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Chemistry World December 9, 2013 James Urquhart |
Drug fix for misfolded proteins promises hope for incurable diseases Researchers have been looking into pharmacological chaperones or pharmacoperones. They might treat diseases brought about by genetic mutations that cause otherwise functional proteins to become misfolded or misrouted. |
Chemistry World January 13, 2008 Ananyo Bhattacharya |
Unexpected Effects of Drug Combinations Medicines that use a combination of several drugs can sometimes produce unexpected effects in patients. Now, a team of scientists think they have figured out how that can happen. |
Chemistry World March 6, 2011 Mike Brown |
Molecules that walk, hop and jump 'Two legged' molecules walk, hop and fly across a receptor surface, according to researchers in the Netherlands and Ireland. The findings could help us understand how viruses and bacteria interact with cell membranes, they say. |
Salon.com August 21, 2000 Lori B. Andrews |
Embryos under the knife The latest reproductive technology is just the next step on our sprint toward human cloning. |
Chemistry World February 23, 2009 Nina Notman |
Resistant breast cancers re-sensitised to Tamoxifen A way to re-sensitise certain drug-resistant breast cancers to treatments such as Tamoxifen could offer better treatment for people with hard-to-beat cancers. |
HHMI Bulletin Feb 2012 Nicole Kresge |
Now You See It, Now You Don't A disappearing receptor could hold the key to beta-cell growth and insulin production. |
Chemistry World August 29, 2008 John Bonner |
Chip test for IVF embryos US researchers may have found a new way to assess the health of embryos produced by in vitro fertilization, using a lab on a chip approach to measure their uptake of nutrients. |
Chemistry World July 2, 2013 Jeanne Therese Andres |
Mapping receptors in the brain Scientists from the UK and Germany have developed new compounds that target and bind to brain proteins linked to serious neurological disorders. |
Chemistry World October 18, 2012 |
A signal honor The 2012 Nobel prize in chemistry was awarded to Robert Lefkowitz and Brian Kobilka for studies of G-protein-coupled receptors. This article looks at the molecular machinery underpinning cell signaling. |
Chemistry World October 25, 2007 |
Elusive Drug Target Finally Seen Scientists have captured an atomic-scale picture of a receptor protein from a family that is the target of thousands of drugs. |
Managed Care May 2004 Thomas Morrow |
New Agents Regulating Tyrosine Kinase Can Be Used Against Several Cancers When traditional therapies fail in cancer treatment, turning off a chemical switch may offer hope to the hopeless. |
Chemistry World February 12, 2009 Simon Hadlington |
Mystery receptor's binding partner uncovered For decades scientists have puzzled over the role of the sigma-1 receptor, a protein found in almost all mammalian cells, including the nervous system. |
Chemistry World July 21, 2011 Elinor Richards |
Cell Control to Change Cell Function US scientists can now control the reactions occurring inside cells. |
BusinessWeek February 27, 2006 Catherine Arnst |
And Baby Makes...A Market "The Baby Business: How Money, Science, and Politics Drive the Commerce of Conception" is a valuable, thought-provoking look at the baby-making business. |
HHMI Bulletin February 2011 Sarah C.P. Williams |
Forgetting Fear A compound given at just the right time may make mice forget to be afraid. |
Chemistry World January 31, 2007 Victoria Gill |
LSD reveals its secrets A long-standing pharmacological mystery surrounding hallucinogens may finally have been solved by a new study. |
HHMI Bulletin Feb 2012 Mary Bates |
Passing the Sniff Test Researchers are mapping the chemical signaling behind how mice detect friend and foe. |
Chemistry World March 17, 2009 Phillip Broadwith |
Electronic 'nose' could shed light on sense of smell Korean researchers have combined human smell receptors with nanotechnology to create a new kind of 'bio-electronic nose' |
Chemistry World September 2010 |
Repulsive chemistry Simon Hadlington discovers why some people get bitten by more insects than others, and how new chemical deterrents are helping fight them off |
Chemistry World February 3, 2015 Jennifer Newton |
Chip-on-a-cell Colleagues at the Institute of Microelectronics Barcelona affixed polysilicon chips, which act as barcodes, onto the outer surface of the zona pellucida, a membrane that surrounds immature egg.cells and embryos. |
HHMI Bulletin Nov 2011 Nicole Kresge |
Unlocking the Interferon Puzzle Scientists show that interferon signaling depends on bond strength. |
Chemistry World October 1, 2007 Victoria Gill |
Anorexia Shares Addictive Pathway with Ecstasy Researchers in France have discovered that anorexia and MDMA share a common signaling pathway in the brain - both reducing the drive to eat by stimulating the same subset of receptors for the neurotransmitter serotonin. |
Popular Mechanics January 2010 Amber Angelle |
How to Create a Designer Baby Women undergoing in vitro fertilization could one day choose to have a baby boy with perfect vision, an aptitude for sports and a virtual lock on avoiding colon cancer. |
HHMI Bulletin Winter 2013 Sarah Goforth |
Rational Exuberance Trained as a cardiologist, Robert Lefkowitz is the first to admit that his 39-year research career has been driven by more than a desire to treat coronary disease. He has always had an unshakeable urge to figure things out. |
ifeminists September 22, 2004 |
Fertility Tourism Many aspiring parents dislike the laws that control fertility in the UK and are attracted by the more flexible foreign policies. |
Reactive Reports Issue 35 David Bradley |
Teen Gene A puberty gene called "Harry Potter" has been discovered by UK and US scientists. |
Salon.com May 3, 1999 Dawn MacKeen |
The Clone Age Adventures in the new world of reproductive technology... |
Scientific American August 2008 Christine Soares |
Nicotine Replacement Drug's Bad Trip Pfizer's smoking-cessation aid tied to psychiatric episodes. |
Reactive Reports Issue 51 David Bradley |
Cannabinoids and Osteoporosis Researchers have discovered a regulatory mechanism involved in bone loss linked to a chemical receptor in our bodies with a previously unknown function, which could lead to a new treatment. |
American Family Physician May 15, 2003 |
What Should I Know About Male Infertility? What is infertility?... How often are male factors involved?... What causes male infertility?... When should I see a doctor?... Should men be checked for infertility?... How is infertility evaluated?... Is male infertility treatable?... Where can I get more information? |
Chemistry World February 27, 2007 Jon Evans |
Molecular pH Sensor Inspired by Relay Runners Chemists have taken inspiration from relay runners to create a molecular version of a conventional glass pH electrode. Their molecular sensor can measure pH over a wide range and should allow scientists to begin measuring pH levels in microscopic volumes, such as within individual cells. |
Chemistry World August 31, 2007 Lionel Milgrom |
Gut's Taste for the Sweet Life Revealed A sugar-sensing receptor in the intestine could explain why drinking diet cola may hinder obese people who hope to lose weight and lead to new ways of treating obesity and diabetes. |