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Chemistry World
December 3, 2009
Simon Hadlington
C-H Bond Activation Takes the Relaxing Route Chemists have uncovered a key factor that helps determine the reactivity of a C-H bond to oxidation. mark for My Articles similar articles
Chemistry World
November 1, 2007
Richard Van Noorden
Step Change for Organic Synthesis US chemists discovered how to attack a complex molecule's unreactive carbon-hydrogen bonds, without resorting to wasteful synthetic aids like protecting and directing groups. mark for My Articles similar articles
Chemistry World
August 2007
Derek Lowe
Opinion: In the Pipeline Process chemists just don't get the credit they deserve. mark for My Articles similar articles
Chemistry World
November 25, 2014
James Urquhart
Nanomolar chemistry enables 1500 experiments in a single day Chemists have conducted over 1500 chemistry experiments in under a day thanks to a miniaturized, high throughput automation platform they developed for identifying how synthetic molecules react under various conditions. mark for My Articles similar articles
Chemistry World
March 22, 2012
Ross McLaren
Back to the future: old reactions to help the new Researchers from the US have delved into the history of organic chemistry to help chemists better predict the effect that functional groups will have on one another within a molecule. mark for My Articles similar articles
Chemistry World
October 2009
Column: In the pipeline Derek Lowe discusses the problem of leaning too heavily on favorite reactions mark for My Articles similar articles
Chemistry World
December 17, 2012
Patrick Walter
RSC acquires rights to Merck Index The Royal Society of Chemistry has acquired the rights to the 'bible' of chemistry, the Merck Index, familiar around the world to medicinal chemists and drug discovery scientists. mark for My Articles similar articles
HHMI Bulletin
Nov 2011
Sarah C.P. Williams.
Carolyn Bertozzi: Changed Expectations Chemists trained in biology were once a rarity -- now they're becoming the norm. mark for My Articles similar articles
Chemistry World
February 22, 2008
James Mitchell Crow
Rhodium Fast Tracks Route to Lactones Chemists in Canada have developed an efficient new way to make lactones, chemical components of many natural products and drugs. mark for My Articles similar articles
Chemistry World
November 3, 2008
Simon Hadlington
Organic synthesis set for auto-pilot Peptides are routinely made by machines that couple together amino acid components. Could organic synthesis ever get this simple? mark for My Articles similar articles
Chemistry World
July 2008
Kevin Rogers
What future for small molecule therapy? Pharmaceutical companies overlook bench chemists at their peril mark for My Articles similar articles
HHMI Bulletin
Nov 2011
Sarah C. P. Williams
Living Chemistry Biologists understand better what chemists can bring to the table. And chemists understand better the questions that biologists really care about. This has led to a bigger impact of chemists on biological problems. mark for My Articles similar articles
Chemistry World
June 24, 2010
Phillip Broadwith
Aryl rings get a fluorine fix A mild and effective method for coupling trifluoromethyl groups on to aryl rings has been developed by US chemists. mark for My Articles similar articles
Chemistry World
April 2007
Derek Lowe
Opinion: In the Pipeline Natural products can be ridiculously complicated. The sheer difficulty of the enterprise is traditionally what made pharmaceutical companies hire people who had worked in total synthesis. But, is total synthesis research still worth the effort? mark for My Articles similar articles
Chemistry World
November 28, 2013
Put the chemistry back in medicinal chemistry Today, synthetic skill is valued and appreciated much less in medicinal chemistry than in chemical development, though it is equally important for both. Much of the blame lies with the mismeasurement of productivity. mark for My Articles similar articles
Chemistry World
September 20, 2007
Lewis Brindley
New Catalyst Rings the Changes Organic chemists in the US have developed a method to control the stereochemistry of a useful intramolecular Diels-Alder reaction. mark for My Articles similar articles
Chemistry World
January 11, 2013
Marie Cote
Following her passion Veronique Gouverneur is professor of chemistry at the University of Oxford, UK. She investigates fluorine chemistry and is working on developing novel synthetic methodologies for the preparation of fluorinated targets. mark for My Articles similar articles
Chemistry World
July 9, 2008
James Mitchell Crow
Pharma goes green to cut costs The pharmaceutical industry's current drive to curb spending is helping to speed the adoption of green chemistry, say experts in the industry. mark for My Articles similar articles
Chemistry World
June 1, 2012
Derek Lowe
Peace, love and understanding You'd think that the chemists and biologists working in drug discovery would understand each other pretty well by now. You would be wrong about that. mark for My Articles similar articles
Chemistry World
February 19, 2010
Simon Hadlington
Forcing stereoselectivity on reactive cations Chemists in the US have devised a dual catalyst strategy to tame the highly reactive iminium ion to give a high degree of stereochemical control over subsequent reactions of the ion. mark for My Articles similar articles
Chemistry World
November 2010
Carbon Couplers Take the Prize Three giants of organic chemistry, who pioneered palladium-catalysed cross coupling reactions, have shared this year's Nobel prize. mark for My Articles similar articles
Chemistry World
May 29, 2015
Derek Lowe
Magic molecule modifiers The synthesis of a new organic molecule can be approached in several ways. mark for My Articles similar articles
Chemistry World
January 17, 2014
Phillip Broadwith
Plug and play redox enzymes With the constant drive to make chemical synthesis ever cleaner, more energy-efficient and generate less waste -- both in research and industrial processes -- more and more chemists are looking to harness enzyme catalysis. mark for My Articles similar articles
Chemistry World
May 30, 2013
Andy Extance
Catalyst duo exerts powerful stereocontrol Chemists from the Swiss Federal Institute of Technology, ETH Zurich, have teamed chiral catalysts in pairs to selectively drive a reaction towards desired stereoisomeric products with high selectivity. mark for My Articles similar articles
Chemistry World
July 3, 2015
Andy Extance
Copper catalysis overcomes double bond trouble Some carbon-carbon double bonds seem too unreactive for synthetic use -- but that's just how chemists in the US are now exploiting them. mark for My Articles similar articles
Chemistry World
November 27, 2009
Simon Hadlington
A simple way to join an olefin to an arene Chemists in the US have developed a simple and effective way to carry out a key class of reaction in organic synthesis - the bolting an olefin to an aromatic ring. mark for My Articles similar articles
Chemistry World
September 2008
Derek Lowe
Column: In the pipeline The author remembers leaving the ivory towers of academe to trade 'unusual and beautiful' for 'useful' mark for My Articles similar articles
Chemistry World
February 22, 2007
Victoria Gill
Women Honoured with International Prize The 2007 L'Oreal Unesco awards for women in science were announced at a ceremony in Paris. This year's selections were based on materials science, so chemistry was well represented in the line-up. mark for My Articles similar articles
Chemistry World
November 27, 2013
Derek Lowe
Rolling boulders uphill A lot of preclinical projects don't even get off the ground, and many that do still never deliver anything to the development groups. mark for My Articles similar articles
Chemistry World
August 30, 2009
Phillip Broadwith
C-H oxidation proves its worth US researchers are going against the grain of total synthesis and developing new approaches to complex molecules. mark for My Articles similar articles
Chemistry World
June 5, 2015
A prescription for chemists The Public attitudes to chemistry survey revealed that many people confuse chemists with pharmacists. mark for My Articles similar articles
Chemistry World
March 21, 2007
Alison Stoddart
Synthesis Strategy Offers no Protection A radically different approach to constructing complex molecules could help to tap the pharmaceutical potential of natural products. mark for My Articles similar articles
Chemistry World
April 11, 2014
The sultan of synthesis Phil Baran is spurring organic chemists to rethink how they make complex compounds, as Mark Peplow discovers mark for My Articles similar articles
Chemistry World
October 12, 2015
Emma Stoye
Chemistry Nobel laureate Richard Heck dies Richard Heck, the organic chemist who shared the 2010 chemistry Nobel prize with for developing palladium-catalyzed cross coupling reactions, has died aged 84. mark for My Articles similar articles
Chemistry World
January 19, 2010
Simon Hadlington
New 'click' reaction to modify proteins Chemists in the US have discovered a new way to attach small molecules to proteins and peptides under mild, aqueous reaction conditions. mark for My Articles similar articles
Chemistry World
June 2008
Sarah Houlton
Breaking the rules The author finds out about some chemical tricks that can give a new drug the best possible odds of success mark for My Articles similar articles
Chemistry World
December 13, 2009
Lewis Brindley
Breaking the strongest bonds Chemists have uncovered a way to sever two of the strongest bonds in chemistry - in dinitrogen and carbon monoxide - and make useful organic compounds. mark for My Articles similar articles
Chemistry World
July 9, 2012
Phillip Broadwith
'Molecular cobra' turns C-H to C=C A reagent developed by US chemists can selectively introduce synthetically useful C=C double bonds into unactivated carbon chains, guided by an activating group attached to a nearby oxygen or nitrogen atom. mark for My Articles similar articles
Chemistry World
March 2012
Lead-oriented synthesis Ian Churcher and Alan Nadin call for the development of more robust synthetic tools to improve small molecule survival rates in the perilous journey from lead to drug mark for My Articles similar articles
Chemistry World
September 1, 2013
Bibiana Campos Seijo
Chemistry - The next generation What does the future hold for the chemists of tomorrow, those clutching new qualifications and those still coming through the ranks in school? Can chemistry attract a complete cross-section of society? mark for My Articles similar articles
Chemistry World
May 25, 2007
Richard Van Noorden
Keeping it Green Some chemistry enthusiastically labeled as green may be nothing of the kind, warn researchers who worry that mediocre -- if well-meaning -- science is damaging their subject. mark for My Articles similar articles
Chemistry World
June 19, 2008
Hepeng Jia
Chemistry dominates list of China's most influential papers The Thomson Reuters Research Fronts Award recognized a total of 24 key journal articles - including seven chemistry papers and two from the material sciences - for their outstanding contribution to international R&D. mark for My Articles similar articles
Chemistry World
January 6, 2010
Phillip Broadwith
Enzymes do the twist The way enzyme catalysts bind molecules to speed up their reactions is not as simple as once thought, say chemists from the UK and Spain. mark for My Articles similar articles
Chemistry World
March 19, 2009
Manisha Lalloo
Copper catalysts give meta aromatics UK Researchers have discovered that, simply by using a copper catalyst, they are able to perform tricky substitution reactions at a difficult position on benzene rings mark for My Articles similar articles
Chemistry World
February 4, 2011
Elinor Richards
Strychnine in just six steps Strychnine, best known as a poison but also used medicinally as a stimulant, can now be synthesised in just six steps, say US scientists. mark for My Articles similar articles
Chemistry World
January 22, 2014
Eleanor Merritt
Designer esters for complex carbohydrates Scientists based in the US have developed a new strategy to simplify the chemical synthesis of complex carbohydrates. mark for My Articles similar articles
Chemistry World
August 16, 2011
Patrick Walter
Chemists Vent Anger at Funding Body in Letters to UK Government UK chemists are in open revolt over administrative interference in their field by the main grant funder. mark for My Articles similar articles
Reactive Reports
Issue 60
David Bradley
Mark Leach Interview with the owner of Meta-Synthesis, a company aimed to reveal the inner secrets of chemistry to as wide an audience as possible. mark for My Articles similar articles
Chemistry World
October 19, 2007
Richard Van Noorden
Building Tomorrow's Nanofactory UK scientists have been granted 2.5 million pounds to invent a nanomachine that can build materials molecule by molecule. Such a robot doesn't -- and may never -- exist, though it has been imagined for over half a century. mark for My Articles similar articles
Chemistry World
July 6, 2012
Protein power Tom Muir, professor of chemistry and molecular biology, Princeton University, US, is an expert in protein engineering and its application to studying cellular signalling networks. mark for My Articles similar articles