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HHMI Bulletin
Aug 2011 |
Plant Science Gets a Boost HHMI and the Gordon and Betty Moore Foundation join forces to fund plant scientists.   |
HHMI Bulletin
Nov 2010 |
Vicki Chandler: Plants Contribute Basic Biological Lessons to Science" Vicki Chandler's research on how plants regulate their genes may ultimately inform studies of human diseases. She's leading the Gordon and Betty Moore Foundation's partnership with HHMI to support more of this kind of fundamental plant science. |
HHMI Bulletin
Aug 2011
Cassandra Willyard |
A Faster Knockout With a virus, a needle, and an ultrasound machine, researchers have drastically cut the time it takes to disable a gene in mice. |
HHMI Bulletin
Aug 2010
Sarah C.P. Williams |
Switching Plants' Reproductive Methods The shipments of seeds that farms rely on at the beginning of each growing season could soon be a relic of the past. Scientists have discovered how to coax plants to clone themselves by altering their reproductive methods. |
HHMI Bulletin
February 2011
Sarah C.P. Williams |
Enforcing Order Changing the spatial arrangement of molecules in a cell can alter their functions. |
Chemistry World
July 21, 2011
Elinor Richards |
Cell Control to Change Cell Function US scientists can now control the reactions occurring inside cells. |
HHMI Bulletin
Winter 2013
Amber Dance |
A Trick of Light When miniSOG protein takes in blue light, it converts ordinary oxygen into a short-lived, excited state called singlet oxygen, which reacts with and changes the molecules around it. The singlet oxygen destroys the mitochondria's delicate machinery. |
Chemistry World
April 19, 2007
John Bonner |
Storm in a Buttercup Botanists have spent 70 years puzzling over the identity of the chemical agent responsible for initiating the flowering process in plants. That mystery has now been solved by two separate research groups in Germany and Japan. |
Chemistry World
January 4, 2007
Henry Nicholls |
Microscopic Lab Investigates Contents of a Cell It's small-scale science that could have a massive impact on research into cell biology. Scientists have produced a microscopic laboratory where they can count individual proteins in a single cell. |
HHMI Bulletin
February 2011
Sarah C.P. Williams |
Releasing the Brakes on Cell Fate Converting one cell type directly into another is a kind of modern-day alchemy, an ultimate goal in biological research. But unlike turning base metals into gold, changing a cell's identity is feasible, new research shows. |
HHMI Bulletin
May 2012
Elise Lamar |
Cells on the Move The biochemical signals that set cells on a journey are as diverse as the tissues they move through, but the engine is driven by constant remodeling of a protein network built from a box of cellular Legos. |
Scientific American
December 2008
Tim Hornyak |
Turning Back the Cellular Clock: A Farewell to Embryonic Stem Cells? Shinya Yamanaka discovered how to revert adult cells to an embryonic state. These induced pluripotent stem cells might soon supplant their embryonic cousins in therapeutic promise |
Popular Mechanics
November 27, 2007
Alex Hutchinson |
Stem Cells 2.0: Beyond the Hype, Engineers Look to Build Fast Engineers play the important role of making lab bench discoveries reproducible and efficient for use in industry. |
Bio-IT World
July 15, 2003
Julia Boguslavsky |
'Fingerprinting' a Single Cell Single-cell proteomics is finally within reach, thanks to a professor of analytical chemistry. |
Chemistry World
May 26, 2011
Russell Johnson |
Hunting elusive green fluorescent proteins After a 40 year hunt, scientists have tracked down the genes responsible for fluorescent proteins in Obelia medusa - a type of jellyfish. Knowledge of these genes could lead to new fluorescent protein tags for use in cell biology. |
HHMI Bulletin
Aug 2010
Richard Saltus |
Three-Dimensional Cell Cultures Thinking big but starting small, Sangeeta Bhatia is closing in on her ambitious goal: growing human livers in the lab from scratch. |
Science News
February 21, 2004
Ivars Peterson |
Computing on a Cellular Scale John Conway, a British mathemetician at Princeton University, has created a cellular game that is unpredictable. In studying the behavior of leaf pores, physicist David Peak, biologist Keith A. Mott, and their coworkers at Utah State University in Logan found that stomata activity resembles that of cellular automata able to perform specific computational tasks. |
HHMI Bulletin
May 2010
Robert Tjian |
Biomolecular Crowdsourcing A generation of web-savvy entrepreneurs has found a relatively cheap and effective approach to solving complex problems and soliciting ideas: toss out a challenge into a vibrant digital community and watch what happens. |
Wired
August 2003
Jennifer Kahn |
The End of Cancer (As we Know it) Diagnosis. Chemotherapy. Radiation. Slow painful death. No more. A new era of cancer treatment is dawning. Meet three scientists who are using the revelations of the Human Genome Project to reshape medicine. |
Scientific American
June 2005
JR Minkel |
RNA to the Rescue The spectacular discovery that a species of plant can summon up genes its parents have lost highlights biologists' increasing recognition of RNA as a more versatile and important molecule in its own right. |
HHMI Bulletin
Aug 2010
Sarah C.P. Williams |
Fruit Fly Cells Don't All Know What Sex They Are HHMI scientists have now found that many cells in male and female fruit flies not only look the same, they are more identical at a molecular level than was previously thought. |
Scientific American
July 2008
Sally Lehrman |
Dolly's Creator Moves Away from Cloning and Embryonic Stem Cells Like many stem cell pioneers, Ian Wilmut, the creator of Dolly the sheep, has jumped to an alternative approach. Is this the beginning of the end for embryonic cloning? |
IEEE Spectrum
August 2006
Schoenbach et al. |
Zap Extreme voltage could be a surprisingly delicate tool in the fight against cancer. The list of effects that scientists have achieved using nanoseconds-long pulses is growing rapidly, though their actual use as a medical treatment is still years away. |
Chemistry World
November 12, 2009
Hayley Birch |
New drug design looks top Notch against cancer A new type of drug that can block the switching on of certain genes in cancer cells has shown promise in mice. |
Chemistry World
September 8, 2015
Simon Hadlington |
Mutant plant can mop up explosives UK researchers have identified a mutant plant that is able to thrive on soil contaminated with high concentrations of the explosive TNT. |
Chemistry World
February 7, 2006
Jon Evans |
Plant-Derived Drug Approved in US Dow AgroSciences has become the first biotech firm to gain US regulatory approval for a plant-derived drug. The company claims it will be able to manufacture many other vaccines, for animal and human diseases, using its plant-based production technology. |
Reason
October 2001
Ronald Bailey |
Blastocyst Brouhaha Which human cells count as people? |
HHMI Bulletin
Fall 2012
Elise Lamar |
Push and Pull Jennifer Zallen, an HHMI early career scientist at Memorial Sloan-Kettering Cancer Center, studies how embryonic tissues stretch along an anterior-posterior axis using the fruit fly Drosophila melanogaster as a model system. |
Chemistry World
April 2010 |
Column: The crucible We are getting better at manipulating cells to grow into the tissues we need. Chemical factors are key, says Philip Ball |
HHMI Bulletin
May 2012
Nicole Kresge |
Locating a Genetic Glitch A team of 41 scientists led by HHMI investigator Louis Ptacek has pinpointed the gene responsible for a rare disease that causes sudden, uncontrollable movements. The culprit is a little known protein that may be responsible for communication between neurons. |
Scientific American
June 2008
Melinda Wenner |
How Cells Make Use of Random Biochemical Reactions New studies reveal how cells exploit biochemical randomness. |
Bio-IT World
February 11, 2005
Kevin Davies |
In Living Color Researchers have developed a palette of fluorescent proteins to complement the green fluorescent protein (GFP), a stable of cell biology for a decade. |
Chemistry World
June 9, 2008
Simon Hadlington |
Artificial virus silences genes Scientists in Korea have created an artificial virus that can target the nucleus of cancer cells and knock out specific genes. |
Scientific American
January 2009
Charles Q. Choi |
Do White Blood Cells Make Cancer Deadly? The ability to spread underlies the killing power of cancer. The process occurs, John Pawelek thinks, when tumor cells fuse with white blood cells -- an idea that, if right, could yield new therapies |
Chemistry World
April 9, 2008
Henry Nicholls |
How plants shudder at shade Scientists claim to have worked out how plants channel energy away from leaves and into spindly shoots, a natural but at-times infuriating response to a bit of shade. Plants are sensitive to the wavelength of light that's reaching them. |
Chemistry World
March 29, 2009
Lewis Brindley |
Gene gels pump out proteins Gels made with genes incorporated into the structure could soon make protein production cheaper and easier, according to researchers in the US. |
Chemistry World
August 15, 2007
John Bonner |
Chemists Claim Biological Alchemy South Korean chemists say they have turned muscle cells from the sole of a human foot into something akin to stem cells, using a simple molecule called neurodazine. |
Bio-IT World
August 15, 2005
Robert M. Frederickson |
What's 'Post' About Postgenomic? Bioinformatics tools can help organize and study genomic sequences that were discovered in the '90s. The tools help with tasks like analyzing gene expression, predicting protein structure and function, and establishing networks of interacting protein in cells. |
Reactive Reports
September 2005
David Bradley |
When Good Turns Bad Prions, the protein-like pathogens at the heart of the fatal brain disorder CJD, so-called mad cow disease, and related diseases can rapidly "remodel" good proteins into bad, according to US scientists, who have demonstrated this for the first time in living cells. |
HHMI Bulletin
Nov 2010
Robert Tjian |
President's Letter Announces Plant Science Funding "Plant scientists have tremendous potential to help us understand -- and possibly find solutions to -- some of the most pressing concerns that face society." |
BusinessWeek
May 24, 2004
Arlene Weintraub |
Repairing The Engines Of Life Can research into stem cells and other advanced techniques heal ailing hearts and brains? U.S. labs are hamstrung by the federal government. |
HHMI Bulletin
February 2011
Michele Solis |
Right Before Your Eyes Coupling protein sequence to function, thousands of variants at a time. |
Popular Mechanics
October 2000 |
Science: Greatest Unsolved Mysteries Is there a Fountain of Youth? Will we cure cancer? Can we achieve immortality? Can we create artificial life? Where is the soul? Is the speed of light the ultimate speed limit? Is there other intelligent life in the universe? Can we travel through time? |
Chemistry World
July 28, 2009
Michael Gross |
DNA to direct and switch off chemo Researchers in the US have developed a new approach to cancer chemotherapy using short DNA strands to help target delivery of the drug directly to cancer cells, and 'call it off' should problems arise. |
Chemistry World
November 25, 2013
Carla Pegoraro |
Steering cells towards biocomputers Bacterial toxins that undergo unique cell interactions have been used to perform logic functions by researchers in Germany. This innovation will help push the limits of synthetic biology. |
Geotimes
February 2005
Sara Pratt |
Reaching Past Heights A new method of calculating paleoelevations using the stomata, or breathing pores, on fossilized leaves may have promise in constructing the past heights of the landscape. |
Fast Company
March 2008
Elizabeth Svoboda |
Eureka? Alan Trounson, the new president of California's stem-cell agency, talks about the science, the opposition, and his qualms about working with embryos. |
The Motley Fool
November 28, 2007
Brian Orelli |
Stem Your Expectations of Stem-Cell Discoveries Making "stem" cells out of skin cells isn't all it's cracked up to be. The recent discovery has a long way to go before it can catch up to the research currently being done with stem cells. |
The Motley Fool
November 9, 2004
Charly Travers |
Are Stem Cells a Rule Breaker? Does the science offer real hope or just hype? Biotech investors take on enough risk in the normal course of drug development that they do not need to worry about whether or not the underlying technology even works. |
Scientific American
July 2008
Charles Q. Choi et al. |
News Scan Briefs: Eating with Tension, Cancerous Marriage, Milk and Diabetes News items from ecology, oncology, immunology, and news about privacy concerns |
