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Chemistry World June 2, 2006 Jon Evans |
Axons Get Directions Scientists are a step closer to understanding the processes that control the growth and spread of nerve cells, following the discovery of a protein complex that directs the transport of building material to growing axons. |
HHMI Bulletin February 2011 Brian Vastag |
Hope Floats With a new arsenal of robust models of ALS, drug development may move to the fast track. |
Reactive Reports September 2005 David Bradley |
When Good Turns Bad Prions, the protein-like pathogens at the heart of the fatal brain disorder CJD, so-called mad cow disease, and related diseases can rapidly "remodel" good proteins into bad, according to US scientists, who have demonstrated this for the first time in living cells. |
HHMI Bulletin February 2012 Nicole Kresge |
Protein Precision in the Brain with CSF Two causes of autism arise from opposite cellular mechanisms. Too much or too little protein production at the synapse between neurons can cause autism and intellectual disability. |
HHMI Bulletin Fall 2012 Richard Saltus |
Nerve Tonic A mouse with a random mutation changed forever the way scientists think about how injured nerves die -- and how, conceivably, their death might be delayed or prevented. |
HHMI Bulletin Nov 2010 Sarah C.P. Williams |
Scientists Track Down Genetic Mutations In Record Time Scanning the human genome for a single disease-causing mutation is like taking a copy of War and Peace in a foreign language and searching for one misspelled word |
AskMen.com Jacob Franek |
Future Cures Almost every disease known to man is under constant research and we can hardly go a day without hearing about some advancement or another. Here are a few diseases for which future cures could be looming on the horizon. |
Scientific American July 3, 2006 Jeneen Interlandi |
An Immune Portal Protein may be a key to autoimmune disorders |
HHMI Bulletin Nov 2010 Mitch Leslie |
Immune System Defects Can Cause Obsessive Behavior A shortage of certain immune cells might prompt obsessive-compulsive disorder. |
HHMI Bulletin Winter 2013 Sarah C.P. Williams |
One Foot in Front of the Other In every type of living cell, materials jet around in a similar variety of manners. The way cellular cargo travels depends on its size, where it's headed, how quickly it must arrive, and how much energy is available. |
HHMI Bulletin Winter 2013 Amber Dance |
A Trick of Light When miniSOG protein takes in blue light, it converts ordinary oxygen into a short-lived, excited state called singlet oxygen, which reacts with and changes the molecules around it. The singlet oxygen destroys the mitochondria's delicate machinery. |
Chemistry World June 1, 2009 Phillip Broadwith |
Wider therapeutic possibilities for botulinum toxin Change to a single amino acid in botulinum toxin A causes it to target non-neuronal signalling proteins, potentially widening the product's therapeutic applications |
HHMI Bulletin Feb 2012 Nicole Kresge |
Now You See It, Now You Don't A disappearing receptor could hold the key to beta-cell growth and insulin production. |
HHMI Bulletin May 2010 Sarah C.P. Williams |
Lab-Grown Liver New cell culture system solves problem of growing liver cells. |
HHMI Bulletin February 2011 Sarah C.P. Williams |
Releasing the Brakes on Cell Fate Converting one cell type directly into another is a kind of modern-day alchemy, an ultimate goal in biological research. But unlike turning base metals into gold, changing a cell's identity is feasible, new research shows. |
HHMI Bulletin Spring 2013 Amy Maxmen |
Ring Around the Axon Xiaowei Zhuang and her team used a microscopy technique called STORM to show that actin protein forms evenly-spaced rings around the axons of nerve cells. |
HHMI Bulletin Spring 2013 Nicole Kresge |
Use It or Lose It HHMI investigator Catherine Dulac of Harvard University has uncovered a small molecule that plays a big role in the process of tuning olfactory neurons to the environment. |
Reactive Reports Issue 36 David Bradley |
Sweet solution to Huntington disease? Japanese researchers have discovered that a simple sugar prevents neurodegeneration in a mouse model of the genetic disorder Huntington disease. |
Technology Research News May 5, 2004 Kimberly Patch |
Chaos Seems to Aid Learning Researchers in Japan have built a computer simulation of the inferior olive, a portion of the brain that probably relays errors in movement to the cerebellum. The model shows that chaos can be useful in the brain for efficient learning. |
HHMI Bulletin May 2012 Elise Lamar |
Cells on the Move The biochemical signals that set cells on a journey are as diverse as the tissues they move through, but the engine is driven by constant remodeling of a protein network built from a box of cellular Legos. |
HHMI Bulletin February 2011 Sarah C.P. Williams |
Enforcing Order Changing the spatial arrangement of molecules in a cell can alter their functions. |
HHMI Bulletin Aug 2011 Janelle Weaver |
Leading a Double Life with CSF Lucky for us, the organs in our bodies come with a self-repair kit. Though regularly bombarded by harmful bacteria, more often than not they manage to heal themselves. How this happens has puzzled scientists, but now there may be some answers. |
Scientific American June 2009 Melinda Wenner |
Genetic Copy Variations and Disease A new sense for how variable numbers of genes cause disease. |
HHMI Bulletin May 2010 Ivan Arnato |
Light Moves Light is becoming the tool of choice for researchers who want to precisely manipulate neurons and other cells. |
HHMI Bulletin May 2010 Richard Saltus |
A Silver Lining Sure, some prions can cause diseases, but others are turning out to be beneficial. |
Chemistry World July 21, 2011 Elinor Richards |
Cell Control to Change Cell Function US scientists can now control the reactions occurring inside cells. |
HHMI Bulletin Feb 2012 |
An Intentional Life Scientists have identified a number of genes associated with familial forms of ALS, and Arthur Horwich has homed in on one of them. |
Chemistry World August 24, 2006 Jessica Ebert |
Alzheimer's Researchers Tackle Waste Disposal The memory of mice with Alzheimer's-like symptoms is improved by inoculating the mice with an enzyme involved in protein degradation, report US researchers. The work could lead to new therapies for patients with Alzheimer's disease. |
HHMI Bulletin Nov 2011 Jenni Laidman |
When Membranes Merge Scientists are uncovering details of synaptic signaling between neurons. |
HHMI Bulletin Aug 2010 Sarah C.P. Williams |
Fruit Fly Cells Don't All Know What Sex They Are HHMI scientists have now found that many cells in male and female fruit flies not only look the same, they are more identical at a molecular level than was previously thought. |
HHMI Bulletin Winter 2013 Megan Scudellari |
Tunneling Out A research team including HHMI investigator Melissa Moore at the University of Massachusetts Medical School has discovered an alternative passageway used by RNA -- protein complexes to exit the nucleus. |
The Motley Fool November 28, 2007 Brian Orelli |
Stem Your Expectations of Stem-Cell Discoveries Making "stem" cells out of skin cells isn't all it's cracked up to be. The recent discovery has a long way to go before it can catch up to the research currently being done with stem cells. |
BusinessWeek July 26, 2004 Arlene Weintraub |
The Stem-Cell Flap: Simmer Down Advocates are overstating stem cells' near-term ability to treat grave illnesses. In doing so, they not only distort the science; the hopes they raise among many people who are sick today are also sure to be dashed. |
Chemistry World February 22, 2011 Amaya Camara-Campos |
Repairing faulty genes Israeli scientists have developed compounds that could be better treatments for genetic diseases than current drugs. |
Bio-IT World August 15, 2005 Robert M. Frederickson |
What's 'Post' About Postgenomic? Bioinformatics tools can help organize and study genomic sequences that were discovered in the '90s. The tools help with tasks like analyzing gene expression, predicting protein structure and function, and establishing networks of interacting protein in cells. |
HHMI Bulletin Spring 2013 Nicole Kresge |
Itching to Be Discovered When the receptor for capsaicin -- the chemical that gives heat to chili peppers -- is added to itch-sensing neurons, exposure to the normally painful capsaicin causes itchiness. |
BusinessWeek April 22, 2010 Rob Waters |
Gene Therapy Takes a Turn for the Better Researchers and investors are heartened by advances in gene therapy. Analysts say revenues are still several years off, however. |
The Motley Fool November 9, 2004 Charly Travers |
Are Stem Cells a Rule Breaker? Does the science offer real hope or just hype? Biotech investors take on enough risk in the normal course of drug development that they do not need to worry about whether or not the underlying technology even works. |
Chemistry World October 31, 2008 Manisha Lalloo |
DNA-rewinding protein discovered US scientists have found an enzyme that rewinds sections of DNA whose strands have mistakenly come apart. |
HHMI Bulletin May 2011 Madeline Drexler |
Mark Bear: Charting New Waters Bear has applied his discoveries in brain plasticity to understanding fragile X syndrome, an inherited form of mental impairment. |
Chemistry World June 13, 2011 Laura Howes |
Cells turned into living lasers with fluorescent protein With a little help from a fluorescent protein, mammalian cells have been transformed into living lasers. This discovery could help improve imaging of living cells, enabling researchers to explore what's going on inside. |
Chemistry World October 25, 2007 |
Elusive Drug Target Finally Seen Scientists have captured an atomic-scale picture of a receptor protein from a family that is the target of thousands of drugs. |
Chemistry World August 15, 2007 John Bonner |
Chemists Claim Biological Alchemy South Korean chemists say they have turned muscle cells from the sole of a human foot into something akin to stem cells, using a simple molecule called neurodazine. |
HHMI Bulletin Aug 2010 Richard Saltus |
Three-Dimensional Cell Cultures Thinking big but starting small, Sangeeta Bhatia is closing in on her ambitious goal: growing human livers in the lab from scratch. |
Chemistry World December 21, 2006 Henry Nicholls |
Silent SNPs Serve up a Structural Surprise The sequence of amino acids no longer dictates the structure and function of a protein according to a surprising new paper. |
Chemistry World May 26, 2011 Russell Johnson |
Hunting elusive green fluorescent proteins After a 40 year hunt, scientists have tracked down the genes responsible for fluorescent proteins in Obelia medusa - a type of jellyfish. Knowledge of these genes could lead to new fluorescent protein tags for use in cell biology. |
HHMI Bulletin May 2010 Jeffrey M. Perkel |
A Brighter View of the Brain in Action A protein sensor is beefed up to illuminate the language of neural networks. |
BusinessWeek September 23, 2010 Rob Waters |
Stem Cells That Save Big Pharma a Bundle Drugmakers hope to save big by using stem cells to test drugs for dangerous side effects long before costly human trials are needed. |
Scientific American January 17, 2007 Charles Q. Choi |
A Stroke for Stem Cells The brain becomes a target in stem cell clinical trials. |
Chemistry World January 17, 2011 James Urquhart |
BSE pathogens passed on by air It was generally thought that prions were not transmitted by air, but now scientists have confirmed an airborne route to infection. |