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Chemistry World March 6, 2011 Mike Brown |
Molecules that walk, hop and jump 'Two legged' molecules walk, hop and fly across a receptor surface, according to researchers in the Netherlands and Ireland. The findings could help us understand how viruses and bacteria interact with cell membranes, they say. |
Chemistry World January 13, 2008 Ananyo Bhattacharya |
Unexpected Effects of Drug Combinations Medicines that use a combination of several drugs can sometimes produce unexpected effects in patients. Now, a team of scientists think they have figured out how that can happen. |
Chemistry World October 25, 2007 |
Elusive Drug Target Finally Seen Scientists have captured an atomic-scale picture of a receptor protein from a family that is the target of thousands of drugs. |
Technology Research News March 23, 2005 |
Nanowires track molecular activity Researchers from Harvard University have found a way to use transistors made from silicon nanowires to gain information about how small molecules bind to proteins. |
Chemistry World February 12, 2009 Simon Hadlington |
Mystery receptor's binding partner uncovered For decades scientists have puzzled over the role of the sigma-1 receptor, a protein found in almost all mammalian cells, including the nervous system. |
Chemistry World February 28, 2008 James Mitchell Crow |
Chloride Ions in a Bind Chemists in the US have designed a donut-shaped molecule that tightly binds negatively-charged chloride ions. |
Chemistry World January 5, 2009 Hayley Birch |
How to Strengthen the Taste of Umami US scientists say they have uncovered a unique mechanism by which molecules drastically enhance umami flavour - the savoury taste associated with protein-rich foods such as meat, cheese and seafood. |
Chemistry World July 2, 2013 Jeanne Therese Andres |
Mapping receptors in the brain Scientists from the UK and Germany have developed new compounds that target and bind to brain proteins linked to serious neurological disorders. |
Managed Care May 2004 Thomas Morrow |
New Agents Regulating Tyrosine Kinase Can Be Used Against Several Cancers When traditional therapies fail in cancer treatment, turning off a chemical switch may offer hope to the hopeless. |
Chemistry World November 6, 2009 Phillip Broadwith |
Enzyme binds both sides of the mirror European chemists have discovered that both mirror-image forms of a particular compound can bind at the same time in the same site of an enzyme, a phenomenon that has never been seen before. |
Prepared Foods October 2007 Paula Frank |
Article: Advancing Sweeteners: The Mystery of Sweet Taste Food scientists continue their search for the "Holy Grail" of ingredients that both function and taste exactly like sugar. |
HHMI Bulletin Feb 2012 Nicole Kresge |
Now You See It, Now You Don't A disappearing receptor could hold the key to beta-cell growth and insulin production. |
Chemistry World March 4, 2015 Philip Ball |
Program ready to weed out tough drug leads A method for reliably predicting how well a candidate drug molecule will bind to its target receptor would allow libraries of molecules to be screened on the computer, without having to synthesize them all. |
Reactive Reports Issue 51 David Bradley |
Cannabinoids and Osteoporosis Researchers have discovered a regulatory mechanism involved in bone loss linked to a chemical receptor in our bodies with a previously unknown function, which could lead to a new treatment. |
HHMI Bulletin Winter 2013 Sarah Goforth |
Rational Exuberance Trained as a cardiologist, Robert Lefkowitz is the first to admit that his 39-year research career has been driven by more than a desire to treat coronary disease. He has always had an unshakeable urge to figure things out. |
Chemistry World March 17, 2009 Phillip Broadwith |
Electronic 'nose' could shed light on sense of smell Korean researchers have combined human smell receptors with nanotechnology to create a new kind of 'bio-electronic nose' |
Reactive Reports Apr/May 2005 David Bradley |
Of Mice and Women Mice lacking a molecule usually found on the surface of cells in the womb have fertility problems, according to a study by researchers. |
Chemistry World December 9, 2013 James Urquhart |
Drug fix for misfolded proteins promises hope for incurable diseases Researchers have been looking into pharmacological chaperones or pharmacoperones. They might treat diseases brought about by genetic mutations that cause otherwise functional proteins to become misfolded or misrouted. |
Chemistry World August 2009 Philip Ball |
Column: The crucible Zinc nanoparticles appear to have the ability to make odorants smell stronger and could a give a valuable insight into how olfaction works |
Chemistry World February 23, 2009 Nina Notman |
Resistant breast cancers re-sensitised to Tamoxifen A way to re-sensitise certain drug-resistant breast cancers to treatments such as Tamoxifen could offer better treatment for people with hard-to-beat cancers. |
Chemistry World August 31, 2007 Lionel Milgrom |
Gut's Taste for the Sweet Life Revealed A sugar-sensing receptor in the intestine could explain why drinking diet cola may hinder obese people who hope to lose weight and lead to new ways of treating obesity and diabetes. |
Chemistry World February 27, 2007 Jon Evans |
Molecular pH Sensor Inspired by Relay Runners Chemists have taken inspiration from relay runners to create a molecular version of a conventional glass pH electrode. Their molecular sensor can measure pH over a wide range and should allow scientists to begin measuring pH levels in microscopic volumes, such as within individual cells. |