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Reactive Reports Issue 52 David Bradley |
Interview with Gary Martin With more than 35 years experience in NMR spectroscopy, Gary Martin reveals some of the insights he has gained in this field. |
Chemistry World January 9, 2014 |
Spinning into focus NMR is used by big industry, and scientists in pharmaceutical companies, for example, have appreciated the benefits of NMR spectroscopy for years. It reveals the structure of molecules in a sample, providing more information than some other analytical techniques. |
Chemistry World August 30, 2006 Tom Westgate |
Lasers Shed Light on Magnetic Resonance A new way of measuring nuclear magnetic resonance (NMR) in liquid samples could have implications across spectroscopy and imaging, report researchers. |
Chemistry World June 14, 2011 |
A New Spin on Protein NMR A new technique will allow researchers to study protein structure in greater detail using NMR. |
Chemistry World October 16, 2006 Michael Gross |
Brief Encounter Observing fleeting interactions between molecules in solution requires extremely sophisticated methods. NMR spectroscopists have now developed tools that let them watch the transient encounter between two proteins before a well-defined complex is formed. |
Bio-IT World July 2005 Robert M. Frederickson |
Amassing Mass Spectrometry Tools Mass spectrometry is a key tool in the effort to identify protein biomarkers of human disease. Manufacturers have met major challenges in adapting this technology to protein discovery, both qualitatively and quantitatively. |
Chemistry World October 26, 2007 Richard Van Noorden |
Proton NMR Spots Shape-Shifting Tablets UK scientists have extended the bounds of solid-state NMR to quickly solve a problem plaguing the pharmaceutical industry: how to spot unwanted crystal packing forms in a drug tablet. |
Chemistry World March 2007 Dylan Stiles |
Opinion: Bench Monkey For structural analysis of small molecules, NMR spectroscopy can't be beat. |
Chemistry World November 21, 2014 Simon Hadlington |
Magnetic resonance taken to the limit Researchers in the US have taken magnetic resonance imaging to its extreme by developing a technique to detect the spin of a single nucleus. |
Chemistry World June 24, 2011 Yuandi Li |
An NMR machine in a fume hood Scientists in Germany have demonstrated a portable nuclear magnetic resonance spectrometer that's small enough to be placed in a fume cupboard to monitor the progress of a reaction in situ. |
Chemistry World January 30, 2013 Philip Robinson |
NMR with a light touch Interactions between NMR-active nuclei in a sample and laser light could lead to a new, simpler form of NMR. |
Chemistry World May 2006 |
New on the Market Spectrometer for field use... 3D nano movies... NMR cryoprobes... High optical throughput... Detecting nuclear threats... Sensing hazardous gases... LC/MS with ultra performance... etc. |
Chemistry World May 14, 2010 Phillip Broadwith |
Powerful pocket sized NMR magnets Arrangements of chunks of permanent magnetic material that can be tweaked to give strong, uniform fields could open the door to more sensitive and higher resolution portable nuclear magnetic resonance spectrometers, say researchers in Germany. |
Chemistry World January 14, 2009 Hayley Birch |
MRI at the nanoscale US scientists have demonstrated the remarkable power of magnetic resonance imaging (MRI) by adapting it to create 3D nanoscale pictures of a tobacco mosaic virus. |
HHMI Bulletin Spring 2013 Nicole Kresge |
A Structural Toolbox Natalie Strynadka wants to design a better antibiotic. Her strategy: learn about the molecules bacteria use to invade cells. Her tool: structural biology. |
Chemistry World October 8, 2007 James Mitchell Crow |
MRI Sensitivity Boosted by 10000 Times A technique that significantly boosts the sensitivity of magnetic resonance imaging is on the verge of clinical trials which, if successful, could allow doctors to assess the effects of cancer drugs on a tumor within hours. |
Chemistry World June 12, 2013 Kirsty Muirhead |
An end to chasing molecules that were never there? Ariel Sarotti from the Rosario National University, Argentina, has developed a new, computationally inexpensive method combining calculated and experimental 13C NMR data to flag up incorrect structures. |
Chemistry World November 23, 2006 Simon Hadlington |
Unfolding Peptide Watched in Real Time Researchers have observed a peptide molecule changing shape in real time. The ultrafast process was monitored using a technique called transient two-dimensional infrared spectroscopy. |
Chemistry World August 1, 2010 Mike Brown |
Snapshots of mystery molecular structures Researchers have used atomic force microscopy to produce clear molecular images that can help determine the correct atomic structure of unknown organic molecules. |
Chemistry World November 4, 2013 Jennifer Newton |
Moving the goalposts for MRI A new class of MRI (magnetic resonance imaging) contrast agents developed by scientists in the UK is promising to deliver clearer images in less time. |
Chemistry World October 1, 2014 Philip Ball |
Probing molecules atom by atom A new technique that can 'see' individual spins of electrons and nuclei in single molecules could enable nuclear magnetic resonance spectroscopy atom by atom. |
Bio-IT World July 2005 |
New Products HyperSense Makes Sense... BINDing Interactions for Drug Discovery Applications... Images of a GeneGnome... Low-Volume Cell: High Conversion... Arrayjet Takes Off with Microarray Spotter... |
Chemistry World March 6, 2013 Michal Leskes |
Solid state NMR: basic principles & practice This book by Apperley et al., first considers different types of solids and their properties, followed by a detailed survey of the main NMR interactions and phenomena that govern the spectra. |
Chemistry World November 7, 2012 Ian Le Guillou |
Coral animal chemical structures solved A combination of atomic force microscopy and computational techniques have been used to solve the unusual structures of two natural products from the Arctic coral-like animal, Thuiaria breitfussi. |
Chemistry World January 20, 2011 Jon Cartwright |
Chemists separate water isomers Chemists in Israel claim to have separated water into its two spin isomers and suggest the outcome could deliver highly sensitive nuclear magnetic resonance experiments. |
Chemistry World May 17, 2012 David Bradley |
Plutonium in a Spin Spectroscopists have finally pinned down the nuclear magnetic resonance spectrum of plutonium-239. The finding might point the way to improved approaches to the long-term storage of nuclear waste. |
Chemistry World October 23, 2014 Andy Extance |
Agilent to exit NMR US-headquartered instrument maker Agilent Technology has stopped taking orders for new nuclear magnetic resonance spectrometers, leaving many within the chemistry community with tough choices. |
Chemistry World March 15, 2010 Matt Wilkinson |
An agile future Nick Roelofs, president of Agilent Technology's life sciences group, discusses how the company is planning to ride the waves of the economic recovery. |
Chemistry World September 25, 2009 Simon Hadlington |
New MRI protein probe Researchers in Japan have invented a new way to detect the presence of proteins in cells and tissues by magnetic resonance imaging. |
HHMI Bulletin Winter 2013 Nicole Kresge |
A Structural Revolution Over the years, scientists and artists have used an assortment of techniques to showcase molecular structure. |
Chemistry World May 19, 2014 James Urquhart |
'Heavy' mouse helps out tissue engineers UK researchers have developed a tissue molecular mapping method that could help make lab-grown tissue much more like the real thing. |
Chemistry World February 27, 2009 Hayley Birch |
More data from mixtures via NMR Finnish scientists have developed a new technique for separating out the NMR spectra of compounds in a mixture. |
Chemistry World October 31, 2014 |
X marks the structure From single crystals to powders and even proteins, there's a diffractometer for every structure. |
Chemistry World July 13, 2010 Mike Brown |
NMR: Nobel work if you can get it There are plenty of practicing chemists who are grateful for Richard Ernst's work to develop what the Nobel committee described as 'perhaps the most important instrumental measuring technique within chemistry.' |
Chemistry World July 12, 2011 Kate McAlpine |
Bit Part for Diethylfluoromalonate in Reaction Model A quantum simulation has successfully described the progression of a chemical reaction for the first time. |
Chemistry World March 21, 2013 Neil Withers |
Harry Kroto: From light years to nanometers -- and back My emphasis in the Pittcon plenary lecture is that the discovery of C 60 started off from an interest in massive clouds of gas in interstellar space. You go from these huge objects into the nanoscale world and back again out into space. |
Bio-IT World July 14, 2004 Karen Hopkin |
'Omics: The NextGeneration Researchers in industry and academia are cataloging collections of biochemical compounds (metabolomics) to determine how they respond when organisms are challenged by drugs, disease, or stress (metabonomics). |
Chemistry World November 25, 2014 Hugh Cowley |
Benchtop NMR gives feedback in flow The platform performs algorithm driven organic synthesis using real-time feedback from in-line flow NMR spectroscopy |
Popular Mechanics March 2003 Paul Eisenstein |
World's Most Powerful Magnet The "magnetar," or magnetic neutron star known as Soft Gamma Repeater 1806-20, is the most powerful known magnetic object in the universe. While it's unlikely anything man-made will ever come close to the power of a magnetar, it's not for lack of trying. |
Chemistry World July 26, 2012 Cecilia Fenech |
Understanding 2D NMR Organic structure determination using 2-D NMR spectroscopy: a problem-based approach by Jeffrey Simpson is a balanced text covering both theoretical and practical aspects of NMR spectroscopy. |
Chemistry World February 2, 2012 Philip Robinson |
Ultrafast NMR shows the way Chemists have created an ultrafast NMR technique that can 'watch' how chemical reactions occur in real time. They've used the technique to follow the formation of pyrimidines from carbonyls and even identified new intermediates never before thought to be part of the reaction. |
Reactive Reports Issue 43 |
Star Picks Science website suggestions: Switchback Fair... Worlwide Molecular Matrix... Musical NMR... etc. |
Chemistry World May 24, 2006 |
Detecting Brain Damage Before it Happens An NMR technique under development could help the victims of stroke by detecting brain damage early enough to provide treatment. |
Chemistry World May 30, 2014 Phillip Broadwith |
How good do you want it? In a chemical manufacturing environment, the most important questions for process chemists are qualitative: how shall we make this molecule? How can we do it safely? |
Chemistry World December 2, 2014 Helen Carmichael |
Eleventh hour reprieve for world-class Canadian NMR facility Canadian scientists are celebrating a victory in a bleak landscape for research funding, as a world-class nuclear magnetic resonance facility received a last minute reprieve from closure. |
Chemistry World February 24, 2014 Derek Lowe |
Tools of the trade Organic synthesis has always depended on instrumental analysis, even when the instruments were a thermometer for distillations and a melting point stage for crystals. |
Chemistry World July 31, 2009 Matt Wilkinson |
Agilent swoops on Varian Agilent is buying rival analytical instrument maker Varian for $1.5 billion ( 900 million) - a move that will increase its market share in the bioanalysis arena and mark its entry into the nuclear magnetic resonance (NMR) market. |
Chemistry World July 2007 Dylan Stiles |
Opinion: Bench Monkey Synthesizing molecules that force atoms into bizarre contortionist acts is the only way to learn. |
Chemistry World November 13, 2012 Phillip Broadwith |
Calculations correct natural product structure US chemists have used NMR prediction calculations to correct the structure of a complex natural product, aquatolide. The work emphasises the power of this burgeoning technique to challenge and inform experimental structure determination. |
Chemistry World June 25, 2013 Michael Gross |
A foaming protein from the horse's mouth Researchers in the UK have solved the structure of this protein, yielding tantalizing hints to a novel kind of surface activity and to evolutionary connections to other examples. |