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Bio-IT World
October 10, 2003
Jeffrey Skolnick
Protein Structure Prediction in Drug Discovery Indications are that structure prediction can assist in the automated assignment of proteins to known pathways. mark for My Articles similar articles
Chemistry World
October 27, 2014
Tim Wogan
Folding rules used to build unnatural proteins Scientists in the UK and US have designed and synthesized unnatural protein structures, using theoretical calculations to explore the factors affecting protein folding and stability. mark for My Articles similar articles
Bio-IT World
June 12, 2002
Mark D. Uehling
Putting Proteins in Their Place Will a 'periodic table' of proteins help classify the ungainly beasts? mark for My Articles similar articles
Wired
July 2001
Oliver Morton
Gene Machine IBM took a dare: Build a supercomputer that predicts the invisible process of protein folding. Spend $100 million, increase processing speed 100-fold, and revolutionize the field. Then convince the biologists it matters... mark for My Articles similar articles
Wired
John Bohannon
Gamers Unravel the Secret Life of Protein A look at the protein chemistry world's biennial World Series, a competition to see who can predict the shape a protein will fold into, knowing nothing more than the sequence of its constituent parts. mark for My Articles similar articles
Chemistry World
April 29, 2013
Caryl Richards
Protein origami sets scene for designer structures A world first in the art of protein origami has been attained with a novel method of folding a polypeptide chain into a three-dimensional tetrahedron. mark for My Articles similar articles
HHMI Bulletin
February 2011
Michele Solis
Right Before Your Eyes Coupling protein sequence to function, thousands of variants at a time. mark for My Articles similar articles
Chemistry World
November 13, 2014
Katrina Kramer
Persuading proteins to form porous polyhedra Researchers in the US have designed a hollow cube out of naturally occurring proteins, something that was previously only possible with DNA. mark for My Articles similar articles
Bio-IT World
December 10, 2002
Kevin Davies
Do Try This @ Home In the most impressive sign of distributed computing's awesome potential in biology thus far -- at least in peer-review literature -- researchers have simulated the folding of a mini-protein on a microsecond timescale. mark for My Articles similar articles
Industrial Physicist
Jennifer Ouellette
Bioinformatics moves into the mainstream An explosion of data is being tamed with new systems mark for My Articles similar articles
Chemistry World
October 27, 2006
Richard Van Noorden
Synthetic Origami Folds Like Natural Enzymes Researchers have synthesised a large organic molecule that folds up like a small protein, though its backbone is entirely non-biological. The achievement is a step along the path to producing truly synthetic enzymes in the laboratory. mark for My Articles similar articles
Bio-IT World
November 2006
John Russell
On the CASP of a DREAM A meeting to evaluate the results of the CASP (Critical Assessment of Techniques for Protein Structure Prediction) 7 predictions is scheduled for this month. mark for My Articles similar articles
Chemistry World
November 2006
Philip Ball
Opinion: The Crucible Here are some of the latest instalments in the ongoing story of how protein misfolding causes neurodegenerative diseases -- a story that is not solely about developing clinical treatments or preventative medicines, but which goes to the heart of proteins' role as the stuff of life. mark for My Articles similar articles
Chemistry World
June 1, 2012
Simon Hadlington
Protein architecture with atomic precision Researchers have made a key breakthrough in designing and building geometrically defined nanostructures from proteins with unprecedented accuracy. mark for My Articles similar articles
HHMI Bulletin
Feb 2012
An Intentional Life Scientists have identified a number of genes associated with familial forms of ALS, and Arthur Horwich has homed in on one of them. mark for My Articles similar articles
HHMI Bulletin
May 2010
Richard Saltus
A Silver Lining Sure, some prions can cause diseases, but others are turning out to be beneficial. mark for My Articles similar articles
Chemistry World
December 21, 2006
Henry Nicholls
Silent SNPs Serve up a Structural Surprise The sequence of amino acids no longer dictates the structure and function of a protein according to a surprising new paper. mark for My Articles similar articles
Chemistry World
February 3, 2013
Andy Extance
Enzyme draws nanopore protein sequencing nearer US scientists at the University of California, Santa Cruz, have made a key step towards nanopore protein sequencing, thanks to an 'unfoldase' enzyme. Mark Akeson's team exploited this enzyme to unravel proteins and pull them through nanopores. mark for My Articles similar articles
HHMI Bulletin
Winter 2013
Nicole Kresge
A Structural Revolution Over the years, scientists and artists have used an assortment of techniques to showcase molecular structure. mark for My Articles similar articles
Chemistry World
April 2009
Philip Ball
Column: The crucible Unwinding protein fibrils could give a glimpse of how peptides survived on early Earth mark for My Articles similar articles
Chemistry World
November 27, 2013
Jennifer Newton
A cytochrome from scratch Artificial proteins could be closer to participating in natural biochemical pathways after researchers show that bacteria will process amino acid sequences entirely unrelated to any natural protein to produce a fully functioning cytochrome. mark for My Articles similar articles
Wired
April 2001
David Ewing Duncan
The Protein Hunters Step One: Crack the genome. Step Two: Unlock the molecular structure of amino acids. Step Three: Get ready for the robo-fast, custom-drug future... mark for My Articles similar articles
Chemistry World
February 13, 2014
Philip Ball
Ice core to antifreeze protein's inner workings The antifreeze protein that protects the winter flounder from sub-zero temperatures has been found to have an odd structure. mark for My Articles similar articles
Chemistry World
September 29, 2010
Hayley Birch
Protein folding: knotted or not A new study may help scientists unravel the complex problem of protein folding. The study suggests knotted proteins, which present a particular challenge to folding experts, could be untied with a couple of well-targeted tugs. mark for My Articles similar articles
HHMI Bulletin
Fall 2012
Ingfei Chen
Same But Not Equal A code within the genetic code explains why identical proteins are produced at varying speeds. mark for My Articles similar articles
Chemistry World
June 25, 2013
Michael Gross
A foaming protein from the horse's mouth Researchers in the UK have solved the structure of this protein, yielding tantalizing hints to a novel kind of surface activity and to evolutionary connections to other examples. mark for My Articles similar articles
Chemistry World
August 26, 2008
Fred Campbell
High-throughput protein microarrays on the way A new method to rapidly generate protein microarrays has been developed by UK researchers at the University of Manchester. mark for My Articles similar articles
HHMI Bulletin
Spring 2013
Nicole Kresge
A Structural Toolbox Natalie Strynadka wants to design a better antibiotic. Her strategy: learn about the molecules bacteria use to invade cells. Her tool: structural biology. mark for My Articles similar articles
HHMI Bulletin
Fall 2012
Halleh B. Balch
Like a Chinese Finger Trap In neurodegenerative diseases like Alzheimer's, the needle-like fibers that accumulate in the brain are not the real damage-doers. The culprits are intermediate protein structures, called small amyloid oligomers, made of a few proteins that misfold and aggregate. mark for My Articles similar articles
Chemistry World
October 8, 2008
Sarah Houlton
Artificial protein chemistry licensed to industry UK researchers are licensing to industry their method of making artificial proteins by chemically modifying individual amino acid structures. mark for My Articles similar articles
Bio-IT World
April 15, 2003
Malorye Branca
Beyond the Blueprint How will the wealth of data emanating from the human genome and allied technologies impact research on health and disease? mark for My Articles similar articles
Chemistry World
July 6, 2007
Michael Gross
Predicting How Proteins Fold Researchers in Italy and the UK have now developed a computational approach that can simulate the folding of membrane proteins in atomic detail. mark for My Articles similar articles
Chemistry World
July 15, 2010
Simon Hadlington
Synthetic enzyme catalyses Diels-Alder reaction The reaction is key to many organic syntheses and suggests that artificial enzymes could soon become part of the synthetic chemist's toolkit. mark for My Articles similar articles
Prepared Foods
February 2008
Sharon Book
Article: Protein Ingredients for Health and Texture A variety of soy, dairy and egg proteins are available for the food formulator to obtain the desired texture in a food or beverage. mark for My Articles similar articles
Chemistry World
June 2009
Michael Gross
Bubble-wrapped frogs Tropical frogs create remarkable protein foams to protect their spawn. Exploration of the underlying chemistry has only just begun mark for My Articles similar articles
HHMI Bulletin
February 2012
Sarah C. P. Williams
Force Factor In the context of cells, forces are required to move molecules. Quantifying these forces gives scientists a way to compare and contrast different molecular motors. mark for My Articles similar articles
Chemistry World
February 7, 2007
Bea Perks
Protein's Non-Natural Alternative Beta peptides are of interest because of what they can tell researchers about protein folding in general. Now, chemical biologists have built what they say is a 'remarkably protein like' structure from beta peptides. mark for My Articles similar articles
Bio-IT World
November 2006
Briefs Supercomputer vs Superbug... Clinphone Buys; Phase Forward Thrives... Illumina Wins Amgen Deal... CASP's Protein Prodigals... mark for My Articles similar articles
Bio-IT World
August 15, 2005
Robert M. Frederickson
What's 'Post' About Postgenomic? Bioinformatics tools can help organize and study genomic sequences that were discovered in the '90s. The tools help with tasks like analyzing gene expression, predicting protein structure and function, and establishing networks of interacting protein in cells. mark for My Articles similar articles
Bio-IT World
June 2006
Kevin Davies
David Shaw: No Hedging on Future of Computer Simulations The computational scientist who founded the world's largest alternative investment firm says he is two years away from building a new breed of computer that could be a major breakthrough in structural biology -- simulating the process of protein folding and protein-drug interactions. mark for My Articles similar articles
Chemistry World
March 23, 2012
Michael Gross
Molecular chaperones caught on film Researchers have combined thousands of snapshots of the barrel-shaped protein GroEL to create a series of films that follow its movement and binding events. mark for My Articles similar articles
Chemistry World
March 16, 2014
Simon Hadlington
Short peptides self-assemble into a catalyst Researchers in the US have created catalysts from peptide chains that are only seven amino acids long. mark for My Articles similar articles
Science News
October 14, 2006
Ivars Peterson
Knots in Proteins Knotted proteins are rare, but more than just random occurrences. The secret of spontaneous knotting lies in the mathematics of self-avoiding random walks. mark for My Articles similar articles
Chemistry World
January 12, 2015
Emma Stoye
Protein mutant libraries to probe diseases' genetic link quickly and cheaply Researchers in the US have developed a faster and less costly way to investigate the effects of genetic mutations on proteins, which should offer new insights into hereditary diseases. mark for My Articles similar articles
Industrial Physicist
Aug/Sep 2003
Ineke Malsch
Protein research calls for advanced instruments The science of protein interactions is becoming a major tool in biomedical and drug development research. Carrying out and advancing such studies more efficiently and effectively, however, will require new, cutting-edge instrumentation. mark for My Articles similar articles
Technology Research News
January 1, 2003
Eric Smalley
Altered protein orders metal bits Researchers from NASA, the SETI Institute and Argonne National Laboratory have genetically modified a bacteria that lives in geothermal hot springs in order to make a microscopic scaffolding that produces a high-tech material. mark for My Articles similar articles
Reactive Reports
Issue 51
David Bradley
Protein Crystals Trapped Researchers have developed a new technique for crystallizing proteins, which could open up a whole range of materials to this powerful analytical technique. mark for My Articles similar articles
Technology Research News
March 24, 2004
DNA has nano building in hand Researchers from Ludwig Maximilians University in Germany have built a simple molecular machine from DNA that can bind to and release single molecules of a specific type of protein. mark for My Articles similar articles
Chemistry World
September 14, 2011
Laura Howes
Aspirin Still Has Some Secrets Left to Give up The overlooked stereoelectric effect in aspirin makes the molecule less polar, which may improve the drug's bioavailability. mark for My Articles similar articles
Chemistry World
July 31, 2012
David Bradley
Hydrogels can release drugs one at a time A hydrogel that can be programmed to release different protein drugs one after the other rather than all at once could simplify the delivery of complex therapeutic regimens for various diseases. mark for My Articles similar articles