicole Kresge
Use It or Lose It HHMI investigator Catherine Dulac of Harvard University has uncovered a small molecule that plays a big role in the process of tuning olfactory neurons to the environment. mark for My Articles similar articles
Chemistry World
May 12, 2008
Simon Hadlington
'Super-yeast' tackles unnatural proteins Researchers in the US have engineered yeast cells to produce large amounts of proteins containing unnatural amino acids (UAAs) - a feat that has previously only been possible with bacteria. mark for My Articles similar articles
Chemistry World
April 20, 2009
James Urquhart
New method reveals small molecule-RNA conjugates US scientists using novel chemical screening methods have discovered a new class of small molecules connected to RNA, suggesting that cellular RNA may be more chemically diverse than previously thought. mark for My Articles similar articles
Technology Research News
January 12, 2005
RNA Tiles Form Nanopatterns Researchers have developed a method of coaxing artificial RNA molecules to self-assemble into specific shapes, much like a jigsaw puzzle automatically assembling. The structures could eventually be used as templates for nanochips, nanocircuits and nanocrystals mark for My Articles similar articles
Chemistry World
February 12, 2014
Manisha Lalloo
Synthetic strategy targets 'undruggable' small RNAs Chemists in the US have found a way to predict small molecules that can target short pieces of RNA involved in some diseases, such as cancer. mark for My Articles similar articles
HHMI Bulletin
Spring 2013
Nicole Kresge
A Structural Toolbox Natalie Strynadka wants to design a better antibiotic. Her strategy: learn about the molecules bacteria use to invade cells. Her tool: structural biology. mark for My Articles similar articles
Chemistry World
October 31, 2010
Michael Gross
Kiss of death for cancer cells Scientists have deciphered the surprising structure of the perforin pore, which delivers the 'kiss of death' to virus-infected cells and cancer cells in the body. mark for My Articles similar articles
HHMI Bulletin
Winter 2013
Nicole Kresge
A Structural Revolution Over the years, scientists and artists have used an assortment of techniques to showcase molecular structure. mark for My Articles similar articles
Chemistry World
September 23, 2009
Simon Hadlington
Direct route to RNA sequences Scientists in the US appear to have cracked a major problem in molecular biology: how to sequence single molecules of RNA directly. mark for My Articles similar articles
Chemistry World
October 20, 2008
Hayley Birch
RNA computers built in yeast US scientists have assembled ribonucleic acids into an adaptable logic system that can be programmed to sense and respond to molecules inside living yeast cells. mark for My Articles similar articles
Chemistry World
August 10, 2015
Kira Welter
Peptide glue may have held first protocell components together Electrostatic interactions induced by short, positively charged, hydrophobic peptides are all it takes to attach RNA to vesicle membranes. mark for My Articles similar articles
IEEE Spectrum
August 2006
Schoenbach et al.
Zap Extreme voltage could be a surprisingly delicate tool in the fight against cancer. The list of effects that scientists have achieved using nanoseconds-long pulses is growing rapidly, though their actual use as a medical treatment is still years away. mark for My Articles similar articles
HHMI Bulletin
February 2012
Nicole Kresge
Protein Precision in the Brain with CSF Two causes of autism arise from opposite cellular mechanisms. Too much or too little protein production at the synapse between neurons can cause autism and intellectual disability. mark for My Articles similar articles
Chemistry World
October 4, 2006
Bea Perks
Good Year for RNA Roger Kornberg, professor of structural biology at Stanford University, has been awarded the 2006 Nobel prize in chemistry for his work on the molecular basis of transcription. mark for My Articles similar articles
Popular Mechanics
September 2006
Ben Harder
Seeking Immunity Pathogens like West Nile virus show no respect for borders. But a new class of vaccines may soon keep them in check. mark for My Articles similar articles
The Motley Fool
July 11, 2007
Brian Orelli
Everybody Loves RNAi Roche is the latest firm to (over)pay for the hottest new drug technology. Alnylam announced that it licensed some of its intellectual property to Roche for $331 million. Investors, take note. mark for My Articles similar articles
Scientific American
June 2005
JR Minkel
RNA to the Rescue The spectacular discovery that a species of plant can summon up genes its parents have lost highlights biologists' increasing recognition of RNA as a more versatile and important molecule in its own right. mark for My Articles similar articles
Chemistry World
December 5, 2007
Ananyo Bhattacharya
Structural Snapshot Shows Monster Protein A structural snapshot of a protein capsule has revealed details of the largest cellular component ever imaged by x-ray crystallography. mark for My Articles similar articles
Chemistry World
January 20, 2011
Hayley Birch
Programmable RNA promising for bio-compatible therapies Programmable nanostructures based on ribonucleic acid could be used as vessels for shipping therapeutic molecules into cells, according to US scientists. mark for My Articles similar articles
Chemistry World
January 11, 2008
John Bonner
DNA Nanoparticles Detect Gene Expression US scientists have made nanoparticles from DNA that they say could be used to identify the genes being expressed in a single cell. mark for My Articles similar articles
HHMI Bulletin
Aug 2010
Richard Saltus
Three-Dimensional Cell Cultures Thinking big but starting small, Sangeeta Bhatia is closing in on her ambitious goal: growing human livers in the lab from scratch. mark for My Articles similar articles
Chemistry World
November 2006
Bea Perks
Call That Chemistry? This year's Nobel prize in chemistry was a tour de force for crystallography, underscoring the vital role chemistry plays across the sciences. mark for My Articles similar articles
IEEE Spectrum
March 2011
Lucks & Arkin
Synthetic Biology's Hunt for the Genetic Transistor How genetic circuits will unlock the true potential of bioengineering mark for My Articles similar articles
Chemistry World
January 31, 2008
John Bonner
RNAi Scores Victory Against Crohn's Disease in Mice Thousands of people suffering from the debilitating gut condition Crohn's disease could experience relief from their symptoms through a technique that blocks production of a key protein in the inflammation process. mark for My Articles similar articles
Chemistry World
March 21, 2013
Phillip Broadwith
AstraZeneca partners with Moderna for $240 million Moderna has developed a way to use messenger RNA (mRNA), the molecule cells use to turn DNA into proteins, to stimulate the production of specific proteins in cells where disease has diminished or eliminated their ability to do so. mark for My Articles similar articles
Chemistry World
August 15, 2007
John Bonner
Chemists Claim Biological Alchemy South Korean chemists say they have turned muscle cells from the sole of a human foot into something akin to stem cells, using a simple molecule called neurodazine. mark for My Articles similar articles
Chemistry World
July 6, 2007
Michael Gross
Predicting How Proteins Fold Researchers in Italy and the UK have now developed a computational approach that can simulate the folding of membrane proteins in atomic detail. mark for My Articles similar articles