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Chemistry World November 29, 2010 James Mitchell Crow |
DNA readers ratchet closer Rapid, cheap DNA sequencing has just edged a step closer, thanks to a new technique to control the motion of single DNA strands as they pass through a protein nanopore 'reader'. |
Chemistry World February 22, 2009 Phillip Broadwith |
Reading DNA Base by Base A technique to electrically detect individual DNA bases cut from a single strand of DNA has been developed by researchers in the UK. |
HHMI Bulletin February 2012 Sarah C. P. Williams |
Force Factor In the context of cells, forces are required to move molecules. Quantifying these forces gives scientists a way to compare and contrast different molecular motors. |
IEEE Spectrum June 2009 Prachi Patel |
Advance in Nanopore Gene Sequencing Magnets help in the quest for the $1000 genome |
Technology Research News March 24, 2004 |
DNA has nano building in hand Researchers from Ludwig Maximilians University in Germany have built a simple molecular machine from DNA that can bind to and release single molecules of a specific type of protein. |
Technology Research News April 23, 2003 Kimberly Patch |
DNA motor keeps cranking Researchers have been making DNA perform all sorts of shape-changing tricks in recent years, but the need to add pieces of DNA at every step has made it a bit of a stretch to call these molecules motors. A method that keeps the process humming changes things. |
Chemistry World April 3, 2008 Lewis Brindley |
DNA Read in a Trice The prospect of treatments that are tailored to fit an individual's genetic makeup is a step closer thanks to technology unveiled by US scientists. |
Chemistry World April 25, 2006 Jon Evans |
DNA Sequencing Reaches the Space Age The smallest ever DNA sequencer, only 10cm in diameter, comprises a complex network of microscopic pumps, valves, heaters and electrophoresis channels, many of which were initially developed for use in a device to detect life on Mars. |
Chemistry World October 31, 2008 Manisha Lalloo |
DNA-rewinding protein discovered US scientists have found an enzyme that rewinds sections of DNA whose strands have mistakenly come apart. |
Chemistry World February 3, 2013 Andy Extance |
Enzyme draws nanopore protein sequencing nearer US scientists at the University of California, Santa Cruz, have made a key step towards nanopore protein sequencing, thanks to an 'unfoldase' enzyme. Mark Akeson's team exploited this enzyme to unravel proteins and pull them through nanopores. |
HHMI Bulletin Feb 2011 |
DNA Curtains How proteins behave in such a crash test gives scientists data about their structural integrity, how they attach to DNA, and how they behave in a cell. |
Technology Research News September 24, 2003 |
Glow shows individual DNA Researchers have made a type of artificial DNA of that glows when it combines with a specific sequence of natural DNA. In principle, the method could be used to develop DNA chips that directly sense individual DNA molecules. |
Chemistry World September 23, 2009 Simon Hadlington |
Direct route to RNA sequences Scientists in the US appear to have cracked a major problem in molecular biology: how to sequence single molecules of RNA directly. |
Chemistry World September 17, 2012 Ian Le Guillou |
Raising the curtain on single-stranded DNA Scientists have created microfluidic devices containing single-stranded DNA 'curtains' for the first time, allowing scientists to study its interactions with proteins in real time. |
Chemistry World November 16, 2006 Simon Hadlington |
Gene-Reading Enzyme Catapulted by Scrunch Power Two teams of researchers have solved a conundrum that has baffled molecular biologists for 20 years -- how the enzyme responsible for `reading' genes can release itself from the portion of DNA to which it initially binds extremely tightly. |
Chemistry World October 19, 2009 Simon Hadlington |
DNA stretching mystery solved A detailed understanding of the elastic properties of DNA can give scientists key insights into interactions of DNA and the proteins that carry out these manipulations. |
Chemistry World March 1, 2011 Catherine Bacon |
Unravelling chromosomes Danish scientists have used a micro device to isolate centimetre-long portions of human DNA to help study the genetic make-up of diseased cells. |
Chemistry World February 27, 2006 Michael Gross |
A DNA Switch for RNA Folding Researchers have equipped a large RNA domain with a DNA switch, which they say can fold or unfold the RNA molecule at will. |
Technology Research News March 12, 2003 |
RNA forms nanomotor Researchers from Purdue University have constructed a tiny motor from DNA and RNA molecules. The device, fueled by ATP, which powers our own movements, could eventually power nanomachines. |
Technology Research News August 22, 2005 |
DNA Technologies The versatile DNA molecule has proven to be a powerful technological building block. Researchers have developed ways of combining DNA molecules that allow them to carry out computations in test tubes and create two-dimensional patterns and three-dimensional structures at the nanoscale. |
Chemistry World February 21, 2012 Phillip Broadwith |
Nanopore sequencing bags its first genome Oxford Nanopore has presented the first complete genome to be sequenced using a nanopore. |
Chemistry World January 11, 2008 John Bonner |
DNA Nanoparticles Detect Gene Expression US scientists have made nanoparticles from DNA that they say could be used to identify the genes being expressed in a single cell. |
Chemistry World August 2007 Philip Ball |
Opinion: The Crucible The twist on DNA |
Technology Research News June 15, 2005 Kimberly Patch |
DNA Machine Links Molecules Researchers have fashioned a nanomechanical device from DNA that can be programmed to align a series of molecules and fuse them together. The technique could potentially be used to put together designer polymers, encrypt information, and carry out computations. |
Chemistry World January 2012 |
DNA motors on With the relentless rise of DNA nanotechnology's popularity, Emma Davies explores the role chemistry has played in its success |
Chemistry World November 7, 2013 Simon Hadlington |
Rocket-propelled read-out for new DNA chip US researchers have invented a lab-on-a-chip that can measure how much of a specific strand of DNA is in a sample using a 'rocket-propelled' thread of ink that can be read by eye. |
Reactive Reports Apr/May 2005 David Bradley |
At Last, the Structure of DNA Researchers have made a significant advance in our understanding of life's main molecule, using X-ray crystallography to determine the three-dimensional structures of nearly all the possible sequences of a macromolecule. |
Chemistry World October 25, 2011 Jon Evans |
Carbon nanotubes detect DNA 'flipping out' US chemists have developed a way to detect the chemical modification of a single strand of DNA, by hooking it up to a pair of carbon nanotubes. |
Chemistry World May 15, 2006 Jon Evans |
Selective DNA Crystals A molecular biologist has developed a molecular sieve using a DNA crystal with nanoscale channels. |
Chemistry World November 16, 2011 Simon Hadlington |
Unlocking the secrets of DNA's stiffness Computational chemists believe they have solved one of the puzzles about the stiffness of DNA: how much of the molecule's rigidity is due to electrostatic forces and how much to its physical structure. |
Chemistry World February 28, 2010 Jon Cartwright |
Reactions on DNA origami watched with AFM Chemists in Denmark have for the first time imaged chemical reactions on a DNA origami scaffold so that they can precisely attach single molecules, involving atomic force microscopy. |
Technology Research News June 16, 2004 |
Genes Automate DNA Machines Researchers have taken a step toward automating nanomachines with a method that allows instructions for a DNA-based machine to be contained in a gene, or another stretch of DNA. |
Technology Research News November 3, 2004 Smalley & Patch |
DNA Machines Take a Walk Researchers working to form nanoscale machines and materials are increasingly tapping into nature's building blocks. |
Chemistry World October 19, 2015 Matthew Gunther |
The house that DNA built The 2015 chemistry Nobel prize was awarded to Tomas Lindahl, Paul Modrich and Aziz Sancar for DNA repair. |
Chemistry World February 1, 2008 Lewis Brindley |
Genetic Code Read Directly From RNA Scientists have directly read the genetic code from a single strand of RNA for the first time, using a combination of powerful microscopes and laser spectroscopy techniques. |
Chemistry World April 18, 2010 Simon Hadlington |
First DNA rotaxane Rotaxanes are dumbbell-shaped molecules encircled by a molecular hoop that can move unhindered along the axle, trapped by the bulky stoppers at either end. These could be useful components in molecular machines. |
IEEE Spectrum March 2011 Lucks & Arkin |
Synthetic Biology's Hunt for the Genetic Transistor How genetic circuits will unlock the true potential of bioengineering |
Chemistry World May 7, 2014 Emma Stoye |
Bacterium survives unnatural DNA transplant The first organism that can grow and replicate with an unnatural base pair in its DNA -- giving the cell six nucleotides instead of the usual four -- has been created by scientists in the US. |
Chemistry World March 8, 2010 Lewis Brindley |
Molecular midwives helped birth of DNA 'Molecular midwives' - are compounds that played a crucial role in combining small nucleotide fragments into the first genetic polymeric material. |
Chemistry World April 19, 2012 Andy Extance |
Polymers perform non-DNA evolution Scientists have found that six polymer alternatives to DNA can pass on genetic information, and have evolved one type to specifically bind target molecules. |
Technology Research News August 25, 2004 |
DNA Copier Uses Little Power Today's laboratory DNA detectors require a lot of energy. Researchers have devised a method that copies the way DNA is replicated biologically in order to avoid the energy-intensive heating and cooling process. |
Chemistry World May 16, 2007 Tom Westgate |
DNA Photography It is a technology that is fast disappearing in the digital age. But black and white photography is more than an archaic art-form to a team of German chemists who have used it as the basis for a simple method of detecting labeled DNA molecules at attomole levels. |
Chemistry World October 17, 2011 Hayley Birch |
Quickly sorting cells using DNA A new magnetic cell sorting technique uses principles borrowed from DNA nanodevices. The approach could help scientists rapidly separate different types of cells from complex mixtures. |
Technology Research News November 3, 2004 Kimberly Patch |
DNA in nanotubes sorts molecules Researchers have made a synthetic membrane that recognizes certain biochemical molecules and allows them to pass through. The method could be used to make biological sensors like those needed for genetics research, and to sort biological molecules, |
Chemistry World February 18, 2008 John Bonner |
Flicking the Acetyl Switch A strain of Escherichia coli that can produce proteins containing an acetylated version of the amino acid lysine could help to reveal how acetylation changes the function of hundreds of proteins inside cells. |
Bio-IT World September 2005 Kevin Davies |
Fantastic 454: DNA Sequencing Pyrotechnics In an exciting advance for DNA sequencing technology, a research team at 454 Life Sciences Corp. has essentially sequenced and assembled a bacterial genome sequence based on a mere 4-hour run on the company's proprietary instrument. |
Technology Research News May 5, 2004 Kimberly Patch |
DNA Bot Targets Cancer Researchers from Israel have constructed a molecular-size computer that is programmed to find signs of cancer cells, and when they are present, dispense DNA molecules designed to eradicate those cells. |
Technology Research News February 11, 2004 |
Scientists brew tree-shaped DNA Researchers from Cornell University have synthesized a new type of DNA that can be used as a nanotechnology building block. |
Reactive Reports Issue 54 David Bradley |
Hula-Hoop DNA Amplification Periodic nanostructures made of gold nanoparticles and long DNA strands with repeated sequences have been prepared by using a technique known as "rolling circle amplification" or the "hula-hoop" technique. |
Chemistry World January 20, 2011 James Urquhart |
SNPs on display DNA origami and atomic force microscopy have been combined to reliably detect and image single nucleotide polymorphisms, the most common form of genetic variation in the human genome. |