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HHMI Bulletin Nov 2011 Nicole Kresge	Bacterial -- Viral Warfare with CSF When bacteria survive a run-in with a virus or phage, they take some of the invader's DNA and integrate it into their own genome to help combat future attacks.
HHMI Bulletin Nov 2011 Dave Mosher	A New PACE for Laboratory Evolution Researchers have found a way to accelerate evolution of molecules by harnessing viruses.
HHMI Bulletin Winter 2013 Sarah C.P. Williams	Cellular Search Engine Craig Mello's lab has now uncovered the reason piRNA molecules are so ubiquitous and exist in so many forms in C. elegans: so they can pair with essentially any genetic sequence they encounter during their endless scanning.
Chemistry World October 2, 2006 Bea Perks	RNAi Pioneers Win Nobel Prize for Medicine Molecular biologists Andrew Fire and Craig Mello have been awarded this year's Nobel prize in physiology or medicine for their discovery of RNA interference.
IEEE Spectrum March 2011 Lucks & Arkin	Synthetic Biology's Hunt for the Genetic Transistor How genetic circuits will unlock the true potential of bioengineering
Chemistry World November 2006 Bea Perks	Call That Chemistry? This year's Nobel prize in chemistry was a tour de force for crystallography, underscoring the vital role chemistry plays across the sciences.
Chemistry World October 31, 2008 Manisha Lalloo	DNA-rewinding protein discovered US scientists have found an enzyme that rewinds sections of DNA whose strands have mistakenly come apart.
Chemistry World July 17, 2012 Simon Perks	Synthetic nanozymes silence hepatitis C Researchers at the University of Florida, US, have discovered that an artificial nanoparticle complex, known as a nanozyme, can help to treat viral infections by 'shutting off' their genetic material.
HHMI Bulletin Spring 2013 Sarah C.P. Williams	Sounding the Alarm Details on how cells detect and respond to foreign DNA may provide clues to autoimmune diseases.
Bio-IT World July 15, 2003 Malorye Branca	Silence Is Golden RNA interference's scientific, therapeutic, and economic potential is unquestionable, but some sticky questions still remain.
Chemistry World April 7, 2011 Laura Howes	Long chains give new life to RNA world hypothesis The so-called RNA world hypothesis has gained fresh momentum with the synthesis of the longest lab grown RNA strands made using an enzyme that is itself made of RNA, an 'RNAzyme'.
Chemistry World February 27, 2006 Michael Gross	A DNA Switch for RNA Folding Researchers have equipped a large RNA domain with a DNA switch, which they say can fold or unfold the RNA molecule at will.
Chemistry World November 16, 2006 Simon Hadlington	Gene-Reading Enzyme Catapulted by Scrunch Power Two teams of researchers have solved a conundrum that has baffled molecular biologists for 20 years -- how the enzyme responsible for `reading' genes can release itself from the portion of DNA to which it initially binds extremely tightly.
Scientific American June 2005 JR Minkel	RNA to the Rescue The spectacular discovery that a species of plant can summon up genes its parents have lost highlights biologists' increasing recognition of RNA as a more versatile and important molecule in its own right.
Managed Care November 2003 Thomas Morrow	Making Sense of Antisense and Interference Treatments that interfere with protein synthesis at the cellular level will soon be debated in medical policy committee meetings.
Chemistry World January 20, 2011 Hayley Birch	Programmable RNA promising for bio-compatible therapies Programmable nanostructures based on ribonucleic acid could be used as vessels for shipping therapeutic molecules into cells, according to US scientists.
Bio-IT World April 15, 2003 Malorye Branca	Beyond the Blueprint How will the wealth of data emanating from the human genome and allied technologies impact research on health and disease?
Chemistry World March 15, 2007 Henry Nicholls	The Mother of All Enzymes Scientists have uncovered the three-dimensional structure of what might be biology's first enzyme. This sheds light on the chemistry at a key moment in the origin of life, they argue.
Reactive Reports October 2006 David Bradley	RNA Chemistry Zips Up Nobel Prize If Watson and Crick unlocked the mystery of DNA's structure, then Stanford University's Roger Kornberg and his team unzipped the secret of how the cell converts DNA into the RNA needed to make proteins.
HHMI Bulletin February 2011 Michele Solis	Right Before Your Eyes Coupling protein sequence to function, thousands of variants at a time.
HHMI Bulletin May 2010 Robert Tjian	Biomolecular Crowdsourcing A generation of web-savvy entrepreneurs has found a relatively cheap and effective approach to solving complex problems and soliciting ideas: toss out a challenge into a vibrant digital community and watch what happens.
HHMI Bulletin February 2011 Sarah C.P. Williams	Skin Sense An early question about aging skin led to answers on how cells code for their location.
Bio-IT World December 15, 2004 William Marshall	Applications of RNAi RNA interference is a highly coordinated gene regulatory mechanism that appears to be highly conserved across all metazoans studied thus far.
Reactive Reports Apr/May 2005 David Bradley	At Last, the Structure of DNA Researchers have made a significant advance in our understanding of life's main molecule, using X-ray crystallography to determine the three-dimensional structures of nearly all the possible sequences of a macromolecule.
Chemistry World April 20, 2009 James Urquhart	New method reveals small molecule-RNA conjugates US scientists using novel chemical screening methods have discovered a new class of small molecules connected to RNA, suggesting that cellular RNA may be more chemically diverse than previously thought.
Bio-IT World December 15, 2004 Nancy Weil	Running Interference The revolution in RNA interference has galvanized basic research. Now, some biopharmas are pushing the technology from the laboratory to the clinic.
Chemistry World November 27, 2007 James Mitchell Crow	A Flare for Gene Silencing US scientists have developed nanoparticle probes coated with DNA that release fluorescent 'flares' when they silence genes inside cells.
Chemistry World January 11, 2008 John Bonner	DNA Nanoparticles Detect Gene Expression US scientists have made nanoparticles from DNA that they say could be used to identify the genes being expressed in a single cell.
Chemistry World January 31, 2008 John Bonner	RNAi Scores Victory Against Crohn's Disease in Mice Thousands of people suffering from the debilitating gut condition Crohn's disease could experience relief from their symptoms through a technique that blocks production of a key protein in the inflammation process.
Chemistry World August 7, 2008 Simon Hadlington	RNA stops HIV in its tracks Scientists have successfully used a biochemical Trojan horse to smuggle killer sequences of RNA into immune cells to mug invading HIV, stopping infection in its tracks
Chemistry World June 29, 2007 Lionel Milgrom	Engineered Enzyme to Excise Aids Current HIV/AIDS treatments suppress the virus's life-cycle without curing the disease. Now, German researchers are pioneering a strategy that might help to eradicate the virus altogether.
Bio-IT World December 15, 2004 David A. Bumcrot	Identifying RNAi Drug Candidates Breakthroughs in understanding RNA's extensive role in essential cellular processes have opened up the potential for a whole new class of drugs based on RNAi.
Chemistry World August 29, 2007 Ananyo Bhattacharya	'Lost' Folate Enzyme Found After 30 Years US researchers have revealed the identity of an enzyme used by bacteria to make the essential B vitamin folate, 30 years after it was first isolated.
Chemistry World October 4, 2006 Bea Perks	Good Year for RNA Roger Kornberg, professor of structural biology at Stanford University, has been awarded the 2006 Nobel prize in chemistry for his work on the molecular basis of transcription.
Chemistry World September 23, 2009 Simon Hadlington	Direct route to RNA sequences Scientists in the US appear to have cracked a major problem in molecular biology: how to sequence single molecules of RNA directly.
Chemistry World April 28, 2008 Victoria Gill	Gene silencing gets fat A team of researchers in the US has developed fat-like nanoparticles that can carry fragments of RNA into cells, bring treatments based on gene silencing a step closer.
Chemistry World March 21, 2010 Simon Hadlington	Nanoparticles successfully deliver RNA interference in cancer patients The system aims to exploit the phenomenon of RNA interference, where short sequences of double-stranded RNA, called small interfering RNA or siRNA, can trigger the disruption of the manufacture of certain proteins in a cell.
Chemistry World February 12, 2014 Manisha Lalloo	Synthetic strategy targets 'undruggable' small RNAs Chemists in the US have found a way to predict small molecules that can target short pieces of RNA involved in some diseases, such as cancer.
The Motley Fool September 28, 2007 Brian Orelli	RNAi Doesn't Kill Mice After All From Merck, to AstraZeneca, to Novartis, big pharma continues to pump hundreds of millions of dollars into unproven RNAi technology. Investors, take note.
Wired September 25, 2007	Three Smart Things You Should Know About Bacteria The benefits of bacteria.
Chemistry World August 28, 2007 Tom Westgate	Repairing DNA Could Let Frozen Bacteria Survive for Millennia An international team of scientists believe they have strong evidence that bacteria trapped in permafrost are able to survive for hundreds of thousands of years by repairing their DNA.
Technology Research News June 16, 2004	Genes Automate DNA Machines Researchers have taken a step toward automating nanomachines with a method that allows instructions for a DNA-based machine to be contained in a gene, or another stretch of DNA.
Chemistry World February 1, 2008 Lewis Brindley	Genetic Code Read Directly From RNA Scientists have directly read the genetic code from a single strand of RNA for the first time, using a combination of powerful microscopes and laser spectroscopy techniques.
Fast Company May 2009 Elizabeth Svoboda	Biotechs Wage War on Superbugs With antibiotic resistance on the rise, three biotechs are developing new ways to wage war on superbugs.
Chemistry World January 28, 2011 David Barden	Chips make short work of RNA synthesis Chinese scientists have developed a much easier way to make the short strands of RNA that are an essential tool in understanding what genes do.
Scientific American January 2006 Charles Q. Choi	Un-Killing the Messenger Processing bodies do more than serve as RNA trash bins in cells. Research now suggests that these P-bodies are less like junkyards and more like office centers, where messages are amassed, silenced and reactivated.
Wired October 2003 Richard Martin	How Ravenous Soviet Viruses Will Save the World They're called phages. And they eat drug-resistant bacteria for breakfast.
Chemistry World June 21, 2007 Simon Hadlington	Boron is Key to Antifungal Agent Researchers have shown that the presence of a boron atom is key to an antifungal agent being developed to treat infections of fingernails and toenails.
Scientific American March 2009 W. Wayt Gibbs	Evolution in a Bottle: Synthetic Life Oozes Closer to Reality Self-replicating RNAs advance science another step toward artificial life
Chemistry World January 25, 2010 Hayley Birch	Stabilising RNAs enhances gene silencing in tumours South Korean scientists have found a way to stabilise therapeutic RNA molecules, using chemical modifications, so that they can be more smoothly trafficked into cells.