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HHMI Bulletin Feb 2012 Mary Bates |
Passing the Sniff Test Researchers are mapping the chemical signaling behind how mice detect friend and foe. |
HHMI Bulletin May 2011 R. John Davenport |
Wired for Smell Circuits of excitation and inhibition help the brain interpret odors. |
HHMI Bulletin February 2011 Sarah C.P. Williams |
Releasing the Brakes on Cell Fate Converting one cell type directly into another is a kind of modern-day alchemy, an ultimate goal in biological research. But unlike turning base metals into gold, changing a cell's identity is feasible, new research shows. |
HHMI Bulletin May 2011 Sarah C.P. Williams |
The Very Hungry Mouse Activating one set of neurons makes a mouse eat, and eat, and eat. |
Chemistry World July 21, 2011 Elinor Richards |
Cell Control to Change Cell Function US scientists can now control the reactions occurring inside cells. |
HHMI Bulletin May 2012 Nicole Kresge |
Locating a Genetic Glitch A team of 41 scientists led by HHMI investigator Louis Ptacek has pinpointed the gene responsible for a rare disease that causes sudden, uncontrollable movements. The culprit is a little known protein that may be responsible for communication between neurons. |
Chemistry World March 21, 2012 Elinor Richards |
Sensor that smells like a dog Scientists in Korea have developed a biosensor for assessing food quality that mimics the way receptors in a canine nose respond to smells. |
HHMI Bulletin Winter 2013 Rabiya Tuma |
Sister Act As a systems neuroscientist, Yang Dan integrates functional studies in animals with computer programs, computational tools, and statistics. |
HHMI Bulletin May 2010 Ivan Arnato |
Light Moves Light is becoming the tool of choice for researchers who want to precisely manipulate neurons and other cells. |
HHMI Bulletin February 2011 Brian Vastag |
Hope Floats With a new arsenal of robust models of ALS, drug development may move to the fast track. |
HHMI Bulletin Winter 2013 Amber Dance |
A Trick of Light When miniSOG protein takes in blue light, it converts ordinary oxygen into a short-lived, excited state called singlet oxygen, which reacts with and changes the molecules around it. The singlet oxygen destroys the mitochondria's delicate machinery. |
HHMI Bulletin Spring 2013 Nicole Kresge |
Itching to Be Discovered When the receptor for capsaicin -- the chemical that gives heat to chili peppers -- is added to itch-sensing neurons, exposure to the normally painful capsaicin causes itchiness. |
Chemistry World March 17, 2009 Phillip Broadwith |
Electronic 'nose' could shed light on sense of smell Korean researchers have combined human smell receptors with nanotechnology to create a new kind of 'bio-electronic nose' |
Chemistry World September 17, 2013 Laura Howes |
Cork taint shuts down your nose 2,4,6-Trichloroanisole is often the compound held responsible for the musty, unpleasant smell of 'corked' wine. |
HHMI Bulletin May 2010 Sarah Goforth |
Scratching the Surface There's nothing funny about an itch that drives you mad. |
HHMI Bulletin February 2012 Nicole Kresge |
Protein Precision in the Brain with CSF Two causes of autism arise from opposite cellular mechanisms. Too much or too little protein production at the synapse between neurons can cause autism and intellectual disability. |
HHMI Bulletin Winter 2013 Megan Scudellari |
Tunneling Out A research team including HHMI investigator Melissa Moore at the University of Massachusetts Medical School has discovered an alternative passageway used by RNA -- protein complexes to exit the nucleus. |
Chemistry World August 2009 Philip Ball |
Column: The crucible Zinc nanoparticles appear to have the ability to make odorants smell stronger and could a give a valuable insight into how olfaction works |
HHMI Bulletin Nov 2010 Sarah C.P. Williams |
Maternal and Paternal Genes Don't Always Have The Same Effect On Offspring The genes you inherited from your mom and those passed along from your dad don't have equal footing when it comes to how they influence your biology. |
HHMI Bulletin February 2011 Sarah C.P. Williams |
Forgetting Fear A compound given at just the right time may make mice forget to be afraid. |
HHMI Bulletin May 2011 Corinna Wu |
Mouse Cam Tracking techniques offer a long-term view into the mouse brain. |
Chemistry World February 24, 2011 Carl Saxton |
Mapping brain networks US scientists have created a model of the ring-shaped networks of neurons in the brain, which could help researchers to understand small changes within diseased brain cells. |
HHMI Bulletin Aug 2011 Jennifer Michalowski |
Memory Cells at the Ready Special neurons give rodents a leg up when facing unfamiliar territory. |
HHMI Bulletin Feb 2012 Paul Muhlrad |
Changing Channels Appetite and other deep-seated desires could be modified by altering brain ion channels, according to research at Janelia Farm. |
Chemistry World June 2, 2006 Jon Evans |
Axons Get Directions Scientists are a step closer to understanding the processes that control the growth and spread of nerve cells, following the discovery of a protein complex that directs the transport of building material to growing axons. |
HHMI Bulletin February 2012 Marc Wortman |
Where Does It Hurt? Researchers are getting to the molecular details of pain's circuitry to answer the question with real specificity. |
HHMI Bulletin Aug 2011 |
Let's Get Small Tim Harris develops tools neuroscientists can use to measure the brain's activity, to give them a quantitative view inside the elaborate structure of the brain. |
Chemistry World July 2006 John Bonner |
Insect Detectives Chemists and biologists are harnessing the powerful sense of smell that insects possess to devise applications from detecting rotten tomatoes to controlling one of the deadliest diseases in Africa. |
Chemistry World October 3, 2007 Lewis Brindley |
Spicing up Pain Relief Scientists in the US have developed an anaesthetic that can completely block pain without causing numbness. The technique uses capsaicin - the active ingredient in chilli peppers - to target only pain-sensing neurons, and not those associated with feeling or movement. |
Chemistry World January 28, 2013 Philip Ball |
Controversial theory of smell given a boost Humans can smell the difference between ordinary and deuterated organic odorant molecules, according to a new study. Provided that a sufficient number of hydrogen atoms in the molecules are replaced by deuterium, their differing smells are relatively easily detected by most people. |
Chemistry World February 11, 2015 Derek Lowe |
The smell of success The sheer variety of smells that we chemists are exposed to is surely one driver of our passion for the subject. |
HHMI Bulletin Winter 2013 Sarah Goforth |
Rational Exuberance Trained as a cardiologist, Robert Lefkowitz is the first to admit that his 39-year research career has been driven by more than a desire to treat coronary disease. He has always had an unshakeable urge to figure things out. |
Chemistry World March 2, 2009 James Urquhart |
Shining a light on neural activity US researchers have developed a new way to activate brain neurons that could lead to less invasive methods of restoring function in damaged nerves and brain tissue. |
Technology Research News March 24, 2004 |
DNA has nano building in hand Researchers from Ludwig Maximilians University in Germany have built a simple molecular machine from DNA that can bind to and release single molecules of a specific type of protein. |
Chemistry World April 5, 2007 Victoria Gill |
Target for Memory-Enhancing Pills Identified Researchers have taken a step towards developing a pill that could improve memory by pinpointing and testing a potential target enzyme in the brain. |
IEEE Spectrum May 2009 Prachi Patel |
Laser Probes for Brain Experiments Laser-activated probes stimulate brain cells better, say scientists |
HHMI Bulletin Fall 2012 Nora Taranto |
Wiring the Brain with CSF Research by HHMI investigator Bernardo Sabatini suggests that self-reinforcing loops of neural activity may drive the development of synapses in the basal ganglia, a region of the brain that uses sensory and social context to direct movement. |
HHMI Bulletin Aug 2010 Janelle Weaver |
Scientists Identify a Gene That Drives Fruit Fly's Thirst Kristin Scott, an HHMI early career scientist at the University of California, Berkeley, has uncovered a gene, called pickpocket 28 (ppk28), that regulates fruit flies' ability to detect water and how much time they spend drinking. |