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IEEE Spectrum
March 2011
Lucks & Arkin
Synthetic Biology's Hunt for the Genetic Transistor How genetic circuits will unlock the true potential of bioengineering mark for My Articles similar articles
HHMI Bulletin
February 2011
Mitzi Baker
When Worlds Collide The right time and place led to a new RNAi-like pathway in bacteria for biochemist Jennifer Doudna and geobiologist Jill Banfield. mark for My Articles similar articles
HHMI Bulletin
February 2011
Michele Solis
Right Before Your Eyes Coupling protein sequence to function, thousands of variants at a time. mark for My Articles similar articles
Bio-IT World
March 8, 2005
Kevin Davies
Evolution of New Genes Studied EMBL researchers use comparative genomic analysis to identify new primate-specific gene family. mark for My Articles similar articles
Scientific American
June 2005
JR Minkel
RNA to the Rescue The spectacular discovery that a species of plant can summon up genes its parents have lost highlights biologists' increasing recognition of RNA as a more versatile and important molecule in its own right. mark for My Articles similar articles
Scientific American
July 2008
Christine Soares
Looking at Yesterday's Genes for Tomorrow's Cures Resurrected "jumping gene" could deliver DNA. mark for My Articles similar articles
Chemistry World
November 16, 2006
Simon Hadlington
Gene-Reading Enzyme Catapulted by Scrunch Power Two teams of researchers have solved a conundrum that has baffled molecular biologists for 20 years -- how the enzyme responsible for `reading' genes can release itself from the portion of DNA to which it initially binds extremely tightly. mark for My Articles similar articles
Chemistry World
April 20, 2009
James Urquhart
New method reveals small molecule-RNA conjugates US scientists using novel chemical screening methods have discovered a new class of small molecules connected to RNA, suggesting that cellular RNA may be more chemically diverse than previously thought. mark for My Articles similar articles
Chemistry World
March 15, 2007
Henry Nicholls
The Mother of All Enzymes Scientists have uncovered the three-dimensional structure of what might be biology's first enzyme. This sheds light on the chemistry at a key moment in the origin of life, they argue. mark for My Articles similar articles
Managed Care
November 2003
Thomas Morrow
Making Sense of Antisense and Interference Treatments that interfere with protein synthesis at the cellular level will soon be debated in medical policy committee meetings. mark for My Articles similar articles
Chemistry World
February 2012
Column: The crucible To understand the chemical choreography of the cell, we must acknowledge the bustling biomolecular ballroom in which it takes place, says Philip Ball mark for My Articles similar articles
Chemistry World
April 19, 2012
Andy Extance
Polymers perform non-DNA evolution Scientists have found that six polymer alternatives to DNA can pass on genetic information, and have evolved one type to specifically bind target molecules. mark for My Articles similar articles
HHMI Bulletin
Winter 2013
Sarah C.P. Williams
Cellular Search Engine Craig Mello's lab has now uncovered the reason piRNA molecules are so ubiquitous and exist in so many forms in C. elegans: so they can pair with essentially any genetic sequence they encounter during their endless scanning. mark for My Articles similar articles
Chemistry World
February 18, 2008
John Bonner
Flicking the Acetyl Switch A strain of Escherichia coli that can produce proteins containing an acetylated version of the amino acid lysine could help to reveal how acetylation changes the function of hundreds of proteins inside cells. mark for My Articles similar articles
HHMI Bulletin
May 2011
Sarah C.P. Williams
The Pace of Evolution A close look at the human genome shows the slow and steady beat of adaptation. mark for My Articles similar articles
Wired
January 2005
Oliver Morton
Life, Reinvented A group of MIT engineers wanted to model the biological world. But, damn, some of nature's designs were complicated! So they started rebuilding from the ground up - and gave birth to synthetic biology. mark for My Articles similar articles
Chemistry World
December 12, 2006
Michael Gross
Ancient Protein Moonlights in the Eye A structural protein in the mouse eye lens is the evolutionary descendant of an ancient bacterial enzyme, researchers have found -- suggesting that moonlighting saved the protein from oblivion when its original role was taken over by a different family of enzymes. mark for My Articles similar articles
Chemistry World
April 7, 2011
Laura Howes
Long chains give new life to RNA world hypothesis The so-called RNA world hypothesis has gained fresh momentum with the synthesis of the longest lab grown RNA strands made using an enzyme that is itself made of RNA, an 'RNAzyme'. mark for My Articles similar articles
Chemistry World
June 30, 2011
Laura Howes
Chemically evolved bacteria European scientists have created an Escherichia coli strain with a separate genome using chlorinated DNA. mark for My Articles similar articles
Chemistry World
January 11, 2008
John Bonner
DNA Nanoparticles Detect Gene Expression US scientists have made nanoparticles from DNA that they say could be used to identify the genes being expressed in a single cell. mark for My Articles similar articles
Chemistry World
October 1, 2008
Hayley Birch
Chemical Knockout for Chlamydia US scientists have used chemical inhibitors to block proteins that Chlamydia produces as it invades cells. mark for My Articles similar articles
Bio-IT World
February 11, 2005
Kevin Davies
Bioinformatics on the Brain Adaptive selection: accelerated mutation rate produced humans' large brain. mark for My Articles similar articles
Scientific American
March 2009
W. Wayt Gibbs
Evolution in a Bottle: Synthetic Life Oozes Closer to Reality Self-replicating RNAs advance science another step toward artificial life mark for My Articles similar articles
Bio-IT World
April 15, 2003
Malorye Branca
Beyond the Blueprint How will the wealth of data emanating from the human genome and allied technologies impact research on health and disease? mark for My Articles similar articles
Chemistry World
August 8, 2012
Protein Coat for Gene Therapy Kenneth Woycechowsky's group at the University of Utah has modified a non-viral protein so that it will carry RNA. mark for My Articles similar articles
Salon.com
December 19, 2000
Carolyn McConnell
"The Century of the Gene" by Evelyn Fox Keller A new book argues that there may be no such thing as a gene. At least, it has proved very difficult to isolate a discrete physical item that can do the work our notion of the gene does... mark for My Articles similar articles
Chemistry World
June 9, 2008
Simon Hadlington
Artificial virus silences genes Scientists in Korea have created an artificial virus that can target the nucleus of cancer cells and knock out specific genes. mark for My Articles similar articles
Chemistry World
January 12, 2015
Emma Stoye
Protein mutant libraries to probe diseases' genetic link quickly and cheaply Researchers in the US have developed a faster and less costly way to investigate the effects of genetic mutations on proteins, which should offer new insights into hereditary diseases. mark for My Articles similar articles
Chemistry World
January 8, 2012
David Bradley
The TNA world that came before the RNA one Once it was recognised that DNA is key to the molecular self-replication that underpins life, chemists have sought to understand the origins of this double-helical molecule in that primordial age. mark for My Articles similar articles
Chemistry World
September 9, 2007
Simon Hadlington
Sugaring the Pill Researchers in the US have made a key advance in efforts to bolt sugar molecules onto natural products in the search for new drugs. mark for My Articles similar articles
Chemistry World
January 20, 2011
Hayley Birch
Programmable RNA promising for bio-compatible therapies Programmable nanostructures based on ribonucleic acid could be used as vessels for shipping therapeutic molecules into cells, according to US scientists. mark for My Articles similar articles
Technology Research News
January 1, 2003
Eric Smalley
Altered protein orders metal bits Researchers from NASA, the SETI Institute and Argonne National Laboratory have genetically modified a bacteria that lives in geothermal hot springs in order to make a microscopic scaffolding that produces a high-tech material. mark for My Articles similar articles
HHMI Bulletin
May 2010
Robert Tjian
Biomolecular Crowdsourcing A generation of web-savvy entrepreneurs has found a relatively cheap and effective approach to solving complex problems and soliciting ideas: toss out a challenge into a vibrant digital community and watch what happens. mark for My Articles similar articles
Chemistry World
June 21, 2007
Simon Hadlington
Boron is Key to Antifungal Agent Researchers have shown that the presence of a boron atom is key to an antifungal agent being developed to treat infections of fingernails and toenails. mark for My Articles similar articles
Chemistry World
July 17, 2012
Simon Perks
Synthetic nanozymes silence hepatitis C Researchers at the University of Florida, US, have discovered that an artificial nanoparticle complex, known as a nanozyme, can help to treat viral infections by 'shutting off' their genetic material. mark for My Articles similar articles
HHMI Bulletin
February 2011
Crucibles of Dynamism Puzzling pockets of redundancy account for about 5 percent of the human genome. Investigator Evan Eichler found a way to interpret what is happening in these areas of genetic repetition. mark for My Articles similar articles
HHMI Bulletin
February 2012
Sarah C. P. Williams
Force Factor In the context of cells, forces are required to move molecules. Quantifying these forces gives scientists a way to compare and contrast different molecular motors. mark for My Articles similar articles
CIO
May 1, 2003
John Edwards
Bubbling Up Nanostructures Nearly boiling, acidic hot springs could lead to the creation of electronic components that are 10 to 100 times smaller than today's smallest parts. mark for My Articles similar articles
Chemistry World
November 2006
Bea Perks
Call That Chemistry? This year's Nobel prize in chemistry was a tour de force for crystallography, underscoring the vital role chemistry plays across the sciences. mark for My Articles similar articles
HHMI Bulletin
Nov 2011
Nicole Kresge
Bacterial -- Viral Warfare with CSF When bacteria survive a run-in with a virus or phage, they take some of the invader's DNA and integrate it into their own genome to help combat future attacks. mark for My Articles similar articles
Chemistry World
December 21, 2006
Henry Nicholls
Silent SNPs Serve up a Structural Surprise The sequence of amino acids no longer dictates the structure and function of a protein according to a surprising new paper. mark for My Articles similar articles
Chemistry World
October 2, 2006
Bea Perks
RNAi Pioneers Win Nobel Prize for Medicine Molecular biologists Andrew Fire and Craig Mello have been awarded this year's Nobel prize in physiology or medicine for their discovery of RNA interference. mark for My Articles similar articles
Technology Research News
March 24, 2004
DNA has nano building in hand Researchers from Ludwig Maximilians University in Germany have built a simple molecular machine from DNA that can bind to and release single molecules of a specific type of protein. mark for My Articles similar articles
Fast Company
November 2009
David H. Freedman
The Gene Bubble: Why We Still Aren't Disease-Free When the human genome was first sequenced nearly a decade ago, the world lit up with talk about how new gene-specific drugs would help us cheat death. Well, the verdict is in: Keep eating those greens. mark for My Articles similar articles
Chemistry World
August 29, 2007
Ananyo Bhattacharya
'Lost' Folate Enzyme Found After 30 Years US researchers have revealed the identity of an enzyme used by bacteria to make the essential B vitamin folate, 30 years after it was first isolated. mark for My Articles similar articles
Chemistry World
July 23, 2012
Melissae Fellet
RNA wrapper protects small molecules Step aside benzene rings, there's a new protecting group in town. Dutch researchers have used a strand of RNA to cover portions of a complex small molecule. They then chemically modified a portion of the molecule not covered by the RNA. mark for My Articles similar articles
Bio-IT World
April 15, 2003
Robert M. Frederickson
Protein Chemistry Surfaces Protein chips seek to do for protein expression profiling what DNA chips did for RNA expression. mark for My Articles similar articles
Technology Research News
June 16, 2004
Genes Automate DNA Machines Researchers have taken a step toward automating nanomachines with a method that allows instructions for a DNA-based machine to be contained in a gene, or another stretch of DNA. mark for My Articles similar articles
Chemistry World
June 23, 2015
Derek Lowe
Missing the target There are enzymes that no mustard has ever cut, to steal a phrase from science fiction author James Blish. Phosphatases, the flip side of kinase activity, are a perfect example. mark for My Articles similar articles
Chemistry World
November 27, 2013
Jennifer Newton
A cytochrome from scratch Artificial proteins could be closer to participating in natural biochemical pathways after researchers show that bacteria will process amino acid sequences entirely unrelated to any natural protein to produce a fully functioning cytochrome. mark for My Articles similar articles