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Chemistry World
May 23, 2013
Rachel Cooper
The power of multivalency against cholera An international team of scientists has synthesized a cholera inhibitor that matches both the valency and target sugar of the cholera toxin. The molecule is 100,000 times better at trapping the cholera toxin than inhibitors based on the target sugar alone. mark for My Articles similar articles
Chemistry World
December 3, 2013
Simon Hadlington
Caged toxin for safer, better bacterial vaccines Researchers in the US have developed a new way of vaccinating against bacterial toxins by caging them in hybrid nanoparticles. mark for My Articles similar articles
Chemistry World
June 24, 2014
Elisabeth Ratcliffe
Human protein cleans drinking water Researchers in Japan have shown that they can remove Escherichia coli from drinking water using tiny tubes made of human serum albumin. mark for My Articles similar articles
Chemistry World
February 12, 2014
Manisha Lalloo
Synthetic strategy targets 'undruggable' small RNAs Chemists in the US have found a way to predict small molecules that can target short pieces of RNA involved in some diseases, such as cancer. mark for My Articles similar articles
Chemistry World
June 9, 2008
Simon Hadlington
Artificial virus silences genes Scientists in Korea have created an artificial virus that can target the nucleus of cancer cells and knock out specific genes. mark for My Articles similar articles
National Defense
November 2010
Eric Beidel
To Counter Bioterrorism, The Key is Boosting Immunity That's why Texas A&M University researchers are investigating ways to arm Americans against attacks involving toxins, viruses and bacteria. mark for My Articles similar articles
Chemistry World
December 12, 2011
Simon Hadlington
Zwitterion approach to stabilizing drug proteins Researchers in the US have discovered a new way to stabilize and protect protein molecules without affecting the protein's biological activity. mark for My Articles similar articles
Chemistry World
June 23, 2015
Derek Lowe
Missing the target There are enzymes that no mustard has ever cut, to steal a phrase from science fiction author James Blish. Phosphatases, the flip side of kinase activity, are a perfect example. mark for My Articles similar articles
Chemistry World
May 7, 2014
Emma Stoye
Bacterium survives unnatural DNA transplant The first organism that can grow and replicate with an unnatural base pair in its DNA -- giving the cell six nucleotides instead of the usual four -- has been created by scientists in the US. mark for My Articles similar articles
HHMI Bulletin
February 2011
Sarah C.P. Williams
Enforcing Order Changing the spatial arrangement of molecules in a cell can alter their functions. mark for My Articles similar articles
The Motley Fool
June 29, 2011
Brian Orelli
4 Immunotherapies to Watch Just don't go all-in. mark for My Articles similar articles
Chemistry World
September 2, 2007
Simon Hadlington
Sweet Approach to Tackling Cancer A promising new 'slimline' cancer vaccine that triggers a powerful immune response against excessive sugar molecules has been unveiled by researchers. mark for My Articles similar articles
HHMI Bulletin
Aug 2011
Richard Saltus
T-Cell Booster Kits A bioengineer remodels cell surfaces to prod the immune system. mark for My Articles similar articles
Chemistry World
July 21, 2011
Elinor Richards
Cell Control to Change Cell Function US scientists can now control the reactions occurring inside cells. mark for My Articles similar articles
AskMen.com
Jacob Franek
New Cancer Therapies As cancer research explodes, the availability of new and innovative interventions is expanding almost daily. mark for My Articles similar articles
Chemistry World
March 4, 2015
Philip Ball
Program ready to weed out tough drug leads A method for reliably predicting how well a candidate drug molecule will bind to its target receptor would allow libraries of molecules to be screened on the computer, without having to synthesize them all. mark for My Articles similar articles
Chemistry World
October 31, 2010
Michael Gross
Kiss of death for cancer cells Scientists have deciphered the surprising structure of the perforin pore, which delivers the 'kiss of death' to virus-infected cells and cancer cells in the body. mark for My Articles similar articles
Chemistry World
August 26, 2008
Photonic crystal drug detective A new high-throughput screening system based on photonic crystals could quickly and cheaply detect molecules that disrupt binding between proteins and DNA. mark for My Articles similar articles
Chemistry World
November 25, 2013
Carla Pegoraro
Steering cells towards biocomputers Bacterial toxins that undergo unique cell interactions have been used to perform logic functions by researchers in Germany. This innovation will help push the limits of synthetic biology. mark for My Articles similar articles
Chemistry World
June 1, 2009
Phillip Broadwith
Wider therapeutic possibilities for botulinum toxin Change to a single amino acid in botulinum toxin A causes it to target non-neuronal signalling proteins, potentially widening the product's therapeutic applications mark for My Articles similar articles
Chemistry World
May 10, 2013
Michael Parkin
Super Glue for cells Scientists in Canada have made a super-strong cell membrane adhesive and used it to stick red blood cells together. The polymer, based on the phospholipid head group phosphatidyl choline, could be used to secure cells in particular positions for tissue engineering and wound closure. mark for My Articles similar articles
Chemistry World
February 13, 2014
Philip Ball
Ice core to antifreeze protein's inner workings The antifreeze protein that protects the winter flounder from sub-zero temperatures has been found to have an odd structure. mark for My Articles similar articles
HHMI Bulletin
May 2012
Elise Lamar
Cells on the Move The biochemical signals that set cells on a journey are as diverse as the tissues they move through, but the engine is driven by constant remodeling of a protein network built from a box of cellular Legos. mark for My Articles similar articles
Bio-IT World
July 15, 2003
Julia Boguslavsky
'Fingerprinting' a Single Cell Single-cell proteomics is finally within reach, thanks to a professor of analytical chemistry. mark for My Articles similar articles
Chemistry World
March 21, 2014
Richard Massey
Magnetic field and pH synergy controls therapeutic burst Australian researchers have shown how alternating magnetic fields could be used to localize the release of cancer-fighting drugs to cancer cells, limiting side effects in the rest of the body. mark for My Articles similar articles
Chemistry World
May 5, 2009
Phillip Broadwith
Don't FRET over broken polymers Fluorescent proteins could one day help identify microscopic cracks and damage in polymer materials, allowing them to be monitored to prevent failure in load-bearing applications such as in aerospace and biomedical devices. mark for My Articles similar articles
Chemistry World
August 2, 2012
Philip Ball
Polymer replacement for the hydration shell The sheath of water molecules, called a hydration shell, that gives protein molecules the flexibility to do their catalytic job can be replaced by polymers, according to Adam Perriman of the University of Bristol and his coworkers. mark for My Articles similar articles
Technology Research News
June 29, 2005
Self-assembly: the natural way to make things In biology, there are a few different ways DNA molecules can be replicated and combined. mark for My Articles similar articles
Chemistry World
November 27, 2013
Jennifer Newton
A cytochrome from scratch Artificial proteins could be closer to participating in natural biochemical pathways after researchers show that bacteria will process amino acid sequences entirely unrelated to any natural protein to produce a fully functioning cytochrome. mark for My Articles similar articles
Chemistry World
October 2, 2012
Fiona McKenzie
Protein sorting within cells US scientists have used magnetic nanoparticles with specific ligands to latch on to and visualize specific proteins in living cells. mark for My Articles similar articles
Chemistry World
July 1, 2013
James Urquhart
Antibiotic research hits a sweet spot UK researchers have found a way to weaken the molecular armour of Escherichia coli to allow the host's immune system to attack and kill the pathogen. mark for My Articles similar articles
Chemistry World
July 29, 2015
Thadchajini Retneswaran
Antifreeze polymer protects cells as they thaw Researchers have synthesized a polymer that limits ice crystal growth in frozen red blood cells as they thaw. mark for My Articles similar articles
Chemistry World
March 5, 2012
Harriet Brewerton
Picturing Bacteria on Your Phone US scientists have developed a device that, when attached to a mobile phone, can detect small amounts of Escherichia coli in liquid samples. mark for My Articles similar articles
Chemistry World
July 24, 2012
Rachel Cooper
Light speeds up new cell growth Scientists from Singapore have combined a photovoltaic polymer with a biocompatible polymer to make a nanofiber-based scaffold that can grow cells for skin regeneration. mark for My Articles similar articles
Chemistry World
September 30, 2010
Andrew Turley
Bacteria factories for Taxol precursors Researchers have engineered bacteria to produce precursors of Taxol (paclitaxel), one of the most widely used cancer drugs. mark for My Articles similar articles
HHMI Bulletin
May 2010
Sarah C.P. Williams
Lab-Grown Liver New cell culture system solves problem of growing liver cells. mark for My Articles similar articles
Chemistry World
September 19, 2007
Lewis Brindley
Cell Destruction by Gel Implosion Scientists in Hong Kong have shown that creating a gel inside bacterial cells can stunt their growth. This research is a step towards developing novel treatments that would target rapidly-reproducing cells such antibiotic-resistant superbugs. mark for My Articles similar articles
Chemistry World
December 11, 2008
Hayley Birch
Protein threading paves the way for nanomachines A team of Dutch and Italian researchers has discovered how proteins are threaded through pores in cell membranes. mark for My Articles similar articles
Reactive Reports
Issue 56
Jeffrey Krise
A Basic Approach to Chemotherapy Chemists have found a way to attack malignant cells with an anticancer drug, while sparing healthy cells. mark for My Articles similar articles
Chemistry World
March 17, 2009
Phillip Broadwith
Electronic 'nose' could shed light on sense of smell Korean researchers have combined human smell receptors with nanotechnology to create a new kind of 'bio-electronic nose' mark for My Articles similar articles
Chemistry World
February 18, 2008
John Bonner
Flicking the Acetyl Switch A strain of Escherichia coli that can produce proteins containing an acetylated version of the amino acid lysine could help to reveal how acetylation changes the function of hundreds of proteins inside cells. mark for My Articles similar articles
Pharmaceutical Executive
July 30, 2007
Tomorrow's Drugs A look at the seven top therapies and technologies vying to deliver the next generation of drugs. mark for My Articles similar articles
Scientific American
July 3, 2006
Jeneen Interlandi
An Immune Portal Protein may be a key to autoimmune disorders mark for My Articles similar articles
Chemistry World
June 20, 2013
Jennifer Newton
Students develop antivenom in high school lab A US high school teacher and nine of his students have made nanoparticles that can neutralize venom from one of the most dangerous snakes in Africa. These nanoparticles could offer a way to make cheaper and more practical antivenoms. mark for My Articles similar articles
Chemistry World
December 2007
Derek Lowe
Column: In the Pipeline The challenge of biologics. mark for My Articles similar articles
Chemistry World
February 24, 2012
Simon Hadlington
Botox 'bodyguard' gives protein protection Researchers have discovered how one of the most potent toxins known to man can survive in the human stomach and digestive tract. mark for My Articles similar articles
Popular Mechanics
January 28, 2010
Cassie Rodenberg
Next-Gen Transplant Techniques Can Stop Organ Rejection About 77 organ transplants are performed each day in the U.S., and more than 101,000 people are on a wait list for body parts such as hearts, skin and veins, according to the Mayo Clinic. mark for My Articles similar articles
Chemistry World
April 23, 2010
Lewis Brindley
Ricin antidote on the horizon For the first time, compounds that protect against ricin poisoning have been identified by French researchers. mark for My Articles similar articles
Science News
January 15, 2005
Christen Brownlee
The Beef about UTIs E. coli from beef cattle or other livestock may be causing drug-resistant urinary tract infections in women. mark for My Articles similar articles
Chemistry World
July 28, 2009
Michael Gross
DNA to direct and switch off chemo Researchers in the US have developed a new approach to cancer chemotherapy using short DNA strands to help target delivery of the drug directly to cancer cells, and 'call it off' should problems arise. mark for My Articles similar articles