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Chemistry World
November 2010
Carbon Couplers Take the Prize Three giants of organic chemistry, who pioneered palladium-catalysed cross coupling reactions, have shared this year's Nobel prize. mark for My Articles similar articles
Chemistry World
October 6, 2010
Simon Hadlington
Trio share Nobel for palladium-catalysed cross-coupling Richard Heck of the University of Delaware in Newark, US, Ei-ichi Negishi of Purdue University, US, and Akira Suzuki of Hokkaido University in Japan, independently developed palladium-catalysed cross-coupling reactions as a way to forge new carbon-carbon bonds with precision mark for My Articles similar articles
Chemistry World
February 6, 2011
Laura Howes
Cells as test tubes Chemists have used living cells as test tubes to carry out chemical reactions never before seen within living cells. mark for My Articles similar articles
Chemistry World
May 24, 2007
James Mitchell Crow
Palladium Coupling in Fewer Steps Look out Suzuki - Canadian chemists have successfully joined up simple benzene ring-like aromatics without any pre-activation. mark for My Articles similar articles
Chemistry World
August 16, 2009
Tom Bond
Catalyst free carbon-carbon bond formation The method offers an environmentally friendly way to form one of the most important bonds in organic synthesis. mark for My Articles similar articles
Chemistry World
October 2009
Column: In the pipeline Derek Lowe discusses the problem of leaning too heavily on favorite reactions mark for My Articles similar articles
Chemistry World
April 12, 2012
Simon Hadlington
Recruiting electrophiles for organic cross-coupling Chemists in the US have taken an unconventional approach to carbon cross-coupling and in doing so have potentially opened the door to the rapid and efficient synthesis of a wide range of organic compounds. mark for My Articles similar articles
Chemistry World
June 2007
Dylan Stiles
Opinion: Bench Monkey This PhD student takes an organic chemist's tour around the periodic table. mark for My Articles similar articles
Chemistry World
June 21, 2012
Laura Howes
Chemistry nobel laureate William Knowles dies Knowles shared the Nobel prize in Chemistry in 2001 with Ryoji Noyori and Barry Sharpless, for their work in asymmetric catalysis. Noyori and Knowles shared half the prize for their work on asymmetric hydrogenation reactions. mark for My Articles similar articles
Chemistry World
August 2008
Column: In the pipeline Problems develop when there are too few workhorse reactions, which may well generate compounds that are too similar to each other. Are we at that stage now? mark for My Articles similar articles
Chemistry World
June 24, 2010
Phillip Broadwith
Aryl rings get a fluorine fix A mild and effective method for coupling trifluoromethyl groups on to aryl rings has been developed by US chemists. mark for My Articles similar articles
Chemistry World
August 11, 2010
Simon Hadlington
Non-metal-catalysed C-C coupling Chinese chemists have successfully coupled aromatic molecules without the use of a transition metal catalyst - something that people have been trying to do for years with little success. mark for My Articles similar articles
Chemistry World
August 22, 2014
Derek Lowe
Death of a reagent Anyone who's been practicing organic chemistry for a while can think back to reactions and reagents that were once in far wider use than they are today. mark for My Articles similar articles
Chemistry World
January 25, 2013
Derek Lowe
Name reactions: how does the label stick? Some of these names go back to the 19th century, and many more of them come from the first decades of the 20th. Once in a while, I wonder if the tradition is dying out. Are we still naming chemical reactions after their discoverers? mark for My Articles similar articles
Chemistry World
March 20, 2008
James Mitchell Crow
Surfactants Help Reactions Work in Water Scientists have discovered a surfactant that allows the catalytic organic reactions commonly used to assemble organic structures such as drug molecules to be run in water. mark for My Articles similar articles
Chemistry World
April 7, 2015
Hugh Cowley
The Goldilocks of heterogeneous catalysis An international team of scientists has tethered palladium to a metal -- organic framework support using thiol groups normally associated with catalyst poisoning mark for My Articles similar articles
Chemistry World
July 17, 2014
Karl Collins
Organic chemistry: a mechanistic approach Aimed at undergraduate chemistry students, this relatively succinct text begins with the fundamentals of molecular structure and introduces the concept of molecular orbitals early. mark for My Articles similar articles
Chemistry World
June 1, 2012
Mike Sutton
A reluctant chemist A century after Francois Auguste Victor Grignard's Nobel prize, organic chemists are still using the reagents he developed. mark for My Articles similar articles
Chemistry World
May 8, 2012
Phillip Broadwith
Keep stirring that Suzuki The shape of your reaction vessel can influence the behavior of organotrifluoroborate compounds in Suzuki cross-coupling reactions, say chemists in the UK. mark for My Articles similar articles
Chemistry World
November 2007
Book Reviews A review of books on: good clinical & laboratory practices, green chemistry, environmental chemistry, organic reactions in water, universal asymmetry, and molecular models for fluids. mark for My Articles similar articles
Reactive Reports
December 2006
David Bradley
Dick Wife An interview with the chemical IT scientist and co-founder of SORD, a scientific publishing company that seeks to solve the problem of organizing the myriad of undocumented chemistry and the chaotic mess of the commercial database. mark for My Articles similar articles
Chemistry World
December 18, 2013
Emma Stoye
Chemistry Nobel winner John Cornforth dies Sir John Cornforth, joint winner of the 1975 Nobel prize in chemistry, has died aged 96. He is best known for his work on the stereochemistry of enzyme-catalyzed reactions, including the biosynthesis of cholesterol. mark for My Articles similar articles
Chemistry World
March 19, 2009
Manisha Lalloo
Copper catalysts give meta aromatics UK Researchers have discovered that, simply by using a copper catalyst, they are able to perform tricky substitution reactions at a difficult position on benzene rings mark for My Articles similar articles
Chemistry World
June 8, 2014
David Bradley
Carbon--carbon couplings go 3D Chemists have devised a new stereospecific coupling reaction for electron-rich aromatics using secondary and tertiary boronic esters that works under mild conditions. mark for My Articles similar articles
Chemistry World
April 10, 2008
Mark Peplow
'Pot-in-a-Pot' Technique Makes Impossible Cascade Reactions Easy A simple technique that nests a series of reaction vessels could help chemists avoid the tedium and expense of purifying organic compounds after each step of a long synthesis. mark for My Articles similar articles
Chemistry World
April 29, 2015
Emma Stoye
Wieland's chemistry Nobel to be sold at auction The chemistry Nobel prize awarded to German chemist Heinrich Wieland in 1927 has been put up for auction at Nate D Sanders in Los Angeles, US, with a starting price of $325,000. mark for My Articles similar articles
Chemistry World
July 9, 2012
Phillip Broadwith
'Molecular cobra' turns C-H to C=C A reagent developed by US chemists can selectively introduce synthetically useful C=C double bonds into unactivated carbon chains, guided by an activating group attached to a nearby oxygen or nitrogen atom. mark for My Articles similar articles
Chemistry World
September 18, 2015
Tim Wogan
Shining a light on amine synthesis A new method for site selective amination of aromatic organic compounds has been developed by researchers in the US. mark for My Articles similar articles
Chemistry World
September 26, 2012
Derek Lowe
Under pressure Someone interviewing for a synthetic chemistry position had better know his or her organic chemistry. It's fair to ask questions that will make sure of that. But does a candidate need to know the curly-arrow details of reactions that they'll never run? mark for My Articles similar articles
Chemistry World
June 7, 2009
Phillip Broadwith
Pd(III) catalysis insight The discovery of a bimetallic palladium(III) complex that can catalyse the formation of carbon-heteroatom bonds adds a new facet to our understanding of the chemistry of one of the most widely-used metals in catalysis, say US chemists. mark for My Articles similar articles
Chemistry World
November 25, 2014
James Urquhart
Nanomolar chemistry enables 1500 experiments in a single day Chemists have conducted over 1500 chemistry experiments in under a day thanks to a miniaturized, high throughput automation platform they developed for identifying how synthetic molecules react under various conditions. mark for My Articles similar articles
Chemistry World
March 22, 2012
Ross McLaren
Back to the future: old reactions to help the new Researchers from the US have delved into the history of organic chemistry to help chemists better predict the effect that functional groups will have on one another within a molecule. mark for My Articles similar articles
Chemistry World
April 25, 2014
Derek Lowe
Engineering serendipity At this stage in the world of organic chemistry, you'd have to think that many of the great reactions that can be stumbled across with known reagents have probably been found. mark for My Articles similar articles
Chemistry World
June 19, 2013
John Hayward
Science of synthesis workbench edition: water in organic synthesis If a chemist is looking to do chemistry in (or on) water at the bench, Water in organic synthesis by Shu Kobayashi will be their guide. mark for My Articles similar articles
Chemistry World
May 22, 2015
James Urquhart
Complex amines made easy (and cheap) Phil Baran's lab at the Scripps Research Institute, La Jolla, has come up with a protocol that repurposes two readily available and inexpensive feedstock building blocks; olefins and nitroarenes, via iron-catalysed cross-coupling. mark for My Articles similar articles
Chemistry World
May 29, 2015
Derek Lowe
Magic molecule modifiers The synthesis of a new organic molecule can be approached in several ways. mark for My Articles similar articles
Chemistry World
November 2007
Derek Lowe
Column: In the Pipeline Chemists are finally going with the flow. mark for My Articles similar articles
Chemistry World
November 3, 2008
Simon Hadlington
Organic synthesis set for auto-pilot Peptides are routinely made by machines that couple together amino acid components. Could organic synthesis ever get this simple? mark for My Articles similar articles
Chemistry World
September 20, 2007
Lewis Brindley
New Catalyst Rings the Changes Organic chemists in the US have developed a method to control the stereochemistry of a useful intramolecular Diels-Alder reaction. mark for My Articles similar articles
Chemistry World
June 2011
Column: Totally Synthetic I've never heard of the Polonovski-Potier reaction, the keystone of a remarkable synthesis by a team led by Tohru Fukuyama at the University of Tokyo, Japan. mark for My Articles similar articles
Chemistry World
February 2, 2011
Elinor Richards
Gold going it alone Spanish scientists have proved that gold alone can catalyse cross-coupling reactions following a claim made last year that palladium impurities in the gold are essential for the catalysis. mark for My Articles similar articles
Chemistry World
April 30, 2015
Rebecca Trager
Anton Toutov: The power of potassium Toutov says the potassium catalyst he has developed costs only about $30 per mole, or less. 'It is safer and non-toxic, and a lot more cost-effective,' he states. mark for My Articles similar articles
Chemistry World
July 1, 2012
Paul Docherty
Vincorine Cage-structured natural products are some of the most appealing (if perhaps not appetising) targets for organic chemists -- perhaps due to their obvious intricacy of form, but also because of their structural rigidity. mark for My Articles similar articles
Chemistry World
March 20, 2007
Tom Westgate
Is Your Lab Ready to go Veggie? In a recently published review article, Geoffrey Cordell demonstrates that the greengrocer's could be an unexpected goldmine of sustainable, cheap reagents that would benefit chemistry in developing countries. mark for My Articles similar articles
Chemistry World
March 2006
Flashback 60 Years Ago: US chemist Gilbert Newton Lewis died... 90 Years Ago: Christian Boehmer Anfinsen was born in Pennsylvania... 95 Years Ago: Jacobus Henricus van't Hoff died... etc. mark for My Articles similar articles
Chemistry World
October 12, 2011
Joanne Thomson
Hot Chemistry Temperature played a crucial role in David MacMillan's decision to study chemistry. mark for My Articles similar articles
Chemistry World
September 4, 2008
Fred Campbell
Two catalysts better than one US researchers have cracked a long standing problem in chemical synthesis - the catalytic alpha-alkylation of aldehydes - by combining two catalysts in one pot. mark for My Articles similar articles
Chemistry World
December 13, 2009
Lewis Brindley
Breaking the strongest bonds Chemists have uncovered a way to sever two of the strongest bonds in chemistry - in dinitrogen and carbon monoxide - and make useful organic compounds. mark for My Articles similar articles
Chemistry World
September 9, 2011
James Mitchell Crow
High-throughput catalyst screening for the masses Using nothing more than the standard chemistry lab equipment, researchers in the US have successfully turned the discovery of new catalytic reactions into a high-throughput process. mark for My Articles similar articles
Chemistry World
November 1, 2012
Laura Howes
Shining new light on the Ullmann reaction Ullmann C -- N coupling -- a copper mediated carbon -- nitrogen coupling reaction used to create arylamines -- is one of the most widely used reactions in the pharmaceutical industry. mark for My Articles similar articles