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Chemistry World March 21, 2012 Elinor Richards |
Sensor that smells like a dog Scientists in Korea have developed a biosensor for assessing food quality that mimics the way receptors in a canine nose respond to smells. |
Chemistry World September 7, 2008 Simon Hadlington |
Coupled proteins to reveal drug hits Researchers in France have successfully attached an 'electrical switch' to a key class of membrane proteins targeted by many drugs. |
Chemistry World August 24, 2009 Phillip Broadwith |
'Chemical nose' sensor sniffs blood protein profile US scientists have developed a sensor system for profiling the protein content of human blood serum without needing individual receptors for each separate protein. |
Chemistry World August 2009 Philip Ball |
Column: The crucible Zinc nanoparticles appear to have the ability to make odorants smell stronger and could a give a valuable insight into how olfaction works |
Chemistry World July 2006 John Bonner |
Insect Detectives Chemists and biologists are harnessing the powerful sense of smell that insects possess to devise applications from detecting rotten tomatoes to controlling one of the deadliest diseases in Africa. |
Chemistry World March 6, 2011 Mike Brown |
Molecules that walk, hop and jump 'Two legged' molecules walk, hop and fly across a receptor surface, according to researchers in the Netherlands and Ireland. The findings could help us understand how viruses and bacteria interact with cell membranes, they say. |
Technology Research News October 20, 2004 Eric Smalley |
Biochip spots single viruses A detector recently built from nanowire transistors can identify individual virus particles in real time in unpurified samples. Labs-on-a-chip based on the device could be used to monitor diseases. |
Chemistry World December 12, 2011 Simon Hadlington |
Zwitterion approach to stabilizing drug proteins Researchers in the US have discovered a new way to stabilize and protect protein molecules without affecting the protein's biological activity. |
Chemistry World July 21, 2011 Elinor Richards |
Cell Control to Change Cell Function US scientists can now control the reactions occurring inside cells. |
Chemistry World February 3, 2010 Simon Hadlington |
New 'hook' for reversibly binding molecules to proteins UK chemists have found a simple new 'hook' that allows molecules to be attached to proteins and later removed, something that is currently difficult to achieve. |
Chemistry World January 28, 2013 Philip Ball |
Controversial theory of smell given a boost Humans can smell the difference between ordinary and deuterated organic odorant molecules, according to a new study. Provided that a sufficient number of hydrogen atoms in the molecules are replaced by deuterium, their differing smells are relatively easily detected by most people. |
Chemistry World November 10, 2008 Hayley Birch |
Nanotube scales challenge mass spectrometers By precisely measuring tiny fluctuations in mass, carbon nanotubes will allow chemists to follow reactions of individual proteins atom by atom, predict Spanish researchers |
HHMI Bulletin Spring 2013 Nicole Kresge |
Use It or Lose It HHMI investigator Catherine Dulac of Harvard University has uncovered a small molecule that plays a big role in the process of tuning olfactory neurons to the environment. |
Chemistry World May 2012 |
Sniffing out explosives Can science compete with the sensitivity of a sniffer dog's nose? Emma Davies finds out |
Chemistry World October 25, 2007 |
Elusive Drug Target Finally Seen Scientists have captured an atomic-scale picture of a receptor protein from a family that is the target of thousands of drugs. |
Chemistry World January 13, 2008 Ananyo Bhattacharya |
Unexpected Effects of Drug Combinations Medicines that use a combination of several drugs can sometimes produce unexpected effects in patients. Now, a team of scientists think they have figured out how that can happen. |
Chemistry World September 2010 |
Repulsive chemistry Simon Hadlington discovers why some people get bitten by more insects than others, and how new chemical deterrents are helping fight them off |
Chemistry World February 12, 2009 Simon Hadlington |
Mystery receptor's binding partner uncovered For decades scientists have puzzled over the role of the sigma-1 receptor, a protein found in almost all mammalian cells, including the nervous system. |
Technology Research News March 23, 2005 |
Nanowires track molecular activity Researchers from Harvard University have found a way to use transistors made from silicon nanowires to gain information about how small molecules bind to proteins. |
Technology Research News June 29, 2005 |
Self-assembly: the natural way to make things In biology, there are a few different ways DNA molecules can be replicated and combined. |
Chemistry World September 17, 2013 Laura Howes |
Cork taint shuts down your nose 2,4,6-Trichloroanisole is often the compound held responsible for the musty, unpleasant smell of 'corked' wine. |
Chemistry World June 23, 2015 Derek Lowe |
Missing the target There are enzymes that no mustard has ever cut, to steal a phrase from science fiction author James Blish. Phosphatases, the flip side of kinase activity, are a perfect example. |
Chemistry World May 6, 2010 Andy Extance |
Nanotube chip creates bioelectronic link A protein coupled with a carbon nanotube has provided a previously unavailable direct biological-to-electronic interface, which its developers hope could lead to brain-controlled prosthetic devices. |
Reactive Reports Issue 32 David Bradley |
Odor sniffers Tracking down smells that even the most sensitive human nose cannot pick up is now possible, thanks to an inexpensive sensor devised by scientists at the University of Bonn. |
Chemistry World October 18, 2012 |
A signal honor The 2012 Nobel prize in chemistry was awarded to Robert Lefkowitz and Brian Kobilka for studies of G-protein-coupled receptors. This article looks at the molecular machinery underpinning cell signaling. |
Chemistry World February 11, 2015 Derek Lowe |
The smell of success The sheer variety of smells that we chemists are exposed to is surely one driver of our passion for the subject. |
Technology Research News April 20, 2005 |
Nanotube Chemical Sensor Gains Speed Researchers have made single-walled carbon nanotube chemical sensors that transmit information by measuring the charge in the nanotubes' capacitance, or ability to store electric charge. |
Reactive Reports May 2007 David Bradley |
A Scent for Explosives A new type of biosensor based on yeast, jellyfish proteins, and a rat's sense of smell could sniff out explosives, landmines, and agents, such as sarin gas, according to researchers. |
Chemistry World August 2, 2012 Philip Ball |
Polymer replacement for the hydration shell The sheath of water molecules, called a hydration shell, that gives protein molecules the flexibility to do their catalytic job can be replaced by polymers, according to Adam Perriman of the University of Bristol and his coworkers. |
Chemistry World November 2, 2009 Simon Hadlington |
New way to find drugs' unintended targets Researchers in the US have devised a new way to predict 'off-target' effects for pharmaceutical drugs. |
Chemistry World November 25, 2015 Philippa Matthews |
'Superballs' can block infection by Ebola virus Molecular 'superballs' have been created that can stop viruses infecting cells. |
IEEE Spectrum March 2008 Chang & Subramian |
Electronic Noses Sniff Success E-noses will soon be ubiquitous, thanks to printed organic semiconductors. |
Chemistry World April 4, 2012 Jon Evans |
Novel mass sensor is off the scale Spanish scientists have produced the world's most sensitive set of scales that should be capable of weighing a single proton. |
Chemistry World May 5, 2009 Phillip Broadwith |
Don't FRET over broken polymers Fluorescent proteins could one day help identify microscopic cracks and damage in polymer materials, allowing them to be monitored to prevent failure in load-bearing applications such as in aerospace and biomedical devices. |
Chemistry World December 9, 2013 James Urquhart |
Drug fix for misfolded proteins promises hope for incurable diseases Researchers have been looking into pharmacological chaperones or pharmacoperones. They might treat diseases brought about by genetic mutations that cause otherwise functional proteins to become misfolded or misrouted. |
Reactive Reports Apr/May 2005 David Bradley |
Of Mice and Women Mice lacking a molecule usually found on the surface of cells in the womb have fertility problems, according to a study by researchers. |
Bio-IT World September 11, 2003 Mark D. Uehling |
Fishing Chips The next generation of protein microarrays from the likes of Protometrix and Molecular Staging may threaten the early leads of Biacore and Ciphergen -- and work so well that drug companies won't want them. |
Chemistry World September 25, 2009 Simon Hadlington |
New MRI protein probe Researchers in Japan have invented a new way to detect the presence of proteins in cells and tissues by magnetic resonance imaging. |
Chemistry World June 1, 2010 Simon Hadlington |
Structural order gained over conducting polymer Scientists in Canada and the US have shown how it is possible to assemble ordered arrays of short chains of a commercially important conducting polymer on a metal surface. |
Chemistry World February 2009 Philip Ball |
Column: The crucible The flowery language of fragrance chemistry doesn't distract the author from the sharp scent of olfactory understanding |
Technology Research News September 24, 2003 Kimberly Patch |
Heated plastic holds proteins One important task for biochips is sorting proteins, but it's tricky business getting protein molecules to be where you want them and stay away from where you don't. A tiny, plastic-coated hot plate allows scientists to trap and release proteins on command. |
Technology Research News December 3, 2003 Kimberly Patch |
DNA assembles nanotube transistor Scientists have caused a transistor to self-assemble from a test tube concoction of DNA, proteins, antibodies, carbon nanotubes and minuscule specks of silver and gold. The feat shows that it is possible to assemble the smallest of machines and electronic devices by harnessing DNA's properties. |
HHMI Bulletin Nov 2011 Nicole Kresge |
Unlocking the Interferon Puzzle Scientists show that interferon signaling depends on bond strength. |
Technology Research News November 3, 2004 |
Coated Nanotubes Record Light Researchers have combined minuscule carbon nanotube transistors and photosensitive polymer to make a fast optoelectronic memory device that promises to speed digital photography and provide high-density data storage. |
Industrial Physicist |
Biomimetic Nanotechnology Although biomimetic nanotechnology is in its infancy, with no applications yet reaching commercialization, the barriers in some cases lie mainly in scaling up production processes to industrial levels. |
Chemistry World July 2, 2013 Jeanne Therese Andres |
Mapping receptors in the brain Scientists from the UK and Germany have developed new compounds that target and bind to brain proteins linked to serious neurological disorders. |
Chemistry World May 26, 2010 Phillip Broadwith |
Pain target enzyme's working made crystal clear An enzyme that influences how we feel pain and is a potential target for treating anxiety has been crystallised and its structure solved by US scientists. |
Technology Research News October 8, 2003 |
Nanotubes harvest electrons Researchers from the University of Bologna and the University of Trieste in Italy, and the University of Notre Dame have found a way to alter carbon nanotubes so that they efficiently separate electrical charge. The method could lead to more efficient solar cells. |
Chemistry World December 2007 Derek Lowe |
Column: In the Pipeline The challenge of biologics. |
Chemistry World October 28, 2008 Hayley Birch |
Drug sandwich baits E. coli toxins Polymer scaffolds that pin molecules together at multiple binding sites can trap and destroy E. coli toxins by locking them to immune proteins, researchers based in Canada and Japan have found. |