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Chemistry World
May 6, 2008
James Mitchell Crow
Building Peptides From the Wrong End UK chemists have cracked a long-standing problem in peptide synthesis that has prevented amino acid chains being grown from both ends. The insight could open up efficient ways to make peptide-based drugs. mark for My Articles similar articles
Chemistry World
July 2, 2014
Tim Wogan
Miller's forgotten experiments point to primitive protein genesis Stanley Miller's experiments are still adding to our understanding of prebiotic Earth. mark for My Articles similar articles
Chemistry World
August 2, 2011
Phillip Broadwith
Protein synthesis hijacked to turn out cyclic peptides Japanese researchers have developed a way of reprogramming the genetic code and using bacteria to make and screen huge libraries of cyclic peptides using unnatural amino acids. mark for My Articles similar articles
Chemistry World
March 16, 2014
Simon Hadlington
Short peptides self-assemble into a catalyst Researchers in the US have created catalysts from peptide chains that are only seven amino acids long. mark for My Articles similar articles
Geotimes
October 2004
Laura Stafford
Volcanic gas and early life Researchers have combined carbonyl sulfide with free amino acids in a reaction that created di-, tri- and tetra-peptides. The experiment was conducted under a variety of conditions meant to simulate Earth's early atmosphere. mark for My Articles similar articles
Chemistry World
February 7, 2007
Bea Perks
Protein's Non-Natural Alternative Beta peptides are of interest because of what they can tell researchers about protein folding in general. Now, chemical biologists have built what they say is a 'remarkably protein like' structure from beta peptides. mark for My Articles similar articles
Chemistry World
July 26, 2007
Richard Van Noorden
Shortcut Protein Synthesis Ditches Amino Acids Chinese chemists have demonstrated a speedy way to make polypeptides by avoiding the costly tedium of linking together amino acids. mark for My Articles similar articles
Chemistry World
June 17, 2013
Eleanor Merritt
Switching chirality in amino acids An international team of scientists has developed a purely chemical approach to interconvert L- and D-amino acids. This method could rival enzymatic routes used in industry, and enable cheaper production of some pharmaceuticals. mark for My Articles similar articles
Chemistry World
October 16, 2008
Hayley Birch
Miller's legacy: new clues to origins of life Scientists have re-examined dried residues in 50-year-old vials from classic 'primordial soup' experiments to glean new information about how life originated on Earth. mark for My Articles similar articles
Chemistry World
October 9, 2006
Michael Gross
Miniature Microbicides Researchers have created miniature antimicrobial peptides that contain only four (as opposed to the usual 12-50) amino acid residues combined with a fatty acid. mark for My Articles similar articles
Chemistry World
June 11, 2009
James Urquhart
Enzyme-free assembly of DNA-like molecules US scientists have developed a simple peptide nucleic acid system that self-assembles and adapts to new instructions without enzymes. mark for My Articles similar articles
Chemistry World
September 12, 2010
Mike Brown
Comet shockwaves helped stimulate life on Earth The shock waves caused as comets hit the early Earth could have helped promote the formation of amino acids and the early building blocks of life, say US researchers. mark for My Articles similar articles
Chemistry World
March 17, 2015
Andy Extance
Reaction map suggests meteorite chemistry route to life UK chemists have found a reaction network that they believe shows that 'pretty much everyone' working on life's molecular origins is wrong -- but also 'right, in a sense'. mark for My Articles similar articles
Chemistry World
January 19, 2010
Simon Hadlington
New 'click' reaction to modify proteins Chemists in the US have discovered a new way to attach small molecules to proteins and peptides under mild, aqueous reaction conditions. mark for My Articles similar articles
Chemistry World
January 10, 2013
Laura Howes
Rotaxane mimics ribosome to spin out peptides The field of molecular machines has taken a new bio-inspired turn to assemble another molecule, in this case linking up individual amino acids into a peptide. mark for My Articles similar articles
Chemistry World
June 4, 2008
Lewis Brindley
Peptide printer goes into overdrive Synthesizing arrays of short peptides could soon be as easy as printing them out - thanks to the development of a modified laser printer that uses amino acids instead of colored ink. mark for My Articles similar articles
Chemistry World
September 7, 2014
Michael Gross
Bringing chemical synthesis to the masses The promise of a novel approach to building chemical libraries, which only requires simple building blocks in water, without any additional reagents or sample preparation, is inspired by nature. mark for My Articles similar articles
Chemistry World
May 12, 2008
Simon Hadlington
'Super-yeast' tackles unnatural proteins Researchers in the US have engineered yeast cells to produce large amounts of proteins containing unnatural amino acids (UAAs) - a feat that has previously only been possible with bacteria. mark for My Articles similar articles
Chemistry World
September 16, 2014
Patrick Walter
Computer simulations point to formamide as prebiotic intermediate in 'Miller' mixtures Formamide may have played a key role in the genesis of life mark for My Articles similar articles
Chemistry World
March 21, 2011
Michael Gross
Origin of life experiments revisited Modern analysis of forgotten samples has given chemists in the US additional insights the origins of life on Earth. mark for My Articles similar articles
Chemistry World
March 2, 2007
Philip Ball
Giving Life a Hand Why are proteins left-handed and nucleic acids right-handed? Once offered only a few sketchy theories, scientists have found more alternatives for creating homochirality. mark for My Articles similar articles
Chemistry World
November 3, 2008
Simon Hadlington
Organic synthesis set for auto-pilot Peptides are routinely made by machines that couple together amino acid components. Could organic synthesis ever get this simple? mark for My Articles similar articles
Chemistry World
August 28, 2011
Simon Hadlington
Synthetic self-assembling collagen for tissue engineering US researchers have succeeded in making the most realistic synthetic collagen to date. mark for My Articles similar articles
Chemistry World
November 1, 2009
Hayley Birch
How light gave life a helping hand A new theory for how 'handedness' in organic molecules evolved has been proposed by Dutch scientists. mark for My Articles similar articles
Chemistry World
August 13, 2015
Heather Powell
Study probes role of chemical corruption in origin of life Researchers are incorporating what they describe as defective compounds into their experiments to help them understand how the first molecules of life formed. mark for My Articles similar articles
Chemistry World
April 8, 2008
Mark Peplow
Meteorite Source for Life's Handedness Scientists have long speculated that life's preference for left-handed amino acids may have been triggered by compounds brought to Earth by meteorites. Now they've shown exactly how two crucial steps in this process could happen. mark for My Articles similar articles
Chemistry World
February 11, 2013
Philip Ball
A (chemical) potential theory of life's origin This theory says that life arose at hydrothermal vents, not merely because these provide heat and the ingredients for making complex organics but because they create sustained gradients of ion concentration. mark for My Articles similar articles
Chemistry World
August 20, 2008
Spying on Self-Assembly Proteins attaching to gold nanoparticles don't mill around randomly, but organise into clusters, according to UK scientists who say they have for the first time spied in detail peptides assembling on a surface. mark for My Articles similar articles
Chemistry World
October 8, 2008
Sarah Houlton
Artificial protein chemistry licensed to industry UK researchers are licensing to industry their method of making artificial proteins by chemically modifying individual amino acid structures. mark for My Articles similar articles
Chemistry World
January 13, 2012
Helen Potter
Mineral regulates early metabolism Chinese scientists have taken a step towards further understanding the reactions that led to the origin of life by showing that a crucial metabolic process can be photocatalysed on the surface of a common mineral. mark for My Articles similar articles
Chemistry World
November 26, 2010
Amaya Camara-Campos
Enriching the origin of life theory An enantioenrichment of the amino acid valine, which could shed light on the origin of chirality on Earth, has been achieved by scientists in Spain. mark for My Articles similar articles
Chemistry World
March 30, 2011
Hayley Birch
Amino acid synthesis hints at how the genetic code expanded The detailed pathway for the biosynthesis of pyrrolysine - the 22nd and latest amino acid to be discovered - has been outlined by US researchers. mark for My Articles similar articles
Chemistry World
June 16, 2014
James Urquhart
Handshake assembles new emulsions All it takes to make new stable emulsions with tuneable and novel properties is to give a simple mixture of water, solvent and peptide derivatives a quick shake by hand. mark for My Articles similar articles
Chemistry World
July 15, 2010
Simon Hadlington
Synthetic enzyme catalyses Diels-Alder reaction The reaction is key to many organic syntheses and suggests that artificial enzymes could soon become part of the synthetic chemist's toolkit. mark for My Articles similar articles
Chemistry World
August 7, 2011
Phillip Broadwith
Possible Origin of Chirality in the Rna World Given a tiny push one way or the other, simple racemic precursors can lead to the chiral building blocks of RNA using a combination of chemical and physical factors. mark for My Articles similar articles
Chemistry World
December 8, 2008
Hayley Birch
Meteorites hitting oceans may have kick-started life Japanese scientists have done laboratory experiments to test the idea. mark for My Articles similar articles
Chemistry World
May 12, 2010
Phillip Broadwith
Tying up spider silk's loose ends The way spider silk proteins can be stored as a fluid but spun instantly into fibres is all down to their end parts, European scientists have discovered. mark for My Articles similar articles
Chemistry World
December 20, 2007
Richard Van Noorden
Off-the-Peg Organic Synthesis Goes Commercial Chemists have created an efficient way to make small molecules by repeatedly using just one coupling reaction to clip together pre-prepared chemical fragments is going commercial. mark for My Articles similar articles
Chemistry World
April 12, 2012
Alisa Becker
Nanoscale engineering of wound beds A collagen-binding peptide with applications in wound healing has been developed by scientists in the US. mark for My Articles similar articles
Chemistry World
October 14, 2009
James Urquhart
New route to amino acids US scientists have found a new way of making a class of non-natural amino acids that are widely used as components of pharmaceuticals and chiral catalysts. mark for My Articles similar articles
Chemistry World
February 3, 2012
Simon Hadlington
Toxic mushroom behind Chinese deaths unmasked Chinese scientists believe they have identified the toxic assassins responsible for the mysterious deaths of hundreds of people in one of the country's provinces over the past 30 years. mark for My Articles similar articles
Chemistry World
October 26, 2006
Victoria Gill
Volcanoes Reveal the Secret of the Origin of Life Life began with a chemical reaction under the sea over four billion years ago. That is the claim of a German scientist whose team has recreated a crucial part of the reaction, synthesizing all the necessary ingredients for a living organism. mark for My Articles similar articles
Chemistry World
November 5, 2015
Emma Stoye
Unnatural nanoreactor puts click reaction in the spotlight A protein 'nanoreactor' that can monitor a click chemistry reaction at the level of single molecules has been created by adding an unnatural amino acid to a nanopore. mark for My Articles similar articles
Geotimes
November 2004
Jay Chapman
Impacting the Origin of Life Impact events and meteorite strikes are often associated with mass extinctions and widespread devastation. But, despite this destructive reputation, impact events may have played a role in the evolution of life, according to several new studies. mark for My Articles similar articles
Chemistry World
September 25, 2014
Simon Hadlington
First interstellar sighting of a branched alkyl molecule The radiotelescope in Atacama, Chile, has found the first branched molecule ever seen in interstellar space mark for My Articles similar articles
Pharmaceutical Executive
November 1, 2006
Thoughtleader: Making Things Stick Ambrx has created the "glue" that allows researchers to attach activity-enhancing molecules to amino acids where they couldn't before. mark for My Articles similar articles
Chemistry World
December 20, 2012
Laura Howes
Cutting edge chemistry in 2012 This year saw more work probing the nature of bonding. In Germany, Holger Braunschweig found that reacting a bis(N-heterocyclic carbene)-stabilized tetrabromodiborane with sodium naphthalene gave diborene or diboryne compounds with the world's first stable boron -- boron triple bond. mark for My Articles similar articles
Chemistry World
October 27, 2014
Tim Wogan
Folding rules used to build unnatural proteins Scientists in the UK and US have designed and synthesized unnatural protein structures, using theoretical calculations to explore the factors affecting protein folding and stability. mark for My Articles similar articles
Chemistry World
March 4, 2011
Russell Johnson
Tracking the early stages of Alzheimer's disease UK researchers can track the early steps of formation of peptide clumps linked to Alzheimer's disease using the peptide's fluorescent ability. This could help design effective therapies for the disease at an early stage. mark for My Articles similar articles
Chemistry World
June 17, 2012
Jon Evans
Anti-social amino acids gang up Previously thought to be purely the preserve of proteins and peptides, scientists have discovered that the amino acid phenylalanine can form the toxic amyloid fibrils that are a hallmark of diseases such as Alzheimer's and Parkinson's. mark for My Articles similar articles