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Chemistry World October 12, 2007 James Mitchell Crow |
Flow Reactors Enter the Rapids Continuous flow chemistry's promise to shake up synthesis gathered momentum this month, with the first Uniqsis Flow Chemistry Symposium. |
Chemistry World March 2011 |
Microwave chemistry - green or not? Microwave-assisted chemistry might not deserve its environmentally friendly reputation, argues Jonathan Moseley |
Chemistry World November 25, 2014 James Urquhart |
Nanomolar chemistry enables 1500 experiments in a single day Chemists have conducted over 1500 chemistry experiments in under a day thanks to a miniaturized, high throughput automation platform they developed for identifying how synthetic molecules react under various conditions. |
Chemistry World October 22, 2013 Marie Cote |
Oliver Kappe: Freedom to explore Oliver Kappe is professor of chemistry at the University of Graz in Austria. Research in the Kappe group focuses on enabling technologies for synthesis, including microwave and continuous flow methods. |
Chemistry World February 20, 2013 Amy Middleton-Gear |
Ohmic heating for efficient green synthesis Portuguese scientists have developed a new ohmic-heating reactor for organic syntheses on water, or chemistry using an aqueous suspension of the reactants. |
Chemistry World September 19, 2008 Lewis Brindley |
Chemical conversion made twice as green A combination of two green processes - supercritical fluids and photochemistry - could have a bright future for performing environmentally friendly reactions on an industrial scale |
Chemistry World March 8, 2009 Nina Notman |
Polymer Crossroads Act as Tiny Reactors Scientists in the US have taken inspiration from a Dutch painter to create ultrasmall chemical reactors at the junctions of overlapping polymer nanofibres |
Chemistry World December 5, 2012 Phillip Broadwith |
Chemical reactions in hot water Chinese and Japanese chemists have highlighted hot water's ability to promote unexpected reactions without any other reagents or catalysts. The work should expand our understanding of how to harness the physicochemical properties of water to potentially replace more complex reagents and catalysts. |
Chemistry World November 2007 Derek Lowe |
Column: In the Pipeline Chemists are finally going with the flow. |
Chemistry World April 30, 2013 Andy Extance |
Microreactors tame osmium tetroxide Researchers in South Korea and India have made microfluidic reactors that safely harness the synthetically powerful but noxious catalyst osmium tetroxide. |
Chemistry World June 24, 2010 Phillip Broadwith |
Aryl rings get a fluorine fix A mild and effective method for coupling trifluoromethyl groups on to aryl rings has been developed by US chemists. |
Chemistry World October 23, 2013 Emma Eley |
Synthesis by sunlight Sustainable oxidation reactions can be performed with inexpensive and readily available photovoltaic cells |
Chemistry World November 1, 2012 Laura Howes |
Shining new light on the Ullmann reaction Ullmann C -- N coupling -- a copper mediated carbon -- nitrogen coupling reaction used to create arylamines -- is one of the most widely used reactions in the pharmaceutical industry. |
Chemistry World February 2, 2012 Elinor Richards |
Magical microwaves Microwaves have been used to promote organic reactions since the 1980s and they can lead to higher yields and shorter reaction times than conventional heating, but why? |
Chemistry World October 2007 Derek Lowe |
In the Pipeline One of the biggest areas of chemical research these days is in catalytic processes. It's one of the places we can really improve our processes, especially when you count the waste stream (as you should) as part of the total energy bill. |
Chemistry World August 16, 2009 Tom Bond |
Catalyst free carbon-carbon bond formation The method offers an environmentally friendly way to form one of the most important bonds in organic synthesis. |
Chemistry World August 26, 2010 Simon Hadlington |
A self-optimising microreactor system Chemists in the US have developed a microreactor system which automatically calculates the optimal conditions for the chemical reaction it is undertaking. |
Chemistry World April 18, 2012 Elinor Richards |
Homogeneous Catalyst Recovery Made Easier Scientists have now found a way to recover homogeneous catalysts at the end of a chemical reaction that doesn't suffer from the slow reaction rates that affect current catalyst recovery systems. |
Chemistry World October 23, 2013 Manisha Lalloo |
NMR thermometer takes reactor's temperature Scientists in the US have used NMR to create temperature maps of reactions taking place inside catalytic reactors. Their technique opens the door to an easy, non-invasive way to discover hot and cold 'spots' inside reactors. |
Chemistry World May 26, 2015 |
Catching the runaways I think each cohort of industrial chemists has a runaway industrial reaction that defines their generation. |
Chemistry World September 28, 2015 Karl Collins |
A witches' brew for trifluoromethylation Trifluoromethylating phenols is one example of a reaction that would be incredibly useful when attempting to tune the chemical and biological properties of molecules for pharmaceutical and agrochemical research. |
Chemistry World October 2, 2009 Phillip Broadwith |
Microwave effect ruled out Microwave reactions in silicon carbide vials - which are heated by microwaves but shield the contents from radiation - have confirmed that most of the benefits seen in microwave-assisted chemistry are purely due to heating |
Chemistry World August 12, 2015 Matthew Gunther |
Chemists hold a candle to reagent preservation Scientists in the US now have a solution to end the build-up of chemical waste with a wax capsule that can protect reagents from the atmosphere. |
Chemistry World September 2011 Paul Docherty |
Column: Totally Synthetic Corey Stephenson of Boston University is an expert a type of reaction called photochemical reduction-oxidation. He has charmed photons into performing many chemical tricks, but one is a photoredox dehalogenation using blue light and a ruthenium bipyridyl catalyst. |
Chemistry World January 17, 2014 Katia Moskvitch |
Life may have begun in a tiny water droplet Chemical reactions run much faster and more efficiently when they take place in tiny droplets rather than in freestanding water -- such as a puddle or a lake, say researchers. |
Chemistry World August 22, 2014 Derek Lowe |
Death of a reagent Anyone who's been practicing organic chemistry for a while can think back to reactions and reagents that were once in far wider use than they are today. |
Chemistry World October 15, 2015 Aurora Walshe |
Carbon dioxide sees the light Collaborators in Spain and Germany have built a microreactor that uses visible light to drive a reaction that turns carbon dioxide into carbon monoxide -- an important chemical building block. |
Chemistry World January 25, 2013 Derek Lowe |
Name reactions: how does the label stick? Some of these names go back to the 19th century, and many more of them come from the first decades of the 20th. Once in a while, I wonder if the tradition is dying out. Are we still naming chemical reactions after their discoverers? |
Chemistry World March 24, 2015 Karl Collins |
Back to basics for silylation While silicon is probably most familiar in organic synthesis as part of protecting groups, its utility extends much further. |
Chemistry World November 2010 |
Carbon Couplers Take the Prize Three giants of organic chemistry, who pioneered palladium-catalysed cross coupling reactions, have shared this year's Nobel prize. |
Chemistry World January 29, 2014 Elisabeth Ratcliffe |
Flow system overcomes reagent incompatibility issues Synthesizing cyclic carbonates could become easier and more efficient thanks to a sequential flow system developed by scientists in the US. |
Chemistry World March 21, 2007 Richard Van Noorden |
Forcing a Reaction US chemists have forced molecules to react by ripping their bonds apart with ultrasound. The scientists carefully stretched one targeted bond until it snapped, guiding the molecule's subsequent reaction into pathways forbidden by conventional chemistry. |
Chemistry World September 26, 2012 Derek Lowe |
Under pressure Someone interviewing for a synthetic chemistry position had better know his or her organic chemistry. It's fair to ask questions that will make sure of that. But does a candidate need to know the curly-arrow details of reactions that they'll never run? |
Chemistry World May 8, 2012 Phillip Broadwith |
Keep stirring that Suzuki The shape of your reaction vessel can influence the behavior of organotrifluoroborate compounds in Suzuki cross-coupling reactions, say chemists in the UK. |
Chemistry World January 25, 2008 Simon Hadlington |
Catalysis Probed with MRI Scientists have developed a way of peering into a microreactor to watch gases react on a solid catalyst. |
Chemistry World October 15, 2012 Melissae Fellet |
Synthesis by mass spectrometry Chemists have used mass spectrometry, commonly used to analyze molecules, to synthesize them on the microscale. |
Chemistry World August 28, 2014 |
Trekking across chemical frontiers Thinking about getting molecules to where they need to go is a new concept for the novice process chemist, but is familiar to chemical engineers as mass transfer. |
Chemistry World July 3, 2015 Andy Extance |
Copper catalysis overcomes double bond trouble Some carbon-carbon double bonds seem too unreactive for synthetic use -- but that's just how chemists in the US are now exploiting them. |
Chemistry World July 14, 2009 Phillip Broadwith |
Multicomponent reactions step up a gear Dutch chemists have taken multicomponent reactions to the next level, combining a total of eight different starting materials in a single flask, bringing together three different multicomponent reactions and making nine new bonds in a single step. |
Chemistry World October 2009 |
Column: In the pipeline Derek Lowe discusses the problem of leaning too heavily on favorite reactions |
Chemistry World July 22, 2013 Anthony King |
Microwave quarrel heats up A brouhaha over microwave heating in organic reactions has escalated after the two research groups involved penned barbed correspondences aimed at each other's approaches in Angewandte Chemie. |
Chemistry World August 6, 2014 Simon Hadlington |
3D printed reactionware hots up UK researchers have shown that it is possible to carry out a range of hydrothermal chemical syntheses in sealed reactors made from 3D printed polypropylene. |
Chemistry World March 20, 2008 James Mitchell Crow |
Surfactants Help Reactions Work in Water Scientists have discovered a surfactant that allows the catalytic organic reactions commonly used to assemble organic structures such as drug molecules to be run in water. |
Chemistry World May 22, 2015 James Urquhart |
Complex amines made easy (and cheap) Phil Baran's lab at the Scripps Research Institute, La Jolla, has come up with a protocol that repurposes two readily available and inexpensive feedstock building blocks; olefins and nitroarenes, via iron-catalysed cross-coupling. |
Chemistry World July 31, 2014 Helen Bache |
Tracking complex reactions in space and time Scientists in Taiwan have put together a system that uses a computer screen and digital camera to obtain spatial, temporal and spectral information on reaction samples, for a low cost. |
Reactive Reports Issue 67 David Bradley |
Multichannel Microchemical Factory The microchemical factory approach offers a safer and scaleable approach to producing materials from the very smallest quantities to the largest bulk. |
Chemistry World July 23, 2015 Richard Massey |
Photoredox catalysis mechanisms seen in new light A debate over whether photoredox-catalyzed reactions proceed via chain processes may now be settled, thanks to new mechanistic insight brought to light by scientists in the US. |
Chemistry World November 5, 2015 Emma Stoye |
Unnatural nanoreactor puts click reaction in the spotlight A protein 'nanoreactor' that can monitor a click chemistry reaction at the level of single molecules has been created by adding an unnatural amino acid to a nanopore. |
Chemistry World November 6, 2008 James Mitchell Crow |
Double reactor makes hydrogen and syngas Two chemical reactions key to producing future fuels can be linked together in a single membrane-based reactor to increase their efficiency, say Chinese chemists. |
Chemistry World February 20, 2012 James Urquhart |
Unusual kinetics of catalyst revealed US researchers have elucidated the unusual reaction kinetics of C-H activation by the palladium(II) catalyst (Pd(OAc) 2). |