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Reactive Reports David Bradley	Integrated Biochips A new microfluidic device that can perform sample preparation, polymerase chain reaction, and microarray detection functions on a single device has been developed by US researchers.
Chemistry World August 19, 2009 Hayley Birch	Gold nanoparticles detect cancer Chinese scientists have used gold nanoparticles as ultrasensitive fluorescent probes to detect cancer biomarkers in human blood.
Chemistry World April 25, 2007 Victoria Gill	Nanoscale Scales Scientists at MIT have designed a device able to accurately weigh single nanoparticles within a liquid. The new technique is based on the ultra-sensitive mass detection made possible by nanomechanical resonators.
Chemistry World September 8, 2014 Emma Stoye	CPU heat powers PCR disease detection Scientists in the US have devised a new way of carrying out blood tests -- based on a modified computer and camera phone -- that could lower the costs of disease screening in developing countries.
Chemistry World June 13, 2012 Elinor Hughes	Paper and plastic HIV test A DNA test to detect HIV in infants in resource-poor countries is a step closer, thanks to a technique to amplify DNA samples developed by US scientists.
Chemistry World June 27, 2010 Simon Hadlington	Nanoparticles allow remote control of cells In an experiment reminiscent of the mind-control rays that featured prominently in B-movies from the 1950s, scientists in the US have used a magnetic field to alter the behavior of an animal.
Chemistry World April 13, 2011 Kate McAlpine	Microrockets aim at cancer diagnostics Researchers at the University of California, San Diego, have made self-propelled microtube rockets that can find and capture cancer cells from blood samples.
Chemistry World March 30, 2012 Russell Johnson	Miniaturizing disease diagnosis tool South Korean scientists have created a temperature cycle for the on-chip flow-through polymerase chain reaction using a single heater.
Chemistry World April 7, 2009 Lewis Brindley	Cells get in line Magnetic nanoparticles that 'shepherd' cells into neat lines have been designed by American scientists.
Chemistry World November 27, 2007 James Mitchell Crow	A Flare for Gene Silencing US scientists have developed nanoparticle probes coated with DNA that release fluorescent 'flares' when they silence genes inside cells.
Scientific American March 2009 Elaine Schattner	A Chip against Cancer: Microfluidics Scrutinizes T Cells With just a blood sample, a device could determine whether cancer is about to spread or monitor the progress of treatment
Chemistry World May 4, 2010 Lewis Brindley	Blood type testing for a few pence 'Our technique prints a microfluidic circuit containing the three antibodies (A, B and D) directly onto paper,' says Gil Garnier, who led the research at Monash University in Melbourne.
Chemistry World March 19, 2007 Jessica Ebert	Pocket-Sized PCR Machine Scientists in the US report being one step closer to designing a miniaturized, portable polymerase chain reaction machine that could be used for applications such as point-of-care diagnostics.
Chemistry World March 11, 2011 Elinor Richards	Making baby food safer Scientists from Spain have used a lab on a chip device to quickly analyse levels of zearalenone, a contaminant, in infant foods with a detection limit below legislative requirements.
Chemistry World May 1, 2007 Jessica Ebert	Pocket-sized PCR Machine Scientists in the U.S. report being one step closer to designing a miniaturized, portable PCR machine that could be used for applications such as point-of-care diagnostics.
Chemistry World June 2, 2015 Tim Wogan	Simple sensor can spot cancer markers in minutes An electrochemical sensor that can detect specific mutant nucleic acids from cancers in blood samples could allow quick and cheap 'liquid biopsies'.
Chemistry World February 13, 2006	Nanoparticles Detect Cell Suicide Plans Researchers have developed a nanotechnological assay for detecting programmed cell death. The technique is effective in cell cultures, they report, and might eventually be used in humans.
Chemistry World July 22, 2013 Kirsty Muirhead	Circulating cancer cells spiral towards separation A new biochip developed by researchers in Singapore can isolate tumor cells from blood samples, and may one day be an alternative to more invasive methods for tracking later stage cancers.
Technology Research News February 25, 2004 Eric Smalley	Biochip makes droplet test tubes Researchers who are developing biochips are taking two distinct approaches in devising ways to shunt tiny amounts of liquids around. One focuses on finding ways to form microscopic channels and tiny mechanical pumps. The other is aimed at using electricity to maneuver tiny droplets on surfaces.
Chemistry World February 6, 2008 Simon Hadlington	Better Detection of DNA Synthesis Researchers in the US have developed a new way to detect DNA synthesis in living cells by using click chemistry -- the concept of reacting together two 'high energy' molecules that 'click' together efficiently under mild conditions.
Chemistry World July 25, 2013 Rowan Frame	Nanomagnets clean blood Nanoparticles that never have to enter the body can capture harmful components in blood, scientists in Switzerland have shown.
Bio-IT World October 14, 2004 Robert M. Frederickson	Nanosphere Strikes Gold Recently, scientists at Nanosphere developed a colorimetric method for DNA detection that obviates the need for target or signal amplification.
Chemistry World July 16, 2009 Lewis Brindley	Sound waves speed up sexual assault testing Separating the male and female components of sexual assault evidence using sound waves could vastly cut the time it takes to identify suspects, researchers in the US and Sweden report.
Chemistry World October 24, 2012	Less is more for DNA reactions A technique allowing the use of small amounts of DNA for efficient DNA-directed chemistry has been developed by scientists in Germany.
Chemistry World January 26, 2011 Anna Watson	Channelling deeper to target breast cancer US scientists have developed a model of the breast ductal system that could be used to discover abnormal cells or deliver drugs at locations further along the ducts than other techniques. The model fits on a slide, enabling on-chip experiments.
Chemistry World May 5, 2011 Simon Hadlington	Revolutionary new single-cell labelling method Researchers in the US and Canada have combined mass spectrometry with a technique called flow cytometry to follow dozens of biochemical markers on individual cells simultaneously.
Chemistry World August 15, 2007 John Bonner	Chemists Claim Biological Alchemy South Korean chemists say they have turned muscle cells from the sole of a human foot into something akin to stem cells, using a simple molecule called neurodazine.
Chemistry World January 17, 2014 Katia Moskvitch	Life may have begun in a tiny water droplet Chemical reactions run much faster and more efficiently when they take place in tiny droplets rather than in freestanding water -- such as a puddle or a lake, say researchers.
IEEE Spectrum March 2010 Prachi Patel	A World-beating TB Detector To quickly and cheaply diagnose the world's worst infectious disease, engineers have shrunk an NMR machine down to size
Chemistry World October 7, 2012 David Bradley	Magnetic nanoparticles zap cancer Nanoparticles can be used as a remote-controlled magnetic death switch to kill cancer cells, according to researchers from Korea.
Chemistry World March 12, 2012 Francesca Burgoyne	Genetic testing? We've got an app for that US scientists have developed a device dubbed Gene-Z for point-of-care genetic testing using a smartphone interface that has realistic commercial potential.
Managed Care January 2006 Thomas Morrow	Four-Color Flow Cytometry Detects Minimal Residual Disease in Leukemia Should a new - and cheap - test for chronic lymphocytic leukemia be a component of prior-authorization protocols?
Chemistry World November 27, 2014 Megan Tyler	Femtofluidic droplet manipulation now possible We've had microfluidics. We've even had nanofluidics. But now, scientists have gone a step smaller by pushing femtofluidics into the realms of possibility.
Chemistry World March 2011	60 years of innovation To celebrate the international year of chemistry, James Mitchell Crow looks back at some of the discoveries and developments made by chemists over the past six decades
Chemistry World October 2, 2012 Fiona McKenzie	Protein sorting within cells US scientists have used magnetic nanoparticles with specific ligands to latch on to and visualize specific proteins in living cells.
Chemistry World March 30, 2009 Ned Stafford	Moving forward: self-propelling oil droplets In the latest step toward creation of artificial living cells in a laboratory, a team of Japanese researchers has developed a new variety of oil droplets that propel themselves through an aqueous solution.
Chemistry World February 4, 2011 Harriet Brewerton	Transplant tracking Magnetic nanoparticles could be used to track neural stem cells after a transplant in order to monitor how the cells heal spinal injuries, say UK scientists.
Chemistry World November 10, 2006 Victoria Gill	Healing Threads Spun From Living Cells Researchers have successfully made microthreads from polymers containing living cells, using a technique called electrospinning. These biologically active threads could be formed into medical scaffolds, to deliver cells directly to tissue and promote healing.
Chemistry World June 26, 2007 Lionel Milgrom	Mimicking Biophysics with Water Droplets Scientists have micro-engineered water droplets into protocells. Protocell networks can mimic real biophysical events within living cells.
Chemistry World November 1, 2013 Megan Tyler	High-throughput chip for drug screening in 3D A simple micro-array chip developed by scientists in China could sharpen the search for new drugs by enabling the high-throughput screening of drug candidates against cells cultured in three dimensions.
Chemistry World July 30, 2007 James Mitchell Crow	Cell Transplant Hope for Diabetes Sufferers Iron-based 'magnetocapsules' of insulin-producing cells could help doctors use cell transplants to treat type I diabetes.
Chemistry World July 18, 2013 Emma Stoye	Hovering reaction driven by sound Colleagues at ETH Zurich in Switzerland used their acoustic levitator to create an explosive mid-air reaction between a tiny water droplet and a grain of sodium.
Bio-IT World November 14, 2003 Elizabeth Gardner	Ultimate Analysis With the necessary tools at hand, the race is on to build -- and market -- the first affordable, portable, fully functional DNA analyzer. Is the world ready?
HHMI Bulletin May 2010 Sarah C.P. Williams	Young Again Niche cells can reverse the aging of stem cells.
Food Engineering May 1, 2005 Kevin T. Higgins	A better germ-detecting mousetrap A quick test designed for combat soldiers under attack from biological weapons could make life easier for food companies concerned about pathogens in their plants and products.
Scientific American January 2009 Charles Q. Choi	Do White Blood Cells Make Cancer Deadly? The ability to spread underlies the killing power of cancer. The process occurs, John Pawelek thinks, when tumor cells fuse with white blood cells -- an idea that, if right, could yield new therapies
Chemistry World January 15, 2014 Kirsty Muirhead	Biomarkers leave gender clues at crime scene Scientists in the US have unveiled details of a colorimetric assay that could provide an initial indication of a suspect's gender during the on-scene stages of a forensic investigation.
Chemistry World December 6, 2013 Julianne Wyrick	Crowdsourcing unearths promising anticancer compound Crowdsourcing soil from across the US turned up some interesting fungi with promising medicinal molecules.
Chemistry World November 7, 2014 Katrina Kramer	Smartphone delivers rapid blood group test The test is simple enough to be used by non-experts and the smartphone link could help users at remote medical facilities.
Salon.com March 29, 2000 William Speed Weed	Nobel dude Kary Mullis revolutionized genetic research but thumbs his nose at the scientific establishment. It thumbs its nose right back.